RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity

Biochemical and Biophysical Research Communications

Volumn 311, Issue 3, 2003, Pages 786-792

  Duxbury, Mark S ^a   Ito, Hiromichi ^a   Benoit, Eric ^a   Zinner, Michael J ^a   Ashley, Stanley W ^a   Whang, Edward E ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Adenocarcinoma; Cancer; FAK; Focal adhesion kinase; Gemcitabine; Interference; Pancreatic; RNA; siRNA

Indexed keywords

FOCAL ADHESION KINASE; FOCAL ADHESION KINASE SMALL INTERFERING RNA; GEMCITABINE; PROTEIN KINASE B; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER MODEL; CANCER RESISTANCE; CELL PROLIFERATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUDE MOUSE; ORTHOTOPIC TRANSPLANTATION; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; TUMOR XENOGRAFT; WESTERN BLOTTING;

MUS MUSCULUS;

EID: 0242493171     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.10.060     Document Type: Article

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