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Volumn 421, Issue 6920, 2003, Pages 231-237

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; DNA SEQUENCES; GENETIC ENGINEERING; MICROORGANISMS; RNA; YEAST;

EID: 0037448540     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01278     Document Type: Article
Times cited : (2949)

References (39)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1
  • 2
    • 0034676457 scopus 로고    scopus 로고
    • Functional genomic analysis of C. elegans chromosome 1 by systematic RNA interference
    • Fraser, A. G. et al. Functional genomic analysis of C. elegans chromosome 1 by systematic RNA interference. Nature 408, 325-330 (2000).
    • (2000) Nature , vol.408 , pp. 325-330
    • Fraser, A.G.1
  • 3
    • 0035128859 scopus 로고    scopus 로고
    • Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi
    • Maeda, I., Kohara, Y., Yamamoto, M. & Sugimoto, A. Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr. Biol. 11, 171-176 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 171-176
    • Maeda, I.1    Kohara, Y.2    Yamamoto, M.3    Sugimoto, A.4
  • 4
    • 0034676448 scopus 로고    scopus 로고
    • Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
    • Gonczy, P. et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408, 331-336 (2000).
    • (2000) Nature , vol.408 , pp. 331-336
    • Gonczy, P.1
  • 5
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons, L. & Fire, A. Specific interference by ingested dsRNA. Nature 395, 854 (1998).
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 6
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons, L., Court, D. L. & Fire, A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263, 103-112 (2001).
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 7
    • 0035229245 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in C elegans
    • Kamath, R. K., Martinez-Campos, M., Zipperlen, P., Fraser, A. G. & Ahringer, J. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in C elegans. Genome Biol. 2, 1-10 (2001).
    • (2001) Genome Biol. , vol.2 , pp. 1-10
    • Kamath, R.K.1    Martinez-Campos, M.2    Zipperlen, P.3    Fraser, A.G.4    Ahringer, J.5
  • 8
    • 0027533267 scopus 로고
    • Cytosolic Sec 13p complex is required for vesicle formation from the endoplasmic reticulum in vitro
    • Pryer, N. K., Salama, N. R., Schekman, R. & Kaiser, C. A. Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J. Cell Biol. 120, 865-875 (1993).
    • (1993) J. Cell Biol. , vol.120 , pp. 865-875
    • Pryer, N.K.1    Salama, N.R.2    Schekman, R.3    Kaiser, C.A.4
  • 9
    • 0033968037 scopus 로고    scopus 로고
    • Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
    • Tavernarakis, N., Wang, S. L., Dorovkov, M., Ryazanov, A. & Driscoll, M. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes. Nature Genet. 24, 180-183 (2000).
    • (2000) Nature Genet. , vol.24 , pp. 180-183
    • Tavernarakis, N.1    Wang, S.L.2    Dorovkov, M.3    Ryazanov, A.4    Driscoll, M.5
  • 10
    • 0034649570 scopus 로고    scopus 로고
    • RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans
    • Piano, F., Schetter, A. J., Mangone, M., Stein, L. & Kemphues, K. I. RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans. Curr. Biol. 10, 1619-1622 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 1619-1622
    • Piano, F.1    Schetter, A.J.2    Mangone, M.3    Stein, L.4    Kemphues, K.I.5
  • 11
    • 0033983822 scopus 로고    scopus 로고
    • MIPS: A database for genomes and protein sequences
    • Mewes, H. W. et al. MIPS: a database for genomes and protein sequences. Nucleic Acids Res. 28, 37-40 (2000).
    • (2000) Nucleic Acids Res. , vol.28 , pp. 37-40
    • Mewes, H.W.1
  • 12
    • 0035166973 scopus 로고    scopus 로고
    • The InterPro database, an integrated documentation resource for protein families, domains and functional sites
    • Apweiler, R. et al. The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic Acids Res. 29, 37-40 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. 37-40
    • Apweiler, R.1
  • 13
    • 0034708480 scopus 로고    scopus 로고
    • The genome sequence of Drosophila melanogaster
    • Adams, M. D. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185-2195 (2000).
    • (2000) Science , vol.287 , pp. 2185-2195
    • Adams, M.D.1
  • 14
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
    • (2001) Nature , vol.409 , pp. 860-921
  • 15
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter, J. C. et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1
  • 16
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 genes
    • Goffeau, A. et al. Life with 6000 genes. Science 274, 563-567 (1996) 546.
    • (1996) Science , vol.274 , pp. 563-567
    • Goffeau, A.1
  • 17
    • 0034649566 scopus 로고    scopus 로고
    • Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
    • Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408, 796-815 (2000).
    • (2000) Nature , vol.408 , pp. 796-815
  • 18
    • 0032509302 scopus 로고    scopus 로고
    • The C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: A platform for investigating biology
    • The C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282, 2012-2018 (1998).
    • (1998) Science , vol.282 , pp. 2012-2018
  • 19
    • 0032888795 scopus 로고    scopus 로고
    • Developmental genetics of Caenorhabditis elegans sex determination
    • Kuwabara, P. E. Developmental genetics of Caenorhabditis elegans sex determination. Curr. Top. Dev. Biol. 41, 99-132 (1999).
    • (1999) Curr. Top. Dev. Biol. , vol.41 , pp. 99-132
    • Kuwabara, P.E.1
