Tumor necrosis factor α (TNFα) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFα

Journal of Biological Chemistry

Volumn 280, Issue 40, 2005, Pages 33917-33925

  Xue, Xin ^a   Piao, Jiang Hu ^a   Nakajima, Akihito ^a   Sakon Komazawa, Sachiko ^a   Kojima, Yuko ^a   Mori, Kazutoshi ^b   Yagita, Hideo ^a   Okumura, Ko ^a   Harding, Heather ^c   Nakano, Hiroyasu ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; MOLECULAR BIOLOGY; OXIDATION; PROTEINS; REDUCTION; STRESSES;

ER STRESS; OXIDATIVE STRESS; PROTEIN RESPONSE; UNFOLDED PROTEIN RESPONSE (UPR);

TUMORS;

ARSENIC TRIOXIDE; GLUTATHIONE; HYDROGEN PEROXIDE; INITIATION FACTOR 2ALPHA; PROTEIN IRE1; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; TUNICAMYCIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FIBROSARCOMA; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; ARSENITES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DEATH; ENDOPLASMIC RETICULUM; FIBROSARCOMA; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; MICE; OXIDANTS; PROTEIN DENATURATION; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TERATOGENS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

MAMMALIA; MURINAE;

EID: 26644450729     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505818200     Document Type: Article

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