Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions

Immunity

Volumn 32, Issue 1, 2010, Pages 116-128

  Hegazy, Ahmed N ^a,b   Peine, Michael ^a,b   Helmstetter, Caroline ^a,b   Panse, Isabel ^a,b   Fröhlich, Anja ^a,b   Bergthaler, Andreas ^c   Flatz, Lukas ^d   Pinschewer, Daniel D ^e   Radbruch, Andreas ^b   Löhning, Max ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

CELLIMMUNO

Indexed keywords

GAMMA INTERFERON; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LINEAGE; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PERSISTENT VIRUS INFECTION; PHENOTYPE; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; STABLE EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; VIREMIA; VIRUS MENINGITIS;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; CELL SEPARATION; CYTOKINES; FLOW CYTOMETRY; GATA3 TRANSCRIPTION FACTOR; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; T-BOX DOMAIN PROTEINS; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

EID: 74549179138     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2009.12.004     Document Type: Article

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