Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB

Nature

Volumn 424, Issue 6950, 2003, Pages 797-801

  Brummelkamp, Thijn R ^a   Nijman, Sebastian M B ^a   Dirac, Annette M G ^a   Bernards, René ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; RNA; TUMORS;

PROTEIN MODIFICATION;

GENES;

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID DERIVATIVE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEINASE; UBIQUITIN; CHUK PROTEIN, HUMAN; CYLD PROTEIN, HUMAN; DRUG DERIVATIVE; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR SUPPRESSOR PROTEIN;

CANCER; MEDICINE;

APOPTOSIS; ARTICLE; CANCER CONTROL; CARCINOGENESIS; CELL CYCLE; CONJUGATION; CONTROLLED STUDY; CYLD GENE; CYLINDROMA; ENZYME INHIBITION; GENE ACTIVATION; GENE LOSS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN MODIFICATION; TUMOR SUPPRESSOR GENE; CELL CULTURE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; PROTEIN BINDING; RNA INTERFERENCE;

APOPTOSIS; ASPIRIN; CELL LINE; HUMANS; I-KAPPA B KINASE; NF-KAPPA B; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RNA INTERFERENCE; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

EID: 0042467554     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01811     Document Type: Article

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