Reactive oxygen species have a causal role in multiple forms of insulin resistance

Nature

Volumn 440, Issue 7086, 2006, Pages 944-948

  Houstis, Nicholas ^a,b,c   Rosen, Evan D ^a,d   Lander, Eric S ^a,b,c,e  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLOGY; CELLS; GENETIC ENGINEERING; INSULIN; MOLECULAR BIOLOGY; OXYGEN; PHYSIOLOGICAL MODELS;

CELLULAR REDOX STATES; DIABETES; GLUCOCORTICOID DEXAMETHASONE; INSULIN RESISTANCE; REACTIVE OXYGEN SPECIES (ROS);

BIODIVERSITY;

ACETYLCYSTEINE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCATALASE; CYTOKINE; DEXAMETHASONE; GLUCOCORTICOID; MANGANESE SUPEROXIDE DISMUTASE; MANGANESE TETRAKIS (4 BENZOIC ACID)PORPHYRIN; MITOCATALASE; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; RETROVIRUS VECTOR; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

GENE EXPRESSION; GENOMICS; GLUCOSE; HORMONE; OXYGEN; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSDUCTION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION STATE; PATHOGENESIS; PRIORITY JOURNAL; PROADIPOCYTE; TRANSGENE;

EID: 33645860825     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04634     Document Type: Article

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