-
1
-
-
0027164671
-
Transcription and translation of inducible nitric oxide synthase in pancreas of prediabetic BB rats
-
Kleemann R, Rothe H, Kolb-Bachofen V, Xie Q-W, Nathan C, Martin S, Kolb H (1993) Transcription and translation of inducible nitric oxide synthase in pancreas of prediabetic BB rats. FEBS Lett 328:9-12
-
(1993)
FEBS Lett
, vol.328
, pp. 9-12
-
-
Kleemann, R.1
Rothe, H.2
Kolb-Bachofen, V.3
Xie, Q.-W.4
Nathan, C.5
Martin, S.6
Kolb, H.7
-
2
-
-
0031032399
-
In vivo and in vitro evidence of altered nitric oxide metabolism in the spontaneously diabetic, insulin-dependent BB/Edinburgh rat
-
Lindsay RM, Peet RS, Wilkie GS, Rossiter SP, Smith W, Baird JD, Williams BC (1997) In vivo and in vitro evidence of altered nitric oxide metabolism in the spontaneously diabetic, insulin-dependent BB/Edinburgh rat. Br J Pharmacol 120:1-6
-
(1997)
Br J Pharmacol
, vol.120
, pp. 1-6
-
-
Lindsay, R.M.1
Peet, R.S.2
Wilkie, G.S.3
Rossiter, S.P.4
Smith, W.5
Baird, J.D.6
Williams, B.C.7
-
3
-
-
0030987135
-
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet β-cells
-
Suarez-Pinzon WL, Szabó C, Rabinovitch A (1997) Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet β-cells. Diabetes 46:907-911
-
(1997)
Diabetes
, vol.46
, pp. 907-911
-
-
Suarez-Pinzon, W.L.1
Szabó, C.2
Rabinovitch, A.3
-
4
-
-
0025197945
-
Cytokines and free radicals as effector molecules in the destruction of pancreatic β cells
-
Baekkeskov S, Hansen B (eds). Springer, Berlin Heidelberg New York
-
Mandrup-Poulsen T, Helqvist S, Wogensen LD, Molvig J, Pociot F, Johannesen J, Nerup J (1990) Cytokines and free radicals as effector molecules in the destruction of pancreatic β cells. In: Baekkeskov S, Hansen B (eds) Human diabetes - genetic, environmental and autoimmune etiology. Springer, Berlin Heidelberg New York, pp 166-193
-
(1990)
Human Diabetes - Genetic, Environmental and Autoimmune Etiology
, pp. 166-193
-
-
Mandrup-Poulsen, T.1
Helqvist, S.2
Wogensen, L.D.3
Molvig, J.4
Pociot, F.5
Johannesen, J.6
Nerup, J.7
-
5
-
-
0030890588
-
Cell death mediators in autoimmune diabetes - No shortage of suspects
-
Benoist C, Mathis D (1997) Cell death mediators in autoimmune diabetes - no shortage of suspects. Cell 89:1-3
-
(1997)
Cell
, vol.89
, pp. 1-3
-
-
Benoist, C.1
Mathis, D.2
-
6
-
-
0031667779
-
Apoptosis and the pathogenesis of IDDM. A question of life and death
-
Mauricio D, Mandrup-Poulsen T (1998) Apoptosis and the pathogenesis of IDDM. A question of life and death. Diabetes 47:1537-1543
-
(1998)
Diabetes
, vol.47
, pp. 1537-1543
-
-
Mauricio, D.1
Mandrup-Poulsen, T.2
-
7
-
-
0035668779
-
A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T (2001) A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 44:2115-2133
-
(2001)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
8
-
-
0019852821
-
CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse
-
Grankvist K, Marklund SL, Täljedal I-B (1981) CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochem J 199:393-398
-
(1981)
Biochem J
, vol.199
, pp. 393-398
-
-
Grankvist, K.1
Marklund, S.L.2
Täljedal, I.-B.3
-
9
-
-
0029984682
-
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
-
Lenzen S, Drinkgern J, Tiedge M (1996) Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 20:463-466
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 463-466
-
-
Lenzen, S.1
Drinkgern, J.2
Tiedge, M.3
-
10
-
-
0030689041
-
Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells
-
Tiedge M, Lortz S, Drinkgern J, Lenzen S (1997) Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes 46:1733-1742
-
(1997)
Diabetes
, vol.46
, pp. 1733-1742
-
-
Tiedge, M.1
Lortz, S.2
Drinkgern, J.3
Lenzen, S.4
-
11
-
-
0036061614
-
