Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Nature Medicine

Volumn 6, Issue 8, 2000, Pages 916-919

  Bard, Frédérique ^a   Cannon, Catherine ^a   Barbour, Robin ^a   Burke, Rae Lyn ^a   Games, Dora ^a   Grajeda, Henry ^a   Guido, Teresa ^a   Hu, Kang ^a   Huang, Jiping ^a   Johnson Wood, Kelly ^a   Khan, Karen ^a   Kholodenko, Dora ^a   Lee, Mike ^a   Lieberburg, Ivan ^a   Motter, Ruth ^a   Nguyen, Minh ^a   Soriano, Ferdie ^a   Vasquez, Nicki ^a   Weiss, Kim ^a   Welch, Brent ^a   Seubert, Peter ^a   Schenk, Dale ^a   Yednock, Ted ^a   more..

^a ELAN PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY; AMYLOID PRECURSOR PROTEIN; FC RECEPTOR; MONOCLONAL ANTIBODY; PLATELET DERIVED GROWTH FACTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN TISSUE; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SENILE PLAQUE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNIZATION; MICE; MICE, TRANSGENIC; PHAGOCYTOSIS; SENILE PLAQUES;

EID: 0033835996     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/78682     Document Type: Article

References (10)

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