Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc

Journal of Biological Chemistry

Volumn 275, Issue 26, 2000, Pages 19439-19442

  Cuajungco, Math P ^a,b   Goldstein, Lee E ^a   Nunomura, Akihiko ^c,d   Smith, Mark A ^c   Lim, James T ^a   Atwood, Craig S ^a,c   Huang, Xudong ^a   Farrag, Yasser W ^a   Perry, George ^c   Bush, Ashley I ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ZINC ION;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GENE SILENCING; HUMAN; HUMAN CELL; NEOCORTEX; NEUROTOXICITY; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CELL LINE; CELL SURVIVAL; CELL-FREE SYSTEM; CELLS, CULTURED; COPPER; GUANOSINE; HUMANS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; IONS; MIDDLE AGED; NEURONS; OXIDATION-REDUCTION; OXYGEN; RATS; ZINC;

EID: 0034733705     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C000165200     Document Type: Article

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