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone
-
Piganelli JD, Flores SC, Cruz C, Koepp J, Batinic-Haberle I, Crapo J, Day B, Kachadourian R, Young R, Bradley B, Haskins K (2002) A metalloporphyrin- based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. Diabetes 51:347-355
-
(2002)
Diabetes
, vol.51
, pp. 347-355
-
-
Piganelli, J.D.1
Flores, S.C.2
Cruz, C.3
Koepp, J.4
Batinic-Haberle, I.5
Crapo, J.6
Day, B.7
Kachadourian, R.8
Young, R.9
Bradley, B.10
Haskins, K.11
-
12
-
-
0036821898
-
Part I: Pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: Studies with FP15, a novel potent peroxynitrite decomposition catalyst
-
Szabo C, Mabley JG, Moeller SM, Shimanovich R, Pacher P, Virag L, Soriano FG, Van Duzer JH, Williams W, Salzman AL, Groves JT (2002) Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst. Mol Med 8:571-580
-
(2002)
Mol Med
, vol.8
, pp. 571-580
-
-
Szabo, C.1
Mabley, J.G.2
Moeller, S.M.3
Shimanovich, R.4
Pacher, P.5
Virag, L.6
Soriano, F.G.7
Van Duzer, J.H.8
Williams, W.9
Salzman, A.L.10
Groves, J.T.11
-
13
-
-
0028836705
-
Pancreatic antioxidant enzyme activity in normoglycemic diabetic prone BB rats
-
Roza AM, Pieper GM, Johnson CP, Adams MB (1995) Pancreatic antioxidant enzyme activity in normoglycemic diabetic prone BB rats. Pancreas 10:53-58
-
(1995)
Pancreas
, vol.10
, pp. 53-58
-
-
Roza, A.M.1
Pieper, G.M.2
Johnson, C.P.3
Adams, M.B.4
-
14
-
-
0023775296
-
Superoxide dismutase activity in the BB rat: A dynamic time-course study
-
Pisanti FA, Frascatore S, Papaccio G (1988) Superoxide dismutase activity in the BB rat: a dynamic time-course study. Life Sci 43:1625-1632
-
(1988)
Life Sci
, vol.43
, pp. 1625-1632
-
-
Pisanti, F.A.1
Frascatore, S.2
Papaccio, G.3
-
15
-
-
0028090026
-
Changes in pancreatic glutathione peroxidase and superoxide dismutase activities in the prediabetic diabetes-prone BB rat
-
L'Abbé MR, Trick KD (1994) Changes in pancreatic glutathione peroxidase and superoxide dismutase activities in the prediabetic diabetes-prone BB rat. Proc Soc Exp Biol Med 207:206-212
-
(1994)
Proc Soc Exp Biol Med
, vol.207
, pp. 206-212
-
-
L'Abbé, M.R.1
Trick, K.D.2
-
16
-
-
0023905774
-
Alterations in tissue antioxidant systems in the spontaneously diabetic (BB Wistar) rat
-
Wohaieb SA, Godin DV (1987) Alterations in tissue antioxidant systems in the spontaneously diabetic (BB Wistar) rat. Can J Physiol Pharmacol 65:2191-2195
-
(1987)
Can J Physiol Pharmacol
, vol.65
, pp. 2191-2195
-
-
Wohaieb, S.A.1
Godin, D.V.2
-
17
-
-
0026633029
-
Interleukin-1β increases the activity of superoxide dismutase in rat pancreatic islets
-
Borg LAH, Cagliero E, Sandler S, Welsh N, Eizirik DL (1992) Interleukin-1β increases the activity of superoxide dismutase in rat pancreatic islets. Endocrinology 130:2851-2857
-
(1992)
Endocrinology
, vol.130
, pp. 2851-2857
-
-
Borg, L.A.H.1
Cagliero, E.2
Sandler, S.3
Welsh, N.4
Eizirik, D.L.5
-
18
-
-
0029132167
-
Reversible binding and inhibition of catalase by nitric oxide
-
Brown GC (1995) Reversible binding and inhibition of catalase by nitric oxide. Eur J Biochem 232:188-191
-
(1995)
Eur J Biochem
, vol.232
, pp. 188-191
-
-
Brown, G.C.1
-
19
-
-
0346728620
-
Cytokines and nitric oxide inhibit enzyme activity of catalase but not its protein or mRNA expression in insulin-producing cells
-
Sigfrid LA, Cunningham JM, Beeharry N, Lortz S, Tiedge M, Lenzen S, Carlsson C, Green IC (2003) Cytokines and nitric oxide inhibit enzyme activity of catalase but not its protein or mRNA expression in insulin-producing cells. J Mol Endocrinol 31:509-518
-
(2003)
J Mol Endocrinol
, vol.31
, pp. 509-518
-
-
Sigfrid, L.A.1
Cunningham, J.M.2
Beeharry, N.3
Lortz, S.4
Tiedge, M.5
Lenzen, S.6
Carlsson, C.7
Green, I.C.8
