Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

Journal of Experimental Medicine

Volumn 198, Issue 1, 2003, Pages 71-78

  Salama, Alan D ^a,c   Chitnis, Tanuja ^b,c   Imitola, Jaime ^b,c   Akiba, Hisaya ^d   Tushima, Fumihiko ^e   Azuma, Miyuki ^e   Yagita, Hideo ^d   Sayegh, Mohamed H ^a,c   Khoury, Samia J ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Autoimmunity; Costimulation; EAE; T cell; Tolerance

Indexed keywords

AUTOANTIGEN; CD28 ANTIGEN; LIGAND; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY; PROTEIN; PROTEIN ANTIBODY; PROTEIN PROGRAMMED DEATH 1; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; CLINICAL PATHWAY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DETERIORATION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VIVO STUDY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE; WILD TYPE;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; BLOOD PROTEINS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; INTERFERON TYPE II; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELIN-ASSOCIATED GLYCOPROTEIN; OVALBUMIN; PEPTIDES; SPINAL CORD; T-LYMPHOCYTES;

EID: 0037477604     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20022119     Document Type: Article

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