Inhibition of NF-κB potentiates amyloid β-mediated neuronal apoptosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 16, 1999, Pages 9409-9414

  Kaltschmidt, Barbara ^a   Uherek, Martin ^a   Wellmann, Henning ^a   Volk, Benedikt ^a   Kaltschmidt, Christian ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

I B ; Neuroprotection; Oxidative stress; Preconditioning; Tumor necrosis factor

Indexed keywords

AMYLOID BETA PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; AMYLOID BETA PROTEIN[1-40]; DNA BINDING PROTEIN; I KAPPA B; NEUROPROTECTIVE AGENT; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; GRANULE CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MOLECULAR DYNAMICS; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENILE PLAQUE; ANIMAL; CELL CULTURE; CEREBELLUM; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALIA;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBELLUM; DNA-BINDING PROTEINS; HUMANS; I-KAPPA B PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PEPTIDE FRAGMENTS; RATS; RECOMBINANT PROTEINS; SENILE PLAQUES; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033529417     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.16.9409     Document Type: Article

References (62)

1. Selkoe, D. J. (1994) Annu. Rev. Neurosci. 17, 489-517.
2. Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L. & Beyreuther, K. (1985) Proc. Natl. Acad. Sci. USA 82, 4245-4249.
3. Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K. & Muller, H. B. (1987) Nature (London) 325, 733-736.
4. Braak, H. & Braak, E. (1997) Neurobiol. Aging 18, 351-357.
5. Li, J. J., Dickson, D., Hof, P. R. & Vlassara, H. (1998) Mol. Med. 4, 46-60.
6. Yan, S. D., Van, S. F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M. A., Perry, G., Godman, G. C., Nawroth, P., et al. (1995) Nat. Med. 1, 693-699.
7. Haass, C. (1997) Neuron 18, 687-690.
8. Borchelt, D. R., Ratovitski, T., van Lare, J., Lee, M. K., Gonzales, V., Jenkins, N. A., Copeland, N. G., Price, D. L. & Sisodia, S. S. (1997) Neuron 19, 939-945.
9. Weidemann, A., Paliga, K., Durrwang, U., Czech, C., Evin, G., Masters, C. L. & Beyreuther, K. (1997) Nat. Med. 3, 328-332.
10. Guo, Q., Robinson, N. & Mattson, M. P. (1998) J. Biol. Chem. 273, 12341-12351.
11. Müller, U., Cristina, N., Li, Z. W., Wolfer, D. P., Lipp, H. P., Rulicke, T., Brandner, S., Aguzzi, A. & Weissmann, C. (1994) Cell 79, 755-765.
12. Zheng, H., Jiang, M., Trumbauer, M. E., Sirinathsinghji, D. J., Hopkins, R., Smith, D. W., Heavens, R. P., Dawson, G. R., Boyce, S., Conner, M. W., et al. (1995) Cell 81, 525-531.
13. Yankner, B. A., Duffy, L. K. & Kirschner, D. A. (1990) Science 250, 279-282.
14. Kaltschmidt, B., Uherek, M., Volk, B., Baeuerle, P. A. & Kaltschmidt, C. (1997) Proc. Natl. Acad. Sci. USA 94, 2642-2647.
15. Behl, C., Davis, J. B., Lesley, R. & Schubert, D. (1994) Cell 77, 817-827.
16. Lezoualc'h, F., Sagara, Y., Holsboer, F. & Behl, C. (1998) J. Neurosci. 18, 3224-3232.
17. Baldwin, A. J. (1996) Annu. Rev. Immunol. 14, 649-683.
18. Whiteside, S. T. & Israël, A. (1997) Semin. Cancer Biol. 8, 75-82.
19. Whiteside, S. T., Epinat, J. C., Rice, N. R. & Israel, A. (1997) EMBO J. 16, 1413-1426.
20. O'Neill, L. A. J. & Kaltschmidt, C. (1997) Trends Neurosci. 20, 252-258.
21. Guerrini, L., Blasi, F. & Denis, D. S. (1995) Proc. Natl. Acad. Sci. USA 92, 9077-9081.
22. Kaltschmidt, C., Kaltschmidt, B. & Baeuerle, P. A. (1995) Proc. Natl. Acad. Sci. USA 92, 9618-9622.
23. Wood, J. N. (1995) Neurosci. Lett. 192, 41-44.
24. Kaltschmidt, C., Kaltschmidt, B., Neumann, H., Wekerle, H. & Baeuerle, P. A. (1994) Mol. Cell. Biol. 14, 3981-3992.
25. Schmidt-Ullrich, R., Memet, S., Lilienbaum, A., Feuillard, J., Raphael, M. & Israel, A. (1996) Development (Cambridge, U.K.) 122, 2117-2128.
