Aβ(25-35) peptide displays H2O2-like reactivity towards aqueous FE2+, nitroxide spin probes, Ant) synaptosomal membrane proteins

Life Sciences

Volumn 58, Issue 3, 1995, Pages 217-228

  Butterfield, D Allan ^a   Martin, Laura ^a   Carney, John M ^a   Hensley, Kenneth ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

amyloid; free radicals; nitroxides; protein oxidation; spin labels

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN [25-35]; FREE RADICAL; IRON; MEMBRANE PROTEIN; NITROXIDE; PEPTIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; GERBIL; MEMBRANE DAMAGE; NEOCORTEX; NEUROTOXICITY; NONHUMAN; SPIN LABELING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FERROUS COMPOUNDS; FREE RADICALS; GERBILLINAE; HYDROGEN PEROXIDE; MEMBRANE PROTEINS; PEPTIDE FRAGMENTS; SPIN LABELS; SYNAPTOSOMES;

ANIMALIA; GERBILLINAE;

EID: 0030050065     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(95)02279-1     Document Type: Article

References (24)

1. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
2. Spin Labeling of Membrane Proteins in Mammalian Brain Synaptic Plasma Membranes: Partial Characterization