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Volumn 204, Issue , 2005, Pages 128-143

The B7/CD28 costimulatory family in autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; AUTOANTIGEN; B7 ANTIGEN; CD28 ANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 16244389649     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2005.00242.x     Document Type: Review
Times cited : (114)

References (138)
  • 3
    • 0033590502 scopus 로고    scopus 로고
    • ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
    • Hutloff A, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999;397:263-266.
    • (1999) Nature , vol.397 , pp. 263-266
    • Hutloff, A.1
  • 4
    • 0033212778 scopus 로고    scopus 로고
    • B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha
    • Swallow MM, Wallin JJ, Sha WC. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity 1999;11:423-432.
    • (1999) Immunity , vol.11 , pp. 423-432
    • Swallow, M.M.1    Wallin, J.J.2    Sha, W.C.3
  • 5
    • 0034651694 scopus 로고    scopus 로고
    • Cutting edge: Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
    • Ling V, et al. Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol 2000;164:1653-1657.
    • (2000) J Immunol , vol.164 , pp. 1653-1657
    • Ling, V.1
  • 6
    • 0033576707 scopus 로고    scopus 로고
    • T-cell co-stimulation through B7RP-1 and ICOS
    • Yoshinaga SK, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999;402:827-832.
    • (1999) Nature , vol.402 , pp. 827-832
    • Yoshinaga, S.K.1
  • 7
    • 0034704760 scopus 로고    scopus 로고
    • LICOS, a primordial costimulatory ligand?
    • Brodie D, et al. LICOS, a primordial costimulatory ligand? Curr Biol 2000;10:333-336.
    • (2000) Curr Biol , vol.10 , pp. 333-336
    • Brodie, D.1
  • 8
    • 0034667688 scopus 로고    scopus 로고
    • Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS
    • Wang S, et al. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood 2000;96:2808-2813.
    • (2000) Blood , vol.96 , pp. 2808-2813
    • Wang, S.1
  • 9
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992;11:3887-3895.
    • (1992) EMBO J , vol.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 10
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • Freeman GJ, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-1034.
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1
  • 11
    • 5844264920 scopus 로고    scopus 로고
    • PD-L2 is a second ligand for PD-1 and inhibits T cell activation
    • Latchman Y, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001;2:261-268.
    • (2001) Nat Immunol , vol.2 , pp. 261-268
    • Latchman, Y.1
  • 12
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 1999;5:1365-1369.
    • (1999) Nat Med , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 13
    • 0035794314 scopus 로고    scopus 로고
    • B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
    • Tseng SY, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001;193:839-846.
    • (2001) J Exp Med , vol.193 , pp. 839-846
    • Tseng, S.Y.1
  • 14
    • 5844252552 scopus 로고    scopus 로고
    • B7-H3: A costimulatory molecule for T-cell activation and IFN-gamma production
    • Chapoval AI, et al. B7-H3: a costimulatory molecule for T-cell activation and IFN-gamma production. Nat Immunol 2001;2:269-274.
    • (2001) Nat Immunol , vol.2 , pp. 269-274
    • Chapoval, A.I.1
  • 15
    • 0038094524 scopus 로고    scopus 로고
    • B7-H4, a molecule of the B7 family, negatively regulates T cell immunity
    • Sica GL, et al. B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity 2003;18:849-861.
    • (2003) Immunity , vol.18 , pp. 849-861
    • Sica, G.L.1
  • 17
    • 0038433329 scopus 로고    scopus 로고
    • B7S1, a novel B7 family member that negatively regulates T cell activation
    • Prasad DV, Richards S, Mai XM, Dong C. B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity 2003;18:863-873.
    • (2003) Immunity , vol.18 , pp. 863-873
    • Prasad, D.V.1    Richards, S.2    Mai, X.M.3    Dong, C.4
  • 18
    • 0037810670 scopus 로고    scopus 로고
    • BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
    • Watanabe N, et al. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol 2003;4:670-679.
    • (2003) Nat Immunol , vol.4 , pp. 670-679
    • Watanabe, N.1
  • 19
    • 0028032963 scopus 로고
    • The tissue distribution of the B7-2 costimulator in mice: Abundant expression on dendritic cells in situ and during maturation in vitro
    • Inaba K, et al. The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med 1994;180:1849-1860.
    • (1994) J Exp Med , vol.180 , pp. 1849-1860
    • Inaba, K.1
  • 20
    • 0027937702 scopus 로고
    • Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
    • Peach RJ, et al. Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J Exp Med 1994;180:2049-2058.
