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Volumn 106, Issue 17, 2009, Pages 7119-7124

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

Author keywords

Cytokines; Inflammasome; Th1; Th17; Th2

Indexed keywords

ANTIGEN; CD28 ANTIGEN; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN; INTERLEUKIN 1 RECEPTOR TYPE I;

EID: 66349089266     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902745106     Document Type: Article
Times cited : (460)

References (36)
  • 1
    • 58049209834 scopus 로고    scopus 로고
    • Joffre O, Nolte MA, Spö rri R, Reis e Sousa C (2009) Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev 227:234-247.
    • Joffre O, Nolte MA, Spö rri R, Reis e Sousa C (2009) Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev 227:234-247.
  • 2
    • 66449109344 scopus 로고    scopus 로고
    • Interleukin-1 family of ligands and receptors
    • ed Paul WE Lippincott Williams & Wilkins, Philadelphia, 6th Ed
    • Dinarello CA (2008) Interleukin-1 family of ligands and receptors. In Fundamental Immunology, ed Paul WE (Lippincott Williams & Wilkins, Philadelphia), 6th Ed.
    • (2008) Fundamental Immunology
    • Dinarello, C.A.1
  • 3
    • 33750348545 scopus 로고    scopus 로고
    • Endogenous IL-1R1 signaling is critical for cognate CD4- T cell help for induction of in vivo type 1 and type 2 antipolysaccharide and antiprotein Ig isotype responses to intact Streptococcus pneumoniae, but not to a soluble pneumococcal conjugate vaccine
    • Chen Q, Sen G, Snapper CM (2006) Endogenous IL-1R1 signaling is critical for cognate CD4- T cell help for induction of in vivo type 1 and type 2 antipolysaccharide and antiprotein Ig isotype responses to intact Streptococcus pneumoniae, but not to a soluble pneumococcal conjugate vaccine. J Immunol 177:6044-6051.
    • (2006) J Immunol , vol.177 , pp. 6044-6051
    • Chen, Q.1    Sen, G.2    Snapper, C.M.3
  • 4
    • 0242584867 scopus 로고    scopus 로고
    • IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis
    • Zwijnenburg PJ, et al. (2003) IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis. J Immunol 170:4724-4730.
    • (2003) J Immunol , vol.170 , pp. 4724-4730
    • Zwijnenburg, P.J.1
  • 5
    • 18144380291 scopus 로고    scopus 로고
    • Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection
    • Schmitz N, Kurrer M, Bachmann MF, Kopf M (2005) Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection. J Virol 79:6441-6448.
    • (2005) J Virol , vol.79 , pp. 6441-6448
    • Schmitz, N.1    Kurrer, M.2    Bachmann, M.F.3    Kopf, M.4
  • 6
    • 34250370957 scopus 로고    scopus 로고
    • IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression
    • Koziczak-Holbro M, et al. (2007) IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression. J Biol Chem 282:13552-13560.
    • (2007) J Biol Chem , vol.282 , pp. 13552-13560
    • Koziczak-Holbro, M.1
  • 7
    • 34948904198 scopus 로고    scopus 로고
    • Selective predisposition to bacterial infections in IRAK-4 deficient children: IRAK-4 dependent TLRs are otherwise redundant in protective immunity
    • Ku CL, et al. (2007) Selective predisposition to bacterial infections in IRAK-4 deficient children: IRAK-4 dependent TLRs are otherwise redundant in protective immunity. J Exp Med 204:2407-2422.
    • (2007) J Exp Med , vol.204 , pp. 2407-2422
    • Ku, C.L.1
  • 8
    • 0037389680 scopus 로고    scopus 로고
    • Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1Ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial
    • Fleischmann RM, et al. (2003) Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1Ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum 48:927-934.
    • (2003) Arthritis Rheum , vol.48 , pp. 927-934
    • Fleischmann, R.M.1
  • 9
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F (2007) Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 8:942-949.
    • (2007) Nat Immunol , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 10
    • 40049098958 scopus 로고    scopus 로고
    • IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
    • Aujla SJ, et al. (2008) IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med 14:275-281.
    • (2008) Nat Med , vol.14 , pp. 275-281
    • Aujla, S.J.1
  • 11
    • 0037442115 scopus 로고    scopus 로고
    • CD4- T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism
    • Chung DR, et al. (2003) CD4- T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism. J Immunol 170:1958-1963.