-
20
-
-
0028956376
-
Nitric oxide synthesis and the effect of aminoguanidine and N-G-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat
-
Wu G (1995) Nitric oxide synthesis and the effect of aminoguanidine and N-G-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat. Diabetes 44:360-364
-
(1995)
Diabetes
, vol.44
, pp. 360-364
-
-
Wu, G.1
-
21
-
-
0025685395
-
Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-α via anL-arginine-dependent nitric oxide generating mechanism
-
Southern C, Schulster D, Green IC (1990) Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-α via anL-arginine-dependent nitric oxide generating mechanism. FEBS Lett 276:42-44
-
(1990)
FEBS Lett
, vol.276
, pp. 42-44
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
22
-
-
0028283283
-
The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting lines HIT-T15 and RINm5F
-
Cunningham JM, Mabley JG, Delaney CA, Green IC (1994) The effect of nitric oxide donors on insulin secretion, cyclic GMP and cyclic AMP in rat islets of Langerhans and the insulin-secreting lines HIT-T15 and RINm5F. Mol Cell Endocrinol 102:23-29
-
(1994)
Mol Cell Endocrinol
, vol.102
, pp. 23-29
-
-
Cunningham, J.M.1
Mabley, J.G.2
Delaney, C.A.3
Green, I.C.4
-
23
-
-
0027428461
-
Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
-
Delaney CA, Green MHL, Lowe JE, Green IC (1993) Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Lett 333:291-295
-
(1993)
FEBS Lett
, vol.333
, pp. 291-295
-
-
Delaney, C.A.1
Green, M.H.L.2
Lowe, J.E.3
Green, I.C.4
-
24
-
-
0032434935
-
Insulin secretion, DNA damage and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite and cytokines
-
Hadjivassiliou V, Green MHL, James RFL, Swift SM, Clayton HA, Green IC (1998) Insulin secretion, DNA damage and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite and cytokines. Nitric Oxide 2:429-441
-
(1998)
Nitric Oxide
, vol.2
, pp. 429-441
-
-
Hadjivassiliou, V.1
Green, M.H.L.2
James, R.F.L.3
Swift, S.M.4
Clayton, H.A.5
Green, I.C.6
-
25
-
-
0029814868
-
Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells
-
Packer L (ed). Academic, New York
-
Green MHL, Lowe JE, Delaney CA, Green IC (1996) Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells. In: Packer L (ed) Methods in Enzymology (Nitric Oxide). Academic, New York pp 243-267
-
(1996)
Methods in Enzymology (Nitric Oxide)
, pp. 243-267
-
-
Green, M.H.L.1
Lowe, J.E.2
Delaney, C.A.3
Green, I.C.4
-
26
-
-
0033047574
-
Insulitis and mechanisms of disease resistance: Studies in an animal model of insulin dependent diabetes mellitus
-
Bone AJ, Hitchcock PR, Gwilliam DJ, Cunningham JM, Barley J (1999) Insulitis and mechanisms of disease resistance: studies in an animal model of insulin dependent diabetes mellitus. J Mol Med 77:57-61
-
(1999)
J Mol Med
, vol.77
, pp. 57-61
-
-
Bone, A.J.1
Hitchcock, P.R.2
Gwilliam, D.J.3
Cunningham, J.M.4
Barley, J.5
-
27
-
-
0035079823
-
Apoptosis and disease progression in the spontaneously diabetic BB/S rat
-
Lally FJ, Ratcliff H, Bone AJ (2001) Apoptosis and disease progression in the spontaneously diabetic BB/S rat. Diabetologia 44:320-324
-
(2001)
Diabetologia
, vol.44
, pp. 320-324
-
-
Lally, F.J.1
Ratcliff, H.2
Bone, A.J.3
-
29
-
-
0033821419
-
Immunomagnetic purification of beta cells from rat islets of Langerhans
-
Hadjivassiliou V, Green MHL, Green IC (2000) Immunomagnetic purification of beta cells from rat islets of Langerhans. Diabetologia 43:1170-1177
-
(2000)
Diabetologia
, vol.43
, pp. 1170-1177
-
-
Hadjivassiliou, V.1
Green, M.H.L.2
Green, I.C.3
-
30
-
-
0009611219
-
Continuous, clonal insulin-and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor
-
