-
1
-
-
0033757806
-
The protein data bank and the challenge of structural genomics
-
Berman H.M., Bhat T.N., Bourne P.E., Feng Z., Gilliland G., Weissig H., Westbrook J. The protein data bank and the challenge of structural genomics. Nat. Struct. Biol. 7:2000;s957-s959.
-
(2000)
Nat. Struct. Biol.
, vol.7
-
-
Berman, H.M.1
Bhat, T.N.2
Bourne, P.E.3
Feng, Z.4
Gilliland, G.5
Weissig, H.6
Westbrook, J.7
-
2
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno B.M., Collins M. The B7 family of ligands and its receptors. new pathways for costimulation and inhibition of immune responses Annu. Rev. Immunol. 20:2002;29-53.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
3
-
-
0035056017
-
CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
-
Chambers C.A., Kuhns M.S., Egen J.G., Allison J.P. CTLA-4-mediated inhibition in regulation of T cell responses. mechanisms and manipulation in tumor immunotherapy Annu. Rev. Immunol. 19:2001;565-594.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 565-594
-
-
Chambers, C.A.1
Kuhns, M.S.2
Egen, J.G.3
Allison, J.P.4
-
4
-
-
0034177580
-
In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells
-
Chapoval A.I., Tamada K., Chen L. In vitro growth inhibition of a broad spectrum of tumor cell lines by activated human dendritic cells. Blood. 95:2000;2346-2351.
-
(2000)
Blood
, vol.95
, pp. 2346-2351
-
-
Chapoval, A.I.1
Tamada, K.2
Chen, L.3
-
5
-
-
5844252552
-
B7-H3: A costimulatory molecule for t cell activation and ifn-gamma production
-
Chapoval A.I., Ni J., Lau J.S., Wilcox R.A., Flies D.B., Liu D., Dong H., Sica G.L., Zhu G., Tamada K., Chen L. B7-H3. a costimulatory molecule for t cell activation and ifn-gamma production Nat. Immunol. 2:2001;269-274.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 269-274
-
-
Chapoval, A.I.1
Ni, J.2
Lau, J.S.3
Wilcox, R.A.4
Flies, D.B.5
Liu, D.6
Dong, H.7
Sica, G.L.8
Zhu, G.9
Tamada, K.10
Chen, L.11
-
6
-
-
0036634583
-
Immunoglobulin fusion proteins as a tool for evaluation of T-cell costimulatory molecules
-
Chapoval A.I., Zhu G., Chen L. Immunoglobulin fusion proteins as a tool for evaluation of T-cell costimulatory molecules. Mol. Biotechnol. 21:2002;259-264.
-
(2002)
Mol. Biotechnol.
, vol.21
, pp. 259-264
-
-
Chapoval, A.I.1
Zhu, G.2
Chen, L.3
-
7
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H., Zhu G., Tamada K., Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5:1999;1365-1369.
-
(1999)
Nat. Med.
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
8
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H., Strome S.E., Salomao D.R., Tamura H., Hirano F., Flies D.B., Roche P.C., Lu J., Zhu G., Tamada K.et al. Tumor-associated B7-H1 promotes T-cell apoptosis. a potential mechanism of immune evasion Nat. Med. 8:2002;793-800.
-
(2002)
Nat. Med.
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
-
9
-
-
79952608525
-
Accurate bond and angle parameters for X-ray protein structure refinement
-
Engh R.A., Huber R. Accurate bond and angle parameters for X-ray protein structure refinement. Acta Crystallogr. A. 47:1991;392-400.
-
(1991)
Acta Crystallogr. A
, vol.47
, pp. 392-400
-
-
Engh, R.A.1
Huber, R.2
-
10
-
-
0035865077
-
A genomic view of immunology
-
Fahrer A.M., Bazan J.F., Papathanasiou P., Nelms K., Goodnow C.C. A genomic view of immunology. Nature. 409:2001;836-838.
