Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs

Antisense and Nucleic Acid Drug Development

Volumn 12, Issue 5, 2002, Pages 301-309

  Hamada, Makiko ^a   Ohtsuka, Toshiaki ^a   Kawaida, Reimi ^a   Koizumi, Makoto ^a   Morita, Koji ^a   Furukawa, Hidehiko ^a   Imanishi, Takeshi ^b   Miyagishi, Makoto ^c,d   Taira, Kazunari ^c,d  

^a DAIICHI SANKYO CO   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2' O,4' C ETHYLENE THYMIDINE; COMPLEMENTARY RNA; DOUBLE STRANDED RNA; ETHYLENE; JUN DIMERIZATION PROTEIN 2; MESSENGER RNA; NUCLEIC ACID; PROTEIN; RNA; SMALL INTERFERING RNA; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG; JUNDP2 PROTEIN, MOUSE; PRIMER DNA; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; CELL CULTURE; CHEMICAL MODIFICATION; DROSOPHILA; DRUG EFFECT; DRUG SYNTHESIS; DRUG TARGETING; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; MAMMAL CELL; MOUSE; MUTATION; NEMATODE; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTOZOON; ANIMAL; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALIA; ENA; MAMMALIA; NEMATODA; PROTOZOA;

ANIMALS; BASE PAIR MISMATCH; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; DNA PRIMERS; GENE EXPRESSION; GENE SILENCING; MICE; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 0036811055     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/108729002761381285     Document Type: Article

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