ATF6 as a transcription activator of the endoplasmic reticulum stress element: Thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

Molecular and Cellular Biology

Volumn 20, Issue 14, 2000, Pages 5096-5106

  Li, Ming qing ^a   Baumeister, Peter ^a   Roy, Binayak ^a   Phan, Trevor ^a   Foti, Dolly ^a   Luo, Shengzhan ^a   Lee, Amy S ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THAPSIGARGIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; PROTEIN PROCESSING; STRESS; TRANSCRIPTION REGULATION;

3T3 CELLS; ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CARRIER PROTEINS; CCAAT-ENHANCER-BINDING PROTEINS; COS CELLS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; ENZYME INHIBITORS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MOLECULAR CHAPERONES; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; RESPONSE ELEMENTS; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS; THAPSIGARGIN; TRANSCRIPTION FACTORS; YY1 TRANSCRIPTION FACTOR;

EID: 0033920261     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.14.5096-5106.2000     Document Type: Article

References (36)

1. Cao, X., Y. Zhou, and A. S. Lee. 1995. Requirement of tyrosine-and serine/ threonine kinases in the transcriptional activation of the mammalian grp78/ BiP promoter by thapsigargin. J. Biol. Chem. 270:494-502.
2. Dooley, K. A., S. Millinder, and T. F. Osborne. 1998. Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y. J. Biol. Chem. 273:1349-1356.
3. Foti, D. M., A. Welihinda, R. J. Kaufman, and A. S. Lee. 1999. Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1. J. Biol. Chem. 274:30402-30409.
4. Gazit, G., J. Lu, and A. S. Lee. 1999. De-regulation of GRP stress protein expression in human breast cancer cell lines. Breast Cancer Res. Treat. 54:135-146.
5. Hai, T. W., F. Liu, W. J. Coukos, and M. R. Green. 1989. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 3:2083-2090.
6. Haze, K., H. Yoshida, H. Yanagi, T. Yura, and K. Mori. 1999. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell 10:3787-3799.
7. Hofmann, K., and W. Stoffel. 1993. TMbase - a database of membrane spanning proteins segments. Biol. Chem. Hoppe-Seyler 347:166.
8. Jackson, S. M., J. Ericsson, R Mantovani, and P. A. Edwards. 1998. Synergistic activation of transcription by nuclear factor Y and sterol regulatory element binding protein. J. Lipid Res. 39:1712-1721.
9. Kaufman, R. J. 1999. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13:1211-1233.
10. Kozutsumi, Y., M. Segal, K. Normington, M. J. Gething, and J. Sambrook. 1988. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332:462-464.
11. Lee, A. S. 1987. Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells. Trends Biochem. Sci. 12:20-23.
12. Lee, A. S. 1992. Mammalian stress response: induction of the glucose-regulated protein family. Curr. Opin. Cell Biol. 4:267-273.
13. 2+-ATPase inhibitor thapsigargin. J. Biol. Chem. 268:12003-12009.
14. Li, W. W., Y. Hsiung, V. Wong, K. Galvin, Y. Zhou, Y. Shi, and A. S. Lee. 1997. Suppression of grp78 core promoter element-mediated stress induction by the dbpA and dbpB (YB-1) cold shock domain proteins. Mol. Cell. Biol. 17:61-68.
15. 2+ depletion and formation of aberrant proteins: activation of the conserved stress-inducible grp core promoter element by the human nuclear factor YY1. Mol. Cell. Biol. 17:54-60.
16. Li, W. W., L. Sistonen, R. I. Morimoto, and A. S. Lee. 1994. Stress induction of the mammalian GRP78/BiP protein gene: in vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element. Mol. Cell. Biol. 14:5533-5546.
17. Maity, S. N., and B. de Crombrugghe. 1998. Role of the CCAAT-binding protein CBF/NF-Y in transcription. Trends Biochem. Sci. 23:174-178.
18. Mantovani, R., X. Y. Li, U. Pessara, R. Hooft van Huisjduijnen, C. Benoist, and D. Mathis. 1994. Dominant negative analogs of NF-YA. J. Biol. Chem. 269:20340-20346.
19. 2+-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis. J. Biol. Chem. 274:28476-28483.
20. Roy, B., and A. S. Lee. 1999. The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex. Nucleic Acids Res. 27:1437-1443.
21. Roy, B., W. W. Li, and A. S. Lee. 1996. Calcium-sensitive transcriptional activation of the proximal CCAAT regulatory element of the grp78/BiP promoter by the human nuclear factor CBF/NF-Y. J. Biol. Chem. 271: 28995-29002.
22. Shapiro, D. J., P. A. Sharp, W. W. Wahli, and M. J. Keller. 1988. A high-efficiency HeLa cell nuclear transcription extract. DNA 7:47-55.
23. Shi, Y., J.-S. Lee, and K. M. Galvin. 1997. Everything you have ever wanted to know about Yin Yang 1 .... Biochim. Biophys. Acta 1332:F49-F66.
24. Shi, Y., E. Seto, L. S. Chang, and T. Shenk. 1991. Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67:377-388.
25. Thuerauf, D. J., N. D. Arnold, D. Zechner, D. S. Hanford, K. M. DeMartin, P. M. McDonough, R. Prywes, and C. C. Glembotski. 1998. p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. J. Biol. Chem. 273:20636-20643.
26. Tirasophon, W., A. A. Welihinda, and R. J. Kaufman. 1998. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (IreIp) in mammalian cells. Genes Dev. 12:1812-1824.
27. Wang, X., R. Sato, M. S. Brown, X. Hua, and J. L. Goldstein. 1994. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77:53-62.
28. Wang, X. Z., H. P. Harding, Y. Zhang, E. M. Jolicoeur, M. Kuroda, and D. Ron. 1998. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 17:5708-5717.
29. Wooden, S. K., L. J. Li, D. Navarro, I. Qadri, L. Pereira, and A. S. Lee. 1991. Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTR/NF-I. Mol. Cell. Biol. 11:5612-5623.
30. Worgall, T. S., S. L. Sturley, T. Seo, T. F. Osborne, and R. J. Deckelbaum. 1998. Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein. J. Biol. Chem. 273:25537-25540.
31. 1/S control element of the hamster histone H3.2 promoter. Nucleic Acids Res. 26:4837-4845.
32. Yang, W., and S. Desiderio. 1997. BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. Proc. Natl. Acad. Sci. USA 94:604-609.
33. Yoshida, H., K. Haze, H. Yanagi, T. Yura, and K. Mori. 1998. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J. Biol. Chem. 273: 33741-33749.
34. Zhou, Q., R. W. Gedrich, and D. A. Engel. 1995. Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/ CREB. J. Virol. 69:4323-4330.
35. Zhou, Y., and A. S. Lee. 1998. Mechanism for the suppression of the mammalian stress response by genistein, an anticancer phytoestrogen from soy. J. Natl. Cancer Inst. 90:381-388.
36. Zhu, C., F. E. Johansen, and R. Prywes. 1997 Interaction of ATF6 and serum response factor. Mol. Cell. Biol. 17:4957-4966.