    • (1994) J Exp Med , vol.180 , pp. 2049-2058
    • Peach, R.J.1
  • 21
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995;3:87-98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1
  • 22
    • 0030293443 scopus 로고    scopus 로고
    • CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation
    • Sperling AI, Auger JA, Ehst BD, Rulifson IC, Thompson CB, Bluestone JA. CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation. J Immunol 1996;157:3909-3917.
    • (1996) J Immunol , vol.157 , pp. 3909-3917
    • Sperling, A.I.1    Auger, J.A.2    Ehst, B.D.3    Rulifson, I.C.4    Thompson, C.B.5    Bluestone, J.A.6
  • 23
    • 0026061865 scopus 로고
    • Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
    • Fraser JD, Irving BA, Crabtree GR, Weiss A. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 1991;251:313-316.
    • (1991) Science , vol.251 , pp. 313-316
    • Fraser, J.D.1    Irving, B.A.2    Crabtree, G.R.3    Weiss, A.4
  • 24
    • 0024506159 scopus 로고
    • Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
    • Lindstein T, June CH, Ledbetter JA, Stella G, Thompson CB. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 1989;244:339-343.
    • (1989) Science , vol.244 , pp. 339-343
    • Lindstein, T.1    June, C.H.2    Ledbetter, J.A.3    Stella, G.4    Thompson, C.B.5
  • 25
    • 0033016465 scopus 로고    scopus 로고
    • CD28 induces cell cycle progression by IL-2-independent down-regulation of p27kip1 expression in human peripheral T lymphocytes
    • Boonen GJ, van Dijk AM, Verdonck LF, van Lier RA, Rijksen G, Medema RH. CD28 induces cell cycle progression by IL-2-independent down-regulation of p27kip1 expression in human peripheral T lymphocytes. Eur J Immunol 1999;29:789-798.
    • (1999) Eur J Immunol , vol.29 , pp. 789-798
    • Boonen, G.J.1    Van Dijk, A.M.2    Verdonck, L.F.3    Van Lier, R.A.4    Rijksen, G.5    Medema, R.H.6
  • 26
    • 0033976064 scopus 로고    scopus 로고
    • CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression
    • Appleman LJ, Berezovskaya A, Grass I, Boussiotis VA. CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression. J Immunol 2000;164:144-151.
    • (2000) J Immunol , vol.164 , pp. 144-151
    • Appleman, L.J.1    Berezovskaya, A.2    Grass, I.3    Boussiotis, V.A.4
  • 27
    • 0029845747 scopus 로고    scopus 로고
    • T cell responses are governed by avidity and co-stimulatory thresholds
    • Bachmann MF, et al. T cell responses are governed by avidity and co-stimulatory thresholds. Eur J Immunol 1996;16:2017-2022.
    • (1996) Eur J Immunol , vol.16 , pp. 2017-2022
    • Bachmann, M.F.1
  • 29
    • 0027281691 scopus 로고
    • Differential T cell costimulatory requirements in CD28-deficient mice
    • Shahinian A, et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993;261:609-612.
    • (1993) Science , vol.261 , pp. 609-612
    • Shahinian, A.1
  • 30
    • 0029031023 scopus 로고
    • Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response
    • Lucas PJ, Negishi I, Nakayama K, Fields LE, Loh DY. Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response. J Immunol 1995;154:5757-5768.
    • (1995) J Immunol , vol.154 , pp. 5757-5768
    • Lucas, P.J.1    Negishi, I.2    Nakayama, K.3    Fields, L.E.4    Loh, D.Y.5
  • 31
    • 0036172220 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength
    • Egen JG, Allison JP. Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity 2002;16:23-35.
    • (2002) Immunity , vol.16 , pp. 23-35
    • Egen, J.G.1    Allison, J.P.2
  • 32
    • 0033083788 scopus 로고    scopus 로고
    • Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases
    • Chuang E, et al. Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases. J Immunol 1999;162:1270-1277.
    • (1999) J Immunol , vol.162 , pp. 1270-1277
    • Chuang, E.1
  • 33
    • 0032545452 scopus 로고    scopus 로고
    • Molecular basis of T cell inactivation by CTLA-4
    • Lee KM, et al. Molecular basis of T cell inactivation by CTLA-4. Science 1998;282:2263-2266.