Gazdar AF, Chick WL, Oie HK, Sims HL, King DL, Weir GC, Lauris V (1980) Continuous, clonal insulin-and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. Proc Natl Acad Sci USA 77:3519-3523
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 3519-3523
-
-
Gazdar, A.F.1
Chick, W.L.2
Oie, H.K.3
Sims, H.L.4
King, D.L.5
Weir, G.C.6
Lauris, V.7
-
32
-
-
0036179356
-
Nicotine reduces the incidence of type I diabetes in mice
-
Mabley JG, Pacher P, Southan GJ, Salzman AL, Szabo C (2002) Nicotine reduces the incidence of type I diabetes in mice. J Pharmacol Exp Ther 300:876-881
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 876-881
-
-
Mabley, J.G.1
Pacher, P.2
Southan, G.J.3
Salzman, A.L.4
Szabo, C.5
-
33
-
-
0023692586
-
A spectrophotometric method for determination of catalase activity in small tissue samples
-
Johansson LH, Borg LAH (1988) A spectrophotometric method for determination of catalase activity in small tissue samples. Anal Biochem 174:331-336
-
(1988)
Anal Biochem
, vol.174
, pp. 331-336
-
-
Johansson, L.H.1
Borg, L.A.H.2
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
0016155747
-
Iron containing superoxide dismutases from luminous bacteria
-
Puget K, Michelson AM (1974) Iron containing superoxide dismutases from luminous bacteria. Biochimie 56:1255-1267
-
(1974)
Biochimie
, vol.56
, pp. 1255-1267
-
-
Puget, K.1
Michelson, A.M.2
-
36
-
-
0019835246
-
Luminol assay for superoxide dismutase
-
Bensinger RE, Johnson CM (1981) Luminol assay for superoxide dismutase. Anal Biochem 116:142-145
-
(1981)
Anal Biochem
, vol.116
, pp. 142-145
-
-
Bensinger, R.E.1
Johnson, C.M.2
-
37
-
-
0014691242
-
Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
-
McCord JM, Fridovich I (1969) Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244:6049-6055
-
(1969)
J Biol Chem
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
38
-
-
0030730904
-
Insulin-like growth factor 1 reverses interleukin-1β inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans
-
Mabley JG, Belin VD, John NE, Green IC (1997) Insulin-like growth factor 1 reverses interleukin-1β inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans. FEBS Lett 417:235-238
-
(1997)
FEBS Lett
, vol.417
, pp. 235-238
-
-
Mabley, J.G.1
Belin, V.D.2
John, N.E.3
Green, I.C.4
-
39
-
-
0023919963
-
A simple technique for quantitation of low levels of DNA damage in individual cells
-
Singh NP, McCoy MT, Tice RR, Schneider EL (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191
-
(1988)
Exp Cell Res
, vol.175
, pp. 184-191
-
-
Singh, N.P.1
McCoy, M.T.2
Tice, R.R.3
Schneider, E.L.4
-
40
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction
-
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal Biochem 162:1560159
-
(1987)
Anal Biochem
, vol.162
, pp. 1560159
-
-
Chomczynski, P.1
Sacchi, N.2
-
42
-
-
0027468539
-
Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: A comparative study
-
Cornelius JG, Luttge BG, Peck AB (1993) Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: a comparative study. Free Radic Biol Med 14:409-420
-
(1993)
Free Radic Biol Med
, vol.14
, pp. 409-420
-
-
Cornelius, J.G.1
Luttge, B.G.2
Peck, A.B.3
-
43
-
-
0005167829
-
Investigations of diabetes-prone normoglycemic BB-rats
-
Shafrir E (ed). Smith-Gordon, London
-
Hahn HJ, Lucke S, Kuttler B, Dunger A, Volk HD, Diamantstein T (1990) Investigations of diabetes-prone normoglycemic BB-rats. In: Shafrir E (ed) Frontiers in diabetes research. Lessons from animal diabetes III. Smith-Gordon, London, pp 30-33
-
(1990)
Frontiers in Diabetes Research. Lessons from Animal Diabetes III
, pp. 30-33
-
-
Hahn, H.J.1
Lucke, S.2
Kuttler, B.3
Dunger, A.4
Volk, H.D.5
Diamantstein, T.6
-
44
-
-
0026321432
-
