-
1
-
-
0032952809
-
Stroke incidence and survival among middle-aged adults
-
ROSAMOND WD, FOLSOM AR, CHAMBLESS LI et al.: Stroke incidence and survival among middle-aged adults. Stroke (1999) 30:736-743.
-
(1999)
Stroke
, vol.30
, pp. 736-743
-
-
Rosamond, W.D.1
Folsom, A.R.2
Chambless, L.I.3
-
2
-
-
0030983708
-
Mortality by cause for eight regions of the world: Global burden of disease study
-
MURRAY CJL, LOPEZ AD: Mortality by cause for eight regions of the world: global burden of disease study. Lancet (1997) 349:1269-1276.
-
(1997)
Lancet
, vol.349
, pp. 1269-1276
-
-
Murray, C.J.L.1
Lopez, A.D.2
-
3
-
-
0032735073
-
The incidence and occurrence of total (first-ever and recurrent) stroke
-
WILLIAMS GR, JIANG JG, MATCHAR DB, SAMSA GP: The incidence and occurrence of total (first-ever and recurrent) stroke. Stroke (2000) 31:2523-2528.
-
(2000)
Stroke
, vol.31
, pp. 2523-2528
-
-
Williams, G.R.1
Jiang, J.G.2
Matchar, D.B.3
Samsa, G.P.4
-
4
-
-
0033598606
-
Treatment and secondary prevention of stroke: Evidence, costs, and effects on individuals and populations
-
HANKEY GJ, WARLOW CP: Treatment and secondary prevention of stroke: evidence, costs, and effects on individuals and populations. Lancet (1999) 354:1457-1463.
-
(1999)
Lancet
, vol.354
, pp. 1457-1463
-
-
Hankey, G.J.1
Warlow, C.P.2
-
5
-
-
0029794598
-
Lifetime cost of stroke in the United States
-
TAYLOR TN, DAVIS PH, TORNER JC, HOLMES J, MEYER JW, JACOBSON MF: Lifetime cost of stroke in the United States. Stroke (1996) 27:1459-1466.
-
(1996)
Stroke
, vol.27
, pp. 1459-1466
-
-
Taylor, T.N.1
Davis, P.H.2
Torner, J.C.3
Holmes, J.4
Meyer, J.W.5
Jacobson, M.F.6
-
6
-
-
0032744573
-
Thrombolysis in acute ischemic stroke: Controlled trials and clinical experience
-
HACKE W, BROTT T, CAPLAN LR et al.: Thrombolysis in acute ischemic stroke: controlled trials and clinical experience. Neurology (1999) 53(Suppl.):S3-S14.
-
(1999)
Neurology
, vol.53
, Issue.SUPPL.
-
-
Hacke, W.1
Brott, T.2
Caplan, L.R.3
-
7
-
-
0034983276
-
Trends in acute ischemic stroke trials through the 20th century
-
KIDWELL CS, LIEBESKIND DS, STARKMAN S, SAVER JL: Trends in acute ischemic stroke trials through the 20th century. Stroke (2001) 32:1349-1359.
-
(2001)
Stroke
, vol.32
, pp. 1349-1359
-
-
Kidwell, C.S.1
Liebeskind, D.S.2
Starkman, S.3
Saver, J.L.4
-
8
-
-
0034855790
-
Thrombolytic therapy for ischemic stroke - A review. Part I - Intravenous thrombolysis
-
SCHELLINGER PD, FIEBACH JB, MOHR A, RINGLEB MD, JANSEN O, HACKE W: Thrombolytic therapy for ischemic stroke - a review. Part I - intravenous thrombolysis. Crit. Care Med. (2001) 29:1812-1818. Comprehensive review of clinical trials of intravenous thrombolytic therapy for acute stroke.
-
(2001)
Crit. Care Med.
, vol.29
, pp. 1812-1818
-
-
Schellinger, P.D.1
Fiebach, J.B.2
Mohr, A.3
Ringleb, M.D.4
Jansen, O.5
Hacke, W.6
-
9
-
-
0033485522
-
Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS study: A randomized controlled trial. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke
-
CLARK WM, WISSMAN S, ALBERS GW, JHAMANDAS JH, MADDEN KP, HAMILTON S: Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS study: a randomized controlled trial. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke. JAMA (1999) 282:2019-2126.
-
(1999)
JAMA
, vol.282
, pp. 2019-2126
-
-
Clark, W.M.1
Wissman, S.2
Albers, G.W.3
Jhamandas, J.H.4
Madden, K.P.5
Hamilton, S.6
-
10
-
-
0037163461
-
Thrombolysis for acute stroke in routine clinical practice
-
BRAVATA DM, KIM N, CONCATO J et al.: Thrombolysis for acute stroke in routine clinical practice. Arch. Int. Med. (2002) 162:1994-2001.
-
(2002)
Arch. Int. Med.
, vol.162
, pp. 1994-2001
-
-
Bravata, D.M.1
Kim, N.2
Concato, J.3
-
11
-
-
0030985284
-
CAST: Randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke
-
CHEN ZM, COLLINS R, LIU LS, PAN HC, PETO R: CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. Lancet (1997) 349:1641-1649.
-
(1997)
Lancet
, vol.349
, pp. 1641-1649
-
-
Chen, Z.M.1
Collins, R.2
Liu, L.S.3
Pan, H.C.4
Peto, R.5
-
12
-
-
0031787520
-
Antithrombotic and thrombolytic therapy for ischemic stroke
-
ALBERS GW, EASTON JD, SACCO RL, TEAL P: Antithrombotic and thrombolytic therapy for ischemic stroke. Chest (1998) 114:S683-S698. Comprehensive review of clinical trials of antithrombotic and thrombolytic therapies for stroke.
-
(1998)
Chest
, vol.114
-
-
Albers, G.W.1
Easton, J.D.2
Sacco, R.L.3
Teal, P.4
-
13
-
-
0030911057
-
The international stroke trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke
-
SANDERCOCK P, COLLINS R, COUNSELL C et al.: The international stroke trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. Lancet (1997) 349:1569-1581. Clinical trial which demonstrates that aspirin, but not heparin, has some efficacy for treatment of acute stroke.
-
(1997)
Lancet
, vol.349
, pp. 1569-1581
-
-
Sandercock, P.1
Collins, R.2
Counsell, C.3
-
14
-
-
0033933547
-
Low molecular-weight heparins and heparinoids in acute ischemic stroke
-
BATH PMW, IDDENDEN R, BATH FJ: Low molecular-weight heparins and heparinoids in acute ischemic stroke. Stroke (2000) 31:1770-1778. Meta-analysis of clinical trials which demonstrates lack of efficacy of low molecular-weight heparins for acute stroke.
-
(2000)
Stroke
, vol.31
, pp. 1770-1778
-
-
Bath, P.M.W.1
Iddenden, R.2
Bath, F.J.3
-
16
-
-
0034884152
-
Open-label dose-titration safety and efficacy study of tizanidine hydrochloride in the treatment of spasticity associated with chronic stroke
-
GELBER DA, GOOD DC, DROMERICK A, SERGAY S, RICHARDSON M: Open-label dose-titration safety and efficacy study of tizanidine hydrochloride in the treatment of spasticity associated with chronic stroke. Stroke (2001) 32:1841-1846.
-
(2001)
Stroke
, vol.32
, pp. 1841-1846
-
-
Gelber, D.A.1
Good, D.C.2
Dromerick, A.3
Sergay, S.4
Richardson, M.5
-
17
-
-
0037043682
-
Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after a stroke
-
BRASHEAR A, GORDON MF, ELOVIC E et al.: Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after a stroke. N. Engl. J. Med. (2002) 347:395-400.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 395-400
-
-
Brashear, A.1
Gordon, M.F.2
Elovic, E.3
-
18
-
-
0036327146
-
Vascular dementia revisited: Diagnosis, pathogenesis, treatment and prevention
-
ROMAN GC: Vascular dementia revisited: diagnosis, pathogenesis, treatment and prevention. Med. Clin. North Am. (2002) 86:477-499. Comprehensive review of emerging treatments of vascular dementia.
-
(2002)
Med. Clin. North Am.
, vol.86
, pp. 477-499
-
-
Roman, G.C.1
-
20
-
-
0027364283
-
Effect of CDP-choline on cognition and immune function in Alzheimer's disease and multi-infarct dementia
-
CACEBELOS R, ALVAREZ XA, FRANCO-MASIDE A et al.: Effect of CDP-choline on cognition and immune function in Alzheimer's disease and multi-infarct dementia. Ann. NY Acad. Sci. (1993) 695:321-323.
-
(1993)
Ann. NY Acad. Sci.
, vol.695
, pp. 321-323
-
-
Cacebelos, R.1
Alvarez, X.A.2
Franco-Maside, A.3
-
21
-
-
0033202701
-
Pharmacologic rationale for memantine in chronic cerebral hypoperfusion, especially vascular dementia
-
MOBIUS HJ, STOFFLER A: Pharmacologic rationale for memantine in chronic cerebral hypoperfusion, especially vascular dementia. Alzheimer Dis. Assoc. Disord. (1999) 13(Suppl. 3):S172-S178.
