Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis

Journal of Experimental Medicine

Volumn 190, Issue 5, 1999, Pages 733-740

  Chang, Tammy T ^a,c   Jabs, Claudia ^a,c   Sobel, Raymond A ^b,c   Kuchroo, Vijay K ^a,c   Sharpe, Arlene H ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmunity; B7; Costimulation; Experimental autoimmune encephalomyelitis; Knockout mouse

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CYTOKINE; GAMMA INTERFERON; PEPTIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; FEMALE; HELPER CELL; INFLAMMATORY INFILTRATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; T LYMPHOCYTE;

ADOPTIVE TRANSFER; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, CD86; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MYELIN-ASSOCIATED GLYCOPROTEIN; PEPTIDE FRAGMENTS; T-LYMPHOCYTES; VACCINATION;

EID: 0032843342     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.5.733     Document Type: Article

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