Prospective investigations of long-term normoglycaemic BB/OK-rats: Serial determination of glucose intolerance, insulitis, B-cell volume density and pancreatic insulin content
-
Hahn HJ, Lucke S, Klöting I, Besch W (1991) Prospective investigations of long-term normoglycaemic BB/OK-rats: serial determination of glucose intolerance, insulitis, B-cell volume density and pancreatic insulin content. Exp Clin Endocrinol 98:185-192
-
(1991)
Exp Clin Endocrinol
, vol.98
, pp. 185-192
-
-
Hahn, H.J.1
Lucke, S.2
Klöting, I.3
Besch, W.4
-
45
-
-
0027268225
-
Pancreatic islet function in nondiabetic and diabetic BB rats
-
Teruya M, Takei S, Forrest LE, Grunewald A, Chan EK, Charles MA (1993) Pancreatic islet function in nondiabetic and diabetic BB rats. Diabetes 42:1310-1317
-
(1993)
Diabetes
, vol.42
, pp. 1310-1317
-
-
Teruya, M.1
Takei, S.2
Forrest, L.E.3
Grunewald, A.4
Chan, E.K.5
Charles, M.A.6
-
46
-
-
0026668013
-
Insulin response of cultured islets from diabetic and nondiabetic BB rats
-
Curtis SB, Buchan AMJ, Pederson RA, Brown JC (1992) Insulin response of cultured islets from diabetic and nondiabetic BB rats. Metabolism 41:1047-1052
-
(1992)
Metabolism
, vol.41
, pp. 1047-1052
-
-
Curtis, S.B.1
Buchan, A.M.J.2
Pederson, R.A.3
Brown, J.C.4
-
47
-
-
0025945530
-
Insulin-secretion and islet endocrine cell content at onset and during the early stages of diabetes in the BB rat - Effect of the level of glycemic control
-
Pederson RA, Curtis SB, Chisholm CB, Gaba NRA, Campos RV, Brown JC (1991) Insulin-secretion and islet endocrine cell content at onset and during the early stages of diabetes in the BB rat - effect of the level of glycemic control. Can J Physiol Pharmacol 69:1230-1236
-
(1991)
Can J Physiol Pharmacol
, vol.69
, pp. 1230-1236
-
-
Pederson, R.A.1
Curtis, S.B.2
Chisholm, C.B.3
Gaba, N.R.A.4
Campos, R.V.5
Brown, J.C.6
-
48
-
-
0021470773
-
Somatostatin, glucagon and insulin secretion from perfused pancreas of BB rats
-
Ruggere MD, Patel YC (1984) Somatostatin, glucagon and insulin secretion from perfused pancreas of BB rats. Am J Physiol 247:E221-E227
-
(1984)
Am J Physiol
, vol.247
-
-
Ruggere, M.D.1
Patel, Y.C.2
-
50
-
-
0013592268
-
Phenotyping of cells infiltrating the pancreas of diabetic BB rats depending on duration of diabetes
-
Shafrir E (ed). Smith-Gordon, London
-
Lucke S, Liepe L, Todoran L, Besch W, Diamantstein T, Hahn H-J (1990) Phenotyping of cells infiltrating the pancreas of diabetic BB rats depending on duration of diabetes. In: Shafrir E (ed) Frontiers in diabetes research. Lessons from animal diabetes III. Smith-Gordon, London, pp 34-37
-
(1990)
Frontiers in Diabetes Research. Lessons from Animal Diabetes III
, pp. 34-37
-
-
Lucke, S.1
Liepe, L.2
Todoran, L.3
Besch, W.4
Diamantstein, T.5
Hahn, H.-J.6
-
51
-
-
0037603320
-
IL-1 beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction
-
Wachlin G, Augstein P, Schroder D, Kuttler B, Kloting I, Heinke P, Schmidt S (2003) IL-1 beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction. J Autoimmun 20:303-312
-
(2003)
J Autoimmun
, vol.20
, pp. 303-312
-
-
Wachlin, G.1
Augstein, P.2
Schroder, D.3
Kuttler, B.4
Kloting, I.5
Heinke, P.6
Schmidt, S.7
-
52
-
-
0024240862
-
Distinct macrophage subpopulations in pancreas of prediabetic BB/E rats
-
Walker R, Bone AJ, Cooke A, Baird JD (1988) Distinct macrophage subpopulations in pancreas of prediabetic BB/E rats. Diabetes 37:1301-1304
-
(1988)
Diabetes
, vol.37
, pp. 1301-1304
-
-
Walker, R.1
Bone, A.J.2
Cooke, A.3
Baird, J.D.4
-
53
-
-
0029582986
-
Toxic effects of superoxide, hydrogen peroxide and nitric oxide on human and pig islets
-
Jahr H, Bretzel RG, Wacker S, Weinand S, Brandhorst H, Brandhorst D, Lau D, Hering BJ, Federlin K (1995) Toxic effects of superoxide, hydrogen peroxide and nitric oxide on human and pig islets. Transplant Proc 27:3220-3221
