Double-stranded RNA-dependent protein kinase phosphorylation of the α-subunit of eukaryotic translation initiation factor 2 mediates apoptosis

Journal of Biological Chemistry

Volumn 281, Issue 30, 2006, Pages 21458-21468

  Scheuner, Donalyn ^a   Patel, Rupali ^a   Wang, Feng ^a   Lee, Kuei ^a   Kumar, Kotlo ^a,c   Wu, Jun ^a   Nilsson, Anders ^a   Karin, Michael ^b   Kaufman, Randal J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CYTOLOGY; ENZYMES; MOLECULAR BIOLOGY; RNA;

APOPTOSIS; EUKARYOTIC TRANSLATION INITIATION FACTOR; MOLECULAR SIGNALS; PHOSPHORYLATION;

ENZYME KINETICS;

CASPASE 3; INITIATION FACTOR 2; PROTEIN KINASE R; SERINE; TUMOR NECROSIS FACTOR ALPHA;

ALLELE; ALPHA CHAIN; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STIMULATION; CELL SURVIVAL; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EUKARYOTIC CELL; FIBROBLAST; GENE TARGETING; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; STRESS; TRANSLATION INITIATION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE; DNA; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; HELA CELLS; HOMOZYGOTE; HUMANS; MICE; PHOSPHORYLATION; RNA, DOUBLE-STRANDED; TRANSFECTION;

EUKARYOTA;

EID: 33746361817     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603784200     Document Type: Article

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