    • (1998) Science , vol.282 , pp. 2263-2266
    • Lee, K.M.1
  • 34
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas TL, Bakker CY, Bluestone JA. CTLA-4 ligation blocks CD28-dependent T cell activation. J Exp Med 1996;183:2541-2550.
    • (1996) J Exp Med , vol.183 , pp. 2541-2550
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 37
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995;3:541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 38
    • 0028791059 scopus 로고
    • Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
    • Waterhouse P, et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995;270:985-988.
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1
  • 40
    • 0034327808 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J Immunol 2000;165:5035-5040.
    • (2000) J Immunol , vol.165 , pp. 5035-5040
    • McAdam, A.J.1
  • 41
    • 0038545370 scopus 로고    scopus 로고
    • CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes
    • Parry RV, Rumbley CA, Vandenberghe LH, June CH, Riley JL. CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes. J Immunol 2003;171:166-174.
    • (2003) J Immunol , vol.171 , pp. 166-174
    • Parry, R.V.1    Rumbley, C.A.2    Vandenberghe, L.H.3    June, C.H.4    Riley, J.L.5
  • 42
    • 0037455064 scopus 로고    scopus 로고
    • A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)
    • Harada Y, et al. A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS). J Exp Med 2003;197:257-262.
    • (2003) J Exp Med , vol.197 , pp. 257-262
    • Harada, Y.1
  • 43
    • 0036604898 scopus 로고    scopus 로고
    • The right place at the right time: Novel B7 family members regulate effector T cell responses
    • Liang L, Sha WC. The right place at the right time: novel B7 family members regulate effector T cell responses. Curr Opin Immunol 2002;14:384-390.
    • (2002) Curr Opin Immunol , vol.14 , pp. 384-390
    • Liang, L.1    Sha, W.C.2
  • 44
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • Dong C, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101.
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1
  • 45
    • 0035804268 scopus 로고    scopus 로고
    • ICOS is critical for CD40-mediated antibody class switching
    • McAdam AJ, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001;409:102-105.
    • (2001) Nature , vol.409 , pp. 102-105
    • McAdam, A.J.1
  • 46
    • 0036740602 scopus 로고    scopus 로고
    • ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells
    • Witsch EJ, et al. ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells. Eur J Immunol 2002;32:2680-2686.
    • (2002) Eur J Immunol , vol.32 , pp. 2680-2686
    • Witsch, E.J.1
  • 47
    • 0037455003 scopus 로고    scopus 로고
    • + effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10
    • + effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10. J Exp Med 2003;197:181-193.
    • (2003) J Exp Med , vol.197 , pp. 181-193
    • Lohning, M.1
  • 48
    • 0034927194 scopus 로고    scopus 로고
    • PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
    • Nishimura H, Honjo T. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol 2001;22:265-268.
    • (2001) Trends Immunol , vol.22 , pp. 265-268
    • Nishimura, H.1    Honjo, T.2
  • 49
    • 0035340798 scopus 로고    scopus 로고
    • CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
    • Shlapatska LM, et al. CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. J Immunol 2001;166:5480-5487.
    • (2001) J Immunol , vol.166 , pp. 5480-5487
    • Shlapatska, L.M.1
  • 50
    • 0029964018 scopus 로고    scopus 로고
    • Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes
    • Nishimura H, et al. Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. Int Immunol 1996;8:773-780.
    • (1996) Int Immunol , vol.8 , pp. 773-780
    • Nishimura, H.1
  • 51
    • 0030005099 scopus 로고    scopus 로고
    • Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
    • Agata Y, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996;8:765-772.
    • (1996) Int Immunol , vol.8 , pp. 765-772
    • Agata, Y.1
  • 52
    • 3142688997 scopus 로고    scopus 로고
    • SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
    • Chemnitz JM, Parry RV, Nichols KE, June CH, Riley JL. SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol 2004;173:945-954.
    • (2004) J Immunol , vol.173 , pp. 945-954
    • Chemnitz, J.M.1    Parry, R.V.2    Nichols, K.E.3    June, C.H.4    Riley, J.L.5
  • 53
    • 0035846991 scopus 로고    scopus 로고
    • Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
    • Nishimura H, et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001;291:319-322.
    • (2001) Science , vol.291 , pp. 319-322
    • Nishimura, H.1
  • 54
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999;11:141-151.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 55
    • 0038185203 scopus 로고    scopus 로고
    • Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
    • Wang S, Bajorath J, Flies DB, Dong H, Honjo T, Chen L. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med 2003;197:1083-1091.
