-
1
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner G.G., Wong C.W. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120:1984;885-890.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
2
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters C.L., Simms G., Weinman N.A., Multhaup G., McDonald B.L., Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA. 82:1985;4245-4249.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
3
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner G.G., Wong C.W. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun. 122:1984;1131-1135.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
4
-
-
0025840201
-
BetaA4 amyloid protein deposition in brain after head trauma
-
Roberts G.W., Gentleman S.M., Lynch A., Graham D.I. BetaA4 amyloid protein deposition in brain after head trauma. Lancet. 338:1991;1422-1423.
-
(1991)
Lancet
, vol.338
, pp. 1422-1423
-
-
Roberts, G.W.1
Gentleman, S.M.2
Lynch, A.3
Graham, D.I.4
-
5
-
-
0023737806
-
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: Prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques
-
Davies L., Wolska B., Hilbich C., Multhaup G., Martins R., Simms G., Beyreuther K., Masters C.L. A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques. Neurology. 38:1988;1688-1693.
-
(1988)
Neurology
, vol.38
, pp. 1688-1693
-
-
Davies, L.1
Wolska, B.2
Hilbich, C.3
Multhaup, G.4
Martins, R.5
Simms, G.6
Beyreuther, K.7
Masters, C.L.8
-
6
-
-
0027250352
-
Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments
-
Siman R., Mistretta S., Durkin J.T., Savage M.J., Loh T., Trusko S., Scott R.W. Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments. J. Biol. Chem. 268:1993;16602-16609.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 16602-16609
-
-
Siman, R.1
Mistretta, S.2
Durkin, J.T.3
Savage, M.J.4
Loh, T.5
Trusko, S.6
Scott, R.W.7
-
7
-
-
0023132387
-
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
-
Goldgaber D., Lerman M.I., McBride O.W., Saffiotti U., Gajdusek D.C. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science. 235:1987;877-880.
-
(1987)
Science
, vol.235
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.I.2
McBride, O.W.3
Saffiotti, U.4
Gajdusek, D.C.5
-
8
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325:1987;733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
9
-
-
0023109592
-
Amyloid beta protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi R.E., Gusella J.F., Watkins P.C., Bruns G.A., St. George-Hyslop P., Van Keuren M.L., Patterson D., Pagan S., Kurnit D.M., Neve R.L. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science. 235:1987;880-884.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St. George-Hyslop, P.5
Van Keuren, M.L.6
Patterson, D.7
Pagan, S.8
Kurnit, D.M.9
Neve, R.L.10
-
10
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M.C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L., et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349:1991;704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
-
11
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as beta-secretase
-
Hussain I., Powell D., Howlett D.R., Tew D.G., Meek T.D., Chapman C., Gloger I.S., Murphy K.E., Southan C.D., Ryan D.M., Smith T.S., Simmons D.L., Walsh F.S., Dingwall C., Christie G. Identification of a novel aspartic protease (Asp 2) as beta-secretase. Mol. Cell. Neurosci. 14:1999;419-427.
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
12
-
-
0033518251
-
Purification and cloning of amyloid precursor protein beta-secretase from human brain
-
Sinha S., Anderson J.P., Barbour R., Basi G.S., Caccavello R., Davis D., Doan M., Dovey H.F., Frigon N., Hong J., Jacobson-Croak K., Jewett N., Keim P., Knops J., Lieberburg I., Power M., Tan H., Tatsuno G., Tung J., Schenk D., Seubert P., Suomensaari S.M., Wang S., Walker D., John V., et al. Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature. 402:1999;537-540.
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
John, V.25
more..
-
13
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R., Bennett B.D., Babu-Khan S., Kahn S., Mendiaz E.A., Denis P., Teplow D.B., Ross S., Amarante P., Loeloff R., Luo Y., Fisher S., Fuller J., Edenson S., Lile J., Jarosinski M.A., Biere A.L., Curran E., Burgess T., Louis J.C., Collins F., Treanor J., Rogers G., Citron M. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 286:1999;735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
14
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
Yan R., Bienkowski M.J., Shuck M.E., Miao H., Tory M.C., Pauley A.M., Brashier J.R., Stratman N.C., Mathews W.R., Buhl A.E., Carter D.B., Tomasselli A.G., Parodi L.A., Heinrikson R.L., Gurney M.E. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity. Nature. 402:1999;533-537.
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
15
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe M.S., Xia W., Ostaszewski B.L., Diehl T.S., Kimberly W.T., Selkoe D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature. 398:1999;513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
16
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
-
Yu G., Nishimura M., Arawaka S., Levitan D., Zhang L., Tandon A., Song Y.Q., Rogaeva E., Chen F., Kawarai T., Supala A., Levesque L., Yu H., Yang D.S., Holmes E., Milman P., Liang Y., Zhang D.M., Xu D.H., Sato C., Rogaev E., Smith M., Janus C., Zhang Y., Aebersold R., Farrer L.S., Sorbi S., Bruni A., Fraser P., St. George-Hyslop P. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407:2000;48-54.
-
(2000)
Nature
, vol.407
, pp. 48-54
-
-
Yu, G.1
Nishimura, M.2
Arawaka, S.3
Levitan, D.4
Zhang, L.5
Tandon, A.6
Song, Y.Q.7
Rogaeva, E.8
Chen, F.9
Kawarai, T.10
Supala, A.11
Levesque, L.12
Yu, H.13
Yang, D.S.14
Holmes, E.15
Milman, P.16
Liang, Y.17
Zhang, D.M.18
Xu, D.H.19
Sato, C.20
Rogaev, E.21
Smith, M.22
Janus, C.23
Zhang, Y.24
Aebersold, R.25
Farrer, L.S.26
Sorbi, S.27
Bruni, A.28
Fraser, P.29
St. George-Hyslop, P.30
more..
-
17
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H., Barger S., Barnum S., Bradt B., Bauer J., Cole G.M., Cooper N.R., Eikelenboom P., Emmerling M., Fiebich B.L., Finch C.E., Frautschy S., Griffin W.S., Hampel H., Hull M., Landreth G., Lue L., Mrak R., Mackenzie I.R., McGeer P.L., O'Banion M.K., Pachter J., Pasinetti G., Plata-Salaman C., Rogers J., Rydel R., Shen Y., Streit W., Strohmeyer R., Tooyoma I., Van Muiswinkel F.L., Veerhuis R., Walker D., Webster S., Wegrzyniak B., Wenk G., Wyss-Coray T. Inflammation and Alzheimer's disease. Neurobiol Aging. 21:2000;383-421.
-
(2000)
Neurobiol Aging.
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
Cooper, N.R.7
Eikelenboom, P.8
Emmerling, M.9
Fiebich, B.L.10
Finch, C.E.11
Frautschy, S.12
Griffin, W.S.13
Hampel, H.14
Hull, M.15
Landreth, G.16
Lue, L.17
Mrak, R.18
Mackenzie, I.R.19
McGeer, P.L.20
O'Banion, M.K.21
Pachter, J.22
Pasinetti, G.23
Plata-Salaman, C.24
Rogers, J.25
Rydel, R.26
Shen, Y.27
Streit, W.28
Strohmeyer, R.29
Tooyoma, I.30
Van Muiswinkel, F.L.31
Veerhuis, R.32
Walker, D.33
Webster, S.34
Wegrzyniak, B.35
Wenk, G.36
Wyss-Coray, T.37
more..
-
18
-
-
0002451682
-
Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits
-
K. Iqbal, S.S. Sisodia, & B. Winblad. Wiley
-
Atwood C.S., Huang X., Moir R.D., Smith M.A., Tanzi R.E., Roher A.E., Bush A.I., Perry G. Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits. Iqbal K., Sisodia S.S., Winblad B. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics. 2001;341-361 Wiley.
-
(2001)
Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics
, pp. 341-361
-
-
Atwood, C.S.1
Huang, X.2
Moir, R.D.3
Smith, M.A.4
Tanzi, R.E.5
Roher, A.E.6
Bush, A.I.7
Perry, G.8
-
19
-
-
0033751421
-
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease
-
Smith M.A., Nunomura A., Zhu X., Takeda A., Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid. Redox Signal. 2:2000;413-420.
-
(2000)
Antioxid. Redox Signal.
, vol.2
, pp. 413-420
-
-
Smith, M.A.1
Nunomura, A.2
Zhu, X.3
Takeda, A.4
Perry, G.5
-
20
-
-
0033758324
-
Neuronal oxidative stress precedes amyloid-β deposition in Down syndrome
-
Nunomura A., Perry G., Pappolla M.A., Friedland R.P., Hirai K., Chiba S., Smith M.A. Neuronal oxidative stress precedes amyloid-β deposition in Down syndrome. J. Neuropathol. Exp. Neurol. 59:(11):2000;1011-1017.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, Issue.11
, pp. 1011-1017
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Friedland, R.P.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
21
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E.K., Jones P.K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C.S., Petersen R.B., Smith M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60:2001;759-767.
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
22
-
-
0033957486
-
Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells
-
Olivieri G., Brack C., Muller-Spahn F., Stahelin H.B., Herrmann M., Renard P., Brockhaus M., Hock C. Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells. J. Neurochem. 74:2000;231-236.
-
(2000)
J. Neurochem.
, vol.74
, pp. 231-236
-
-
Olivieri, G.1
Brack, C.2
Muller-Spahn, F.3
Stahelin, H.B.4
Herrmann, M.5
Renard, P.6
Brockhaus, M.7
Hock, C.8
-
23
-
-
0030885482
-
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
-
Smith M.A., Harris P.L.R., Sayre L.M., Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc. Natl. Acad. Sci. USA. 94:1997;9866-9868.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.R.2
Sayre, L.M.3
Perry, G.4
-
24
-
-
0028609520
-
Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease
-
Smith M.A., Richey P.L., Taneda S., Kutty R.K., Sayre L.M., Monnier V.M., Perry G. Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease. Ann. N. Y. Acad. Sci. 738:1994;447-454.
