A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage

Journal of Neuroscience

Volumn 22, Issue 12, 2002, Pages 4833-4841

  Zou, Kun ^a   Gong, Jian Sheng ^a   Yanagisawa, Katsuhiko ^a   Michikawa, Makoto ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Alzheimer's disease; Amyloid protein; Antioxidant; Neuronal death; Oxygen radicals; Transition metals

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; ANTIOXIDANT; CATALASE; EDETIC ACID; GLUTARALDEHYDE; IRON BINDING PROTEIN; METAL; TRANSFERRIN; AMYLOID BETA PROTEIN[1-40]; ASCORBIC ACID; CHELATING AGENT; COPPER; FERRIC ION; IRON; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; SUPEROXIDE; TACHYKININ;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; ANIMAL; CELL CULTURE; CELL DEATH; CULTURE MEDIUM; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NERVE CELL; SPRAGUE DAWLEY RAT;

AMYLOID BETA-PROTEIN; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CELL DEATH; CELLS, CULTURED; CHELATING AGENTS; COPPER; CULTURE MEDIA; FERRIC COMPOUNDS; IRON; LIPID PEROXIDATION; METALS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDES; TACHYKININS;

EID: 0037096251     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-12-04833.2002     Document Type: Article

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