-
(1999)
Alzheimer Dis. Assoc. Disord.
, vol.13
, Issue.SUPPL. 3
-
-
Mobius, H.J.1
Stoffler, A.2
-
22
-
-
0030846507
-
Stroke prevention - Windows of opportunity and failed expectations - A discussion of modifiable cardiovascular risk factors and a prevention proposal
-
GORELICK PB: Stroke prevention - windows of opportunity and failed expectations - a discussion of modifiable cardiovascular risk factors and a prevention proposal. Neuroepidemiol. (1997) 16:163-173.
-
(1997)
Neuroepidemiol.
, vol.16
, pp. 163-173
-
-
Gorelick, P.B.1
-
23
-
-
0037160928
-
Use of ramipril in preventing stroke: Double blind randomised trial
-
BOSCH J, YUSUF S, POGUE J et al.: Use of ramipril in preventing stroke: double blind randomised trial. Br. Med. Bull. (2002) 324:699-703.
-
(2002)
Br. Med. Bull.
, vol.324
, pp. 699-703
-
-
Bosch, J.1
Yusuf, S.2
Pogue, J.3
-
24
-
-
0038367784
-
New horizons for stroke prevention: PROGRESS and HOPE
-
GORELICK PB: New horizons for stroke prevention: PROGRESS and HOPE. Lancet Neurol. (2002) 1:149-156.
-
(2002)
Lancet Neurol.
, vol.1
, pp. 149-156
-
-
Gorelick, P.B.1
-
25
-
-
0035124747
-
Primary stroke prevention
-
DE FREITAS GR, BOGOUSSLAVSKY J: Primary stroke prevention. Eur. J. Neurol. (2001) 8:1-15. Reviews stroke risk factors and stroke prevention clinical trials.
-
(2001)
Eur. J. Neurol.
, vol.8
, pp. 1-15
-
-
De Freitas, G.R.1
Bogousslavsky, J.2
-
26
-
-
0028120906
-
Collaborative overview of randomised trials of antiplatelet therapy. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
-
COLLINS R, PETO R, BAIGENT C et al.: Collaborative overview of randomised trials of antiplatelet therapy. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br. Med. J. (1994) 308:81-106.
-
(1994)
Br. Med. J.
, vol.308
, pp. 81-106
-
-
Collins, R.1
Peto, R.2
Baigent, C.3
-
27
-
-
0032557171
-
Rising stroke rates spur efforts to indentify risks, prevent disease
-
STEPHENSON J: Rising stroke rates spur efforts to indentify risks, prevent disease. JAMA (1998) 279:1239-1240.
-
(1998)
JAMA
, vol.279
, pp. 1239-1240
-
-
Stephenson, J.1
-
28
-
-
0033199996
-
Pathobiology of ischaemic stroke: An integrated view
-
DIRNAGL U, IADECOLA C, MOSKOWITZ MA: Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. (1999) 22:391-397. Good overview of the ischaemic cascade.
-
(1999)
Trends Neurosci.
, vol.22
, pp. 391-397
-
-
Dirnagl, U.1
Iadecola, C.2
Moskowitz, M.A.3
-
29
-
-
0036326170
-
Inflammatory cell adhesion molecules in ischemic cerebrovascular disease
-
FRIJNS CJM, KAPPELLE LJ: Inflammatory cell adhesion molecules in ischemic cerebrovascular disease. Stroke (2002) 33:2115-2122. Review of the role of cell adhesion molecules in cerebral ischaemia.
-
(2002)
Stroke
, vol.33
, pp. 2115-2122
-
-
Frijns, C.J.M.1
Kappelle, L.J.2
-
30
-
-
0031718663
-
Inflammation and glial responses in ischemic brain lesions
-
STOLL G, JANDER S, SCHROETER M: Inflammation and glial responses in ischemic brain lesions. Prog. Neurobiol. (1998) 56:149-171. Review of the inflammatory response following focal cerebral ischaemia.
-
(1998)
Prog. Neurobiol.
, vol.56
, pp. 149-171
-
-
Stoll, G.1
Jander, S.2
Schroeter, M.3
-
32
-
-
0021683344
-
The profile of recovery from stroke and factors influencing outcome
-
KOTILA M, WALTIMO O, NIEMI ML, LAAKSONEN R, LEMPINEN M: The profile of recovery from stroke and factors influencing outcome. Stroke (1984) 15:1039-1044.
-
(1984)
Stroke
, vol.15
, pp. 1039-1044
-
-
Kotila, M.1
Waltimo, O.2
Niemi, M.L.3
Laaksonen, R.4
Lempinen, M.5
-
33
-
-
0028808693
-
Neocortical neural sprouting, synaptogenesis and behavioural recovery after neocortical infarction in rats
-
STROEMER RP, KENT TA, HULSEBOSCH CE: Neocortical neural sprouting, synaptogenesis and behavioural recovery after neocortical infarction in rats. Stroke (1995) 26:2135-2144.
-
(1995)
Stroke
, vol.26
, pp. 2135-2144
-
-
Stroemer, R.P.1
Kent, T.A.2
Hulsebosch, C.E.3
-
34
-
-
0030760175
-
Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction
-
KAWAMATA T, DIETRICH WD, SCHALLERT T et al.: Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc. Natl. Acad. Sci. (1997) 94:8179-8184.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 8179-8184
-
-
Kawamata, T.1
Dietrich, W.D.2
Schallert, T.3
-
35
-
-
0036196245
-
Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat
-
PAPADOPOULOS CM, TSAI S-Y, ALSBIEI T et al.: Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann. Neurol. (2002) 51:433-441. Demonstration of promotion of plasticity and functional recovery in a rat model of stroke following blockade of a myelin-associated inhibitory protein.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 433-441
-
-
Papadopoulos, C.M.1
Tsai, S.-Y.2
Alsbiei, T.3
-
36
-
-
0034725801
-
Third-generation thrombolytic drugs
-
VERSTRAETE M: Third-generation thrombolytic drugs. Am. J. Med. (2000) 109:52-58. Review of emerging thrombolytic agents.
-
(2000)
Am. J. Med.
, vol.109
, pp. 52-58
-
-
Verstraete, M.1
-
37
-
-
0038367786
-
Pro-urokinase: A study of its stability in plasma and of a mechanism for its selective fibrinolytic effect
-
PANNELL R, GUREWICH V: Pro-urokinase: a study of its stability in plasma and of a mechanism for its selective fibrinolytic effect. Blood (1986) 44:217-228.
-
(1986)
Blood
, vol.44
, pp. 217-228
-
-
Pannell, R.1
Gurewich, V.2
-
38
-
-
0034840614
-
Thrombolytic therapy for ischemic stroke - A review. Part II - Intra-arterial thromolysis, vertebrobasilar stroke, Phase IV trials, and stroke imaging
-
SCHELLINGER PD, FIEBACH JB, MOHR A, RINGLEB PA, JANSEN O, HACKE W: Thrombolytic therapy for ischemic stroke - a review. Part II - intra-arterial thromolysis, vertebrobasilar stroke, Phase IV trials, and stroke imaging. Crit. Care Med. (2001) 29:1819-1825. Comprehensive review of clinical trials of intra-arterial thrombolysis.
-
(2001)
Crit. Care Med.
, vol.29
, pp. 1819-1825
-
-
Schellinger, P.D.1
Fiebach, J.B.2
Mohr, A.3
Ringleb, P.A.4
Jansen, O.5
Hacke, W.6
-
40
-
-
0036158760
-
Inhibition of Factor IX(a) is protective in a rat model of thromboembolic stroke
-
TOOMEY JR, VALOCIK RE, KOSTER PF et al.: Inhibition of Factor IX(a) is protective in a rat model of thromboembolic stroke. Stroke (2002) 33:578-585.
-
(2002)
Stroke
, vol.33
, pp. 578-585
-
-
Toomey, J.R.1
Valocik, R.E.2
Koster, P.F.3
-
43
-
-
0036054502
-
Local intraarterial urokinase thrombolysis of acute schemic stroke with or without intravenous abciximab: A pilot study
-
LEE DH, JO KD, KIM HG et al.: Local intraarterial urokinase thrombolysis of acute schemic stroke with or without intravenous abciximab: a pilot study. J. Vasc. Intervent. Radiol. (2002) 13:769-773.
-
(2002)
J. Vasc. Intervent. Radiol.
, vol.13
, pp. 769-773
-
-
Lee, D.H.1
Jo, K.D.2
Kim, H.G.3
-
44
-
-
0033652990
-
Abnormalities of endothelial function in the pathogenesis of stroke: The importance of endothelin
-
VOLPE M, COSENTINO F: Abnormalities of endothelial function in the pathogenesis of stroke: the importance of endothelin. J. Cardiovasc. Pharmacol. (2000) 35(Suppl. 2):S45-S48.