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.738
, pp. 447-454
-
-
Smith, M.A.1
Richey, P.L.2
Taneda, S.3
Kutty, R.K.4
Sayre, L.M.5
Monnier, V.M.6
Perry, G.7
-
25
-
-
0032613038
-
The role of free radicals and metal ions in the pathogenesis of Alzheimer's disease. Interrelations between free radicals and metal ions in life processes
-
A. Sigel, & H. Sigel. New York, Basel, Hong Kong: Marcel Dekker
-
Atwood C.S., Huang X., Moir R.D., Tanzi R.E., Bush A.I. The role of free radicals and metal ions in the pathogenesis of Alzheimer's disease. Interrelations between free radicals and metal ions in life processes. Sigel A., Sigel H. Metal Ions in Biological Systems. Vol. 36:1999;309-364 Marcel Dekker, New York, Basel, Hong Kong.
-
(1999)
Metal Ions in Biological Systems
, vol.36
, pp. 309-364
-
-
Atwood, C.S.1
Huang, X.2
Moir, R.D.3
Tanzi, R.E.4
Bush, A.I.5
-
26
-
-
0026041595
-
Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease
-
Review
-
Basun H., Forssell L.G., Wetterberg L., Winblad B. Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease. J. Neural Transm. Park. Dis. Dement. Sect. 3:(4):1991;231-258. Review.
-
(1991)
J. Neural Transm. Park. Dis. Dement. Sect.
, vol.3
, Issue.4
, pp. 231-258
-
-
Basun, H.1
Forssell, L.G.2
Wetterberg, L.3
Winblad, B.4
-
27
-
-
0030569306
-
Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders
-
Loeffler D.A., LeWitt P.A., Juneau P.L., Sima A.A., Nguyen H.U., DeMaggio A.J., Brickman C.M., Brewer G.J., Dick R.D., Troyer M.D., Kanaley L. Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders. Brain Res. 738:1996;265-274.
-
(1996)
Brain Res.
, vol.738
, pp. 265-274
-
-
Loeffler, D.A.1
LeWitt, P.A.2
Juneau, P.L.3
Sima, A.A.4
Nguyen, H.U.5
DeMaggio, A.J.6
Brickman, C.M.7
Brewer, G.J.8
Dick, R.D.9
Troyer, M.D.10
Kanaley, L.11
-
28
-
-
0033006576
-
Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
-
Castellani R.J., Smith M.A., Nunomura A., Harris P.L., Perry G. Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin? Free Radic. Biol. Med. 26:1999;1508-1512.
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 1508-1512
-
-
Castellani, R.J.1
Smith, M.A.2
Nunomura, A.3
Harris, P.L.4
Perry, G.5
-
30
-
-
0031038634
-
Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury
-
Xiong Y., Gu Q., Peterson P.L., Muizelaar J.P., Lee C.P. Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J. Neurotrauma. 14:1997;23-34.
-
(1997)
J. Neurotrauma
, vol.14
, pp. 23-34
-
-
Xiong, Y.1
Gu, Q.2
Peterson, P.L.3
Muizelaar, J.P.4
Lee, C.P.5
-
31
-
-
0025845529
-
Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells
-
Abe K., St. George-Hyslop P.H., Tanzi R.E., Kogure K. Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells. Neurosci. Lett. 125:1991;169-171.
-
(1991)
Neurosci. Lett.
, vol.125
, pp. 169-171
-
-
Abe, K.1
St. George-Hyslop, P.H.2
Tanzi, R.E.3
Kogure, K.4
-
32
-
-
0028802605
-
Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils
-
Hall E.D., Oostveen J.A., Dunn E., Carter D.B. Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils. Exp. Neurol. 135:1995;17-27.
-
(1995)
Exp. Neurol.
, vol.135
, pp. 17-27
-
-
Hall, E.D.1
Oostveen, J.A.2
Dunn, E.3
Carter, D.B.4
-
33
-
-
0028865755
-
Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain
-
Jendroska K., Poewe W., Daniel S.E., Pluess J., Iwerssen-Schmidt H., Paulsen J., Barthel S., Schelosky L., Cervos-Navarro J., DeArmond S.J. Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain. Acta Neuropathol. (Berl). 90:1995;461-466.
-
(1995)
Acta Neuropathol. (Berl).
, vol.90
, pp. 461-466
-
-
Jendroska, K.1
Poewe, W.2
Daniel, S.E.3
Pluess, J.4
Iwerssen-Schmidt, H.5
Paulsen, J.6
Barthel, S.7
Schelosky, L.8
Cervos-Navarro, J.9
DeArmond, S.J.10
-
34
-
-
0031770501
-
Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus
-
Murakami N., Yamaki T., Iwamoto Y., Sakakibara T., Kobori N., Fushiki S., Ueda S. Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus. J. Neurotrauma. 15:1998;993-1003.
-
(1998)
J. Neurotrauma
, vol.15
, pp. 993-1003
-
-
Murakami, N.1
Yamaki, T.2
Iwamoto, Y.3
Sakakibara, T.4
Kobori, N.5
Fushiki, S.6
Ueda, S.7
-
35
-
-
0030727701
-
Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells
-
Shi J., Xiang Y., Simpkins J.W. Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells. Brain Res. 772:1997;247-251.
-
(1997)
Brain Res.
, vol.772
, pp. 247-251
-
-
Shi, J.1
Xiang, Y.2
Simpkins, J.W.3
-
36
-
-
0032501198
-
Estrogen attenuates over-expression of beta-amyloid precursor protein messenger RNA in an animal model of focal ischemia
-
Shi J., Panickar K.S., Yang S.H., Rabbani O., Day A.L., Simpkins J.W. Estrogen attenuates over-expression of beta-amyloid precursor protein messenger RNA in an animal model of focal ischemia. Brain Res. 810:1998;87-92.
-
(1998)
Brain Res.
, vol.810
, pp. 87-92
-
-
Shi, J.1
Panickar, K.S.2
Yang, S.H.3
Rabbani, O.4
Day, A.L.5
Simpkins, J.W.6
-
37
-
-
0034603414
-
Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease
-
Shi J., Perry G., Smith M.A., Friedland R.P. Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease. Neurobiol. Aging. 21:2000;357-361.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 357-361
-
-
Shi, J.1
Perry, G.2
Smith, M.A.3
Friedland, R.P.4
-
38
-
-
0029907514
-
Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia
-
Yokota M., Saido T.C., Tani E., Yamaura I., Minami N. Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia. J. Cereb. Blood Flow Metab. 16:1996;1219-1223.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 1219-1223
-
-
Yokota, M.1
Saido, T.C.2
Tani, E.3
Yamaura, I.4
Minami, N.5
-
39
-
-
0028200649
-
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
-
Gabuzda D., Busciglio J., Chen L.B., Matsudaira P., Yankner B.A. Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J. Biol. Chem. 269:1994;13623-13628.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13623-13628
-
-
Gabuzda, D.1
Busciglio, J.2
Chen, L.B.3
Matsudaira, P.4
Yankner, B.A.5
-
40
-
-
0032454039
-
Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease
-
Mattson M.P., Pedersen W.A. Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease. Int. J. Dev. Neurosci. 16:1998;737-753.
-
(1998)
Int. J. Dev. Neurosci.
, vol.16
, pp. 737-753
-
-
Mattson, M.P.1
Pedersen, W.A.2
-
41
-
-
0029985732
-
Oxidative stress increases production of β-amyloid precursor protein and β-amyloid (Aβ) in mammalian lenses, and Aβ has toxic effects on lens epithelial cells
-
Frederiske P.H., Garland D., Zigler J.S. Jr., Piatigorsky J. Oxidative stress increases production of β-amyloid precursor protein and β-amyloid (Aβ) in mammalian lenses, and Aβ has toxic effects on lens epithelial cells. J. Biol. Chem. 271:1996;10169-10174.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10169-10174
-
-
Frederiske, P.H.1
Garland, D.2
Zigler J.S., Jr.3
Piatigorsky, J.4
-
42
-
-
0034643895
-
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells
-
Misonou H., Morishima-Kawashima M., Ihara Y. Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry. 39:2000;6951-6959.
-
(2000)
Biochemistry
, vol.39
, pp. 6951-6959
-
-
Misonou, H.1
Morishima-Kawashima, M.2
Ihara, Y.3
-
43
-
-
0034754471
-
Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion
-
Olivieri G., Hess C., Savaskan E., Ly C., Meier F., Baysang G., Brockhaus M., Muller-Spahn F. Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion. J. Pineal Res. 31:2001;320-325.
-
(2001)
J. Pineal Res.
, vol.31
, pp. 320-325
-
-
Olivieri, G.1
Hess, C.2
Savaskan, E.3
Ly, C.4
Meier, F.5
Baysang, G.6
Brockhaus, M.7
Muller-Spahn, F.8
-
44
-
-
0031587950
-
Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells
-
Zhang L., Zhao B., Yew D.T., Kusiak J.W., Roth G.S. Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells. Biochem. Biophys. Res. Commun. 235:1997;845-848.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 845-848
-
-
Zhang, L.1
Zhao, B.2
Yew, D.T.3
Kusiak, J.W.4
Roth, G.S.5
-
45
-
-
0034673209
-
Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells
-
Paola D., Domenicotti C., Nitti M., Vitali A., Borghi R., Cottalasso D., Zaccheo D., Odetti P., Strocchi P., Marinari U.M., Tabaton M., Pronzato M.A. Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells. Biochem. Biophys. Res. Commun. 268:2000;642-646.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.268
, pp. 642-646
-
-
Paola, D.1
Domenicotti, C.2
Nitti, M.3
Vitali, A.4
Borghi, R.5
Cottalasso, D.6
Zaccheo, D.7
Odetti, P.8
Strocchi, P.9
Marinari, U.M.10
Tabaton, M.11
Pronzato, M.A.12
-
46
-
-
0029076397
-
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide
-
Yan S.D., Yan S.F., Chen X., Fu J., Chen M., Kuppusamy P., Smith M.A., Perry G., Godman G.C., Nawroth P., et al. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat. Med. 1:1995;693-699.
-
(1995)
Nat. Med.
