Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10

Journal of Experimental Medicine

Volumn 197, Issue 2, 2003, Pages 181-193

  Löhning, Max ^a   Hutloff, Andreas ^b   Kallinich, Tilmann ^b,c   Mages, Hans Werner ^b   Bonhagen, Kerstin ^a   Radbruch, Andreas ^a   Hamelmann, Eckard ^c   Kroczek, Richard A ^b  

^a DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cytokine; Inflammation; T helper cell; T lymphocyte subsets; Th2 cells

Indexed keywords

CYTOKINE; GAMMA INTERFERON; ICOS ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 6; MEMBRANE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DENSITY; CONTROLLED STUDY; CYTOKINE RELEASE; EFFECTOR CELL; IMMUNE SYSTEM; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADOPTIVE TRANSFER; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; OVALBUMIN; PHENOTYPE; TH2 CELLS;

EID: 0037455003     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020632     Document Type: Article

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