-
(2000)
J. Cardiovasc. Pharmacol.
, vol.35
, Issue.SUPPL. 2
-
-
Volpe, M.1
Cosentino, F.2
-
45
-
-
0029745602
-
Endothelin receptor antagonist increases cerebral perfusion and reduces ischaemic damage in feline focal cerebral ischaemia
-
PATEL TR, GALBRAITH S, GRAHAM DI et al.: Endothelin receptor antagonist increases cerebral perfusion and reduces ischaemic damage in feline focal cerebral ischaemia. J. Cereb. Blood Flow Metab. (1996) 16:950-958.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 950-958
-
-
Patel, T.R.1
Galbraith, S.2
Graham, D.I.3
-
46
-
-
0032721538
-
Endothelin receptor antagonist preserves microvascular perfusion and reduced ischaemic brain damage following permanent focal ischaemia
-
DAWSON DA, SUGANO H, MCCARRON RM, HALLENBECK JM, SPATZ M: Endothelin receptor antagonist preserves microvascular perfusion and reduced ischaemic brain damage following permanent focal ischaemia. Neurochem. Res. (1999) 24:1499-1505.
-
(1999)
Neurochem. Res.
, vol.24
, pp. 1499-1505
-
-
Dawson, D.A.1
Sugano, H.2
Mccarron, R.M.3
Hallenbeck, J.M.4
Spatz, M.5
-
47
-
-
0034831353
-
Protective effect of endothelin type A receptor antagonist on brain oedema and injury after transient middle cerebral artery occlusion in rats
-
MATSUO Y, MIHARA S-I, MITSUYOSHI N, FUJIMOTO M: Protective effect of endothelin type A receptor antagonist on brain oedema and injury after transient middle cerebral artery occlusion in rats. Stroke (2001) 32:2143-2148.
-
(2001)
Stroke
, vol.32
, pp. 2143-2148
-
-
Matsuo, Y.1
Mihara, S.-I.2
Mitsuyoshi, N.3
Fujimoto, M.4
-
48
-
-
0033734717
-
Selective antagonism of endothelin-A receptors improves outcome in both head trauma and focal stroke in rat
-
BARONE FC, OHLSTEIN EH, HUNTER AJ et al.: Selective antagonism of endothelin-A receptors improves outcome in both head trauma and focal stroke in rat. J. Cardiovasc. Pharmacol. (2000) 36(Suppl. 1):S357-S361.
-
(2000)
J. Cardiovasc. Pharmacol.
, vol.36
, Issue.SUPPL. 1
-
-
Barone, F.C.1
Ohlstein, E.H.2
Hunter, A.J.3
-
49
-
-
0344065373
-
Recommendations for standards regarding predinical neuroprotective and restorative drug development
-
FINKLESTEIN SP, FISHER M, FURLAN AJ et al.: Recommendations for standards regarding predinical neuroprotective and restorative drug development. Stroke (1999) 30:2752-2758. Reviews preclinical reasons for failed stroke trials and makes recommendations for optimal preclinical development of stroke drugs.
-
(1999)
Stroke
, vol.30
, pp. 2752-2758
-
-
Finklestein, S.P.1
Fisher, M.2
Furlan, A.J.3
-
50
-
-
0034943173
-
Recommendations for clinical trial evaluation of acute stroke therapies
-
ALBERS GW, BOGOUSSLAVSKY J, BOZIK MA et al.: Recommendations for clinical trial evaluation of acute stroke therapies. Stroke (2001) 32:1598-1606. Reviews clinical reasons for failed stroke trials and makes recommendations for optimal clinical development of stroke drugs.
-
(2001)
Stroke
, vol.32
, pp. 1598-1606
-
-
Albers, G.W.1
Bogousslavsky, J.2
Bozik, M.A.3
-
51
-
-
0141676771
-
Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
-
IKONOMIDOU C, TURSKI L: Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurol. (2002) 1:383-386. Hypothesis for failure of NMDA antagonists in clinical trials.
-
(2002)
Lancet Neurol.
, vol.1
, pp. 383-386
-
-
Ikonomidou, C.1
Turski, L.2
-
52
-
-
0028952814
-
Spontaneous middle cerebral artery reperfusion in ischemic stroke: A follow-up study with transcranial doppler
-
ZANETTE EM, ROBERTI C, MANCINI G, POZZILLI C, BRAGONI M, TONI D: Spontaneous middle cerebral artery reperfusion in ischemic stroke: a follow-up study with transcranial doppler. Stroke (1995) 26:430-433.
-
(1995)
Stroke
, vol.26
, pp. 430-433
-
-
Zanette, E.M.1
Roberti, C.2
Mancini, G.3
Pozzilli, C.4
Bragoni, M.5
Toni, D.6
-
53
-
-
0032892343
-
Memantine is a clinically well tolerated N-metyld-D-aspartate (NMDA) receptor antagonist - A review of preclinical data
-
PARSONS CG, DANYSZ W, QUACK G: Memantine is a clinically well tolerated N-metyld-D-aspartate (NMDA) receptor antagonist - a review of preclinical data. Neuropharmacol. (1999) 38:735-767.
-
(1999)
Neuropharmacol.
, vol.38
, pp. 735-767
-
-
Parsons, C.G.1
Danysz, W.2
Quack, G.3
-
54
-
-
15444343987
-
YM872, a novel selective α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, reduced brain damage after permanent focal cerebral ischemia in cats
-
TAKAHASHI M, NI JW, KAWASAKI-YATSUGI S et al.: YM872, a novel selective α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, reduced brain damage after permanent focal cerebral ischemia in cats. J. Pharm. Exp. Therap. (1998) 284:467-473.
-
(1998)
J. Pharm. Exp. Therap.
, vol.284
, pp. 467-473
-
-
Takahashi, M.1
Ni, J.W.2
Kawasaki-Yatsugi, S.3
-
55
-
-
0031667548
-
YM872, a highly water-soluble AMPA antagonist, preserved the hemodynamic penumbra and reduces brain injury after permanent focal ischemia in rats
-
SHIMIZU-SASAMATA M, KANO T, ROGOWSKA J, WOLF G, MOSKOWITZ MA, LO EH: YM872, a highly water-soluble AMPA antagonist, preserved the hemodynamic penumbra and reduces brain injury after permanent focal ischemia in rats. Stroke (1998) 29:2141-2148.
-
(1998)
Stroke
, vol.29
, pp. 2141-2148
-
-
Shimizu-Sasamata, M.1
Kano, T.2
Rogowska, J.3
Wolf, G.4
Moskowitz, M.A.5
Lo, E.H.6
-
56
-
-
0033022769
-
SPD 502: A water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity
-
NIELSEN EO, VARMING T, MATHIESEN C et al.: SPD 502: a water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity. J. Pharmacol. Exp. Therap. (1999) 289:1492-1501.
-
(1999)
J. Pharmacol. Exp. Therap.
, vol.289
, pp. 1492-1501
-
-
Nielsen, E.O.1
Varming, T.2
Mathiesen, C.3
-
57
-
-
0038706172
-
Clinical experience with YM872, a novel AMPA receptor antagonist for acute ischemic stroke
-
NAPOLIELLO MJ, DE VOSS RW: Clinical experience with YM872, a novel AMPA receptor antagonist for acute ischemic stroke. Stroke (1999) 30:264.
-
(1999)
Stroke
, vol.30
, pp. 264
-
-
Napoliello, M.J.1
De Voss, R.W.2
-
58
-
-
0031771639
-
AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans
-
SANG CN, HOSTETTER MP, GRACELY RH et al.: AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans. Anesthesiology (1998) 89:1060-1067.
-
(1998)
Anesthesiology
, vol.89
, pp. 1060-1067
-
-
Sang, C.N.1
Hostetter, M.P.2
Gracely, R.H.3
-
59
-
-
0030663691
-
Effect of CP101,606, a novel NR2B subunit antagonist of the N-methyl-D-aspartate receptor, on the volume of ischemic brain damage and cytotoxic brain edema after middle cerebral artery occlusion in the feline brain
-
DI X, BULLOCK R, WATSON J et al.: Effect of CP101,606, a novel NR2B subunit antagonist of the N-methyl-D-aspartate receptor, on the volume of ischemic brain damage and cytotoxic brain edema after middle cerebral artery occlusion in the feline brain. Stroke (1997) 28:2244-2251.
-
(1997)
Stroke
, vol.28
, pp. 2244-2251
-
-
Di, X.1
Bullock, R.2
Watson, J.3
-
60
-
-
0033392424
-
A double-blind, placebo-controled study of the safety, tolerability and pharmacokinetics of CP-101,606 in patients with a mild or moderate traumatic brain injury
-
MERCHANT R, BULLOCK MR, CARMACK CA et al.: A double-blind, placebo-controled study of the safety, tolerability and pharmacokinetics of CP-101,606 in patients with a mild or moderate traumatic brain injury. Ann. NY Acad. Sci. (1999) 890:42-50.
-
(1999)
Ann. NY Acad. Sci.