, vol.1
, pp. 693-699
-
-
Yan, S.D.1
Yan, S.F.2
Chen, X.3
Fu, J.4
Chen, M.5
Kuppusamy, P.6
Smith, M.A.7
Perry, G.8
Godman, G.C.9
Nawroth, P.10
-
47
-
-
0005342374
-
Antioxidants mimic the ability of chorionic gonadotropin to suppress apoptosis in the rabbit corpus luteum in vitro: A novel role for superoxide dismutase in regulating bax expression
-
Dharmarajan A.M., Hisheh S., Singh B., Parkinson S., Tilly K.I., Tilly J.L. Antioxidants mimic the ability of chorionic gonadotropin to suppress apoptosis in the rabbit corpus luteum in vitro: a novel role for superoxide dismutase in regulating bax expression. Endocrinol. J. 2:1999;295-303.
-
(1999)
Endocrinol. J.
, vol.2
, pp. 295-303
-
-
Dharmarajan, A.M.1
Hisheh, S.2
Singh, B.3
Parkinson, S.4
Tilly, K.I.5
Tilly, J.L.6
-
48
-
-
0026674020
-
Superoxide dismutase activity, lipid peroxide production and corpus luteum steroidogenesis during natural luteolysis and regression induced by oestradiol deprivation of the ovary in pseudopregnant rabbits
-
Hesla J.S., Miyazaki T., Dasko L.M., Wallach E.E., Dharmarajan A.M. Superoxide dismutase activity, lipid peroxide production and corpus luteum steroidogenesis during natural luteolysis and regression induced by oestradiol deprivation of the ovary in pseudopregnant rabbits. J. Reprod. Fertil. 95:1992;915-924.
-
(1992)
J. Reprod. Fertil.
, vol.95
, pp. 915-924
-
-
Hesla, J.S.1
Miyazaki, T.2
Dasko, L.M.3
Wallach, E.E.4
Dharmarajan, A.M.5
-
49
-
-
0029609021
-
Related articles increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: Possible involvement of apoptosis
-
LeBlanc A. Related articles increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis. J. Neurosci. 15:1995;7837-7846.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7837-7846
-
-
LeBlanc, A.1
-
50
-
-
0034720686
-
Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain
-
Petanceska S.S., Nagy V., Frail D., Gandy S. Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain. Neurology. 54:(12):2000;2212-2217.
-
(2000)
Neurology
, vol.54
, Issue.12
, pp. 2212-2217
-
-
Petanceska, S.S.1
Nagy, V.2
Frail, D.3
Gandy, S.4
-
51
-
-
0031946864
-
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides
-
Xu H., Gouras G.K., Greenfield J.P., Vincent B., Naslund J., Mazzarelli L., Fried G., Jovanovic J.N., Seeger M., Relkin N.R., Liao F., Checler F., Buxbaum J.D., Chait B.T., Thinakaran G., Sisodia S.S., Wang R., Greengard P., Gandy S. Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nat. Med. 4:1998;447-451.
-
(1998)
Nat. Med.
, vol.4
, pp. 447-451
-
-
Xu, H.1
Gouras, G.K.2
Greenfield, J.P.3
Vincent, B.4
Naslund, J.5
Mazzarelli, L.6
Fried, G.7
Jovanovic, J.N.8
Seeger, M.9
Relkin, N.R.10
Liao, F.11
Checler, F.12
Buxbaum, J.D.13
Chait, B.T.14
Thinakaran, G.15
Sisodia, S.S.16
Wang, R.17
Greengard, P.18
Gandy, S.19
-
52
-
-
0026663993
-
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
-
Milward E.A., Papadopoulos R., Fuller S.J., Moir R.D. R.D., Small D., Beyreuther K., Masters C.L. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron. 9:1992;129-137.
-
(1992)
Neuron
, vol.9
, pp. 129-137
-
-
Milward, E.A.1
Papadopoulos, R.2
Fuller, S.J.3
Moir, R.D.R.D.4
Small, D.5
Beyreuther, K.6
Masters, C.L.7
-
53
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
-
Kamal A., Almenar-Queralt A., LeBlanc J.F., Roberts E.A., Goldstein L.S. Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature. 414:2001;643-648.
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
54
-
-
0034733705
-
Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc
-
Cuajungco M.P., Goldstein L.E., Nunomura A., Smith M.A., Lim J.T., Atwood C.S., Huang X., Farrag Y.W., Perry G., Bush A.I. Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc. J. Biol. Chem. 275:2000;19439-19442.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19439-19442
-
-
Cuajungco, M.P.1
Goldstein, L.E.2
Nunomura, A.3
Smith, M.A.4
Lim, J.T.5
Atwood, C.S.6
Huang, X.7
Farrag, Y.W.8
Perry, G.9
Bush, A.I.10
-
55
-
-
0033397009
-
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome
-
Nunomura A., Perry G., Hirai K., Aliev G., Takeda A., Chiba S., Smith M.A. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann. N. Y. Acad. Sci. 893:1999;362-364.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.893
, pp. 362-364
-
-
Nunomura, A.1
Perry, G.2
Hirai, K.3
Aliev, G.4
Takeda, A.5
Chiba, S.6
Smith, M.A.7
-
57
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue L.F., Kuo Y.M., Roher A.E., Brachova L., Shen Y., Sue L., Beach T., Kurth J.H., Rydel R.E., Rogers J. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am. J. Pathol. 155:1999;853-862.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
Beach, T.7
Kurth, J.H.8
Rydel, R.E.9
Rogers, J.10
-
59
-
-
0032557425
-
Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis
-
Atwood C.S., Huang X., Moir R.D., Bacarra N.M., Romano D., Tanzi R.E., Bush A.I. Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis. J. Biol. Chem. 273:1998;12817-12826.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Huang, X.2
Moir, R.D.3
Bacarra, N.M.4
Romano, D.5
Tanzi, R.E.6
Bush, A.I.7
-
60
-
-
0035209719
-
Resistance of human cerebrospinal fluid to in vitro oxidation is directly related to its amyloid-beta content
-
Kontush A., Donarski N., Beisiegel U. Resistance of human cerebrospinal fluid to in vitro oxidation is directly related to its amyloid-beta content. Free Radic. Res. 35:2001;507-517.
-
(2001)
Free Radic. Res.
, vol.35
, pp. 507-517
-
-
Kontush, A.1
Donarski, N.2
Beisiegel, U.3
-
61
-
-
0027482350
-
Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury
-
Gentleman S.M., Nash M.J., Sweeting C.J., Graham D.I., Roberts G.W. Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci. Lett. 160:1993;139-144.
-
(1993)
Neurosci. Lett.
, vol.160
, pp. 139-144
-
-
Gentleman, S.M.1
Nash, M.J.2
Sweeting, C.J.3
Graham, D.I.4
Roberts, G.W.5
-
62
-
-
0027278450
-
Molecular pathology of head trauma: Altered beta APP metabolism and the aetiology of Alzheimer's disease
-
Gentleman S.M., Graham D.I., Roberts G.W. Molecular pathology of head trauma: altered beta APP metabolism and the aetiology of Alzheimer's disease. Prog. Brain Res. 96:1993;237-246.
-
(1993)
Prog. Brain Res.
, vol.96
, pp. 237-246
-
-
Gentleman, S.M.1
Graham, D.I.2
Roberts, G.W.3
-
63
-
-
0031741753
-
Traumatic brain injury increases beta-amyloid peptide 1-42 in cerebrospinal fluid
-
Raby C.A., Morganti-Kossmann M.C., Kossmann T., Stahel P.F., Watson M.D., Evans L.M., Mehta P.D., Spiegel K., Kuo Y.M., Roher A.E., Emmerling M.R. Traumatic brain injury increases beta-amyloid peptide 1-42 in cerebrospinal fluid. J. Neurochem. 71:1998;2505-2509.
-
(1998)
J. Neurochem.
, vol.71
, pp. 2505-2509
-
-
Raby, C.A.1
Morganti-Kossmann, M.C.2
Kossmann, T.3
Stahel, P.F.4
Watson, M.D.5
Evans, L.M.6
Mehta, P.D.7
Spiegel, K.8
Kuo, Y.M.9
Roher, A.E.10
Emmerling, M.R.11
-
64
-
-
0030612292
-
A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury
-
Gentleman S.M., Greenberg B.D., Savage M.J., Noori M., Newman S.J., Roberts G.W., Griffin W.S., Graham D.I. A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury. Neuroreport. 8:1997;1519-1522.
-
(1997)
Neuroreport
, vol.8
, pp. 1519-1522
-
-
Gentleman, S.M.1
Greenberg, B.D.2
Savage, M.J.3
Noori, M.4
Newman, S.J.5
Roberts, G.W.6
Griffin, W.S.7
Graham, D.I.8
-
66
-
-
0037436022
-
Cerebral hemorrhage and amyloid-beta
-
Atwood C.S., Perry G., Smith M.A., Pfeifer M., Boncristiano S., Bondolfi L., Stalder A., Deller T., Staufenbiel M., Mathews P.M., Jucker M. Cerebral hemorrhage and amyloid-beta. Science. 299:2003;1014.
-
(2003)
Science
, vol.299
, pp. 1014
-
-
Atwood, C.S.1
Perry, G.2
Smith, M.A.3
Pfeifer, M.4
Boncristiano, S.5
Bondolfi, L.6
Stalder, A.7
Deller, T.8
Staufenbiel, M.9
Mathews, P.M.10
Jucker, M.11
-
67
-
-
0033844944
-
Characterization of copper interactions with Alzheimer amyloid beta peptides: Identification of an attomolar-affinity copper binding site on amyloid beta1-42
-
Atwood C.S., Scarpa R.C., Huang X., Moir R.D., Jones W.D., Fairlie D.P., Tanzi R.E., Bush A.I. Characterization of copper interactions with Alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. J. Neurochem. 75:2000;1219-1233.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1219-1233
-
-
Atwood, C.S.1
Scarpa, R.C.2
Huang, X.3
Moir, R.D.4
Jones, W.D.5
Fairlie, D.P.6
Tanzi, R.E.7
Bush, A.I.8
-
68
-
-
0034643831
-
Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes
-
Miura T., Suzuki K., Kohata N., Takeuchi H. Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes. Biochemistry. 39:2000;7024-7031.
