Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin

Free Radical Biology and Medicine

Volumn 26, Issue 11-12, 1999, Pages 1508-1512

  Castellani, Rudy J ^a   Smith, Mark A ^b   Nunomura, Akihiko ^b,c   Harris, Peggy L R ^b   Perry, George ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Alzheimer disease; Amyloid ; Ceruloplasmin; Copper; Free radicals; Iron; Neurofibrillary tangles; Oxidative stress; Senile plaques

Indexed keywords

AMYLOID BETA PROTEIN; CERULOPLASMIN; COPPER; FREE RADICAL; IRON; REACTIVE OXYGEN METABOLITE;

AGED; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOREACTIVITY; NEUROFIBRILLARY TANGLE; NEUROPIL; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; REGULATORY MECHANISM; SENILE PLAQUE;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CASE-CONTROL STUDIES; CERULOPLASMIN; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IRON; MIDDLE AGED; NEUROFIBRILLARY TANGLES; NEUROPIL; OXIDATION-REDUCTION;

EID: 0033006576     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00016-7     Document Type: Article

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