-
(2001)
Nature
, vol.409
, pp. 836-838
-
-
Fahrer, A.M.1
Bazan, J.F.2
Papathanasiou, P.3
Nelms, K.4
Goodnow, C.C.5
-
11
-
-
0028856911
-
Prediction of protein three-dimensional structures in insertion and deletion regions: A procedure for searching databases of representative protein fragments using geometric scoring criteria
-
Fechteler T., Dengler U., Schomburg D. Prediction of protein three-dimensional structures in insertion and deletion regions. a procedure for searching databases of representative protein fragments using geometric scoring criteria J. Mol. Biol. 253:1995;114-131.
-
(1995)
J. Mol. Biol.
, vol.253
, pp. 114-131
-
-
Fechteler, T.1
Dengler, U.2
Schomburg, D.3
-
12
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman G.J., Long A.J., Iwai Y., Bourque K., Chernova T., Nishimura H., Fitz L.J., Malenkovich N., Okazaki T., Byrne M.C.et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192:2000;1027-1034.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
-
13
-
-
0037340349
-
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
-
Grimbacher B., Hutloff A., Schlesier M., Glocker E., Warnatz K., Drager R., Eibel H., Fischer B., Schaffer A.A., Mages H.W.et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat. Immunol. 4:2003;261-268.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 261-268
-
-
Grimbacher, B.1
Hutloff, A.2
Schlesier, M.3
Glocker, E.4
Warnatz, K.5
Drager, R.6
Eibel, H.7
Fischer, B.8
Schaffer, A.A.9
Mages, H.W.10
-
15
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff A., Dittrich A.M., Beier K.C., Eljaschewitsch B., Kraft R., Anagnostopoulos I., Kroczek R.A. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature. 397:1999;263-266.
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
Dittrich, A.M.2
Beier, K.C.3
Eljaschewitsch, B.4
Kraft, R.5
Anagnostopoulos, I.6
Kroczek, R.A.7
-
16
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y., Ishida M., Tanaka Y., Okazaki T., Honjo T., Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. USA. 99:2002;12293-12297.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
17
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
Krummel M.F., Allison J.P. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:1996;2533-2540.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
18
-
-
5844264920
-
PD-L2 is a second ligand for PD-I and inhibits T cell activation
-
Latchman Y., Wood C.R., Chernova T., Chaudhary D., Borde M., Chernova I., Iwai Y., Long A.J., Brown J.A., Nunes R.et al. PD-L2 is a second ligand for PD-I and inhibits T cell activation. Nat. Immunol. 2:2001;261-268.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
-
19
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
Lee K.M., Chuang E., Griffin M., Khattri R., Hong D.K., Zhang W., Straus D., Samelson L.E., Thompson C.B., Bluestone J.A. Molecular basis of T cell inactivation by CTLA-4. Science. 282:1998;2263-2266.
-
(1998)
Science
, vol.282
, pp. 2263-2266
-
-
Lee, K.M.1
Chuang, E.2
Griffin, M.3
Khattri, R.4
Hong, D.K.5
Zhang, W.6
Straus, D.7
Samelson, L.E.8
Thompson, C.B.9
Bluestone, J.A.10
-
20
-
-
0026754015
-
Accurate modeling of protein conformation by automatic segment matching
-
Levitt M. Accurate modeling of protein conformation by automatic segment matching. J. Mol. Biol. 226:1992;507-533.
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 507-533
-
-
Levitt, M.1
-
21
-
-
0034651694
-
Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
-
Ling V., Wu P.W., Finnerty H.F., Bean K.M., Spaulding V., Fouser L.A., Leonard J.P., Hunter S.E., Zollner R., Thomas J.L.et al. Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J. Immunol. 164:2000;1653-1657.