-
(2000)
Biochemistry
, vol.39
, pp. 7024-7031
-
-
Miura, T.1
Suzuki, K.2
Kohata, N.3
Takeuchi, H.4
-
69
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
Curtain C.C., Ali F., Volitakis I., Cherny R.A., Norton R.S., Beyreuther K., Barrow C.J., Masters C.L., Bush A.I., Barnham K.J. Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J. Biol. Chem. 276:2001;20466-20473.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
Cherny, R.A.4
Norton, R.S.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Bush, A.I.9
Barnham, K.J.10
-
70
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell M.A., Robertson J.D., Teesdale W.J., Campbell J.L., Markesbery W.R. Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158:1998;47-52.
-
(1998)
J. Neurol. Sci.
, vol.158
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
71
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
72
-
-
0346106076
-
Metal binding and oxidation of amyloid-β within isolated senile plaque cores: Raman microscopic evidence
-
Dong J., Atwood C.S., Anderson V.E., Siedlak S.L., Perry G., Smith M.A., Carey P.R. Metal binding and oxidation of amyloid-β within isolated senile plaque cores: raman microscopic evidence. Biochemistry. 42:2003;2768-2773.
-
(2003)
Biochemistry
, vol.42
, pp. 2768-2773
-
-
Dong, J.1
Atwood, C.S.2
Anderson, V.E.3
Siedlak, S.L.4
Perry, G.5
Smith, M.A.6
Carey, P.R.7
-
74
-
-
0027980901
-
Rapid induction of Alzheimer A beta amyloid formation by zinc
-
Bush A.I., Pettingell W.H., Multhau G., Paradis M., Vonsattel J.P., Gusella J.F., Beyreuther K., Masters C.L., Tanzi R.E. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science. 265:1994;1464-1467.
-
(1994)
Science
, vol.265
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhau, G.3
Paradis, M.4
Vonsattel, J.P.5
Gusella, J.F.6
Beyreuther, K.7
Masters, C.L.8
Tanzi, R.E.9
-
75
-
-
0030704680
-
Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors
-
Huang X., Atwood C.S., Moir R.D., Hartshorn M.A., Vonsattel J.P., Tanzi R.E., Bush A.I. Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors. J. Biol. Chem. 272:1997;26464-26470.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26464-26470
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Vonsattel, J.P.5
Tanzi, R.E.6
Bush, A.I.7
-
76
-
-
0035943640
-
New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity
-
Yoshiike Y., Tanemura K., Murayama O., Akagi T., Murayama M., Sato S., Sun X., Tanaka N., Takashima A. New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity. J. Biol. Chem. 276:2001;32293-32299.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32293-32299
-
-
Yoshiike, Y.1
Tanemura, K.2
Murayama, O.3
Akagi, T.4
Murayama, M.5
Sato, S.6
Sun, X.7
Tanaka, N.8
Takashima, A.9
-
77
-
-
0025853543
-
Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis
-
Johnstone E.M., Chaney M.O., Norris F.H., Pascual R., Little S.P. Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis. Brain Res. Mol. Brain Res. 10:1991;299-305.
-
(1991)
Brain Res. Mol. Brain Res.
, vol.10
, pp. 299-305
-
-
Johnstone, E.M.1
Chaney, M.O.2
Norris, F.H.3
Pascual, R.4
Little, S.P.5
-
78
-
-
0033587478
-
Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease
-
Liu S.T., Howlett G., Barrow C.J. Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease. Biochemistry. 38:1999;9373-9378.
-
(1999)
Biochemistry
, vol.38
, pp. 9373-9378
-
-
Liu, S.T.1
Howlett, G.2
Barrow, C.J.3
-
80
-
-
0033551782
-
Aqueous dissolution of Alzheimer's disease Aβ amyloid deposits by biometal depletion
-
Cherny R.A., Legg J.T., McLean C.A., Fairlie D.P., Huang X., Atwood C.S., Beyreuther K., Tanzi R.E., Masters C.L., Bush A.I. Aqueous dissolution of Alzheimer's disease Aβ amyloid deposits by biometal depletion. J. Biol. Chem. 274:1999;23223-23228.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23223-23228
-
-
Cherny, R.A.1
Legg, J.T.2
McLean, C.A.3
Fairlie, D.P.4
Huang, X.5
Atwood, C.S.6
Beyreuther, K.7
Tanzi, R.E.8
Masters, C.L.9
Bush, A.I.10
-
81
-
-
0021253173
-
Evidence that copper-amino acid complexes are potent stimulators of the release of luteinizing hormone-releasing hormone from isolated hypothalamic granules
-
Barnea A., Cho G. Evidence that copper-amino acid complexes are potent stimulators of the release of luteinizing hormone-releasing hormone from isolated hypothalamic granules. Endocrinology. 115:1984;936-943.
-
(1984)
Endocrinology
, vol.115
, pp. 936-943
-
-
Barnea, A.1
Cho, G.2
-
82
-
-
0021287299
-
Release of endogenous Zn2+ from brain tissue during activity
-
Assaf S.Y., Chung S.H. Release of endogenous Zn2+ from brain tissue during activity. Nature. 308:1984;734-736.
-
(1984)
Nature
, vol.308
, pp. 734-736
-
-
Assaf, S.Y.1
Chung, S.H.2
-
83
-
-
0021220724
-
Stimulation-induced uptake and release of zinc in hippocampal slices
-
Howell G.A., Welch M.G., Frederickson C.J. Stimulation-induced uptake and release of zinc in hippocampal slices. Nature. 308:1984;736-738.
-
(1984)
Nature
, vol.308
, pp. 736-738
-
-
Howell, G.A.1
Welch, M.G.2
Frederickson, C.J.3
-
84
-
-
0033515564
-
Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides
-
Dikalov S.I., Vitek M.P., Maples K.R., Mason R.P. Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J. Biol. Chem. 274:1999;9392-9399.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9392-9399
-
-
Dikalov, S.I.1
Vitek, M.P.2
Maples, K.R.3
Mason, R.P.4
-
85
-
-
18344414746
-
The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X., Atwood C.S., Hartshorn M.A., Multhaup G., Goldstein L.E., Scarpa R.C., Cuajungco M.P., Gray D.N., Lim J., Moir R.D., Tanzi R.E., Bush A.I. The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemisty. 38:1999;7609-7616.
-
(1999)
Biochemisty
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
86
-
-
0033601338
-
Alzheimer Aβ interaction with Cu(II) induces neurotoxicity, radicalization, metal reduction and hydrogen peroxide formation
-
Huang X., Cuajungco M.P., Atwood C.S., Hartshorn M.A., Tyndall J., Hanson G.R., Stokes K.C., Multhaup G., Goldstein L.E., Scarpa R.C., Saunders A.J., Lim J., Moir R.D., Glabe C., Bowden E.F., Masters C.L., Fairlie D.P., Tanzi R.E., Bush A.I. Alzheimer Aβ interaction with Cu(II) induces neurotoxicity, radicalization, metal reduction and hydrogen peroxide formation. J. Biol. Chem. 274:1999;37111-37116.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.5
Hanson, G.R.6
Stokes, K.C.7
Multhaup, G.8
Goldstein, L.E.9
Scarpa, R.C.10
Saunders, A.J.11
Lim, J.12
Moir, R.D.13
Glabe, C.14
Bowden, E.F.15
Masters, C.L.16
Fairlie, D.P.17
Tanzi, R.E.18
Bush, A.I.19
-
87
-
-
0036598956
-
Amyloid peptide enhances nail rusting: Novel insight into mechanisms of aging and Alzheimer's disease
-
Mattson M.P., Mattson E.P. Amyloid peptide enhances nail rusting: novel insight into mechanisms of aging and Alzheimer's disease. Ageing Res. Rev. 1:2002;327-330.
-
(2002)
Ageing Res. Rev.
, vol.1
, pp. 327-330
-
-
Mattson, M.P.1
Mattson, E.P.2
-
88
-
-
12644264304
-
Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C
-
Walter J., Grunberg J., Capell A., Pesold B., Schindzielorz A., Citron M., Mendla K., St. George-Hyslop P., Multhaup G., Selkoe D.J., Haass C. Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C. Proc. Natl. Acad. Sci. USA. 94:1997;5349-5354.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5349-5354
-
-
Walter, J.1
Grunberg, J.2
Capell, A.3
Pesold, B.4
Schindzielorz, A.5
Citron, M.6
Mendla, K.7
St. George-Hyslop, P.8
Multhaup, G.9
Selkoe, D.J.10
Haass, C.11
-
89
-
-
0033860372
-
Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity
-
Review
-
Varadarajan S., Yatin S., Aksenova M., Butterfield D.A. Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. J. Struct. Biol. 130:2000;184-208. Review.
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 184-208
-
-
Varadarajan, S.1
Yatin, S.2
Aksenova, M.3
Butterfield, D.A.4
-
90
-
-
0032604157
-
Biological chemistry of copper-zinc superoxide dismutase and its link to amyotrophic lateral sclerosis
-
Lyons T.J., Gralla E.B., Valentine J.S. Biological chemistry of copper-zinc superoxide dismutase and its link to amyotrophic lateral sclerosis. Metal Ions Biol. Systems. 36:1999;125-177.
-
(1999)
Metal Ions Biol. Systems
, vol.36
, pp. 125-177
-
-
Lyons, T.J.1
Gralla, E.B.2
Valentine, J.S.3
-
91
-
-
0003021329
-
Alzheimer Aβ functions as a superoxide antioxidant in vitro and in vivo
-
Bush A.I., Lynch T., Cherny R.C., Atwood C.S., Goldstein L.E., Moir R.D., Li Q.-X., Cabelli D.E., Multhaup G., Masters C.L., Tanzi R.E., Huang X. Alzheimer Aβ functions as a superoxide antioxidant in vitro and in vivo. Soc. Neurosci. Abstr. 25:1999;14.
-
(1999)
Soc. Neurosci. Abstr.