-
(1995)
Transplant Proc
, vol.27
, pp. 3220-3221
-
-
Jahr, H.1
Bretzel, R.G.2
Wacker, S.3
Weinand, S.4
Brandhorst, H.5
Brandhorst, D.6
Lau, D.7
Hering, B.J.8
Federlin, K.9
-
54
-
-
0030030135
-
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM
-
Hussain MJ, Peakman M, Gallati S, Lo SSS, Hawa M, Viberti GC, Watkins PJ, Leslie RDG, Vergani D (1996) Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia 39:60-69
-
(1996)
Diabetologia
, vol.39
, pp. 60-69
-
-
Hussain, M.J.1
Peakman, M.2
Gallati, S.3
Lo, S.S.S.4
Hawa, M.5
Viberti, G.C.6
Watkins, P.J.7
Leslie, R.D.G.8
Vergani, D.9
-
55
-
-
0032523104
-
Cytokines and their roles in pancreatic islet β-cell destruction and insulin-dependent diabetes mellitus
-
Rabinovitch A, Suarez-Pinzon WL (1998) Cytokines and their roles in pancreatic islet β-cell destruction and insulin-dependent diabetes mellitus. Biochem Pharmacol 55:1139-1149
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1139-1149
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
56
-
-
0031850873
-
Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin-dependent diabetes mellitus
-
Sjöholm A (1998) Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin-dependent diabetes mellitus. Cell Death Differ 5:461-468
-
(1998)
Cell Death Differ
, vol.5
, pp. 461-468
-
-
Sjöholm, A.1
-
57
-
-
0029955383
-
Cytokine gene expression in the BE rat pancreas: Natural course and impact of bacterial vaccines
-
Kolb H, WorzPagenstert U, Kleemann R, Rothe H, Rowsell P, Scott FW (1996) Cytokine gene expression in the BE rat pancreas: Natural course and impact of bacterial vaccines. Diabetologia 39:1448-1454
-
(1996)
Diabetologia
, vol.39
, pp. 1448-1454
-
-
Kolb, H.1
WorzPagenstert, U.2
Kleemann, R.3
Rothe, H.4
Rowsell, P.5
Scott, F.W.6
-
58
-
-
0033869974
-
Islet protein expression changes during diabetes development in islet syngrafts in BB-DP rats and during rejection of BB-DP islet allografts
-
Christensen UB, Larsen PM, Fey SJ, Andersen HU, Nawrocki A, Sparre T, Mandrup-Poulsen T, Nerup J (2000) Islet protein expression changes during diabetes development in islet syngrafts in BB-DP rats and during rejection of BB-DP islet allografts. Autoimmunity 32:1-15
-
(2000)
Autoimmunity
, vol.32
, pp. 1-15
-
-
Christensen, U.B.1
Larsen, P.M.2
Fey, S.J.3
Andersen, H.U.4
Nawrocki, A.5
Sparre, T.6
Mandrup-Poulsen, T.7
Nerup, J.8
-
59
-
-
0030070207
-
Cytokine gene expression in islets and thyroids of BB rats: IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats
-
Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP, Rossini AA (1996) Cytokine gene expression in islets and thyroids of BB rats: IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. J Immunol 156:1315-1321
-
(1996)
J Immunol
, vol.156
, pp. 1315-1321
-
-
Zipris, D.1
Greiner, D.L.2
Malkani, S.3
Whalen, B.4
Mordes, J.P.5
Rossini, A.A.6
-
60
-
-
0029922661
-
Cytokine gene expression in pancreatic islet-infiltrating leukocytes of BB rats. Expression of Th1 cytokines correlates with β-cell destructive insulitis and IDDM
-
Rabinovitch A, Suarez-Pinzon W, El-Sheikh A, Sorensen O, Power RF (1996) Cytokine gene expression in pancreatic islet-infiltrating leukocytes of BB rats. Expression of Th1 cytokines correlates with β-cell destructive insulitis and IDDM. Diabetes 45:749-754
-
(1996)
Diabetes
, vol.45
, pp. 749-754
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.2
El-Sheikh, A.3
Sorensen, O.4
Power, R.F.5
-
61
-
-
0036435663
-
IL-1 beta induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis
-
