Off-target effects by siRNA can induce toxic phenotype

RNA

Volumn 12, Issue 7, 2006, Pages 1188-1196

  Fedorov, Yuriy ^a   Anderson, Emily M ^a   Birmingham, Amanda ^a   Reynolds, Angela ^a   Karpilow, Jon ^a   Robinson, Kathryn ^a   Leake, Devin ^a   Marshall, William S ^a   Khvorova, Anastasia ^a  

^a Dharmacon Inc   (United States)

Author keywords

Off target effects; RNAi; siRNA; Toxicity

Indexed keywords

SMALL INTERFERING RNA;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; HELA CELLS; HUMANS; MALE; PROSTATIC NEOPLASMS; RNA, NEOPLASM; RNA, SMALL INTERFERING;

EID: 33745608078     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.28106     Document Type: Article

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