    • (2003) J Exp Med , vol.197 , pp. 1083-1091
    • Wang, S.1    Bajorath, J.2    Flies, D.B.3    Dong, H.4    Honjo, T.5    Chen, L.6
  • 56
    • 0038491416 scopus 로고    scopus 로고
    • + T cells independent of the PD-1 receptor
    • + T cells independent of the PD-1 receptor. J Exp Med 2003;198:31-38.
    • (2003) J Exp Med , vol.198 , pp. 31-38
    • Shin, T.1
  • 58
    • 0043123303 scopus 로고    scopus 로고
    • Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: Divergent history of functional redundancy and exon loss
    • Ling V, et al. Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Genomics 2003;82:365-377.
    • (2003) Genomics , vol.82 , pp. 365-377
    • Ling, V.1
  • 59
    • 0041381300 scopus 로고    scopus 로고
    • The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses
    • Suh WK, et al. The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol 2003;4:899-906.
    • (2003) Nat Immunol , vol.4 , pp. 899-906
    • Suh, W.K.1
  • 61
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the aire protein
    • Anderson MS, et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002;298:1395-1401.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1
  • 63
    • 0030993441 scopus 로고    scopus 로고
    • Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals
    • Cibotti R, Punt JA, Dash KS, Sharrow SO, Singer A. Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals. Immunity 1997;6:245-255.
    • (1997) Immunity , vol.6 , pp. 245-255
    • Cibotti, R.1    Punt, J.A.2    Dash, K.S.3    Sharrow, S.O.4    Singer, A.5
  • 64
    • 0035284806 scopus 로고    scopus 로고
    • Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation
    • McKean DJ, et al. Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation. J Immunol 2001;166:3468-3475.
    • (2001) J Immunol , vol.166 , pp. 3468-3475
    • McKean, D.J.1
  • 65
    • 0026649765 scopus 로고
    • Identification and distribution of the costimulatory receptor CD28 in the mouse
    • Gross JA, Callas E, Allison JP. Identification and distribution of the costimulatory receptor CD28 in the mouse. J Immunol 1992;149:380-388.
    • (1992) J Immunol , vol.149 , pp. 380-388
    • Gross, J.A.1    Callas, E.2    Allison, J.P.3
  • 66
    • 0034533085 scopus 로고    scopus 로고
    • Induction, binding specificity and function of human ICOS
    • Beier KC, et al. Induction, binding specificity and function of human ICOS. Eur J Immunol 2000;30:3707-3717.
    • (2000) Eur J Immunol , vol.30 , pp. 3707-3717
    • Beier, K.C.1
  • 67
    • 0032487574 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes
    • Cilio CM, Daws MR, Malashicheva A, Sentman CL, Holmberg D. Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes. J Exp Med 1998;188:1239-1246.
    • (1998) J Exp Med , vol.188 , pp. 1239-1246
    • Cilio, C.M.1    Daws, M.R.2    Malashicheva, A.3    Sentman, C.L.4    Holmberg, D.5
  • 68
    • 0028220663 scopus 로고
    • B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes
    • Degermann S, Surh CD, Glimcher LH, Sprent J, Lo D. B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes. J Immunol 1994;152:3254-3263.
    • (1994) J Immunol , vol.152 , pp. 3254-3263
    • Degermann, S.1    Surh, C.D.2    Glimcher, L.H.3    Sprent, J.4    Lo, D.5
  • 69
    • 0028136298 scopus 로고
    • The costimulatory molecule B7 is expressed in the medullary region of the murine thymus
    • Reiser H, Schneeberger EE. The costimulatory molecule B7 is expressed in the medullary region of the murine thymus. Immunology 1994;81:532-537.
    • (1994) Immunology , vol.81 , pp. 532-537
    • Reiser, H.1    Schneeberger, E.E.2
  • 70
    • 0242303572 scopus 로고    scopus 로고
    • Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses
    • Liang SC, et al. Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses. Eur J Immunol 2003;33:2706-2716.
    • (2003) Eur J Immunol , vol.33 , pp. 2706-2716
    • Liang, S.C.1
  • 73
    • 0030066656 scopus 로고    scopus 로고
    • CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance
    • Walunas TL, Sperling AI, Khattri R, Thompson CB, Bluestone JA. CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance. J Immunol 1996;156:1006-1013.