Sparre T, Christensen UB, Larsen PM, Fey SJ, Wrzesinski K, Roepstorff P, Mandrup-Poulsen T, Pociot F, Karlsen AE, Nerup J (2002) IL-1 beta induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis. Diabetologia 45:1550-1561
-
(2002)
Diabetologia
, vol.45
, pp. 1550-1561
-
-
Sparre, T.1
Christensen, U.B.2
Larsen, P.M.3
Fey, S.J.4
Wrzesinski, K.5
Roepstorff, P.6
Mandrup-Poulsen, T.7
Pociot, F.8
Karlsen, A.E.9
Nerup, J.10
-
62
-
-
0037348563
-
Prophylactic insulin treatment of syngeneically transplanted pre-diabetic BB-DP rats
-
Sparre T, Sprinkel AME, Christensen UB, Karlsen AE, Pociot F, Nerup J (2003) Prophylactic insulin treatment of syngeneically transplanted pre-diabetic BB-DP rats. Autoimmunity 36:99-109
-
(2003)
Autoimmunity
, vol.36
, pp. 99-109
-
-
Sparre, T.1
Sprinkel, A.M.E.2
Christensen, U.B.3
Karlsen, A.E.4
Pociot, F.5
Nerup, J.6
-
63
-
-
0037315583
-
Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes
-
Bertera S, Crawford ML, Alexander AM, Papworth GD, Watkins SC, Robbins PD, Trucco M (2003) Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes. Diabetes 52:387-393
-
(2003)
Diabetes
, vol.52
, pp. 387-393
-
-
Bertera, S.1
Crawford, M.L.2
Alexander, A.M.3
Papworth, G.D.4
Watkins, S.C.5
Robbins, P.D.6
Trucco, M.7
-
64
-
-
0036628729
-
Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes
-
Sandstrom J, Jonsson LM, Edlund H, Holmberg D, Marklund SL (2002) Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes. Free Radic Biol Med 33:71-75
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 71-75
-
-
Sandstrom, J.1
Jonsson, L.M.2
Edlund, H.3
Holmberg, D.4
Marklund, S.L.5
-
65
-
-
0028203701
-
Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: Relation to nitric oxide production
-
Green IC, Cunningham JM, Delaney CA, Elphick MR, Mabley JG, Green MHL (1994) Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production. Biochem Soc Trans 22:30-37
-
(1994)
Biochem Soc Trans
, vol.22
, pp. 30-37
-
-
Green, I.C.1
Cunningham, J.M.2
Delaney, C.A.3
Elphick, M.R.4
Mabley, J.G.5
Green, M.H.L.6
-
66
-
-
0028626360
-
The inducible form of nitric oxide synthase (iNOS) in insulin-producing cells
-
Eizirik DL, Leijerstam F (1994) The inducible form of nitric oxide synthase (iNOS) in insulin-producing cells. Diabete Metab 20:116-122
-
(1994)
Diabete Metab
, vol.20
, pp. 116-122
-
-
Eizirik, D.L.1
Leijerstam, F.2
-
67
-
-
0020619943
-
Clinical forms and natural history of the diabetic syndrome, insulin and glucagon secretion in the BB rat
-
Marliss EB, Nakhooda AF, Poussier P (1983) Clinical forms and natural history of the diabetic syndrome, insulin and glucagon secretion in the BB rat. Metabolism 32:11-17
-
(1983)
Metabolism
, vol.32
, pp. 11-17
-
-
Marliss, E.B.1
Nakhooda, A.F.2
Poussier, P.3
-
68
-
-
0032899615
-
Nitric oxide metabolism and breakdown
-
Kelm M (1999) Nitric oxide metabolism and breakdown. Biochim Biopys Acta 1411:273-289
-
(1999)
Biochim Biopys Acta
, vol.1411
, pp. 273-289
-
-
Kelm, M.1
-
69
-
-
0029915909
-
Nitric oxide donors decrease the function and survival of human pancreatic islets
-
Eizirik DL, Delaney CA, Green MHL, Cunningham JM, Thorpe JR, Pipeleers DG, Hellerström C, Green IC (1996) Nitric oxide donors decrease the function and survival of human pancreatic islets. Mol Cell Endocrinol 118:71-83
-
(1996)
Mol Cell Endocrinol
, vol.118
, pp. 71-83
-
-
Eizirik, D.L.1
Delaney, C.A.2
Green, M.H.L.3
Cunningham, J.M.4
Thorpe, J.R.5
Pipeleers, D.G.6
Hellerström, C.7
Green, I.C.8
-
70
-
-
0028633557
-
Cytokines, nitric oxide and insulin secreting cells
-
Cunningham JM, Green IC (1994) Cytokines, nitric oxide and insulin secreting cells. Growth Regul 4:173-180
-
(1994)
Growth Regul
, vol.4
, pp. 173-180
-
-
Cunningham, J.M.1
Green, I.C.2
-
71
-
-
0031426764
-
Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM?