, vol.890
, pp. 42-50
-
-
Merchant, R.1
Bullock, M.R.2
Carmack, C.A.3
-
61
-
-
0033387727
-
An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral hemorrhage
-
BULLOCK MR, MERCHANT RE, CARMACK CA et al.: An open-label study of CP-101,606 in subjects with a severe traumatic head injury or spontaneous intracerebral hemorrhage. Ann. NY Acad Sci. (1999) 890:51-58.
-
(1999)
Ann. NY Acad. Sci.
, vol.890
, pp. 51-58
-
-
Bullock, M.R.1
Merchant, R.E.2
Carmack, C.A.3
-
62
-
-
0029991515
-
Neuroprotective effects of preischemia intraarterial magnesium sulfate in reversible focal cerebral ischemia
-
MARINOV MB, HARBAUGH KS, HOOPES PJ, PIKUS HJ, HARBAUGH RE: Neuroprotective effects of preischemia intraarterial magnesium sulfate in reversible focal cerebral ischemia. J. Neurosurg. (1996) 85:117-124.
-
(1996)
J. Neurosurg.
, vol.85
, pp. 117-124
-
-
Marinov, M.B.1
Harbaugh, K.S.2
Hoopes, P.J.3
Pikus, H.J.4
Harbaugh, R.E.5
-
63
-
-
0026091467
-
Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats
-
IZUMI Y, ROUSSEL S, PINARD E, SEYLAZ J: Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. (1991) 11:1025-1030.
-
(1991)
J. Cereb. Blood Flow Metab.
, vol.11
, pp. 1025-1030
-
-
Izumi, Y.1
Roussel, S.2
Pinard, E.3
Seylaz, J.4
-
64
-
-
0022005967
-
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex
-
HARRISON NL, SIMMONDS MA: Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. Br. J. Pharmacol. (1985) 84:381-368.
-
(1985)
Br. J. Pharmacol.
, vol.84
, pp. 381-368
-
-
Harrison, N.L.1
Simmonds, M.A.2
-
65
-
-
0031970836
-
Dose optimisation of intravenous magnesium sulfate after acute stroke
-
MUIR KW, LEES KR; Dose optimisation of intravenous magnesium sulfate after acute stroke. Stroke (1998) 29:918-923.
-
(1998)
Stroke
, vol.29
, pp. 918-923
-
-
Muir, K.W.1
Lees, K.R.2
-
66
-
-
0034468512
-
Design of the intravenous magnesium efficacy in acute stroke (IMAGES) trial
-
BRADFORD A, LEES K: Design of the intravenous magnesium efficacy in acute stroke (IMAGES) trial. Curr. Control Trials Cardiovasc. Med. (2000) 1:184-190.
-
(2000)
Curr. Control Trials Cardiovasc. Med.
, vol.1
, pp. 184-190
-
-
Bradford, A.1
Lees, K.2
-
67
-
-
0033819840
-
Dexanabimol (HU-211): A nonpsychotropic cannabinoid with neuroprotective properties
-
SHOHAMI E, MECHOULAM R: Dexanabimol (HU-211): a nonpsychotropic cannabinoid with neuroprotective properties. Drug Develop. Res. (2000) 50:211-215.
-
(2000)
Drug Develop. Res.
, vol.50
, pp. 211-215
-
-
Shohami, E.1
Mechoulam, R.2
-
68
-
-
0035906513
-
Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia
-
LAVIE G, TEICHNER A, SHOHAMI E, OVADIA H, LEKER RR: Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia. Brain Res. (2001) 901:195-201.
-
(2001)
Brain Res.
, vol.901
, pp. 195-201
-
-
Lavie, G.1
Teichner, A.2
Shohami, E.3
Ovadia, H.4
Leker, R.R.5
-
69
-
-
0036192049
-
Dexanabinol (HU-211) in the treatment of severe closed head injury: A randomized, placebo-controlled, Phase II clinical trial
-
KNOLLER N, LEVI L, SHOSHAN I et al.: Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, Phase II clinical trial. Crit. Care Med. (2002) 30:548-554.
-
(2002)
Crit. Care Med.
, vol.30
, pp. 548-554
-
-
Knoller, N.1
Levi, L.2
Shoshan, I.3
-
70
-
-
0345802290
-
DP-b99 a neuroprotective agent for cerebral ischemia
-
ANGEL I, KRAKOVSKY M, SHEMESH T, BEIT-YANNAI E, FRIEDMAN JE, KOZAK: DP-b99 a neuroprotective agent for cerebral ischemia. Biochem. Int. (2000) Nov/Dec:20-22.
-
(2000)
Biochem. Int.
, vol.NOV-DEC
, pp. 20-22
-
-
Angel, I.1
Krakovsky, M.2
Shemesh, T.3
Beit-Yannai, E.4
Friedman, J.E.5
Kozak6
-
71
-
-
0034712740
-
Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890CL
-
CARTER AJ, GRAUERT M, PSCHORN U et al.: Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890CL. Proc. Natl. Acad. Sci. (2000) 97:4944-4949.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 4944-4949
-
-
Carter, A.J.1
Grauert, M.2
Pschorn, U.3
-
72
-
-
0033028848
-
BIIR 561 CL: A novel combined antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties
-
WEISER T, BRENNER M, PALLUK R et al.: BIIR 561 CL: A novel combined antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties. J. Pharmacol. Exp. Therap. (1999) 289:1343-1349.
-
(1999)
J. Pharmacol. Exp. Therap.
, vol.289
, pp. 1343-1349
-
-
Weiser, T.1
Brenner, M.2
Palluk, R.3
-
73
-
-
0030580427
-
Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI
-
YENARI MA, PALMER JT, HUA SUN G et al.: Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI. Brain Res. (1996) 739:36-45.
-
(1996)
Brain Res.
, vol.739
, pp. 36-45
-
-
Yenari, M.A.1
Palmer, J.T.2
Hua Sun, G.3
-
74
-
-
0031039720
-
Selective blockade of N-type voltage-sensitive calcium channels protects against brain injury after transient focal cerebral ischemia in rats
-
BOWERSOX SS, SINGH T, LUTHER RR: Selective blockade of N-type voltage-sensitive calcium channels protects against brain injury after transient focal cerebral ischemia in rats. Brain Res. (1997) 747:343-347.
-
(1997)
Brain Res.
, vol.747
, pp. 343-347
-
-
Bowersox, S.S.1
Singh, T.2
Luther, R.R.3
-
76
-
-
0035951623
-
2+ channel blocker NS-7 I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats
-
2+ channel blocker NS-7 I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats. Brain Res. (2001) 890:162-169.
-
(2001)
Brain Res.
, vol.890
, pp. 162-169
-
-
Aoki, Y.1
Tamura, M.2
Itoh, Y.3
Ukai, Y.4
-
77
-
-
0035951624
-
2+ channel blocker NS-7 II. Effect on the cerebral infarction, behavioural and cognitive impairments at the chronic stage of permanent middle cerebral artery occlusion in rats
-
2+ channel blocker NS-7 II. Effect on the cerebral infarction, behavioural and cognitive impairments at the chronic stage of permanent middle cerebral artery occlusion in rats. Brain Res. (2001) 890:170-176.
-
(2001)
Brain Res.
, vol.890
, pp. 170-176
-
-
Tamura, M.1
Aoki, Y.2
Seto, T.3
Itoh, Y.4
Ukai, Y.5
-
78
-
-
0036082491
-
Characterization of the diarylether sulfonylester (-)-R-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties
-
MAULER F, MITTENDORF J, HORVATH E et al.: Characterization of the diarylether sulfonylester (-)-R-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties. J. Pharmacol. Exp. Therap. (2002) 302:359-368.
-
(2002)
J. Pharmacol. Exp. Therap.
, vol.302
, pp. 359-368
-
-
Mauler, F.1
Mittendorf, J.2
Horvath, E.3
-
80
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
CHAN P: Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. (2001) 21:2-14.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 2-14
-
-
Chan, P.1
-
81
-
-
0035949481
-
A radical approach to stroke therapy
-
MCCULLOCH J, DEWAR D: A radical approach to stroke therapy. Proc. Natl. Acad. Sci. (2001) 98:10989-10991.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 10989-10991
-
-
Mcculloch, J.1
Dewar, D.2
-
83
-
-
0036281518
-
Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils
-
JIN Y-J, MIMA T, RAICU V, PARK KC, SHIMIZU K: Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils. Neurosci. Res. (2002) 43:75-79.
-
(2002)
Neurosci. Res.
, vol.43
, pp. 75-79
-
-
Jin, Y.-J.1
Mima, T.2
Raicu, V.3
Park, K.C.4
Shimizu, K.5
-
84
-
-
0021185122
-
A novel biologically active selenoorganic compound-I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ51 (ebselen)
-
MULLER A, CADENAS E, GRAF P, SIES H: A novel biologically active selenoorganic compound-I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ51 (ebselen). Biochem. Pharmacol. (1984) 33:3235-3239.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 3235-3239
-
-
Muller, A.1
Cadenas, E.2
Graf, P.3
Sies, H.4
-
85
-
-
0034821411
-
Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia
-
IMAI H, MASAYASU H, DEWAR D, GRAHAM DI, MACRAE IM: Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke (2001) 32:2149-2154.