  • 20
    • 0033639116 scopus 로고    scopus 로고
    • A global profile of germline gene expression in C. elegans
    • Reinke, V. et al. A global profile of germline gene expression in C. elegans. Mol. Cell 6, 605-616 (2000).
    • (2000) Mol. Cell , vol.6 , pp. 605-616
    • Reinke, V.1
  • 21
    • 0036333386 scopus 로고    scopus 로고
    • X-chromosome silencing in the germline of C. elegans
    • Kelly, W. G. et al. X-chromosome silencing in the germline of C. elegans. Development 129, 479-492 (2002).
    • (2002) Development , vol.129 , pp. 479-492
    • Kelly, W.G.1
  • 22
    • 0029098961 scopus 로고
    • Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans
    • Barnes, T. M., Kohara, Y., Coulson, A. & Hekimi, S. Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. Genetics 141, 159-179 (1995).
    • (1995) Genetics , vol.141 , pp. 159-179
    • Barnes, T.M.1    Kohara, Y.2    Coulson, A.3    Hekimi, S.4
  • 23
    • 0035860551 scopus 로고    scopus 로고
    • A gene expression map for Caenorhabditis elegans
    • Kim, S. K. et al. A gene expression map for Caenorhabditis elegans. Science 293, 2087-2092 (2001).
    • (2001) Science , vol.293 , pp. 2087-2092
    • Kim, S.K.1
  • 24
    • 0036613754 scopus 로고    scopus 로고
    • Clustering of housekeeping genes provides a unified model of gene order in the human genome
    • Lercher, M. J., Urrutia, A. O. & Hurst, L. D. Clustering of housekeeping genes provides a unified model of gene order in the human genome. Nature Genet. 31, 180-183 (2002).
    • (2002) Nature Genet. , vol.31 , pp. 180-183
    • Lercher, M.J.1    Urrutia, A.O.2    Hurst, L.D.3
  • 25
    • 0003328368 scopus 로고    scopus 로고
    • Evidence for large domains of similarly expressed genes in the Drosophila genome
    • paper no. 5
    • Spellman, P. T. & Rubin, G. M. Evidence for large domains of similarly expressed genes in the Drosophila genome. J. Biol. 1(1), paper no. 5 (http://jbiol.com/content/1/1/5) (2002).
    • (2002) J. Biol. , vol.1 , Issue.1
    • Spellman, P.T.1    Rubin, G.M.2
  • 26
    • 0033780450 scopus 로고    scopus 로고
    • A computational analysis of wholegenome expression data reveals chromosomal domains of gene expression
    • Cohen, B. A., Mitra, R. D., Hughes, J. D. & Church, G. M. A computational analysis of wholegenome expression data reveals chromosomal domains of gene expression. Nature Genet. 26, 183-186 (2000).
    • (2000) Nature Genet. , vol.26 , pp. 183-186
    • Cohen, B.A.1    Mitra, R.D.2    Hughes, J.D.3    Church, G.M.4
  • 27
    • 0037194732 scopus 로고    scopus 로고
    • Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans
    • Roy, P. J., Stuart, J., Lund, J. & Kim, S. K. Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans. Nature 418, 975-9 (2002).
    • (2002) Nature , vol.418 , pp. 975-979
    • Roy, P.J.1    Stuart, J.2    Lund, J.3    Kim, S.K.4
  • 28
    • 0034161444 scopus 로고    scopus 로고
    • Regulation of adjacent yeast genes
    • Kruglyak, S. & Tang, H. Regulation of adjacent yeast genes. Trends Genet. 16, 109-111 (2000).
    • (2000) Trends Genet. , vol.16 , pp. 109-111
    • Kruglyak, S.1    Tang, H.2
  • 29
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J. & Conklin, D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 30
    • 0012756249 scopus 로고    scopus 로고
    • RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
    • Donze, O. & Picard, D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30, e46 (http://nar.oupjournals.org/cgi/content/full/30/10/e46) (2002).
    • (2002) Nucleic Acids Res. , vol.30
    • Donze, O.1    Picard, D.2
  • 31
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir, S. M., Harborth, J., Weber, K. & Tuschl, T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26, 199-213 (2002).
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 32
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul, C. P., Good, P. D., Winer, I. & Engelke, D. R. Effective expression of small interfering RNA in human cells. Nature Biotechnol. 20, 505-8 (2002).
    • (2002) Nature Biotechnol. , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 33
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi, M. & Taira, K. U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nature Biotechnol. 20, 497-500 (2002).
    • (2002) Nature Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 34
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
    • Sui, G. et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99, 5515-5520 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5515-5520
    • Sui, G.1
  • 36
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PS1-BLAST: A new generation of protein database search programs
    • Altschul, S. F. et al. Gapped BLAST and PS1-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1
  • 37
    • 0030920610 scopus 로고    scopus 로고
    • Sequence mapping by electronic PCR
    • Schuler, G. D. Sequence mapping by electronic PCR. Genome Res. 7, 541-550 (1997).
    • (1997) Genome Res. , vol.7 , pp. 541-550
    • Schuler, G.D.1
  • 38
    • 0034708444 scopus 로고    scopus 로고
    • Comparative genomics of the eukaryotes
    • Rubin, G. M. et al. Comparative genomics of the eukaryotes. Science 287, 2204-2215 (2000).
    • (2000) Science , vol.287 , pp. 2204-2215
    • Rubin, G.M.1
  • 39
    • 0037148758 scopus 로고    scopus 로고
    • The genome sequence of Schizosaccharomyces pombe
    • Wood, V. et al. The genome sequence of Schizosaccharomyces pombe. Nature 415, 871-880 (2002).
    • (2002) Nature , vol.415 , pp. 871-880
    • Wood, V.1


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