Chemical modification of siRNAs to improve serum stability without loss of efficacy

Biochemical and Biophysical Research Communications

Volumn 342, Issue 3, 2006, Pages 919-927

  Choung, Sorim ^a   Kim, Young Joo ^b   Kim, Seonhoe ^a   Park, Han Oh ^a   Choi, Young Chul ^a  

^a Bioneer Corporation   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Chemical modification; siRNA; Stability; Survivin

Indexed keywords

MESSENGER RNA; PHOSPHOROTHIOIC ACID; PYRIMIDINE NUCLEOTIDE; SMALL INTERFERING RNA;

ARTICLE; CHEMICAL MODIFICATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE; RNA STABILITY;

BASE SEQUENCE; CELL SIZE; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PYRIMIDINES; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 33644620908     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.02.049     Document Type: Article

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