-
(2001)
Stroke
, vol.32
, pp. 2149-2154
-
-
Imai, H.1
Masayasu, H.2
Dewar, D.3
Graham, D.I.4
Macrae, I.M.5
-
86
-
-
0031963836
-
Ebselen in acute ischemic stroke
-
YAMAGUCHI T, SANO K, TAKAKURA K et al.: Ebselen in acute ischemic stroke. Stroke (1998) 29:12-17.
-
(1998)
Stroke
, vol.29
, pp. 12-17
-
-
Yamaguchi, T.1
Sano, K.2
Takakura, K.3
-
87
-
-
0033042957
-
Ebselen in acute middle cerebral artery occlusion: A placebo-controlled, double-blind clinical trial
-
OGAWA A, YOSHIMOTO T, KIKUCHI H et al.: Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial. Cerebrovasc. Dis. (1999) 9:112-118. Clinical trial showing efficacy of ebselen in acute stroke.
-
(1999)
Cerebrovasc. Dis.
, vol.9
, pp. 112-118
-
-
Ogawa, A.1
Yoshimoto, T.2
Kikuchi, H.3
-
89
-
-
0036152938
-
Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window
-
SYDSERFF SG, BORELLI AR, GREEN AR, CROSS AJ: Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window. Br. J. Pharmacol. (2002) 135:103-112.
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 103-112
-
-
Sydserff, S.G.1
Borelli, A.R.2
Green, A.R.3
Cross, A.J.4
-
90
-
-
0035154631
-
NXY-059, a free radical trapping agent, substantially lessens the functional disability resulting from cerebral ischaemia in a primate species
-
MARSHALL JWB, DUFFIN KJ, GREEN AR et al.: NXY-059, a free radical trapping agent, substantially lessens the functional disability resulting from cerebral ischaemia in a primate species. Stroke (2001) 32:190-198.
-
(2001)
Stroke
, vol.32
, pp. 190-198
-
-
Marshall, J.W.B.1
Duffin, K.J.2
Green, A.R.3
-
91
-
-
0034745231
-
Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke
-
LEES KR, SHARMA AK, BARER D et al.: Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke. Stroke (2001) 32:675-680.
-
(2001)
Stroke
, vol.32
, pp. 675-680
-
-
Lees, K.R.1
Sharma, A.K.2
Barer, D.3
-
92
-
-
0036263210
-
Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: Suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits
-
TATEISHI N, MORI T, KAGAMIISHI Y et al.: Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J. Cereb. Blood Flow Metab. (2002) 22:723-734.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 723-734
-
-
Tateishi, N.1
Mori, T.2
Kagamiishi, Y.3
-
93
-
-
0024452528
-
The pharmacology of dichloroacetate
-
STACPOOLE PW: The pharmacology of dichloroacetate. Metabolism (1989) 38:1124-1144.
-
(1989)
Metabolism
, vol.38
, pp. 1124-1144
-
-
Stacpoole, P.W.1
-
94
-
-
0028854668
-
Clinical correlates of proton magnetic resonance spectroscopy findings after acute cerebral infarction
-
GRAHAM GD, KALVACH P, BLAMIRE AM, BRASS LM, FAYAD PB, PRICHARD JW: Clinical correlates of proton magnetic resonance spectroscopy findings after acute cerebral infarction. Stroke (1995) 26:225-229.
-
(1995)
Stroke
, vol.26
, pp. 225-229
-
-
Graham, G.D.1
Kalvach, P.2
Blamire, A.M.3
Brass, L.M.4
Fayad, P.B.5
Prichard, J.W.6
-
95
-
-
0029869446
-
Protective effect of dichloroacetate in a rat model of forebrain ischemia
-
PEELING J, SUTHERLAND G, BROWN RA, CURRY S: Protective effect of dichloroacetate in a rat model of forebrain ischemia. Neurosci. Lett. (1996) 208:21-24.
-
(1996)
Neurosci. Lett.
, vol.208
, pp. 21-24
-
-
Peeling, J.1
Sutherland, G.2
Brown, R.A.3
Curry, S.4
-
96
-
-
0034649386
-
MR spectroscopy study of dichloroacetate treatment after ischemic stroke
-
GRAHAM GD, BARLER PB, BROOKS WM et al.: MR spectroscopy study of dichloroacetate treatment after ischemic stroke. Neurology (2000) 55:1376-1378.
-
(2000)
Neurology
, vol.55
, pp. 1376-1378
-
-
Graham, G.D.1
Barler, P.B.2
Brooks, W.M.3
-
97
-
-
0035002174
-
Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders
-
TARNOPOLSKY MA, BEAL MF: Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders. Ann. Neurol. (2001) 49:561-574.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 561-574
-
-
Tarnopolsky, M.A.1
Beal, M.F.2
-
98
-
-
0030928225
-
Pharmacology of neurotrophic factors
-
HEFTI F: Pharmacology of neurotrophic factors. Ann. Rev. Pharmacol. Toxicol. (1997) 37:239-267. Overview of preclinical and clinical data for neurotrophic factors in peripheral and CNS diseases.
-
(1997)
Ann. Rev. Pharmacol. Toxicol.
, vol.37
, pp. 239-267
-
-
Hefti, F.1
-
99
-
-
0036968150
-
Fiblast (trafermin) in acute stroke: Results of the European-Australine Phase II/III safety and efficacy trial
-
BOGOUSSLAVSKY J, VICTOR SJ, SALINAS EO et al.: Fiblast (trafermin) in acute stroke: results of the European-Australine Phase II/III safety and efficacy trial. Cerebrovasc. Dis. (2002) 14:239-251.
-
(2002)
Cerebrovasc. Dis.
, vol.14
, pp. 239-251
-
-
Bogousslavsky, J.1
Victor, S.J.2
Salinas, E.O.3
-
100
-
-
0032873417
-
Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors
-
SEMKOVA I, KRIEGLSTEIN J: Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors. Brain Res. Rev. (1999) 30:176-188.
-
(1999)
Brain Res. Rev.
, vol.30
, pp. 176-188
-
-
Semkova, I.1
Krieglstein, J.2
-
101
-
-
0030479204
-
Pituitary adenylate cydase-activating polypeptide (PACAP) is a regulator of astrocytes: PACAP stimulates proliferation and production of inter-leukin 6 (IL-6), but not nerve growth factor (NGF), in cultured rat astrocyte
-
TATSUNO I, MORIO H, TANAKA T et al.: Pituitary adenylate cydase-activating polypeptide (PACAP) is a regulator of astrocytes: PACAP stimulates proliferation and production of inter-leukin 6 (IL-6), but not nerve growth factor (NGF), in cultured rat astrocyte. Ann. NY Acad. Sci. (1996) 805:482-488.
-
(1996)
Ann. NY Acad. Sci.
, vol.805
, pp. 482-488
-
-
Tatsuno, I.1
Morio, H.2
Tanaka, T.3
-
102
-
-
0034035403
-
Delayed systemic administration of PACAP38 is neuroprotective in transient middle cerebral artery occlusion in the rat
-
REGLODI D, SOMOGYVARI-VIGH A, VIGH S et al.: Delayed systemic administration of PACAP38 is neuroprotective in transient middle cerebral artery occlusion in the rat. Stroke (2000) 31:1411-1417.
-
(2000)
Stroke
, vol.31
, pp. 1411-1417
-
-
Reglodi, D.1
Somogyvari-Vigh, A.2
Vigh, S.3
-
103
-
-
0036315818
-
NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo
-
DAGO L, BONDE C, PETERS D et al.: NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo. J. Neurochem. (2002) 81:17-24.
-
(2002)
J. Neurochem.
, vol.81
, pp. 17-24
-
-
Dago, L.1
Bonde, C.2
Peters, D.3
-
105
-
-
0035951899
-
1A receptor agonists possessing 1,4-benzoxazepine scaffold exhibit highly potent anti-ischemic effects
-
1A receptor agonists possessing 1,4-benzoxazepine scaffold exhibit highly potent anti-ischemic effects. Bioorg. Med. Chem. Lett. (2001) 11:595-598.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 595-598
-
-
Kamei, K.1
Maeda, N.2
Ogino, R.3
-
107
-
-
4243814865
-
The neuroprotectant BAY X 3702 in acute ischemic stroke: BRAINS
-
TEAL P, SILVER F, GROTTA J, SIMARD D: The neuroprotectant BAY X 3702 in acute ischemic stroke: BRAINS. Neurology (1999) 52(Suppl. 2):A383-A384.
-
(1999)
Neurology
, vol.52
, Issue.SUPPL. 2
-
-
Teal, P.1
Silver, F.2
Grotta, J.3
Simard, D.4
-
108
-
-
0038029666
-
Repinotan: An innovative Phase III design in stroke
-
TEAL P, ROMBOUT F, WEBER H et al.: Repinotan: an innovative Phase III design in stroke. Stroke (2001) 31:2811.