, vol.25
, pp. 14
-
-
Bush, A.I.1
Lynch, T.2
Cherny, R.C.3
Atwood, C.S.4
Goldstein, L.E.5
Moir, R.D.6
Li, Q.-X.7
Cabelli, D.E.8
Multhaup, G.9
Masters, C.L.10
Tanzi, R.E.11
Huang, X.12
-
92
-
-
0000078126
-
Anti-apoptotic action of Alzheimer Aβ
-
Chan C.-W., Dharmarajan A., Atwood C.S., Huang X., Tanzi R.E., Bush A.I., Martins R.N. Anti-apoptotic action of Alzheimer Aβ Alzheimer's Reports. 2:1999;1-6.
-
(1999)
Alzheimer's Reports
, vol.2
, pp. 1-6
-
-
Chan, C.-W.1
Dharmarajan, A.2
Atwood, C.S.3
Huang, X.4
Tanzi, R.E.5
Bush, A.I.6
Martins, R.N.7
-
93
-
-
0029863551
-
Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger
-
Tomiyama T., Shoji A., Kataoka K., Suwa Y., Asano S., Kaneko H., Endo N. Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger. J. Biol. Chem. 271:1996;6839-6844.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6839-6844
-
-
Tomiyama, T.1
Shoji, A.2
Kataoka, K.3
Suwa, Y.4
Asano, S.5
Kaneko, H.6
Endo, N.7
-
94
-
-
0028085940
-
Antioxidant potential of anaerobic human plasma: Role of serum albumin and thiols as scavengers of carbon radicals
-
Soriani M., Pietraforte D., Minetti M. Antioxidant potential of anaerobic human plasma: role of serum albumin and thiols as scavengers of carbon radicals. Arch. Biochem. Biophys. 312:1994;180-188.
-
(1994)
Arch. Biochem. Biophys.
, vol.312
, pp. 180-188
-
-
Soriani, M.1
Pietraforte, D.2
Minetti, M.3
-
95
-
-
0031127537
-
Physiological thiol compounds exert pro- and anti-oxidant effects, respectively, on iron- and copper-dependent oxidation of human low-density lipoprotein
-
Lynch S.M., Frei B. Physiological thiol compounds exert pro- and anti-oxidant effects, respectively, on iron- and copper-dependent oxidation of human low-density lipoprotein. Biochim. Biophys. Acta. 1345:1997;215-221.
-
(1997)
Biochim. Biophys. Acta
, vol.1345
, pp. 215-221
-
-
Lynch, S.M.1
Frei, B.2
-
97
-
-
0033529417
-
Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis
-
Kaltschmidt B., Uherek M., Wellmann H., Volk B., Kaltschmidt C. Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis. Proc. Natl. Acad. Sci. USA. 96:1999;9409-9414.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9409-9414
-
-
Kaltschmidt, B.1
Uherek, M.2
Wellmann, H.3
Volk, B.4
Kaltschmidt, C.5
-
98
-
-
0027288860
-
Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth
-
Koo E.H., Park L., Selkoe D.J. Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth. Proc. Natl. Acad. Sci. USA. 90:1993;4748-4752.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4748-4752
-
-
Koo, E.H.1
Park, L.2
Selkoe, D.J.3
-
99
-
-
0030592575
-
Physiological levels of beta-amyloid peptide promote PC12 cell proliferation
-
Luo Y., Sunderland T., Roth G.S., Wolozin B. Physiological levels of beta-amyloid peptide promote PC12 cell proliferation. Neurosci. Lett. 217:1996;125-128.
-
(1996)
Neurosci. Lett.
, vol.217
, pp. 125-128
-
-
Luo, Y.1
Sunderland, T.2
Roth, G.S.3
Wolozin, B.4
-
100
-
-
0033982030
-
Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures
-
Postuma R.B., He W., Nunan J., Beyreuther K., Masters C.L., Barrow C.J., Small D.H. Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures. J. Neurochem. 74:2000;1122-1130.
-
(2000)
J. Neurochem.
, vol.74
, pp. 1122-1130
-
-
Postuma, R.B.1
He, W.2
Nunan, J.3
Beyreuther, K.4
Masters, C.L.5
Barrow, C.J.6
Small, D.H.7
-
101
-
-
0027932162
-
Effect of substance P and protein kinase inhibitors on beta-amyloid peptide-induced proliferation of cultured brain cells
-
Singh V.K., Cheng J.F., Leu S.J. Effect of substance P and protein kinase inhibitors on beta-amyloid peptide-induced proliferation of cultured brain cells. Brain Res. 660:1994;353-356.
-
(1994)
Brain Res.
, vol.660
, pp. 353-356
-
-
Singh, V.K.1
Cheng, J.F.2
Leu, S.J.3
-
102
-
-
0026646280
-
Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat
-
Stephenson D.T., Rash K., Clemens J.A. Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat. Brain Res. 593:1992;128-135.
-
(1992)
Brain Res.
, vol.593
, pp. 128-135
-
-
Stephenson, D.T.1
Rash, K.2
Clemens, J.A.3
-
103
-
-
0029141049
-
Trophic effects of substance P and beta-amyloid peptide on dibutyryl cyclic AMP-differentiated human leukemic (HL-60) cells
-
Takenouchi T., Munekata E. Trophic effects of substance P and beta-amyloid peptide on dibutyryl cyclic AMP-differentiated human leukemic (HL-60) cells. Life Sci. 56:1995;PL479-484.
-
(1995)
Life Sci.
, vol.56
, pp. 479-484
-
-
Takenouchi, T.1
Munekata, E.2
-
104
-
-
0024543836
-
Amyloid beta protein enhances the survival of hippocampal neurons in vitro
-
Whitson J.S., Selkoe D.J., Cotman C.W. Amyloid beta protein enhances the survival of hippocampal neurons in vitro. Science. 243:1989;1488-1490.
-
(1989)
Science
, vol.243
, pp. 1488-1490
-
-
Whitson, J.S.1
Selkoe, D.J.2
Cotman, C.W.3
-
105
-
-
0025095256
-
Beta-amyloid protein promotes neuritic branching in hippocampal cultures
-
Whitson J.S., Glabe C.G., Shintani E., Abcar A., Cotman C.W. Beta-amyloid protein promotes neuritic branching in hippocampal cultures. Neurosci. Lett. 110:1990;319-324.
-
(1990)
Neurosci. Lett.
, vol.110
, pp. 319-324
-
-
Whitson, J.S.1
Glabe, C.G.2
Shintani, E.3
Abcar, A.4
Cotman, C.W.5
-
106
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
-
Yankner B.A., Duffy L.K., Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science. 250:1990;279-282.
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
107
-
-
0035178803
-
Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma
-
Kontush A., Berndt C., Weber W., Akopyan V., Arlt S., Schippling S., Beisiegel U. Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma. Free Radic. Biol. Med. 30:(1):2001;119-128.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, Issue.1
, pp. 119-128
-
-
Kontush, A.1
Berndt, C.2
Weber, W.3
Akopyan, V.4
Arlt, S.5
Schippling, S.6
Beisiegel, U.7
-
108
-
-
0037096251
-
A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage
-
Zou K., Gong J.S., Yanagisawa K., Michikawa M. A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage. J. Neurosci. 22:2002;4833-4841.
-
(2002)
J. Neurosci.
, vol.22
, pp. 4833-4841
-
-
Zou, K.1
Gong, J.S.2
Yanagisawa, K.3
Michikawa, M.4
-
109
-
-
0033794471
-
Factors affecting pro- and anti-oxidant properties of fragments of the β-protein precursor (βPP): Implication for Alzheimer's disease
-
Andorn A.C., Kalaria R.N. Factors affecting pro- and anti-oxidant properties of fragments of the β-protein precursor (βPP): implication for Alzheimer's disease. J. Alzheimer's Dis. 2:2000;69-78.
-
(2000)
J. Alzheimer's Dis.
, vol.2
, pp. 69-78
-
-
Andorn, A.C.1
Kalaria, R.N.2
-
110
-
-
0034670134
-
Differential alterations in antioxidant capacity in cells from Alzheimer patients
-
Gibson G.E., Zhang H., Sheu K.R., Park L.C. Differential alterations in antioxidant capacity in cells from Alzheimer patients. Biochim. Biophys. Acta. 1502:2000;319-329.
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 319-329
-
-
Gibson, G.E.1
Zhang, H.2
Sheu, K.R.3
Park, L.C.4
-
111
-
-
0032400818
-
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis
-
Bursztajn S., DeSouza R., McPhie D.L., Berman S.A., et al. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. J. Neurosci. 18:1998;9790-9799.
-
(1998)
J. Neurosci.
, vol.18
, pp. 9790-9799
-
-
Bursztajn, S.1
DeSouza, R.2
McPhie, D.L.3
Berman, S.A.4
-
112
-
-
0034613438
-
Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations
-
Leutner S., Czech C., Schindowski K., Touchet N., Eckert A., Muller W.E. Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations. Neurosci. Lett. 292:2000;87-90.
-
(2000)
Neurosci. Lett.
, vol.292
, pp. 87-90
-
-
Leutner, S.1
Czech, C.2
Schindowski, K.3
Touchet, N.4
Eckert, A.5
Muller, W.E.6
-
113
-
-
0031824782
-
Aging renders the brain vulnerable to amyloid β-protein neurotoxicity
-
Geula C., Wu C.K., Saroff D., Lorenzo A., Yuan M., Yankner B.A. Aging renders the brain vulnerable to amyloid β-protein neurotoxicity. Nat. Med. 4:1998;827-831.
-
(1998)
Nat. Med.
, vol.4
, pp. 827-831
-
-
Geula, C.1
Wu, C.K.2
Saroff, D.3
Lorenzo, A.4
Yuan, M.5
Yankner, B.A.6
-
115
-
-
0037388672
-
Deposits of fibrillar Aβ do not cause neuronal loss or ferritin expression in adult rat brain
-
Bishop G.M., Robinson S.R. Deposits of fibrillar Aβ do not cause neuronal loss or ferritin expression in adult rat brain. J. Neural Transm. 110:2003;381-400.
-
(2003)
J. Neural Transm.
, vol.110
, pp. 381-400
-
-
Bishop, G.M.1
Robinson, S.R.2
-
116
-
-
0000447492
-
β-Amyloid helps to protect neurons from oxidative stress
-
Bishop G.M., Robinson S.R. β-Amyloid helps to protect neurons from oxidative stress. Neurobiol. Aging. 21:(Suppl. 1S):2000;S226.