-
(2000)
J. Immunol.
, vol.164
, pp. 1653-1657
-
-
Ling, V.1
Wu, P.W.2
Finnerty, H.F.3
Bean, K.M.4
Spaulding, V.5
Fouser, L.A.6
Leonard, J.P.7
Hunter, S.E.8
Zollner, R.9
Thomas, J.L.10
-
23
-
-
0033999501
-
Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand
-
Mages H.W., Andreas H., Heuck C., Büchner K., Himmelbauer H., Oliveri F., Kroczek R.A. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Eur. J. Immunol. 30:2000;1040-1047.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1040-1047
-
-
Mages, H.W.1
Andreas, H.2
Heuck, C.3
Büchner, K.4
Himmelbauer, H.5
Oliveri, F.6
Kroczek, R.A.7
-
24
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
-
Marengere L.E.M., Waterhouse P., Duncan G.S., Mittrucker H.W., Feng G.S., Mak T.W. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science. 272:1996;1170-1173.
-
(1996)
Science
, vol.272
, pp. 1170-1173
-
-
Marengere, L.E.M.1
Waterhouse, P.2
Duncan, G.S.3
Mittrucker, H.W.4
Feng, G.S.5
Mak, T.W.6
-
25
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura H., Nose M., Hiai H., Minato N., Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity. 11:1999;141-151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
26
-
-
0023155210
-
Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes
-
Ponder J.W., Richards F.M. Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes. J. Mol. Biol. 193:1987;775-791.
-
(1987)
J. Mol. Biol.
, vol.193
, pp. 775-791
-
-
Ponder, J.W.1
Richards, F.M.2
-
27
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
Salomon B., Bluestone J.A. Complexities of CD28/B7. CTLA-4 costimulatory pathways in autoimmunity and transplantation Annu. Rev. Immunol. 19:2001;225-252.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 225-252
-
-
Salomon, B.1
Bluestone, J.A.2
-
28
-
-
0035967157
-
Structural basis for co-stimulation by the human CTLA-4/B7-2 complex
-
Schwartz J.C., Zhang X., Fedorov A.A., Nathenson S.G., Almo S.C. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature. 410:2001;604-608.
-
(2001)
Nature
, vol.410
, pp. 604-608
-
-
Schwartz, J.C.1
Zhang, X.2
Fedorov, A.A.3
Nathenson, S.G.4
Almo, S.C.5
-
29
-
-
0038491416
-
Cooperative B7-1/2 (CD80/CD86) and B7-DC (PD-L2) costimulation of CD4 T cells independent of the PD-1 receptor
-
in press
-
Shin T., Kennedy G., Gorski K., Tsuchiya H., Koseki H., Azuma M., Yagita H., Chen L., Powell J., Pardoll D.M., Housseau F. Cooperative B7-1/2 (CD80/CD86) and B7-DC (PD-L2) costimulation of CD4 T cells independent of the PD-1 receptor. J. Exp. Med. in press:2003.
-
(2003)
J. Exp. Med.
-
-
Shin, T.1
Kennedy, G.2
Gorski, K.3
Tsuchiya, H.4
Koseki, H.5
Azuma, M.6
Yagita, H.7
Chen, L.8
Powell, J.9
Pardoll, D.M.10
Housseau, F.11
-
30
-
-
0035967146
-
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
-
Stamper C.C., Zhang Y., Tobin J.F., Erbe D.V., Ikemizu S., Davis S.J., Stahl M.L., Seehra J., Somers W.S., Mosyak L. Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature. 410:2001;608-611.
-
(2001)
Nature
, vol.410
, pp. 608-611
-
-
Stamper, C.C.1
Zhang, Y.2
Tobin, J.F.3
Erbe, D.V.4
Ikemizu, S.5
Davis, S.J.6
Stahl, M.L.7
Seehra, J.8
Somers, W.S.9
Mosyak, L.10
-
31
-
-
0034117337
-
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway
-
Tamada K., Shimozaki K., Chapoval A.I., Zhu G., Sica G., Flies D., Boone T., Hsu H., Fu Y.X., Nagata S.et al. Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway. Nat. Med. 6:2000;283-289.
-
(2000)
Nat. Med.