    • (2003) J Immunol , vol.170 , pp. 1958-1963
    • Chung, D.R.1
  • 12
    • 11144286392 scopus 로고    scopus 로고
    • Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection
    • Kelly MN, et al. (2005) Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun 73:617-621.
    • (2005) Infect Immun , vol.73 , pp. 617-621
    • Kelly, M.N.1
  • 13
    • 3242814586 scopus 로고    scopus 로고
    • Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
    • Huang W, Na L, Fidel PL, Schwarzenberger P (2004) Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis 190:624-631.
    • (2004) J Infect Dis , vol.190 , pp. 624-631
    • Huang, W.1    Na, L.2    Fidel, P.L.3    Schwarzenberger, P.4
  • 14
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4- T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader SA, et al. (2007) IL-23 and IL-17 in the establishment of protective pulmonary CD4- T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 8:369-377.
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1
  • 15
    • 41449110468 scopus 로고    scopus 로고
    • Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
    • Milner JD, et al. (2008) Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 452:773-776.
    • (2008) Nature , vol.452 , pp. 773-776
    • Milner, J.D.1
  • 16
    • 0031570928 scopus 로고    scopus 로고
    • Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4- T cells
    • Pape KA, Khoruts A, Mondino A, Jenkins MK (1997) Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4- T cells. J Immunol 159:591-598.
    • (1997) J Immunol , vol.159 , pp. 591-598
    • Pape, K.A.1    Khoruts, A.2    Mondino, A.3    Jenkins, M.K.4
  • 17
    • 3843068987 scopus 로고    scopus 로고
    • IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands
    • Khoruts A, Osness RE, Jenkins MK (2004) IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands. Eur J Immunol 34:1085-1090.
    • (2004) Eur J Immunol , vol.34 , pp. 1085-1090
    • Khoruts, A.1    Osness, R.E.2    Jenkins, M.K.3
  • 18
    • 0344737674 scopus 로고    scopus 로고
    • Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: Different roles of ERK and NF-kappaB signaling pathways
    • Guo Z, et al. (2003) Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: Different roles of ERK and NF-kappaB signaling pathways. Blood 102:4441-4447.
    • (2003) Blood , vol.102 , pp. 4441-4447
    • Guo, Z.1
  • 19
    • 0037080186 scopus 로고    scopus 로고
    • IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): A mechanism for T cell-independent DC activation
    • Luft T, et al. (2002) IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): A mechanism for T cell-independent DC activation. J Im-munol 168:713-722.
    • (2002) J Im-munol , vol.168 , pp. 713-722
    • Luft, T.1
  • 20
    • 2542434337 scopus 로고    scopus 로고
    • A Increased production of proinflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand
    • Wesa A, Galy (2002) A Increased production of proinflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand. BMC Immunol 3:14.
    • (2002) BMC Immunol , vol.3 , pp. 14
    • Wesa, A.1    Galy2
  • 21
    • 0032184763 scopus 로고    scopus 로고
    • Detectionofahighfrequencyofvirus-specificCD4- Tcellsduring acute infection with lymphocytic choriomeningitis virus
    • VargaSM,WelshRM(1998)Detectionofahighfrequencyofvirus-specificCD4- Tcellsduring acute infection with lymphocytic choriomeningitis virus. J Immunol 161:3215-3218.
    • (1998) J Immunol , vol.161 , pp. 3215-3218
    • Varga, S.M.1    Welsh, R.M.2
  • 22
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immuno-stimulatory properties of aluminium adjuvants
    • Eisenbarth SC, et al. (2008) Crucial role for the Nalp3 inflammasome in the immuno-stimulatory properties of aluminium adjuvants. Nature 453:1122-1126.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1
  • 23
    • 38449101266 scopus 로고    scopus 로고
    • IL-1β and IL-1β are endogenous mediators linking cell injury to the adaptive alloimmune response
    • Rao DA, Tracey KJ, Pober JS (2007) IL-1β and IL-1β are endogenous mediators linking cell injury to the adaptive alloimmune response. J Immunol 179:6536-6546.
    • (2007) J Immunol , vol.179 , pp. 6536-6546
    • Rao, D.A.1    Tracey, K.J.2    Pober, J.S.3
  • 24
    • 0027251023 scopus 로고
    • Murine T helper cell-2 lymphocytes express type I and type II IL-1 receptors, but only the type I receptor mediates costimulatory activity
