Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-α and interleukin-6: Model of NF-κB- and map kinase-dependent inflammation in advanced atherosclerosis

Journal of Biological Chemistry

Volumn 280, Issue 23, 2005, Pages 21763-21772

  Li, Yankun ^a   Schwabe, Robert F ^a   DeVries Seimon, Tracie ^a   Yao, Pin Mei ^a   Gerbod Giannone, Marie Christine ^a   Tall, Alan R ^a   Davis, Roger J ^b   Flavell, Richard ^c   Brenner, David A ^a   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ESTERIFICATION; IMMUNOLOGY; MATHEMATICAL MODELS; PRECIPITATION (CHEMICAL); PROTEINS; TUMORS;

CYTOKINES; INDUCTION; INFLAMMATORY MEDIATORS; MACROPHAGES;

CHOLESTEROL;

CHOLESTEROL; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FEMALE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ARTERIOSCLEROSIS; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CHOLESTEROL; CYTOKINES; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOBLOTTING; INFLAMMATION; INTERLEUKIN-6; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN FOLDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 20444461628     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501759200     Document Type: Article

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