메뉴 건너뛰기




Volumn 303, Issue 4, 2003, Pages 1169-1178

Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer

Author keywords

Angiogenesis; Gene therapy; Isoform; Ovarian cancer; RNA interference; VEGF

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; ISOPROTEIN; MESSENGER RNA; RNA DERIVATIVE; VASCULOTROPIN;

EID: 0344211452     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00495-9     Document Type: Article
Times cited : (120)

References (55)
  • 1
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P., Jain R.K. Angiogenesis in cancer and other diseases. Nature. 407:2000;249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 4
    • 0035422178 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
    • Bachelder R.E., Crago A., Chung J., Wendt M.A., Shaw L.M., Robinson G., Mercurio A.M. Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. Cancer Res. 61:2001;5736-5740.
    • (2001) Cancer Res. , vol.61 , pp. 5736-5740
    • Bachelder, R.E.1    Crago, A.2    Chung, J.3    Wendt, M.A.4    Shaw, L.M.5    Robinson, G.6    Mercurio, A.M.7
  • 5
    • 0036899148 scopus 로고    scopus 로고
    • Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma
    • Zhang L., Yang N., Garcia J.R., Mohamed A., Benencia F., Rubin S.C., Allman D., Coukos G. Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma. Am. J. Pathol. 161:2002;2295-2309.
    • (2002) Am. J. Pathol. , vol.161 , pp. 2295-2309
    • Zhang, L.1    Yang, N.2    Garcia, J.R.3    Mohamed, A.4    Benencia, F.5    Rubin, S.C.6    Allman, D.7    Coukos, G.8
  • 6
    • 0030021835 scopus 로고    scopus 로고
    • The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences
    • Shima D.T., Kuroki M., Deutsch U., Ng Y.S., Adamis A.P., D'Amore P.A. The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J. Biol. Chem. 271:1996;3877-3883.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3877-3883
    • Shima, D.T.1    Kuroki, M.2    Deutsch, U.3    Ng, Y.S.4    Adamis, A.P.5    D'Amore, P.A.6
  • 7
    • 0032577873 scopus 로고    scopus 로고
    • Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice
    • Tober K.L., Cannon R.E., Spalding J.W., Oberyszyn T.M., Parrett M.L., Rackoff A.I., Oberyszyn A.S., Tennant R.W., Robertson F.M. Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice. Biochem. Biophys. Res. Commun. 247:1998;644-653.
    • (1998) Biochem. Biophys. Res. Commun. , vol.247 , pp. 644-653
    • Tober, K.L.1    Cannon, R.E.2    Spalding, J.W.3    Oberyszyn, T.M.4    Parrett, M.L.5    Rackoff, A.I.6    Oberyszyn, A.S.7    Tennant, R.W.8    Robertson, F.M.9
  • 8
    • 0035143709 scopus 로고    scopus 로고
    • Differential expression of VEGF isoforms in mouse during development and in the adult
    • Ng Y.S., Rohan R., Sunday M.E., Demello D.E., D'Amore P.A. Differential expression of VEGF isoforms in mouse during development and in the adult. Dev. Dyn. 220:2001;112-121.
    • (2001) Dev. Dyn. , vol.220 , pp. 112-121
    • Ng, Y.S.1    Rohan, R.2    Sunday, M.E.3    Demello, D.E.4    D'Amore, P.A.5
  • 9
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson C.J., Stringer S.E. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J. Cell Sci. 114:2001;853-865.
    • (2001) J. Cell Sci. , vol.114 , pp. 853-865
    • Robinson, C.J.1    Stringer, S.E.2
  • 10
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • Park J.E., Keller G.A., Ferrara N. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol. Biol. Cell. 4:1993;1317-1326.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 11
    • 0035863288 scopus 로고    scopus 로고
    • Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer
    • Yuan A., Yu C.J., Kuo S.H., Chen W.J., Lin F.Y., Luh K.T., Yang P.C., Lee Y.C. Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer. J. Clin. Oncol. 19:2001;432-441.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 432-441
    • Yuan, A.1    Yu, C.J.2    Kuo, S.H.3    Chen, W.J.4    Lin, F.Y.5    Luh, K.T.6    Yang, P.C.7    Lee, Y.C.8
  • 16
    • 0028990151 scopus 로고
    • VEGF121, a vascular endothelial growth factor (VEGF) isoform lacking heparin binding ability, requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells
    • Cohen T., Gitay-Goren H., Sharon R., Shibuya M., Halaban R., Levi B.Z., Neufeld G. VEGF121, a vascular endothelial growth factor (VEGF) isoform lacking heparin binding ability, requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells. J. Biol. Chem. 270:1995;11322-11326.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11322-11326
    • Cohen, T.1    Gitay-Goren, H.2    Sharon, R.3    Shibuya, M.4    Halaban, R.5    Levi, B.Z.6    Neufeld, G.7
  • 18
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • de Vries C., Escobedo J.A., Ueno H., Houck K., Ferrara N., Williams L.T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science. 255:1992;989-991.
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, N.5    Williams, L.T.6
  • 20
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G.H., Rossant J., Gertsenstein M., Breitman M.L. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 376:1995;66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 21
    • 0033830523 scopus 로고    scopus 로고
    • Isoforms of vascular endothelial growth factor act in a coordinate fashion to recruit and expand tumor vasculature
    • Grunstein J., Masbad J.J., Hickey R., Giordano F., Johnson R.S. Isoforms of vascular endothelial growth factor act in a coordinate fashion to recruit and expand tumor vasculature. Mol. Cell Biol. 20:2000;7282-7291.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 7282-7291
    • Grunstein, J.1    Masbad, J.J.2    Hickey, R.3    Giordano, F.4    Johnson, R.S.5
  • 22
    • 0037086082 scopus 로고    scopus 로고
    • Vascular endothelial growth factor isoform expression as a determinant of blood vessel patterning in human melanoma xenografts
    • Yu J.L., Rak J.W., Klement G., Kerbel R.S. Vascular endothelial growth factor isoform expression as a determinant of blood vessel patterning in human melanoma xenografts. Cancer Res. 62:2002;1838-1846.