-
(2001)
Stroke
, vol.31
, pp. 2811
-
-
Teal, P.1
Rombout, F.2
Weber, H.3
-
109
-
-
0033918122
-
Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia
-
PHILLIPS JB, WILLIAMS AJ, ADAMS J, ELLIOTT PJ, TORTELLA FC: Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke (2000) 31:1686-1693.
-
(2000)
Stroke
, vol.31
, pp. 1686-1693
-
-
Phillips, J.B.1
Williams, A.J.2
Adams, J.3
Elliott, P.J.4
Tortella, F.C.5
-
110
-
-
0030957283
-
Endogenous intelieukin-1 receptor antagonist is neuroprotective
-
LODDICK SA, WONG M-L, BONGIORNO PB et al.: Endogenous intelieukin-1 receptor antagonist is neuroprotective. Eur. J. Pharmacol. (1997) 234:211-215.
-
(1997)
Eur. J. Pharmacol.
, vol.234
, pp. 211-215
-
-
Loddick, S.A.1
Wong, M.-L.2
Bongiorno, P.B.3
-
111
-
-
0030976856
-
Tumor necrosis factor-α. A mediator of focal ischemic brain injury
-
BARONE FC, ARVIN B, WHITE RF et al.: Tumor necrosis factor-α. A mediator of focal ischemic brain injury. Stroke (1997) 28:1233-1244.
-
(1997)
Stroke
, vol.28
, pp. 1233-1244
-
-
Barone, F.C.1
Arvin, B.2
White, R.F.3
-
112
-
-
0032850020
-
p38 MAPK signalling cascades in inflammatory disease
-
HERLAAR E, BROWN Z: p38 MAPK signalling cascades in inflammatory disease. Mol. Med. Today (1999) 5:439-447.
-
(1999)
Mol. Med. Today
, vol.5
, pp. 439-447
-
-
Herlaar, E.1
Brown, Z.2
-
113
-
-
0035895803
-
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia
-
LEGOS JL, ERHARDT JA, WHITE RF et al.: SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia. Brain Res. (2001) 892:70-77.
-
(2001)
Brain Res.
, vol.892
, pp. 70-77
-
-
Legos, J.L.1
Erhardt, J.A.2
White, R.F.3
-
114
-
-
0036244550
-
Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
-
CHONG ZZ, KANG J-Q, MAIESE K: Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades. J. Cereb. Blood Flow Metab. (2002) 22:503-514.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 503-514
-
-
Chong, Z.Z.1
Kang, J.-Q.2
Maiese, K.3
-
115
-
-
0034641710
-
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
-
BRINES ML, GHEZZI P, KEENAN S et al.: Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc. Natl. Acad. Sci. (2000) 97:10526-10531.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 10526-10531
-
-
Brines, M.L.1
Ghezzi, P.2
Keenan, S.3
-
116
-
-
0036705708
-
Erythropoietin therapy for acute stroke is both safe and beneficial
-
EHRENREICH H, HASSELBLATT M, DEMBOWSKI C et al.: Erythropoietin therapy for acute stroke is both safe and beneficial. Mol. Med. (2002) 8:495-505.
-
(2002)
Mol. Med.
, vol.8
, pp. 495-505
-
-
Ehrenreich, H.1
Hasselblatt, M.2
Dembowski, C.3
-
117
-
-
0034952544
-
Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin
-
WIESSNER C, ALLEGRINI PR, EKATODRAMIS D et al.: Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin. J. Cereb. Blood Flow Metab. (2001) 21:857-864.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 857-864
-
-
Wiessner, C.1
Allegrini, P.R.2
Ekatodramis, D.3
-
118
-
-
0037075272
-
Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin
-
CASADEVALL N, NATAF J, VIRON B et al.: Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N. Engl. J. Med. (2002) 346:469-475.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 469-475
-
-
Casadevall, N.1
Nataf, J.2
Viron, B.3
-
119
-
-
0035168889
-
Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke
-
MORRIS DC, ZHANG L, ZHANG ZG et al.: Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke. Stroke (2001) 32:2635-2640.
-
(2001)
Stroke
, vol.32
, pp. 2635-2640
-
-
Morris, D.C.1
Zhang, L.2
Zhang, Z.G.3
-
120
-
-
0345561549
-
Synergistic effects of a combination of low-dose basic fibroblast growth factor and citicoline after temporary experimental focal ischemia
-
SCHABITZ WR, FUHAI L, IRIE K et al.: Synergistic effects of a combination of low-dose basic fibroblast growth factor and citicoline after temporary experimental focal ischemia. Stroke (1999) 30:427-432.
-
(1999)
Stroke
, vol.30
, pp. 427-432
-
-
Schabitz, W.R.1
Fuhai, L.2
Irie, K.3
-
121
-
-
0343052709
-
Synergistic effects of citicoline and MK-801 in temporary experimental ischemia in rats
-
ONAL MZ, FUHAI L, TATLISUMAK T et al.: Synergistic effects of citicoline and MK-801 in temporary experimental ischemia in rats. Stroke (1997) 28:1060-1065.
-
(1997)
Stroke
, vol.28
, pp. 1060-1065
-
-
Onal, M.Z.1
Fuhai, L.2
Tatlisumak, T.3
-
122
-
-
0002639298
-
Results of clinical studies with donepezil in vascular dementia
-
PRATT RD, PERDOMO CA: Results of clinical studies with donepezil in vascular dementia. Am. J. Geriatr. Psych. (2002) 10(Suppl.):S34-S41.
-
(2002)
Am. J. Geriatr. Psych.
, vol.10
, Issue.SUPPL.
-
-
Pratt, R.D.1
Perdomo, C.A.2
-
123
-
-
0036636375
-
An open-label pilot study comparing rivastigmine and low-dose aspirin for the treatment of symptoms specific to patients with subcortical vascular dementia
-
MORETTI R, TORRE P, ANTONELLO RM et al.: An open-label pilot study comparing rivastigmine and low-dose aspirin for the treatment of symptoms specific to patients with subcortical vascular dementia. Curr. Therap. Res. (2002) 63:443-458.
-
(2002)
Curr. Therap. Res.
, vol.63
, pp. 443-458
-
-
Moretti, R.1
Torre, P.2
Antonello, R.M.3
-
124
-
-
0007785580
-
Galantamine shows promising results in Alzheimer's disease with cerebrovascular components and probable vascular dementia (preliminary results)
-
BULLOCK R, LILLENFELD S: Galantamine shows promising results in Alzheimer's disease with cerebrovascular components and probable vascular dementia (preliminary results). J. Neurosci. (2001) 187(Suppl. 1)S59.
-
(2001)
J. Neurosci.
, vol.187
, Issue.SUPPL. 1
-
-
Bullock, R.1
Lillenfeld, S.2
-
125
-
-
0027939918
-
Effect of piracetam on recovery and rehabilitation after stroke: A double-blind, placebo-controlled study
-
ENDERBY P, BROECKX J, HOSPERS W, SCHILDERMANS F, DEBERDT W: Effect of piracetam on recovery and rehabilitation after stroke: a double-blind, placebo-controlled study. Clin. Neuropharmacol. (1994) 17:320-331.
-
(1994)
Clin. Neuropharmacol.
, vol.17
, pp. 320-331
-
-
Enderby, P.1
Broeckx, J.2
Hospers, W.3
Schildermans, F.4
Deberdt, W.5
-
126
-
-
0033811164
-
Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients
-
KESSLER J, THIEL A, KARBE H, HEISS WD: Piracetam improves activated blood flow and facilitates rehabilitation of poststroke aphasic patients. Stroke (2000) 31:2112-2116.
-
(2000)
Stroke
, vol.31
, pp. 2112-2116
-
-
Kessler, J.1
Thiel, A.2
Karbe, H.3
Heiss, W.D.4
-
127
-
-
0031869029
-
Piracetam in the treatment of acute stroke
-
ORGOGOZO JM: Piracetam in the treatment of acute stroke. CNS Drugs (1998) 9(Suppl. 1):41-49.
-
(1998)
CNS Drugs
, vol.9
, Issue.SUPPL. 1
, pp. 41-49
-
-
Orgogozo, J.M.1
-
128
-
-
0034084071
-
Enhancing recovery after stroke with noradrenergic pharmacotherapy: A new frontier?
-
GLADSTONE DJ, BLACK SE: Enhancing recovery after stroke with noradrenergic pharmacotherapy: a new frontier? Can. J. Neurol. Sci. (2000) 27:97-105. Review of animal and clinical trials of the ability of amphetamine to promote stroke recovery
-
(2000)
Can. J. Neurol. Sci.
, vol.27
, pp. 97-105
-
-
Gladstone, D.J.1
Black, S.E.2
-
129
-
-
0033961763
-
Effects of amphetamines and small related molecules on recovery after stroke in animals and man
-
GOLDSTEIN LB: Effects of amphetamines and small related molecules on recovery after stroke in animals and man. Neurepharmacol. (2000) 39:852-859. Review of effects of drugs which modulate levels of central neurotransmitters on functional reeovery in animal models of focal brain injury
-
(2000)
Neurepharmacol.
