Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

Journal of Experimental Medicine

Volumn 206, Issue 3, 2009, Pages 535-548

  Boniface, Katia ^a   Bak Jensen, Kristian S ^a,b   Li, Ying ^a   Blumenschein, Wendy M ^a   McGeachy, Mandy J ^a   McClanahan, Terrill K ^a   McKenzie, Brent S ^a,c   Kastelein, Robert A ^a   Cua, Daniel J ^a   De Malefyt, René Waal ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NOVO NORDISK A S   (Denmark)

^c CSL LIMITED   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; CHEMOKINE RECEPTOR CCR6; CYCLIC AMP; GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN E4 RECEPTOR; RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR GAMMA T; UNCLASSIFIED DRUG; EP4 RECEPTOR; PROSTAGLANDIN EP2 RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TH17 CELL; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; COCULTURE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HELPER CELL; IMMUNOLOGICAL MEMORY; METABOLISM; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; CYCLIC AMP; DINOPROSTONE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-1BETA; INTERLEUKIN-23; MICE; MODELS, IMMUNOLOGICAL; RECEPTORS, CCR6; RECEPTORS, INTERLEUKIN-1; RECEPTORS, PROSTAGLANDIN E; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; UP-REGULATION;

EID: 63449127321     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20082293     Document Type: Article

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