    • (1996) J Immunol , vol.156 , pp. 1006-1013
    • Walunas, T.L.1    Sperling, A.I.2    Khattri, R.3    Thompson, C.B.4    Bluestone, J.A.5
  • 75
    • 0027957577 scopus 로고
    • + diymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
    • + diymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J Exp Med 1994;179:709-713.
    • (1994) J Exp Med , vol.179 , pp. 709-713
    • Punt, J.A.1    Osborne, B.A.2    Takahama, Y.3    Sharrow, S.O.4    Singer, A.5
  • 76
    • 0037514517 scopus 로고    scopus 로고
    • A role for the B7-1/B7-2:CD28/CTLA-4 pathway during negative selection
    • Buhlmann JE, Elkin SK, Sharpe AH. A role for the B7-1/B7-2:CD28/CTLA-4 pathway during negative selection. J Immunol 2003;170:5421-5428.
    • (2003) J Immunol , vol.170 , pp. 5421-5428
    • Buhlmann, J.E.1    Elkin, S.K.2    Sharpe, A.H.3
  • 77
    • 0035873688 scopus 로고    scopus 로고
    • Requirement for a complex array of costimulators in the negative selection of autoreactive thymocytes in vivo
    • Li R, Page DM. Requirement for a complex array of costimulators in the negative selection of autoreactive thymocytes in vivo. J Immunol 2001;166:6050-6056.
    • (2001) J Immunol , vol.166 , pp. 6050-6056
    • Li, R.1    Page, D.M.2
  • 78
    • 0034610980 scopus 로고    scopus 로고
    • Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice
    • Nishimura H, Honjo T, Minato N. Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice. J Exp Med 2000;191:891-898.
    • (2000) J Exp Med , vol.191 , pp. 891-898
    • Nishimura, H.1    Honjo, T.2    Minato, N.3
  • 79
    • 0142149029 scopus 로고    scopus 로고
    • Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells
    • Blank C, Brown I, Marks R, Nishimura H, Honjo T, Gajewski TF. Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells. J Immunol 2003;171:4574-4581.
    • (2003) J Immunol , vol.171 , pp. 4574-4581
    • Blank, C.1    Brown, I.2    Marks, R.3    Nishimura, H.4    Honjo, T.5    Gajewski, T.F.6
  • 80
    • 0036219003 scopus 로고    scopus 로고
    • T cell response in experimental autoimmune encephalomyelitis (EAE): Role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire
    • Kuchroo VK, Anderson AC, Waldner H, Munder M, Bettelli E, Nicholson LB. T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire. Annu Rev Immunol 2002;20:101-123.
    • (2002) Annu Rev Immunol , vol.20 , pp. 101-123
    • Kuchroo, V.K.1    Anderson, A.C.2    Waldner, H.3    Munder, M.4    Bettelli, E.5    Nicholson, L.B.6
  • 81
    • 0037478632 scopus 로고    scopus 로고
    • + T cells in autoimmune diabetes
    • + T cells in autoimmune diabetes. Proc Natl Acad Sci USA 2003;100:8384-8388.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8384-8388
    • Lieberman, S.M.1
  • 82
    • 0037438615 scopus 로고    scopus 로고
    • Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers
    • Reddy J, et al. Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers. J Immunol 2003;170:870-877.
    • (2003) J Immunol , vol.170 , pp. 870-877
    • Reddy, J.1
  • 83
    • 1342303410 scopus 로고    scopus 로고
    • Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers
    • Bischof F, et al. Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers. J Immunol 2004;172:2878-2884.
    • (2004) J Immunol , vol.172 , pp. 2878-2884
    • Bischof, F.1
  • 84
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo VK, et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995;80:707-718.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1
  • 85
    • 0030175603 scopus 로고    scopus 로고
    • Role of Fas-mediated cell death in the regulation of immune responses
    • Van Parijs L, Abbas AK. Role of Fas-mediated cell death in the regulation of immune responses. Curr Opin Immunol 1996;8:355-361.
    • (1996) Curr Opin Immunol , vol.8 , pp. 355-361
    • Van Parijs, L.1    Abbas, A.K.2
  • 86
    • 0032843342 scopus 로고    scopus 로고
    • Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis
    • Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. J Exp Med 1999;190:733-740.