, vol.39
, pp. 852-859
-
-
Goldstein, L.B.1
-
130
-
-
0031761434
-
Enhanced neocortical neural sprouting, synaptogenesis, and behavioural recovery with D-amphetamine therapy after neocortical infarction in rats
-
STROEMER RP, KENT TA, HULSEBOSCH CE: Enhanced neocortical neural sprouting, synaptogenesis, and behavioural recovery with D-amphetamine therapy after neocortical infarction in rats. Stroke (1998) 29:2381-2395. Demonstration of the ability of amphetamine to promote plasticity and functional recovery in a rat model of stroke.
-
(1998)
Stroke
, vol.29
, pp. 2381-2395
-
-
Stroemer, R.P.1
Kent, T.A.2
Hulsebosch, C.E.3
-
131
-
-
0023693269
-
Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients
-
CRISOSTOMO EA, DUNCAN PW, PROPST M, DAWSON DV, DAVIS JN: Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients. Ann. Neurol. (1988) 23:94-97.
-
(1988)
Ann. Neurol.
, vol.23
, pp. 94-97
-
-
Crisostomo, E.A.1
Duncan, P.W.2
Propst, M.3
Dawson, D.V.4
Davis, J.N.5
-
132
-
-
0028867303
-
Amphetamine paired with physical therapy accelerates motor recovery after stroke
-
WALKER-BATSON D, SMITH P, CURTIS S, UNWIN H, GREENLESS R: Amphetamine paired with physical therapy accelerates motor recovery after stroke. Stroke (1995) 26:2254-2259.
-
(1995)
Stroke
, vol.26
, pp. 2254-2259
-
-
Walker-Batson, D.1
Smith, P.2
Curtis, S.3
Unwin, H.4
Greenless, R.5
-
134
-
-
0001304445
-
Effect of dextroamphetamine on motor recovery after stroke
-
REDING M, SOLOMOM B, BORUCKI S: Effect of dextroamphetamine on motor recovery after stroke. Neurology (1995) 45(Suppl. 4):S01.
-
(1995)
Neurology
, vol.45
, Issue.SUPPL. 4
-
-
Reding, M.1
Solomom, B.2
Borucki, S.3
-
135
-
-
0034770073
-
A double-blind placebo-controlled study of the effects of amphetamine and physiotherapy after stroke
-
SONDE L, NORDSTROM M, NILSSON C-G, LOKK J, VIITANEN M: A double-blind placebo-controlled study of the effects of amphetamine and physiotherapy after stroke. Cerebrovasc. Dis. (2001) 12:253-257.
-
(2001)
Cerebrovasc. Dis.
, vol.12
, pp. 253-257
-
-
Sonde, L.1
Nordstrom, M.2
Nilsson, C.-G.3
Lokk, J.4
Viitanen, M.5
-
136
-
-
0029972042
-
Effects of fluoxetine and maprotiline on functional recovery in poststroke haemiplegic patients undergoing rehabilitation therapy
-
DAM M, TONIN P, DEBONI A et al.: Effects of fluoxetine and maprotiline on functional recovery in poststroke haemiplegic patients undergoing rehabilitation therapy. Stroke (1996) 27:1211-1214.
-
(1996)
Stroke
, vol.27
, pp. 1211-1214
-
-
Dam, M.1
Tonin, P.2
Deboni, A.3
-
137
-
-
0031656504
-
Methylphenidate in early poststroke recovery: A double-blind, placebo-controlled study
-
GRADE C, REDFORD B, CHROSTOWSKI J et al.: Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study. Arch. Phys. Med. Rehabil. (1998) 79:1047-1050.
-
(1998)
Arch. Phys. Med. Rehabil.
, vol.79
, pp. 1047-1050
-
-
Grade, C.1
Redford, B.2
Chrostowski, J.3
-
138
-
-
0035828396
-
Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: A prospective, randomised, double-blind study
-
SCHEIDTMANN K, FRIES W, MULLER F, KOENIG E: Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: a prospective, randomised, double-blind study. Lancet (2001) 358:787-790.
-
(2001)
Lancet
, vol.358
, pp. 787-790
-
-
Scheidtmann, K.1
Fries, W.2
Muller, F.3
Koenig, E.4
-
139
-
-
0030953487
-
Recovery and repair issues after stroke from the scientific perspective
-
SEIL FJ: Recovery and repair issues after stroke from the scientific perspective. Curr. Opin. Neurol. (1997) 10:49-51.
-
(1997)
Curr. Opin. Neurol.
, vol.10
, pp. 49-51
-
-
Seil, F.J.1
-
140
-
-
0029991601
-
Intracisternal basic fibroblast growth factor (bFGF) enhances behavioural recovery following focal cerebral infarction in the rat
-
KAWAMATA T, ALEXIS AE, DIETRICH D, FINKLESTEIN SP: Intracisternal basic fibroblast growth factor (bFGF) enhances behavioural recovery following focal cerebral infarction in the rat. J. Cereb. Blood Flow Metab. (1996) 16:542-547.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 542-547
-
-
Kawamata, T.1
Alexis, A.E.2
Dietrich, D.3
Finklestein, S.P.4
-
141
-
-
0032507636
-
Intracisternal osteogenic protein-1 enhances functional recovery following focal stroke
-
KAWAMATA T, REN JM, CHAN TCK, CHARETTE M, FINKLESTEIN SP: Intracisternal osteogenic protein-1 enhances functional recovery following focal stroke. Neuroreport (1998) 9:1441-1445.
-
(1998)
Neuroreport
, vol.9
, pp. 1441-1445
-
-
Kawamata, T.1
Ren, J.M.2
Chan, T.C.K.3
Charette, M.4
Finklestein, S.P.5
-
142
-
-
0037015059
-
Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
-
JIN K, ZHU Y, SUN Y, OU MAO X, XIE P, GREENBERG DA: Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc. Natl. Acad. Sci. (2002) 99:11946-11950.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 11946-11950
-
-
Jin, K.1
Zhu, Y.2
Sun, Y.3
Ou Mao, X.4
Xie, P.5
Greenberg, D.A.6
-
143
-
-
0033797255
-
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
-
ZHANG ZG, ZHANG L, JIANG Q et al.: VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J. Clin. Invest. (2000) 106:829-838.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 829-838
-
-
Zhang, Z.G.1
Zhang, L.2
Jiang, Q.3
-
144
-
-
0035253244
-
Repulsive factors and axon regeneration in the CNS
-
FOURNIER A, STRITTMATTER SM: Repulsive factors and axon regeneration in the CNS. Curr. Opin. Neurobiol. (2001) 11:89-94. Review of factors which inhibit axonal regeneration in CNS.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 89-94
-
-
Fournier, A.1
Strittmatter, S.M.2
-
145
-
-
0037182860
-
Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth
-
WANG KC, KOPRIVICA V, SIVASANKARAN R et al.: Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature (2002) 417:941-944.
-
(2002)
Nature
, vol.417
, pp. 941-944
-
-
Wang, K.C.1
Koprivica, V.2
Sivasankaran, R.3
-
146
-
-
0035905799
-
Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
-
FOURNIER AE, GRANDPRE T, STRITTMATTER SM et al.: Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature (2001) 409:341-346.
-
(2001)
Nature
, vol.409
, pp. 341-346
-
-
Fournier, A.E.1
Grandpre, T.2
Strittmatter, S.M.3
-
147
-
-
18444379933
-
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth
-
DOMENICONI M, CAO Z, SPENCER T et al.: Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. Neuron (2002) 35:283-290.
-
(2002)
Neuron
, vol.35
, pp. 283-290
-
-
Domeniconi, M.1
Cao, Z.2
Spencer, T.3
-
148
-
-
0037198689
-
Nogo-66 receptor antagonist peptide promotes axonal regeneration
-
GRANDPRE T, LI S, STRITTMATTER SM: Nogo-66 receptor antagonist peptide promotes axonal regeneration. Nature (2002) 417:547-551.
-
(2002)
Nature
, vol.417
, pp. 547-551
-
-
Grandpre, T.1
Li, S.2
Strittmatter, S.M.3
-
149
-
-
0037071537
-
The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho
-
YAMASHITA T, HIGUCHI H, TOHYAMA M: The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. J. Cell Biol. (2002) 157:565-570.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 565-570
-
-
Yamashita, T.1
Higuchi, H.2
Tohyama, M.3
-
150
-
-
0035827606
-
Myelin-associated glycoprotein interacts with ganglioside GT1b
-
VINSON M, STRIJBOS PJLM, ROWLES A et al.: Myelin-associated glycoprotein interacts with ganglioside GT1b. J. Biol. Chem. (2001) 276:20280-20285.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20280-20285
-
-
Vinson, M.1
Strijbos, P.J.L.M.2
Rowles, A.3
-
151
-
-
0033152924
-
Signal transduction underlying growth cone guidance by diffusible factors
-
SONG H-J, POO M-M: Signal transduction underlying growth cone guidance by diffusible factors. Curr. Opin. Neurobiol. (1999) 9:355-363.
-
(1999)
Curr. Opin. Neurobiol.
