PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 29, 2004, Pages 10691-10696

  Latchman, Yvette E ^a   Liang, Spencer C ^a   Wu, Yin ^a   Chernova, Tatyana ^b   Sobel, Raymond A ^c,d   Klemm, Martina ^e   Kuchroo, Vijay K ^a   Freman, Gordon J ^b   Sharpe, Arlene H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^e PROTEOSYS AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; HLA B7 ANTIGEN; LIGAND; PROGRAMMED CELL DEATH 1 LIGAND; UNCLASSIFIED DRUG;

129S4 SVJAE MOUSE; ADOLESCENT; ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CELL SURVIVAL; CELL TRANSFER; CELLULAR IMMUNITY; CLONOGENESIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENCEPHALITOGENIC T LYMPHOCYTE; HOST; HOST TISSUE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TISSUE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD80; BLOOD PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNE TOLERANCE; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; PEPTIDES; PHENOTYPE;

ANIMALIA;

EID: 3242677686     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307252101     Document Type: Article

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