    • (1999) J Exp Med , vol.190 , pp. 733-740
    • Chang, T.T.1    Jabs, C.2    Sobel, R.A.3    Kuchroo, V.K.4    Sharpe, A.H.5
  • 87
    • 0042969045 scopus 로고    scopus 로고
    • Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/ B7-2-deficient mice
    • Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/ B7-2-deficient mice. Eur J Immunol 2003;33:2022-2032.
    • (2003) Eur J Immunol , vol.33 , pp. 2022-2032
    • Chang, T.T.1    Sobel, R.A.2    Wei, T.3    Ransohoff, R.M.4    Kuchroo, V.K.5    Sharpe, A.H.6
  • 88
    • 0242574700 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
    • Kremer JM, et al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med 2003;349:1907-1915.
    • (2003) N Engl J Med , vol.349 , pp. 1907-1915
    • Kremer, J.M.1
  • 89
    • 0034870102 scopus 로고    scopus 로고
    • ICOS ligand costimulation is required for T-cell encephalitogenicity
    • Sporici RA, et al. ICOS ligand costimulation is required for T-cell encephalitogenicity. Clin Immunol 2001;100:277-288.
    • (2001) Clin Immunol , vol.100 , pp. 277-288
    • Sporici, R.A.1
  • 90
    • 0034922160 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
    • Rottman JB, et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat Immunol 2001;2:605-611.
    • (2001) Nat Immunol , vol.2 , pp. 605-611
    • Rottman, J.B.1
  • 91
    • 0037477604 scopus 로고    scopus 로고
    • Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
    • Salama AD, et al. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med 2003;198:71-78.
    • (2003) J Exp Med , vol.198 , pp. 71-78
    • Salama, A.D.1
  • 92
    • 0242559053 scopus 로고    scopus 로고
    • + T cell activation and cytolysis
    • + T cell activation and cytolysis. Eur J Immunol 2003;33:3117-3126.
    • (2003) Eur J Immunol , vol.33 , pp. 3117-3126
    • Rodig, N.1
  • 93
    • 3242677686 scopus 로고    scopus 로고
    • PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
    • Latchman YE, et al. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proc Natl Acad Sci USA 2004;101:10691-10696.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10691-10696
    • Latchman, Y.E.1
  • 94
    • 2442461055 scopus 로고    scopus 로고
    • The roles of the new negative T cell costimulatory pathways in regulating autoimmunity
    • Khoury SJ, Sayegh MH. The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. Immunity 2004;20:529-538.
    • (2004) Immunity , vol.20 , pp. 529-538
    • Khoury, S.J.1    Sayegh, M.H.2
  • 95
    • 0035061536 scopus 로고    scopus 로고
    • Tolerance to islet autoantigens in type 1 diabetes
    • Bach JF, Chatenoud L. Tolerance to islet autoantigens in type 1 diabetes. Annu Rev Immunol 2001;19:131-161.
    • (2001) Annu Rev Immunol , vol.19 , pp. 131-161
    • Bach, J.F.1    Chatenoud, L.2
  • 96
    • 2642655282 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
    • Luhder F, Hoglund P, Allison JP, Benoist C, Mathis D. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J Exp Med 1998;187:427-432.
    • (1998) J Exp Med , vol.187 , pp. 427-432
    • Luhder, F.1    Hoglund, P.2    Allison, J.P.3    Benoist, C.4    Mathis, D.5
  • 97
    • 0034710983 scopus 로고    scopus 로고
    • Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
    • Luhder F, Chambers C, Allison JP, Benoist C, Mathis D. Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells. Proc Natl Acad Sci USA 2000;97:12204-12209.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12204-12209
    • Luhder, F.1    Chambers, C.2    Allison, J.P.3    Benoist, C.4    Mathis, D.5
  • 98
    • 3042592443 scopus 로고    scopus 로고
    • Cooperative roles of ctla-4 and regulatory T cells in tolerance to an islet cell antigen
    • Eggena MP, Walker LS, Nagabhushanam V, Barron L, Chodos A, Abbas AK. Cooperative roles of ctla-4 and regulatory T cells in tolerance to an islet cell antigen. J Exp Med 2004;199:1725-1730.
    • (2004) J Exp Med , vol.199 , pp. 1725-1730
    • Eggena, M.P.1    Walker, L.S.2    Nagabhushanam, V.3    Barron, L.4    Chodos, A.5    Abbas, A.K.6
  • 99
    • 2942692037 scopus 로고    scopus 로고
    • + T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • + T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med 2004;199:1479-1489.