    • McKean DJ, et al. (1993) Murine T helper cell-2 lymphocytes express type I and type II IL-1 receptors, but only the type I receptor mediates costimulatory activity. J Immunol 151:3500-3510.
    • (1993) J Immunol , vol.151 , pp. 3500-3510
    • McKean, D.J.1
  • 25
    • 0028337202 scopus 로고
    • Expression of the IL-1 receptor discriminates Th2 from Th1 cloned CD4-T cells specific for Plasmodium chabaudi
    • Taylor-Robinson AW, Phillips RS (1994) Expression of the IL-1 receptor discriminates Th2 from Th1 cloned CD4-T cells specific for Plasmodium chabaudi. Immunology 81:216-221.
    • (1994) Immunology , vol.81 , pp. 216-221
    • Taylor-Robinson, A.W.1    Phillips, R.S.2
  • 26
    • 7044274793 scopus 로고    scopus 로고
    • Aluminium compounds for use in vaccines
    • Lindblad EB (2004) Aluminium compounds for use in vaccines. Immunol Cell Biol 82:497-505.
    • (2004) Immunol Cell Biol , vol.82 , pp. 497-505
    • Lindblad, E.B.1
  • 27
    • 10944261462 scopus 로고    scopus 로고
    • Interleukin 1 plays a major role in the development of Th2-mediated immunity
    • Helmby H, Grencis R (2004) Interleukin 1 plays a major role in the development of Th2-mediated immunity. Eur J Immunol 34:3674-3681.
    • (2004) Eur J Immunol , vol.34 , pp. 3674-3681
    • Helmby, H.1    Grencis, R.2
  • 28
    • 0023731856 scopus 로고
    • The distribution and clearance of radiolabeled human interleukin-1 beta in mice
    • Newton RC, Uhl J, Covington M, Back O (1988) The distribution and clearance of radiolabeled human interleukin-1 beta in mice. Lymphokine Res 7:207-216.
    • (1988) Lymphokine Res , vol.7 , pp. 207-216
    • Newton, R.C.1    Uhl, J.2    Covington, M.3    Back, O.4
  • 29
    • 0024360388 scopus 로고
    • The biology of interleukin-6
    • Kishimoto T (1989) The biology of interleukin-6. Blood 74:1-10.
    • (1989) Blood , vol.74 , pp. 1-10
    • Kishimoto, T.1
  • 30
    • 17044377812 scopus 로고    scopus 로고
    • IL-6 increases primed cell expansion and survival
    • Rochman I, Paul WE, Ben-Sasson SZ (2005) IL-6 increases primed cell expansion and survival. J Immunol 174:4761-4767.
    • (2005) J Immunol , vol.174 , pp. 4761-4767
    • Rochman, I.1    Paul, W.E.2    Ben-Sasson, S.Z.3
  • 31
    • 33846122035 scopus 로고    scopus 로고
    • The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4- T cells and enables CpG oligodeoxynucleotide-mediated costimulation
    • Gelman AE, et al. (2006) The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4- T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity 25:783-793.
    • (2006) Immunity , vol.25 , pp. 783-793
    • Gelman, A.E.1
  • 32
    • 0034663779 scopus 로고    scopus 로고
    • The NF-{kappa}B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4- lymphocytes
    • Khoshnan A, et al. (2000) The NF-{kappa}B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4- lymphocytes. J Immunol 165:1743-1754.
    • (2000) J Immunol , vol.165 , pp. 1743-1754
    • Khoshnan, A.1
  • 33
    • 0038744514 scopus 로고    scopus 로고
    • The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model
    • Schmitz N, Kurrer M, Kopf M (2003) The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model. Eur J Immunol 33:991-1000.
    • (2003) Eur J Immunol , vol.33 , pp. 991-1000
    • Schmitz, N.1    Kurrer, M.2    Kopf, M.3
  • 34
    • 0032077870 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells
    • Badovinac V, Mostarica-Stojkovic M, Dinarello CA, Stosic-Grujicic S (1998) Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells. J Neu-roimmunol 85:87-95.
    • (1998) J Neu-roimmunol , vol.85 , pp. 87-95
    • Badovinac, V.1    Mostarica-Stojkovic, M.2    Dinarello, C.A.3    Stosic-Grujicic, S.4
  • 35
    • 0032995904 scopus 로고    scopus 로고
    • Effects of interleukin 1 receptor antagonist alone and in combination with methotrexate in adjuvant arthritic rats
    • Bendele A, et al. (1999) Effects of interleukin 1 receptor antagonist alone and in combination with methotrexate in adjuvant arthritic rats. J Rheumatol 26:1225-1229.
    • (1999) J Rheumatol , vol.26 , pp. 1225-1229
    • Bendele, A.1
  • 36
    • 0024328379 scopus 로고
    • Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses
    • Grun JL, Maurer PH (1989) Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses. Cell Immunol 121:134-145.
    • (1989) Cell Immunol , vol.121 , pp. 134-145
    • Grun, J.L.1    Maurer, P.H.2


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