-
(2000)
Neurobiol. Aging
, vol.21
, Issue.SUPPL. 1S
, pp. 226
-
-
Bishop, G.M.1
Robinson, S.R.2
-
117
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo Q., Fu W., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat. Med. 5:1999;101-106.
-
(1999)
Nat. Med.
, vol.5
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
118
-
-
0033009194
-
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: Central roles of superoxide production and caspase activation
-
Guo Q., Sebastian L., Sopher B.L., Miller M.W., Ware C.B., Martin G.M., Mattson M.P. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. J. Neurochem. 72:1999;1019-1029.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1019-1029
-
-
Guo, Q.1
Sebastian, L.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
119
-
-
0029992521
-
The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity
-
Lonnrot K., Metsa-Ketela T., Molnar G., Ahonen J.P., Latvala M., Peltola J., Pietila T., Alho H. The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity. Free Radic. Biol. Med. 21:1996;211-217.
-
(1996)
Free Radic. Biol. Med.
, vol.21
, pp. 211-217
-
-
Lonnrot, K.1
Metsa-Ketela, T.2
Molnar, G.3
Ahonen, J.P.4
Latvala, M.5
Peltola, J.6
Pietila, T.7
Alho, H.8
-
120
-
-
0000128256
-
Neuronal cell cultures protect low density lipoprotein from oxidation
-
Berndt C., Kontush A., Beisiegel U. Neuronal cell cultures protect low density lipoprotein from oxidation. Neurobiol. Aging. 19:1998;S284.
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 284
-
-
Berndt, C.1
Kontush, A.2
Beisiegel, U.3
-
121
-
-
0033973597
-
Presence of CuZn superoxide dismutase in human serum lipoproteins
-
Mondola P., Bifulco M., Seru R., Annella T., Ciriolo M.R., Santillo M. Presence of CuZn superoxide dismutase in human serum lipoproteins. FEBS Lett. 467:(No. 1):2000;57-60.
-
(2000)
FEBS Lett.
, vol.467
, Issue.1
, pp. 57-60
-
-
Mondola, P.1
Bifulco, M.2
Seru, R.3
Annella, T.4
Ciriolo, M.R.5
Santillo, M.6
-
122
-
-
0030965850
-
Peptides in membranes: Tipping the balance of membrane stability
-
Review
-
Brasseur R., Pillot T., Lins L., Vandekerckhove J., Rosseneu M. Peptides in membranes: tipping the balance of membrane stability. Trends Biochem. Sci. 22:1997;167-171. Review.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 167-171
-
-
Brasseur, R.1
Pillot, T.2
Lins, L.3
Vandekerckhove, J.4
Rosseneu, M.5
-
123
-
-
0028609448
-
The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma
-
Koudinov A., Matsubara E., Franione B., Ghiso J. The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem. Biophys. Res. Commun. 205:1994;1164-1171.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.205
, pp. 1164-1171
-
-
Koudinov, A.1
Matsubara, E.2
Franione, B.3
Ghiso, J.4
-
124
-
-
0030601055
-
Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: Association with high density lipoproteins
-
Koudinov A.R., Koudinova N.V., Kumar A., Beavis R.C., Ghiso J. Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins. Biochem. Biophys. Res. Commun. 223:1996;592-597.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.223
, pp. 592-597
-
-
Koudinov, A.R.1
Koudinova, N.V.2
Kumar, A.3
Beavis, R.C.4
Ghiso, J.5
-
125
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
Simons M., Keller P., De Strooper B., Beyreuther K., Dotti C.G., Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. USA. 95:1998;6460-6464.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
126
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
Sparks D.L., Scheff S.W., Hunsaker J.C. 3rd, Liu H., Landers T., Gross D.R. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp. Neurol. 126:1994;88-94.
-
(1994)
Exp. Neurol.
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker J.C. III3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
127
-
-
0035160066
-
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Refolo L.M., Pappolla M.A., LaFrancois J., Malester B., Schmidt S.D., Thomas-Bryant T., Tint G.S., Wang R., Mercken M., Petanceska S.S., Duff K.E. A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 8:2001;890-899.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 890-899
-
-
Refolo, L.M.1
Pappolla, M.A.2
LaFrancois, J.3
Malester, B.4
Schmidt, S.D.5
Thomas-Bryant, T.6
Tint, G.S.7
Wang, R.8
Mercken, M.9
Petanceska, S.S.10
Duff, K.E.11
-
128
-
-
0035830844
-
Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-Pick type C cells
-
Yamazaki T., Chang T.Y., Haass C., Ihara Y. Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-Pick type C cells. J. Biol. Chem. 276:2001;4454-4460.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4454-4460
-
-
Yamazaki, T.1
Chang, T.Y.2
Haass, C.3
Ihara, Y.4
-
129
-
-
0029070173
-
Differential effects of amyloid peptides β-(1-40) and β-(25-35) injections into the rat nucleus basalis
-
Giovannelli L., Casamenti F., Scali C., Bartolini L., Pepeu G. Differential effects of amyloid peptides β-(1-40) and β-(25-35) injections into the rat nucleus basalis. Neuroscience. 66:1995;781-792.
-
(1995)
Neuroscience
, vol.66
, pp. 781-792
-
-
Giovannelli, L.1
Casamenti, F.2
Scali, C.3
Bartolini, L.4
Pepeu, G.5
-
130
-
-
0032551649
-
Long-term changes in the aggregation state and toxic effects of β-amyloid injected into the rat brain
-
Giovannelli L., Scali C., Faussone-Pellegrini M.S., Pepeu G., Casamenti F. Long-term changes in the aggregation state and toxic effects of β-amyloid injected into the rat brain. Neuroscience. 87:1998;349-357.
-
(1998)
Neuroscience
, vol.87
, pp. 349-357
-
-
Giovannelli, L.1
Scali, C.2
Faussone-Pellegrini, M.S.3
Pepeu, G.4
Casamenti, F.5
-
131
-
-
0031974406
-
Microglial response to amyloid plaques in APPsw transgenic mice
-
Frautschy S.A., Yang F., Irrizarry M., Hyman B., Saido T.C., Hsiao K., Cole G.M. Microglial response to amyloid plaques in APPsw transgenic mice. Am. J. Pathol. 152:1998;307-317.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 307-317
-
-
Frautschy, S.A.1
Yang, F.2
Irrizarry, M.3
Hyman, B.4
Saido, T.C.5
Hsiao, K.6
Cole, G.M.7
-
132
-
-
0033991657
-
Aβ and perlecan in rat brain: Glial activation, gradual clearance and limited neurotoxicity
-
Holcomb L.A., Gordon M.N., Benkovic S.A., Morgan D.G. Aβ and perlecan in rat brain: glial activation, gradual clearance and limited neurotoxicity. Mech. Ageing Dev. 112:2000;135-152.
-
(2000)
Mech. Ageing Dev.
, vol.112
, pp. 135-152
-
-
Holcomb, L.A.1
Gordon, M.N.2
Benkovic, S.A.3
Morgan, D.G.4
-
133
-
-
0000801077
-
High levels of microglial iron in the cortices of old primates: Implications for the neurotoxicity of β-amyloid
-
Fox S.R., Bishop G.M., Robinson S.R. High levels of microglial iron in the cortices of old primates: implications for the neurotoxicity of β-amyloid. Proc. Aust. Neurosci. Soc. 10:1999;213.
-
(1999)
Proc. Aust. Neurosci. Soc.
, vol.10
, pp. 213
-
-
Fox, S.R.1
Bishop, G.M.2
Robinson, S.R.3
-
134
-
-
0026688163
-
Effect of beta amyloid peptides on neurons in hippocampal slice cultures
-
Malouf A.T. Effect of beta amyloid peptides on neurons in hippocampal slice cultures. Neurobiol. Aging. 13:1992;543-551.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 543-551
-
-
Malouf, A.T.1
-
135
-
-
0025733411
-
Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures
-
Pike C.J., Walencewicz A.J., Glabe C.G., Cotman C.W. Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. Eur. J. Pharmacol. 207:1991;367-368.
-
(1991)
Eur. J. Pharmacol.
, vol.207
, pp. 367-368
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
136
-
-
0027447286
-
Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
-
Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13:1993;1676-1687.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
137
-
-
0028265912
-
Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro
-
Simmons L.K., May P.C., Tomaselli K.J., Rydel R.E., Fuson K.S., Brigham E.F., Wright S., Lieberburg I., Becker G.W., Brems D.N., et al. Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro. Mol. Pharmacol. 45:1994;373-379.
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 373-379
-
-
Simmons, L.K.1
May, P.C.2
Tomaselli, K.J.3
Rydel, R.E.4
Fuson, K.S.5
Brigham, E.F.6
Wright, S.7
Lieberburg, I.8
Becker, G.W.9
Brems, D.N.10
-
138
-
-
0028618190
-
Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid
-
Ueda K., Saitoh T., Mori H. Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. Biochem. Biophys. Res. Commun. 205:1994;1366-1372.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.205
, pp. 1366-1372
-
-
Ueda, K.1
Saitoh, T.2
Mori, H.3
-
139
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., Morgan T.E., Rozovsky I., Trommer B., Viola K.L., Wals P., Zhang C., Finch C.E., Krafft G.A., Klein W.L. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. USA. 95:(11):1998;6448-6453.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
140
-
-
0029670992
-
Deposits of A beta fibrils are not toxic to cortical and hippocampal neurons in vitro
-
Wujek J.R., Dority M.D., Frederickson R.C., Brunden K.R. Deposits of A beta fibrils are not toxic to cortical and hippocampal neurons in vitro. Neurobiol. Aging. 17:1996;107-113.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 107-113
-
-
Wujek, J.R.1
Dority, M.D.2
Frederickson, R.C.3
Brunden, K.R.4
-
142
-
-
0036827161
-
Amyloid beta as a bioflocculant: Implications for the amyloid hypothesis of Alzheimer's disease
-
Robinson S.R., Bishop G.M. Amyloid beta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol. Aging. 23:2002;1051-1072.
