Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis

Journal of Neuroscience

Volumn 18, Issue 23, 1998, Pages 9790-9799

  Bursztajn, Sherry ^a,e   DeSouza, Richard ^b   McPhie, Donna L ^c   Berman, S A ^a,e   Shioi, Junichi ^d   Robakis, Nikolaos K ^d   Neve, Rachael L ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MCLEAN HOSPITAL   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Apoptosis; DNA fragmentation; Neurodegeneration; Presenilin

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DNA FRAGMENT; ETOPOSIDE; PRESENILIN 1; STAUROSPORINE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CELL TYPE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0032400818     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-23-09790.1998     Document Type: Article

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