Chemical modification of siRNA

Current Protocols in Nucleic Acid Chemistry

Volumn , Issue SUPPL. 39, 2009, Pages

  Deleavey, Glen F ^a   Watts, Jonathan K ^b   Damha, Masad J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Chemical modification; Immunostimulatory effects; Off target effects; Oligonucleotide; SiRNA

Indexed keywords

2 AMINOPURINE; 4 THIOURACIL; 5 BROMOURACIL; CHLOROBENZENE; DIHYDROFLUOROURACIL; ENOXACIN; FLUOROBENZENE; NUCLEOTIDE; SMALL INTERFERING RNA; SUGAR; THIOURACIL;

BINDING AFFINITY; CHEMICAL BINDING; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; CONJUGATION; DRUG POTENTIATION; DRUG STABILITY; GENE SILENCING; GENE TARGETING; IMMUNOSTIMULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PRIORITY JOURNAL; REVIEW; RNA HYBRIDIZATION; RNA INTERFERENCE; RNA STRUCTURE;

ANIMALS; GENE SILENCING; HUMANS; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING;

MAMMALIA;

EID: 75949125229     PISSN: 19349270     EISSN: 19349289     Source Type: Journal    
DOI: 10.1002/0471142700.nc1603s39     Document Type: Review

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