Effect of base modifications on structure, thermodynamic stability, and gene silencing activity of short interfering RNA

RNA

Volumn 13, Issue 8, 2007, Pages 1301-1316

  Sipa, Katarzyna ^a   Sochacka, Elzbieta ^b   Kazmierczak Baranska, Julia ^a   Maszewska, Maria ^a   Janicka, Magdalena ^a   Nowak, Genowefa ^a   Nawrot, Barbara ^a  

^a CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

2 thiouridine; Chemical modification; Duplex asymmetry; siRNA; Thermodynamic stability

Indexed keywords

BETA SECRETASE; COMPLEMENTARY RNA; GREEN FLUORESCENT PROTEIN; PSEUDOURIDINE; SMALL INTERFERING RNA;

ARTICLE; BASE PAIRING; CHEMICAL MODIFICATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANALYSIS; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; MELTING POINT; PRIORITY JOURNAL; RNA SEQUENCE; RNA STABILITY; RNA STRUCTURE; THERMODYNAMICS;

CIRCULAR DICHROISM; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; NUCLEIC ACID CONFORMATION; NUCLEOSIDES; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; THERMODYNAMICS; URIDINE;

EID: 34447507937     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.538907     Document Type: Article

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