The influence of the carboxyl terminus of the Alzheimer Aβ peptide on its conformation, aggregation, and neurotoxic properties

NeuroMolecular Medicine

Volumn 1, Issue 1, 2002, Pages 81-94

  Soreghan, Brian ^a   Pike, Christian ^b   Kayed, Rakez ^a   Tian, Wenquiang ^a   Milton, Saskia ^a   Cotman, Carl ^a   Glabe, Charles G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aggregation; Amyloid A ; Fibril formation; Neurotoxicity

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-28]; BETA ADRENERGIC RECEPTOR; CHIMERIC PROTEIN; DODECYL SULFATE SODIUM; LOW DENSITY LIPOPROTEIN RECEPTOR; OLIGOMER; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); EPITOPE; HYBRID PROTEIN; NEUROTOXIN; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA SHEET; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; CHIMERA; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EPITOPE MAPPING; FIBER; HIPPOCAMPUS; HYDROPHOBICITY; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PEPTIDE ANALYSIS; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; SENILE PLAQUE; AMINO ACID SEQUENCE; CHEMISTRY; CIRCULAR DICHROISM; HUMAN; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PH; PROTEIN SECONDARY STRUCTURE; ULTRASTRUCTURE;

ANIMALIA;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; CIRCULAR DICHROISM; EPITOPES; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; NEUROTOXINS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS;

EID: 0036358289     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1385/NMM:1:1:81     Document Type: Article

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