Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells

Gene Therapy

Volumn 10, Issue 24, 2003, Pages 2046-2050

  Park, W S ^a   Hayafune, M ^a   Miyano Kurosaki, N ^a   Takaku, H ^a  

^a CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Antiviral RNAi technology; HIV 1 env genes; PBMCs; RNA interference; Small interfering RNAs

Indexed keywords

ANTIVIRUS AGENT; CD4 ANTIGEN; COMPLEMENTARY RNA; DOUBLE STRANDED RNA; GLYCOPROTEIN GP 120; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG BINDING SITE; DRUG COST; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MONONUCLEAR CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RNA SYNTHESIS; VIRAL GENE DELIVERY SYSTEM; VIRUS GENE; VIRUS INHIBITION; VIRUS INTERFERENCE; VIRUS MORPHOLOGY; VIRUS REPLICATION;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; COS CELLS; GENE SILENCING; GENE THERAPY; GENES, ENV; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MOLECULAR SEQUENCE DATA; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA, VIRAL; VIRUS REPLICATION;

EUKARYOTA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; RNA VIRUSES;

EID: 0242440877     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302099     Document Type: Article

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