    • (2002) Cancer Res. , vol.62 , pp. 1838-1846
    • Yu, J.L.1    Rak, J.W.2    Klement, G.3    Kerbel, R.S.4
  • 24
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • Shaheen R.M., Davis D.W., Liu W., Zebrowski B.K., Wilson M.R., Bucana C.D., McConkey D.J., McMahon G., Ellis L.M. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res. 59:1999;5412-5416.
    • (1999) Cancer Res. , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3    Zebrowski, B.K.4    Wilson, M.R.5    Bucana, C.D.6    McConkey, D.J.7    McMahon, G.8    Ellis, L.M.9
  • 26
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta L.G., Chen H., O'Connor S.J., Chisholm V., Meng Y.G., Krummen L., Winkler M., Ferrara N. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res. 57:1997;4593-4599.
    • (1997) Cancer Res. , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5    Krummen, L.6    Winkler, M.7    Ferrara, N.8
  • 28
    • 0029782859 scopus 로고    scopus 로고
    • Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
    • Cheng S.Y., Huang H.J., Nagane M., Ji X.D., Wang D., Shih C.C., Arap W., Huang C.M., Cavenee W.K. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA. 93:1996;8502-8507.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8502-8507
    • Cheng, S.Y.1    Huang, H.J.2    Nagane, M.3    Ji, X.D.4    Wang, D.5    Shih, C.C.6    Arap, W.7    Huang, C.M.8    Cavenee, W.K.9
  • 29
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus M.T., Sharp P.A. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3:2002;737-747.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 30
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir S.M., Harborth J., Weber K., Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 26:2002;199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 31
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature. 418:2002;244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 32
    • 0037213559 scopus 로고    scopus 로고
    • Mammalian RNAi for the masses
    • Shi Y. Mammalian RNAi for the masses. Trends Genet. 19:2003;9-12.
    • (2003) Trends Genet. , vol.19 , pp. 9-12
    • Shi, Y.1
  • 34
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp T.R., Bernards R., Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell. 2:2002;243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 35
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu J.Y., DeRuiter S.L., Turner D.L. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA. 99:2002;6047-6052.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 37
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 38
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison P.J., Caudy A.A., Bernstein E., Hannon G.J., Conklin D.S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:2002;948-958.
    • (2002) Genes Dev. , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 39
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul C.P., Good P.D., Winer I., Engelke D.R. Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20:2002;505-508.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 40
    • 0036245628 scopus 로고    scopus 로고
    • ′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • ′ overhangs efficiently suppress targeted gene expression in mammalian cells Nat. Biotechnol. 20:2002;497-500.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 42
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y., Wagner E.J., Cullen B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell. 9:2002;1327-1333.
    • (2002) Mol. Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 47
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 48
    • 0036245743 scopus 로고    scopus 로고
    • Expanding small RNA interference
    • Tuschl T. Expanding small RNA interference. Nat. Biotechnol. 20:2002;446-448.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 446-448
    • Tuschl, T.1
  • 49
    • 0035008525 scopus 로고    scopus 로고
    • Ovarian surface epithelium: Biology, endocrinology, and pathology
    • Auersperg N., Wong A.S., Choi K.C., Kang S.K., Leung P.C. Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr. Rev. 22:2001;255-288.
    • (2001) Endocr. Rev. , vol.22 , pp. 255-288
    • Auersperg, N.1    Wong, A.S.2    Choi, K.C.3    Kang, S.K.4    Leung, P.C.5
  • 50
    • 0037022382 scopus 로고    scopus 로고
    • Stable suppression of gene expression by RNAi in mammalian cells
    • Paddison P.J., Caudy A.A., Hannon G.J. Stable suppression of gene expression by RNAi in mammalian cells. Proc. Natl. Acad. Sci. USA. 99:2002;1443-1448.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1443-1448
    • Paddison, P.J.1    Caudy, A.A.2    Hannon, G.J.3
  • 51
    • 0029949294 scopus 로고    scopus 로고
    • Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: A comparative study
    • Ilves H., Barske C., Junker U., Bohnlein E., Veres G. Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: a comparative study. Gene. 171:1996;203-208.
    • (1996) Gene , vol.171 , pp. 203-208
    • Ilves, H.1    Barske, C.2    Junker, U.3    Bohnlein, E.4    Veres, G.5
  • 52
    • 0037021437 scopus 로고    scopus 로고
    • Small interfering RNA and gene silencing in transgenic mice and rats
    • Hasuwa H., Kaseda K., Einarsdottir T., Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532:2002;227-230.
    • (2002) FEBS Lett. , vol.532 , pp. 227-230
    • Hasuwa, H.1    Kaseda, K.2    Einarsdottir, T.3    Okabe, M.4
  • 53
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • Qin X.F., An D.S., Chen I.S., Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA. 100:2003;183-188.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 54
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G., Singer O., Ikawa M., Verma I.M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA. 110:2003;1844-1848.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.