    • (2004) J Exp Med , vol.199 , pp. 1479-1489
    • Herman, A.E.1    Freeman, G.J.2    Mathis, D.3    Benoist, C.4
  • 100
    • 0037477605 scopus 로고    scopus 로고
    • The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
    • Ansari MJ, et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 2003;198:63-69.
    • (2003) J Exp Med , vol.198 , pp. 63-69
    • Ansari, M.J.1
  • 101
    • 85047690551 scopus 로고    scopus 로고
    • Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection
    • Subudhi SK, et al. Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. J Clin Invest 2004;113:694-700.
    • (2004) J Clin Invest , vol.113 , pp. 694-700
    • Subudhi, S.K.1
  • 103
    • 0029905555 scopus 로고    scopus 로고
    • Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo
    • De Smedt T, et al. Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo. J Exp Med 1996;184:1413-1424.
    • (1996) J Exp Med , vol.184 , pp. 1413-1424
    • De Smedt, T.1
  • 104
    • 0141923690 scopus 로고    scopus 로고
    • Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
    • Sato S, et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 2003;171:4304-4310.
    • (2003) J Immunol , vol.171 , pp. 4304-4310
    • Sato, S.1
  • 105
    • 0036852170 scopus 로고    scopus 로고
    • CTLA-4-Ig regulates tryptophan catabolism in vivo
    • Grohmann U, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 2002;3:1097-1101.
    • (2002) Nat Immunol , vol.3 , pp. 1097-1101
    • Grohmann, U.1
  • 106
    • 0036884130 scopus 로고    scopus 로고
    • Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division
    • Lee GK, Park HJ, Macleod M, Chandler P, Munn DH, Mellor AL. Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division. Immunology 2002;107:452-460.
    • (2002) Immunology , vol.107 , pp. 452-460
    • Lee, G.K.1    Park, H.J.2    Macleod, M.3    Chandler, P.4    Munn, D.H.5    Mellor, A.L.6
  • 107
    • 0037111483 scopus 로고    scopus 로고
    • Expression of programmed death 1 ligands by murine T cells and APC
    • Yamazaki T, et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 2002;169:5538-5545.
    • (2002) J Immunol , vol.169 , pp. 5538-5545
    • Yamazaki, T.1
  • 108
    • 0037307930 scopus 로고    scopus 로고
    • Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
    • Brown JA, et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol 2003;170:1257-1266.
    • (2003) J Immunol , vol.170 , pp. 1257-1266
    • Brown, J.A.1
  • 109
    • 0037131988 scopus 로고    scopus 로고
    • Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells
    • Nguyen LT, et al. Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells. J Exp Med 2002;196:1393-1398.
    • (2002) J Exp Med , vol.196 , pp. 1393-1398
    • Nguyen, L.T.1
  • 110
    • 2942655175 scopus 로고    scopus 로고
    • 'Educated' dendritic cells act as messengers from memory to naive T helper cells
    • Alpan O, Bachelder E, Isil E, Arnheiter H, Matzinger P. 'Educated' dendritic cells act as messengers from memory to naive T helper cells. Nat Immunol 2004;5:615-622.
    • (2004) Nat Immunol , vol.5 , pp. 615-622
    • Alpan, O.1    Bachelder, E.2    Isil, E.3    Arnheiter, H.4    Matzinger, P.5
  • 111
    • 0033567051 scopus 로고    scopus 로고
    • B7.2(CD86) but not B7.1(CD80) costimulation is required for the induction of low dose oral tolerance
    • Liu L, Kuchroo VK, Weiner HL. B7.2(CD86) but not B7.1(CD80) costimulation is required for the induction of low dose oral tolerance. J Immunol 1999;163:2284-2290.
    • (1999) J Immunol , vol.163 , pp. 2284-2290
    • Liu, L.1    Kuchroo, V.K.2    Weiner, H.L.3
  • 113
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 1969;166:753-755.
    • (1969) Science , vol.166 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 114
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 115
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 118
    • 0141920662 scopus 로고    scopus 로고
    • + regulatory T cells
    • + regulatory T cells. J Immunol 2003;171:3348-3352.
    • (2003) J Immunol , vol.171 , pp. 3348-3352
    • Tang, Q.1
  • 119
    • 0035320679 scopus 로고    scopus 로고
    • + regulatory T cells induced by an agonist self-peptide
    • + regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-306.
    • (2001) Nat Immunol , vol.2 , pp. 301-306
    • Jordan, M.S.1
  • 120
    • 0033682056 scopus 로고    scopus 로고
    • + immunoregulatory T cells that control autoimmune diabetes
    • + immunoregulatory T cells that control autoimmune diabetes. Immunity 2000;12:431-440.
