Amyloid-β: A vascular sealant that protects against hemorrhage?

Journal of Neuroscience Research

Volumn 70, Issue 3, 2002, Pages 356-

  Atwood, Craig S ^a   Bishop, Glenda M ^a   Perry, George ^a   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; COPPER; SEALANT; ZINC;

ACIDOSIS; ANTIOXIDANT ACTIVITY; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; BRAIN PROTECTION; CHELATION; CLINICAL TRIAL; DRUG ACTIVITY; ENCEPHALITIS; HEAD INJURY; HUMAN; MENINGITIS; METAL BINDING; NONHUMAN; NOTE; PRIORITY JOURNAL; STROKE; VACCINATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; ENCEPHALITIS; ENDOTHELIUM, VASCULAR; HUMANS; INTRACRANIAL HEMORRHAGES; VACCINATION;

EID: 0037010308     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10388     Document Type: Note

References (7)

1. Atwood CS, Huang X, Moir RD, Bacarra NM, Romano D, Tanzi RE, Bush AI. 1998. Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem 273:12817-12826.
2. Atwood CS, Huang X, Moir RD, Smith MA, Tanzi RE Roher AE, Bush AI, Perry G. 2001. Neuroinflammatory responses in the Alzheimer's disease brain promote the oxidative post-translational modification of amyloid deposits. In: Iqbal K, Sisodia SS, Winblad B, editors. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics. United Kingdom: John Wiley & Sons, Ltd. p 341-361.
3. Chan C-W, Dharmarajan A, Atwood CS, Huang X, Tanzi RE, Bush AI, Martins RN. 1999. Anti-apoptotic action of Alzheimer Aβ. Alzheimer's Reports 2:1-6.
4. Perry G, Nunomura A, Raina AK, Smith MA. 2000. Amyloid-β junkies. Lancet 355:757.
5. Pluta R, Barcikowska M, Misicka A, Lipkowski AW, Spisacka S, Januszewski S. 1999. Ischemic rats as a model in the study of the neurobiological role of human β-amyloid peptide. Time-dependent disappearing diffuse amyloid plaques in brain. NeuroReport 10:3615-3619.
6. Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI. 1994. Beta amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry 57:419-425.
7. Smith MA, Joseph JA, Arson PG. 2000. Tracking the culprit in Alzheimer's disease. Ann N Y Acad Sci 924:35-38.