Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells

Journal of Immunology

Volumn 165, Issue 9, 2000, Pages 5035-5040

  McAdam, A J ^a   Chang, T T ^a   Lumelsky, A E ^a   Greenfield, E A ^a   Boussiotis, V A ^a   Duke Cohan, J S ^a   Chernova, T ^a   Malenkovich, N ^a   Jabs, C ^a   Kuchroo, V K ^a   Ling, V ^a   Collins, M ^a   Sharpe, A H ^a   Freeman, G J ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INDUCIBLE COSTIMULATORY MOLECULE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; IMMUNIZATION; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

EID: 0034327808     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.9.5035     Document Type: Article

References (26)

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15. Studies using APCs lacking expression of both B7-B1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2, but not Th1, cytokine production
16. B7-B1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not BT-1 preferentially costimulates the initial production of IL-4
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