26. Carter, B. D., Kaltschmidt, C., Kaltschmidt, B., Offenhauser, N., Böhm-Matthaei, R., Baeuerle, P. A. & Barde, Y. A. (1996) Science 272, 542-545.
27. Stancovski, I. & Baltimore, D. (1997) Cell 91, 299-302.
28. Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H. E., Kay, R. J. & Israël, A. (1998) Cell 93, 1231-1240.
29. Rothwarf, D. M., Zandi, E., Natoli, G. & Karin, M. (1998) Nature (London) 395, 297-300.
30. Cohen, L., Henzel, W. J. & Baeuerle, P. A. (1998) Nature (London) 395, 292-296.
31. Kaltschmidt, C., Kaltschmidt, B., Henkel, T., Stockinger, H. & Baeuerle, P. A. (1995) Biol. Chem. Hoppe Seyler 376, 9-16.
32. Liu, Z. G., Hsu, H., Goeddel, D. V. & Karin, M. (1996) Cell 87, 565-576.
33. Dickson, D. W. (1997) J. Neuropathol. Exp. Neurol. 56, 321-339.
34. Bethea, J. R., Castro, M., Keane, R. W., Lee, T. T., Dietrich, W. D. & Yezierski, R. P. (1998) J. Neurosci. 18, 3251-3260.
35. Tao, X., Finkbeiner, S., Arnold, D. B., Shaywitz, A. J. & Greenberg, M. E. (1998) Neuron 20, 709-726.
36. Deisseroth, K., Heist, E. K. & Tsien, R. W. (1998) Nature (London) 392, 198-202.
37. Cheng, B., Christakos, S. & Mattson, M. P. (1994) Neuron 12, 139-153.
38. Barger, S. W. & Mattson, M. P. (1996) Mol. Brain Res. 40, 116-126.
39. Mattson, M. P., Goodman, Y., Luo, H., Fu, W. & Furukawa, K. (1997) J. Neurosci. Res. 49, 681-697.
40. Traenckner, E. B., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S. & Baeuerle, P. A. (1995) EMBO J. 14, 2876-2883.
41. Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z. & Rothe, M. (1997) Cell 90, 373-383.
42. Huell, M., Strauss, S., Volk, B., Berger, M. & Bauer, J. (1995) Acta Neuropathol. 89, 544-551.
43. Terai, K., Matsuo, A., McGeer, E. G. & McGeer, P. L. (1996) Brain. Res. 739, 343-349.
44. Kitamura, Y., Shimohama, S., Ota, T., Matsuoka, Y., Nomura, Y. & Taniguchi, T. (1997) Neurosci. Lett. 237, 17-20.
45. Boissiere, F., Hunot, S., Faucheux, B., Duyckaerts, C., Hauw, J. J., Agid, Y. & Hirsch, E. C. (1997) NeuroReport 8, 2849-2852.
46. Schreck, R., Rieber, P. & Baeuerle, P. A. (1991) EMBO J. 10, 2247-2258.
47. Kaltschmidt, B., Sparna, T. & Kaltschmidt, C. (1999) Antioxidants Redox Signaling, in press.
48. Salminen, A., Liu, P. K. & Hsu, C. Y. (1995) Biochem. Biophys. Res. Commun. 212, 939-944.
49. Baltimore, D. (1988) Nature (London) 335, 395-396.
50. Dickson, D. W. (1997) Neurobiol. Aging 18, 21-26.
51. Lassmann, H., Bancher, C., Breitschopf, H., Wegiel, J., Bobinski, M., Jellinger, K. & Wisniewski, H. M. (1995) Acta Neuropathol. 89, 35-41.
52. Sheng, J. G., Zhou, X. Q., Mrak, R. E. & Griffin, W. S. (1998) J. Neuropathol. Exp. Neurol. 57, 714-717.
53. Van Antwerp, D. J., Martin, S. J., Verma, I. M. & Green, D. R. (1998) Trends Cell Biol. 8, 107-111.
54. McGeer, P. L., Itagaki, S., Tago, H. & McGeer, E. G. (1987) Neurosci. Lett. 79, 195-200.
55. Dickson, D. W., Farlo, J., Davies, P., Crystal, H., Fuld, P. & Yen, S. H. (1988) Am. J. Pathol. 132, 86-101.
56. Wisniewski, H. M., Wegiel, J., Wang, K. C., Kujawa, M. & Lach, B. (1989) Can. J. Neurol. Sci. 16, 535-542.
57. Mattiace, L. A., Davies, P. & Dickson, D. W. (1990) Am. J. Pathol. 136, 1101-1114.
58. Mattiace, L. A., Davies, P., Yen, S. H. & Dickson, D. W. (1990) Acta Neuropathol. 80, 493-498.
59. Dickson, D. W., Lee, S. C., Mattiace, L. A., Yen, S. H. & Brosnan, C. (1993) Glia 7, 75-83.
60. Meda, L., Cassatella, M. A., Szendrei, G. I., Otvos, L., Jr., Baron, P., Villalba, M., Ferrari, D. & Rossi, F. (1995) Nature (London) 374, 647-650.
61. Togashi, H., Sasaki, M., Frohman, E., Taira, E., Ratan, R. R., Dawson, T. M. & Dawson, V. L. (1997) Proc. Natl. Acad. Sci. USA 94, 2676-2680.
62. Wellmann, H., Kaltschmidt, B. & Kaltschmidt, C. (1999) J. Neurosci. Methods, in press.