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 1051-1072
-
-
Robinson, S.R.1
Bishop, G.M.2
-
143
-
-
0035865905
-
Redox-active iron mediates amyloid-β toxicity
-
Rottkamp C.A., Raina A.K., Zhu X., Gaier E., Bush A.I., Atwood C.S., Chevion M., Perry G., Smith M.A. Redox-active iron mediates amyloid-β toxicity. Free Radic. Biol. Med. 30:2001;447-450.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 447-450
-
-
Rottkamp, C.A.1
Raina, A.K.2
Zhu, X.3
Gaier, E.4
Bush, A.I.5
Atwood, C.S.6
Chevion, M.7
Perry, G.8
Smith, M.A.9
-
144
-
-
0035874024
-
New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps
-
Turnbull S., Tabner B.J., El-Agnaf O.M., Twyman L.J., Allsop D. New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps. Free Radic. Biol. Med. 30:2001;1154-1162.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 1154-1162
-
-
Turnbull, S.1
Tabner, B.J.2
El-Agnaf, O.M.3
Twyman, L.J.4
Allsop, D.5
-
145
-
-
18144453796
-
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
-
DeWitt D.A., Perry G., Cohen M., Doller C., Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp. Neurol. 149:1998;329-340.
-
(1998)
Exp. Neurol.
, vol.149
, pp. 329-340
-
-
DeWitt, D.A.1
Perry, G.2
Cohen, M.3
Doller, C.4
Silver, J.5
-
146
-
-
0030612033
-
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry M.C., McNamara M., Fedorchak K., Hsiao K., Hyman B.T. APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol. 56:1997;965-973.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
Hsiao, K.4
Hyman, B.T.5
-
147
-
-
0030611097
-
Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
-
Irizarry M.C., Soriano F., McNamara M., Page K.J., Schenk D., Games D., Hyman B.T. Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J. Neurosci. 17:1997;7053-7059.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7053-7059
-
-
Irizarry, M.C.1
Soriano, F.2
McNamara, M.3
Page, K.J.4
Schenk, D.5
Games, D.6
Hyman, B.T.7
-
148
-
-
0037197836
-
Tau is essential to beta-amyloid-induced neurotoxicity
-
Rapoport M., Dawson H.N., Binder L.I., Vitek M.P., Ferreira A. Tau is essential to beta-amyloid-induced neurotoxicity. Proc. Natl. Acad. Sci. USA. 99:2002;6364-6369.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
149
-
-
0036358289
-
The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its confirmation, aggregation, and neurotoxic properties
-
Soreghan B., Pike C., Kayed R., Tian W., Milton S., Cotman C., Glabe C.G. The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its confirmation, aggregation, and neurotoxic properties. Neuromolecular Med. 1:2002;81-94.
-
(2002)
Neuromolecular Med.
, vol.1
, pp. 81-94
-
-
Soreghan, B.1
Pike, C.2
Kayed, R.3
Tian, W.4
Milton, S.5
Cotman, C.6
Glabe, C.G.7
-
150
-
-
0026682931
-
Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra
-
Barrow C.J., Yasuda A., Kenny P.T., Zagorski M.G. Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra. J. Mol. Biol. 225:1992;1075-1093.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 1075-1093
-
-
Barrow, C.J.1
Yasuda, A.2
Kenny, P.T.3
Zagorski, M.G.4
-
151
-
-
0026631361
-
NMR studies of amyloid beta-peptides: Proton assignments, secondary structure, and mechanism of an alpha-helix - Beta-sheet conversion for a homologous, 28-residue. N-terminal fragment
-
Zagorski M.G., Barrow C.J. NMR studies of amyloid beta-peptides: proton assignments, secondary structure, and mechanism of an alpha-helix - beta-sheet conversion for a homologous, 28-residue. N-terminal fragment. Biochemistry. 31:(24):1992;5621-5631.
-
(1992)
Biochemistry
, vol.31
, Issue.24
, pp. 5621-5631
-
-
Zagorski, M.G.1
Barrow, C.J.2
-
153
-
-
0025779179
-
Solution structures of beta peptide and its constituent fragments: Relation to amyloid deposition
-
Barrow C.J., Zagorski M.G. Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition. Science. 253:1991;179-182.
-
(1991)
Science
, vol.253
, pp. 179-182
-
-
Barrow, C.J.1
Zagorski, M.G.2
-
154
-
-
0033528666
-
Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations
-
Moir R.D., Atwood C.S., Romano D.M., Laurans M.H., Huang X., Bush A.I., Smith J.D., Tanzi R.E. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. Biochemistry. 38:1999;4595-4603.
-
(1999)
Biochemistry
, vol.38
, pp. 4595-4603
-
-
Moir, R.D.1
Atwood, C.S.2
Romano, D.M.3
Laurans, M.H.4
Huang, X.5
Bush, A.I.6
Smith, J.D.7
Tanzi, R.E.8
-
155
-
-
0032880901
-
Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress
-
Varadarajan S., Yatin S., Kanski J., Jahanshahi F., Butterfield D.A. Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress. Brain Res. Bull. 50:1999;133-141.
-
(1999)
Brain Res. Bull.
, vol.50
, pp. 133-141
-
-
Varadarajan, S.1
Yatin, S.2
Kanski, J.3
Jahanshahi, F.4
Butterfield, D.A.5
-
156
-
-
0034801348
-
Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1-42) and A beta(25-35)
-
Varadarajan S., Kanski J., Aksenova M., Lauderback C., Butterfield D.A. Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1-42) and A beta(25-35). J. Am. Chem. Soc. 123:2001;5625-5631.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 5625-5631
-
-
Varadarajan, S.1
Kanski, J.2
Aksenova, M.3
Lauderback, C.4
Butterfield, D.A.5
-
157
-
-
0030050065
-
A beta (25-35) peptide displays H2O2-like reactivity towards aqueous Fe2+, nitroxide spin probes, and synaptosomal membrane proteins
-
Butterfield D.A., Martin L., Carney J.M., Hensley K. A beta (25-35) peptide displays H2O2-like reactivity towards aqueous Fe2+, nitroxide spin probes, and synaptosomal membrane proteins. Life Sci. 58:1996;217-228.
-
(1996)
Life Sci.
, vol.58
, pp. 217-228
-
-
Butterfield, D.A.1
Martin, L.2
Carney, J.M.3
Hensley, K.4
-
158
-
-
0032514165
-
Promotion of transition metal-induced reactive oxygen species formation by beta-amyloid
-
Bondy S.C., Guo-Ross S.X., Truong A.T. Promotion of transition metal-induced reactive oxygen species formation by beta-amyloid. Brain Res. 799:1998;91-96.
-
(1998)
Brain Res.
, vol.799
, pp. 91-96
-
-
Bondy, S.C.1
Guo-Ross, S.X.2
Truong, A.T.3
-
159
-
-
0028178837
-
Beta-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: Implications to Alzheimer's disease
-
Butterfield D.A., Hensley K., Harris M., Mattson M., Carney J. Beta-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem. Biophys. Res. Commun. 200:1994;710-715.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.200
, pp. 710-715
-
-
Butterfield, D.A.1
Hensley, K.2
Harris, M.3
Mattson, M.4
Carney, J.5
-
160
-
-
0033977413
-
Time-course of oxidation of lipids in human cerebrospinal fluid in vitro
-
Arlt S., Finckh B., Beisiegel U., Kontush A. Time-course of oxidation of lipids in human cerebrospinal fluid in vitro. Free Radic. Res. 32:2000;103-114.
-
(2000)
Free Radic. Res.
, vol.32
, pp. 103-114
-
-
Arlt, S.1
Finckh, B.2
Beisiegel, U.3
Kontush, A.4
-
161
-
-
0031020476
-
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
-
Mark R.J., Lovell M.A., Markesbery W.R., Uchida K., Mattson M.P. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J. Neurochem. 68:1997;255-264.
-
(1997)
J. Neurochem.
, vol.68
, pp. 255-264
-
-
Mark, R.J.1
Lovell, M.A.2
Markesbery, W.R.3
Uchida, K.4
Mattson, M.P.5
-
162
-
-
0034981701
-
Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation
-
Xu J., Chen S., Ku G., Ahmed S.H., Xu J., Chen H., Hsu C.Y. Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation. J. Cereb. Blood Flow Metab. 21:2001;702-710.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 702-710
-
-
Xu, J.1
Chen, S.2
Ku, G.3
Ahmed, S.H.4
Xu, J.5
Chen, H.6
Hsu, C.Y.7
-
163
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
Hensley K., Carney J.M., Mattson M.P., Aksenova M., Harris M., Wu J.F., Floyd R.A., Butterfield D.A. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc. Natl. Acad. Sci. USA. 91:1994;3270-3274.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
164
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell. 77:1994;817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
165
-
-
0028842244
-
Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type
-
Gsell W., Conrad R., Hickethier M., Sofic E., Frolich L., Wichart I., Jellinger K., Moll G., Ransmayr G., Beckmann H., et al. Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type. J. Neurochem. 64:1995;1216-1223.
-
(1995)
J. Neurochem.
, vol.64
, pp. 1216-1223
-
-
Gsell, W.1
Conrad, R.2
Hickethier, M.3
Sofic, E.4
Frolich, L.5
Wichart, I.6
Jellinger, K.7
Moll, G.8
Ransmayr, G.9
Beckmann, H.10
-
166
-
-
0028807137
-
Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation
-
Hensley K., Hall N., Subramaniam R., Cole P., Harris M., Aksenov M., Aksenova M., Gabbita S.P., Wu J.F., Carney J.M., et al. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J. Neurochem. 65:1995;2146-2156.
-
(1995)
J. Neurochem.
, vol.65
, pp. 2146-2156
-
-
Hensley, K.1
Hall, N.2
Subramaniam, R.3
Cole, P.4
Harris, M.5
Aksenov, M.6
Aksenova, M.7
Gabbita, S.P.8
Wu, J.F.9
Carney, J.M.10
-
167
-
-
0029670094
-
Beta-amyloid-mediated vasoactivity and vascular endothelial damage
-
Thomas T., Thomas G., McLendon C., Sutton T., Mullan M. Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 380:1996;168-171.