, vol.6
, pp. 283-289
-
-
Tamada, K.1
Shimozaki, K.2
Chapoval, A.I.3
Zhu, G.4
Sica, G.5
Flies, D.6
Boone, T.7
Hsu, H.8
Fu, Y.X.9
Nagata, S.10
-
32
-
-
85047686597
-
Blockade of LIGHT-LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease
-
Tamada K., Tamura H., Flies D., Fu Y.X., Celis E., Pease L.R., Blazar B.R., Chen L. Blockade of LIGHT-LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease. J. Clin. Invest. 109:2002;549-557.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 549-557
-
-
Tamada, K.1
Tamura, H.2
Flies, D.3
Fu, Y.X.4
Celis, E.5
Pease, L.R.6
Blazar, B.R.7
Chen, L.8
-
33
-
-
0035869569
-
B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function
-
Tamura H., Dong H., Zhu G., Sica G.L., Flies D.B., Tamada K., Chen L. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood. 97:2001;1809-1816.
-
(2001)
Blood
, vol.97
, pp. 1809-1816
-
-
Tamura, H.1
Dong, H.2
Zhu, G.3
Sica, G.L.4
Flies, D.B.5
Tamada, K.6
Chen, L.7
-
34
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
Tseng S.Y., Otsuji M., Gorski K., Huang X., Slansky J.E., Pai S.I., Shalabi A., Shin T., Pardoll D.M., Tsuchiya H. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193:2001;839-846.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 839-846
-
-
Tseng, S.Y.1
Otsuji, M.2
Gorski, K.3
Huang, X.4
Slansky, J.E.5
Pai, S.I.6
Shalabi, A.7
Shin, T.8
Pardoll, D.M.9
Tsuchiya, H.10
-
35
-
-
0034667688
-
Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS
-
Wang S., Zhu G., Chapoval A.I., Dong H., Tamada K., Ni J., Chen L. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS. Blood. 96:2000;2808-2813.
-
(2000)
Blood
, vol.96
, pp. 2808-2813
-
-
Wang, S.1
Zhu, G.2
Chapoval, A.I.3
Dong, H.4
Tamada, K.5
Ni, J.6
Chen, L.7
-
36
-
-
0037089648
-
Ligand binding sites of inducible costimulator and high avidity mutants with improved function
-
Wang S., Zhu G., Tamada K., Chen L., Bajorath J. Ligand binding sites of inducible costimulator and high avidity mutants with improved function. J. Exp. Med. 195:2002;1033-1041.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1033-1041
-
-
Wang, S.1
Zhu, G.2
Tamada, K.3
Chen, L.4
Bajorath, J.5
-
37
-
-
0038185203
-
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
-
Wang S., Bajorath J., Flies D.B., Dong H., Honjo T., Chen L. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J. Exp. Med. 197:2003;1083-1091.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1083-1091
-
-
Wang, S.1
Bajorath, J.2
Flies, D.B.3
Dong, H.4
Honjo, T.5
Chen, L.6
-
38
-
-
0036195860
-
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors
-
Wilcox R.A., Flies D.B., Zhu G., Johnson A.J., Tamada K., Chapoval A.I., Strome S.E., Pease L.R., Chen L. Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J. Clin. Invest. 109:2002;651-659.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 651-659
-
-
Wilcox, R.A.1
Flies, D.B.2
Zhu, G.3
Johnson, A.J.4
Tamada, K.5
Chapoval, A.I.6
Strome, S.E.7
Pease, L.R.8
Chen, L.9
-
39
-
-
0033576707
-
T-cell co-stimulation through B7RP-1 and ICOS
-
Yoshinaga S.K., Whoriskey J.S., Khare S.D., Sarmiento U., Guo J., Horan T., Shih G., Zhang M., Coccia M.A., Kohno T.et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature. 402:1999;827-832.
-
(1999)
Nature
, vol.402
, pp. 827-832
-
-
Yoshinaga, S.K.1
Whoriskey, J.S.2
Khare, S.D.3
Sarmiento, U.4
Guo, J.5
Horan, T.6
Shih, G.7
Zhang, M.8
Coccia, M.A.9
Kohno, T.10
|