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 121
    • 0037810672 scopus 로고    scopus 로고
    • The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens
    • Lohr J, Knoechel B, Jiang S, Sharpe AH, Abbas AK. The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol 2003;4:664-669.
    • (2003) Nat Immunol , vol.4 , pp. 664-669
    • Lohr, J.1    Knoechel, B.2    Jiang, S.3    Sharpe, A.H.4    Abbas, A.K.5
  • 122
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302.
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 125
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, et al. Immunologic self-tolerance maintained by CD25(+) CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-310.
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1
  • 126
    • 0347994958 scopus 로고    scopus 로고
    • B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions
    • Taylor PA, Lees CJ, Fournier S, Allison JP, Sharpe AH, Blazar BR. B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions. J Immunol 2004;172:34-39.
    • (2004) J Immunol , vol.172 , pp. 34-39
    • Taylor, P.A.1    Lees, C.J.2    Fournier, S.3    Allison, J.P.4    Sharpe, A.H.5    Blazar, B.R.6
  • 127
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci USA 2004;101:10398-10403.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 128
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • Akbari O, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002;8:1024-1032.
    • (2002) Nat Med , vol.8 , pp. 1024-1032
    • Akbari, O.1
  • 129
    • 0038617545 scopus 로고    scopus 로고
    • The complex role of interleukin-10 in autoimmunity
    • Groux H, Cottrez F. The complex role of interleukin-10 in autoimmunity. J Autoimmun 2003;20:281-285.
    • (2003) J Autoimmun , vol.20 , pp. 281-285
    • Groux, H.1    Cottrez, F.2
  • 130
    • 2942642383 scopus 로고    scopus 로고
    • In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • Tang Q, et al. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 2004;199:1455-1465.
    • (2004) J Exp Med , vol.199 , pp. 1455-1465
    • Tang, Q.1
  • 131
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003;423:506-511.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1
  • 132
    • 2442496304 scopus 로고    scopus 로고
    • An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells
    • Vijayakrishnan L, et al. An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells. Immunity 2004;20:563-575.
    • (2004) Immunity , vol.20 , pp. 563-575
    • Vijayakrishnan, L.1
  • 133
    • 1542343979 scopus 로고    scopus 로고
    • Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus
    • Lin SC, et al. Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus. Arthritis Rheum 2004;50:770-775.
    • (2004) Arthritis Rheum , vol.50 , pp. 770-775
    • Lin, S.C.1
  • 134
    • 0346458550 scopus 로고    scopus 로고
    • The systemic lupus erythematosus-associated PDCD1 polymorphism PD1.3A in lupus nephritis
    • Prokunina L, et al. The systemic lupus erythematosus-associated PDCD1 polymorphism PD1.3A in lupus nephritis. Arthritis Rheum 2004;50:327-328.
    • (2004) Arthritis Rheum , vol.50 , pp. 327-328
    • Prokunina, L.1
  • 135
    • 0344099132 scopus 로고    scopus 로고
    • Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes
    • Nielsen C, Hansen D, Husby S, Jacobsen BB, Lillevang ST. Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes. Tissue Antigens 2003;62:492-497.
    • (2003) Tissue Antigens , vol.62 , pp. 492-497
    • Nielsen, C.1    Hansen, D.2    Husby, S.3    Jacobsen, B.B.4    Lillevang, S.T.5
  • 136
    • 13244277850 scopus 로고    scopus 로고
    • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
    • Prokunina L, et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 2002;32:666-669.
    • (2002) Nat Genet , vol.32 , pp. 666-669
    • Prokunina, L.1
  • 137
    • 2942724439 scopus 로고    scopus 로고
    • The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis
    • Greve B, et al. The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. J Immunol 2004;173:157-163.
    • (2004) J Immunol , vol.173 , pp. 157-163
    • Greve, B.1
  • 138
    • 0036738887 scopus 로고    scopus 로고
    • Genetic background determines the requirement for B7 costimulation in induction of autoimmunity
    • Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. Eur J Immunol 2002;32:2687-2697.
    • (2002) Eur J Immunol , vol.32 , pp. 2687-2697
    • Jabs, C.1    Greve, B.2    Chang, T.T.3    Sobel, R.A.4    Sharpe, A.H.5    Kuchroo, V.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.