-
(1996)
Nature
, vol.380
, pp. 168-171
-
-
Thomas, T.1
Thomas, G.2
McLendon, C.3
Sutton, T.4
Mullan, M.5
-
168
-
-
0028916920
-
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium
-
Mattson M.P., Goodman Y. Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium. Brain Res. 676:1995;219-224.
-
(1995)
Brain Res.
, vol.676
, pp. 219-224
-
-
Mattson, M.P.1
Goodman, Y.2
-
169
-
-
0030155860
-
Amyloid beta-peptide and oxidative cellular injury in Alzheimer's disease
-
Mark R.J., Blanc E.M., Mattson M.P. Amyloid beta-peptide and oxidative cellular injury in Alzheimer's disease. Mol. Neurobiol. 12:1996;211-224.
-
(1996)
Mol. Neurobiol.
, vol.12
, pp. 211-224
-
-
Mark, R.J.1
Blanc, E.M.2
Mattson, M.P.3
-
170
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery W.R. Oxidative stress hypothesis in Alzheimer's disease. Free Radic. Biol. Med. 23:(1):1997;134-147.
-
(1997)
Free Radic. Biol. Med.
, vol.23
, Issue.1
, pp. 134-147
-
-
Markesbery, W.R.1
-
171
-
-
0024342769
-
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease
-
Rumble B., Retallack R., Hilbich C., Simms G., Multhaup G., Martins R., Hockey A., Montgomery P., Beyreuther K., Masters C.L. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. New Engl. J. Med. 320:1989;1446-1452.
-
(1989)
New Engl. J. Med.
, vol.320
, pp. 1446-1452
-
-
Rumble, B.1
Retallack, R.2
Hilbich, C.3
Simms, G.4
Multhaup, G.5
Martins, R.6
Hockey, A.7
Montgomery, P.8
Beyreuther, K.9
Masters, C.L.10
-
172
-
-
13344293701
-
Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
-
Teller J.K., Russo C., DeBusk L.M., Angelini G., Zaccheo D., Dagna-Bricarelli F., Scartezzini P., Bertolini S., Mann D.M., Tabaton M., Gambetti P. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nat. Med. 2:1996;93-95.
-
(1996)
Nat. Med.
, vol.2
, pp. 93-95
-
-
Teller, J.K.1
Russo, C.2
DeBusk, L.M.3
Angelini, G.4
Zaccheo, D.5
Dagna-Bricarelli, F.6
Scartezzini, P.7
Bertolini, S.8
Mann, D.M.9
Tabaton, M.10
Gambetti, P.11
-
173
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
Busciglio J., Yankner B.A. Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature. 378:1995;776-779.
-
(1995)
Nature
, vol.378
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
174
-
-
0034035616
-
Metals and neuroscience
-
Bush A.I. Metals and neuroscience. Curr Opin. Chem. Biol. 4:2000;184-191.
-
(2000)
Curr Opin. Chem. Biol.
, vol.4
, pp. 184-191
-
-
Bush, A.I.1
-
175
-
-
0025940313
-
The balance between Cu,Zn-superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress
-
Amstad P., Peskin A., Shah G., Mirault M.E., Moret R., Zbinden I., Cerutti P. The balance between Cu,Zn-superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress. Biochemistry. 30:(38):1991;9305-9313.
-
(1991)
Biochemistry
, vol.30
, Issue.38
, pp. 9305-9313
-
-
Amstad, P.1
Peskin, A.2
Shah, G.3
Mirault, M.E.4
Moret, R.5
Zbinden, I.6
Cerutti, P.7
-
176
-
-
0029980319
-
Characterization of the genomic structure of the mouse APLP1 gene
-
Zhong S., Wu K., Black I.B., Schaar D.G. Characterization of the genomic structure of the mouse APLP1 gene. Genomics. 32:1996;159-162.
-
(1996)
Genomics
, vol.32
, pp. 159-162
-
-
Zhong, S.1
Wu, K.2
Black, I.B.3
Schaar, D.G.4
-
177
-
-
0026469348
-
Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme
-
Sato K., Akaike T., Kohno M., Ando M., Maeda H. Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme. J. Biol. Chem. 267:(35):1992;25371-25377.
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.35
, pp. 25371-25377
-
-
Sato, K.1
Akaike, T.2
Kohno, M.3
Ando, M.4
Maeda, H.5
-
178
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn L.I., Houseweart M.K., Kato S., Anderson K.L., Anderson S.L., Ohama E., Reaume A.G., Scott R.W., Cleveland D.W. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science. 281:1998;1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.L.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
179
-
-
0032514907
-
Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis
-
Goto J.J., Gralla E.B., Valentine J.S., Cabelli D.E. Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis. J. Biol. Chem. 273:1998;30104-30109.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30104-30109
-
-
Goto, J.J.1
Gralla, E.B.2
Valentine, J.S.3
Cabelli, D.E.4
-
180
-
-
0015984199
-
Reduction and inactivation of superoxide dismutase by hydrogen peroxide
-
Bray R.C., Cockle S.A., Fielden E.M., Roberts P.B., Rotillo G., Calabrese L. Reduction and inactivation of superoxide dismutase by hydrogen peroxide. Biochem. J. 139:1974;43-48.
-
(1974)
Biochem. J.
, vol.139
, pp. 43-48
-
-
Bray, R.C.1
Cockle, S.A.2
Fielden, E.M.3
Roberts, P.B.4
Rotillo, G.5
Calabrese, L.6
-
181
-
-
0021104498
-
Hydroperoxide anion, HO-2, is an affinity reagent for the inactivation of yeast Cu. Zn-superoxide dismutase: Modification of one histidine per subunit
-
Blech D.M., Borders C.L.J. Hydroperoxide anion, HO-2, is an affinity reagent for the inactivation of yeast Cu. Zn-superoxide dismutase: modification of one histidine per subunit. Arch. Biochem. Biophys. 224:1983;579-586.
-
(1983)
Arch. Biochem. Biophys.
, vol.224
, pp. 579-586
-
-
Blech, D.M.1
Borders, C.L.J.2
-
183
-
-
1842291518
-
Metal-catalyzed oxidation of histidine in human growth hormone
-
Zhao F., Ghezzo-Schomeich E., Aced G.I., Hong J., Milby T., Schoneich C. Metal-catalyzed oxidation of histidine in human growth hormone. J. Biol. Chem. 272:1997;9019-9029.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9019-9029
-
-
Zhao, F.1
Ghezzo-Schomeich, E.2
Aced, G.I.3
Hong, J.4
Milby, T.5
Schoneich, C.6
-
184
-
-
0000393376
-
Human amyloid-derived Aβ contains tyrosine cross-linked oligomers
-
Atwood C.S., Moir R.D., Jones W.D., Huang X., Perry G., Tanzi R.E., Roher A.E., Bush A.I. Human amyloid-derived Aβ contains tyrosine cross-linked oligomers. Neurobiol. Aging. 21:2000;S199.
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 199
-
-
Atwood, C.S.1
Moir, R.D.2
Jones, W.D.3
Huang, X.4
Perry, G.5
Tanzi, R.E.6
Roher, A.E.7
Bush, A.I.8
-
185
-
-
0033615580
-
The presenilins in Alzheimer's disease - Proteolysis holds the key
-
Haass C., De Strooper B. The presenilins in Alzheimer's disease - proteolysis holds the key. Science. 286:1999;916-919.
-
(1999)
Science
, vol.286
, pp. 916-919
-
-
Haass, C.1
De Strooper, B.2
-
186
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., Seubert P. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 400:1999;173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
187
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F., Cannon C., Barbour R., Burke R.L., Games D., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Lieberburg I., Motter R., Nguyen M., Soriano F., Vasquez N., Weiss K., Welch B., Seubert P., Schenk D., Yednock T. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6:2000;916-919.
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
188
-
-
0034663175
-
3rd Link between heart disease, cholesterol, and Alzheimer's disease: A review
-
Sparks D.L., Martin T.A., Gross D.R., Hunsaker J.C. 3rd Link between heart disease, cholesterol, and Alzheimer's disease: a review. Microsc. Res. Tech. 50:2000;287-290.
-
(2000)
Microsc. Res. Tech.
, vol.50
, pp. 287-290
-
-
Sparks, D.L.1
Martin, T.A.2
Gross, D.R.3
Hunsaker, J.C.4
-
189
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice
-
Cherny R.A., Atwood C.S., Xilinas M.E., Gray D.N., Jones W.D., McLean C.A., Barnham K.J., Volitakis I., Fraser F.W., Kim Y., Huang X., Goldstein L.E., Moir R.D., Lim J.T., Beyreuther K., Zheng H., Tanzi R.E., Masters C.L., Bush A.I. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. J30:2001;665-676.
-
(2001)
Neuron
, vol.J30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
Gray, D.N.4
Jones, W.D.5
McLean, C.A.6
Barnham, K.J.7
Volitakis, I.8
Fraser, F.W.9
Kim, Y.10
Huang, X.11
Goldstein, L.E.12
Moir, R.D.13
Lim, J.T.14
Beyreuther, K.15
Zheng, H.16
Tanzi, R.E.17
Masters, C.L.18
Bush, A.I.19
-
190
-
-
0030250567
-
Inflammation and Alzheimer's disease pathogenesis
-
Rogers J., Webster S., Lue L.F., Brachova L., Civin W.H., Emmerling M., Shivers B., Walker D., McGeer P. Inflammation and Alzheimer's disease pathogenesis. Neurobiol. Aging. 17:1996;681-686.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 681-686
-
-
Rogers, J.1
Webster, S.2
Lue, L.F.3
Brachova, L.4
Civin, W.H.5
Emmerling, M.6
Shivers, B.7
Walker, D.8
McGeer, P.9
-
191
-
-
0034638379
-
Is oxidative damage by amyloid and prion peptides mediated by hydrogen atom transfer from glycine carbon to methionine sulfur within sheets?
-
Rauk A., Armstrong D.A., Fairlie D.P. Is oxidative damage by amyloid and prion peptides mediated by hydrogen atom transfer from glycine carbon to methionine sulfur within sheets? J. Am. Chem. Soc. 122:2000;9761-9767.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 9761-9767
-
-
Rauk, A.1
Armstrong, D.A.2
Fairlie, D.P.3
|