-
Eizirik DL, Pavlovic D (1997) Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM? Diabetes Metab Rev 13:293-307
-
(1997)
Diabetes Metab Rev
, vol.13
, pp. 293-307
-
-
Eizirik, D.L.1
Pavlovic, D.2
-
73
-
-
0029918676
-
The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistance/susceptibility
-
Farias-Eisner R, Chaudhuri G, Aeberhard E, Fukuto JM (1996) The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistance/susceptibility. J Biol Chem 271:6144-6151
-
(1996)
J Biol Chem
, vol.271
, pp. 6144-6151
-
-
Farias-Eisner, R.1
Chaudhuri, G.2
Aeberhard, E.3
Fukuto, J.M.4
-
74
-
-
0036667555
-
Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
-
Zelko IN, Mariani TJ, Folz RJ (2002) Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 33:337-349
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 337-349
-
-
Zelko, I.N.1
Mariani, T.J.2
Folz, R.J.3
-
75
-
-
0036380907
-
Response of anti-oxidant enzymes mRNA in the neonatal rat liver exposed to 1,2,3,4-tetrachlorodibenzo-p-dioxin via lactation
-
Kono Y, Okada S, Tazawa Y, Kanzaki S, Mura T, Ueta E, Nanba E, Otsuka Y (2002) Response of anti-oxidant enzymes mRNA in the neonatal rat liver exposed to 1,2,3,4-tetrachlorodibenzo-p-dioxin via lactation. Pediatr Int 44:481-487
-
(2002)
Pediatr Int
, vol.44
, pp. 481-487
-
-
Kono, Y.1
Okada, S.2
Tazawa, Y.3
Kanzaki, S.4
Mura, T.5
Ueta, E.6
Nanba, E.7
Otsuka, Y.8
-
77
-
-
0026510118
-
Cytotoxic effects of cytokines on rat islets: Evidence for involvement of free radicals and lipid peroxidation
-
Rabinovitch A, Suarez WL, Thomas PD, Strynadka K, Simpson I (1992) Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation. Diabetologia 35:409-413
-
(1992)
Diabetologia
, vol.35
, pp. 409-413
-
-
Rabinovitch, A.1
Suarez, W.L.2
Thomas, P.D.3
Strynadka, K.4
Simpson, I.5
-
78
-
-
0035029867
-
Identification of novel cytokine-induced genes in pancreatic β-cells by high-density oligonucleotide arrays
-
Cardozo AK, Kruhøffer M, Leeman R, Ørntoft T, Eizirik DL (2001) Identification of novel cytokine-induced genes in pancreatic β-cells by high-density oligonucleotide arrays. Diabetes 50:909-920
-
(2001)
Diabetes
, vol.50
, pp. 909-920
-
-
Cardozo, A.K.1
Kruhøffer, M.2
Leeman, R.3
Ørntoft, T.4
Eizirik, D.L.5
-
79
-
-
0034470113
-
Massive parallel gene expression profiling of RINm5F pancreatic islet beta-cells stimulated with interleukin-1 beta
-
Rieneck K, Bovin LF, Josefsen K, Buschard K, Svenson M, Bendtzen K (2000) Massive parallel gene expression profiling of RINm5F pancreatic islet beta-cells stimulated with interleukin-1 beta. APMIS 108:855-872
-
(2000)
APMIS
, vol.108
, pp. 855-872
-
-
Rieneck, K.1
Bovin, L.F.2
Josefsen, K.3
Buschard, K.4
Svenson, M.5
Bendtzen, K.6
-
80
-
-
0035966006
-
A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells
-
Cardozo AK, Heimberg H, Heremans Y, Leeman R, Kutlu B, Kruhoffer M, Orntoft T, Eizirik D (2001) A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells. J Biol Chem 276:48879-48886
-
(2001)
J Biol Chem
, vol.276
, pp. 48879-48886
-
-
Cardozo, A.K.1
Heimberg, H.2
Heremans, Y.3
Leeman, R.4
Kutlu, B.5
Kruhoffer, M.6
Orntoft, T.7
Eizirik, D.8
-
81
-
-
0033625664
-
Interleukin-1β-induced alteration in a β-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis
-
Ling Z, Van de Casteele M, Eizirik DL, Pipeleers DL (2000) Interleukin-1β-induced alteration in a β-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis. Diabetes 49:340-345
-
(2000)
Diabetes
, vol.49
, pp. 340-345
-
-
Ling, Z.1
Van De Casteele, M.2
Eizirik, D.L.3
Pipeleers, D.L.4
|