, vol.9
, pp. 355-363
-
-
Song, H.-J.1
Poo, M.-M.2
-
152
-
-
0035093839
-
Emerging roles for semaphorins in neural regeneration
-
PASTERKAMP RJ, VERHAAGEN J: Emerging roles for semaphorins in neural regeneration. Brain Res. Rev. (2001) 35:36-54.
-
(2001)
Brain Res. Rev.
, vol.35
, pp. 36-54
-
-
Pasterkamp, R.J.1
Verhaagen, J.2
-
153
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
HALL A: Rho GTPases and the actin cytoskeleton. Science (1998) 279:509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
154
-
-
0033230625
-
Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
-
YAMASHITA T, TUCKER KL, BARDE YA: Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron (1999) 24:585-593.
-
(1999)
Neuron
, vol.24
, pp. 585-593
-
-
Yamashita, T.1
Tucker, K.L.2
Barde, Y.A.3
-
155
-
-
0036469263
-
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism
-
NEUMANN H, SCHWEIGREITER R, YAMASHITA T et al.: Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism. J. Neurosci. (2002) 22:854-862.
-
(2002)
J. Neurosci.
, vol.22
, pp. 854-862
-
-
Neumann, H.1
Schweigreiter, R.2
Yamashita, T.3
-
156
-
-
0030809301
-
Rac1 mediares collapsin-1-induced growth cone collapse
-
JIN Z, STRITTMATTER SM: Rac1 mediares collapsin-1-induced growth cone collapse. J. Neurosci. (1997) 17:6256-6263.
-
(1997)
J. Neurosci.
, vol.17
, pp. 6256-6263
-
-
Jin, Z.1
Strittmatter, S.M.2
-
157
-
-
0033198033
-
Inactivation of Rho signalling pathway promotes CNS axon regeneration
-
LEHMANN M, FOURNIER A, SELLES-NAVARRO et al.: Inactivation of Rho signalling pathway promotes CNS axon regeneration. J. Neurosci. (1999) 19:7537-7547.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7537-7547
-
-
Lehmann, M.1
Fournier, A.2
Selles-Navarro3
-
158
-
-
0036703599
-
Rho signalling pathway targeted to promote spinal cord repair
-
DERGHAM P, ELLEZAM B, ESSAGIAN C et al.: Rho signalling pathway targeted to promote spinal cord repair. J. Neurosci. (2002) 22:6570-6577.
-
(2002)
J. Neurosci.
, vol.22
, pp. 6570-6577
-
-
Dergham, P.1
Ellezam, B.2
Essagian, C.3
-
159
-
-
0028115777
-
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
-
SCHNELL L, SCHNEIDER R, KILBECK R et al.: Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature (1994) 367:170-173.
-
(1994)
Nature
, vol.367
, pp. 170-173
-
-
Schnell, L.1
Schneider, R.2
Kilbeck, R.3
-
160
-
-
0036779764
-
Major on-going stroke trials
-
NO AUTHORS LISTED: Major on-going stroke trials Stroke (2002) 33:2525-2535. Listing of current major stroke trials. Updated quarterly.
-
(2002)
Stroke
, vol.33
, pp. 2525-2535
-
-
-
162
-
-
0035101898
-
Vitamin intervention for stroke prevention (VISP) trial: Rationale and design
-
SPENCE JD, HOWARD VJ, CHAMBLESS LE et al.: Vitamin intervention for stroke prevention (VISP) trial: rationale and design. Neuroepidemielogy (2001) 20:16-25.
-
(2001)
Neuroepidemielogy
, vol.20
, pp. 16-25
-
-
Spence, J.D.1
Howard, V.J.2
Chambless, L.E.3
-
163
-
-
0036187533
-
The VITATOPS (vitamins to prevent stroke) Trial: Rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke
-
BAKER RI, EIKELBOOM J, GELAVIS A et al.: The VITATOPS (vitamins to prevent stroke) Trial: rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke. Cerebrovasc. Dis. (2002) 13:120-126.
-
(2002)
Cerebrovasc. Dis.
, vol.13
, pp. 120-126
-
-
Baker, R.I.1
Eikelboom, J.2
Gelavis, A.3
-
164
-
-
0038029709
-
Neuroimaging, the ischaemic penumbra, and selection of patients for acute stroke therapy
-
DONNAN GA, DAVIS SM: Neuroimaging, the ischaemic penumbra, and selection of patients for acute stroke therapy. Lancet Neurol. (2002) 1:417-425.
-
(2002)
Lancet Neurol.
, vol.1
, pp. 417-425
-
-
Donnan, G.A.1
Davis, S.M.2
-
165
-
-
0036245040
-
Pharmacokinetics and brain uptake of biotinylated basic fibroblast growth factor conjugated to a blood-brain barrier drug delivery system
-
WU DF, SONG BW, VINTERS HV, PARDRIDGE WM: Pharmacokinetics and brain uptake of biotinylated basic fibroblast growth factor conjugated to a blood-brain barrier drug delivery system. J. Drug Targeting (2002) 10:239-245.
-
(2002)
J. Drug Targeting
, vol.10
, pp. 239-245
-
-
Wu, D.F.1
Song, B.W.2
Vinters, H.V.3
Pardridge, W.M.4
-
166
-
-
0033951941
-
Selfotel in acute ischemic stroke: Possible neurotoxic effects of an NMDA antagonist
-
DAVIS SM, LEES KR, ALBERS GW et al.: Selfotel in acute ischemic stroke: possible neurotoxic effects of an NMDA antagonist. Stroke (2000) 31:347-354.
-
(2000)
Stroke
, vol.31
, pp. 347-354
-
-
Davis, S.M.1
Lees, K.R.2
Albers, G.W.3
-
167
-
-
0035814418
-
Apdganel hydrochloride in acute ischemic stroke - A randomized controlled trial
-
ALBERS GV, GOLDSTEIN LB, HALL D, LESKO LM: Apdganel hydrochloride in acute ischemic stroke - a randomized controlled trial. JAMA (2001) 286:2673-2682.
-
(2001)
JAMA
, vol.286
, pp. 2673-2682
-
-
Albers, G.V.1
Goldstein, L.B.2
Hall, D.3
Lesko, L.M.4
-
168
-
-
0030666876
-
Cerestat and other NMDA antagonists in ischemic stroke
-
LEES KR: Cerestat and other NMDA antagonists in ischemic stroke. Neurology (1997) 49:S66-S69.
-
(1997)
Neurology
, vol.49
-
-
Lees, K.R.1
-
169
-
-
0032967750
-
Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke
-
ALBERS GW, CLARK WM, ATKINSON RP et al.: Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke. Stroke (1999) 30:508-513.
-
(1999)
Stroke
, vol.30
, pp. 508-513
-
-
Albers, G.W.1
Clark, W.M.2
Atkinson, R.P.3
-
170
-
-
0035804844
-
Glycine antagonist in neuroprotection for patients with acute stroke - GAIN Americas: A randomized controlled trial
-
SACCO RL, DEROSA JT, HALEY EC et al.: Glycine antagonist in neuroprotection for patients with acute stroke - GAIN Americas: a randomized controlled trial. JAMA (2001) 285:1719-1728.
-
(2001)
JAMA
, vol.285
, pp. 1719-1728
-
-
Sacco, R.L.1
Derosa, J.T.2
Haley, E.C.3
-
171
-
-
84939677173
-
Meta-analysis of oral nimodipine trials in acute ischemic stoke
-
MOHR JP, ORGOGOZO JM, HARRISON MJG et al.: Meta-analysis of oral nimodipine trials in acute ischemic stoke. Cerebrovasc Dis. (1994) 4:197-203.
-
(1994)
Cerebrovasc Dis.
, vol.4
, pp. 197-203
-
-
Mohr, J.P.1
Orgogozo, J.M.2
Harrison, M.J.G.3
-
172
-
-
0035134255
-
Very early nimodipine use in stroke (VENUS). A randomized, double-blind, placebo-controlled trial
-
HORN J, DE HAAN RJ, VERMEULEN M, LIMBURG M: Very early nimodipine use in stroke (VENUS). A randomized, double-blind, placebo-controlled trial. Stroke (2001) 32:461-465.
-
(2001)
Stroke
, vol.32
, pp. 461-465
-
-
Horn, J.1
De Haan, R.J.2
Vermeulen, M.3
Limburg, M.4
-
173
-
-
0033816426
-
Tirilazad mesylate in acute ischemic stroke: A systematic review
-
BATH PMW, IDDENDEN R, BATH FJ, ORGOGOZO JM: Tirilazad mesylate in acute ischemic stroke: a systematic review. Stroke (2000) 31:2257-2265.
-
(2000)
Stroke
, vol.31
, pp. 2257-2265
-
-
Bath, P.M.W.1
Iddenden, R.2
Bath, F.J.3
Orgogozo, J.M.4
-
174
-
-
0033766740
-
Lubeluzole in acute ischemic stroke treatment. A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo
-
DIENER HC, CORTENS M, FORD G et al.: Lubeluzole in acute ischemic stroke treatment. A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo. Stroke (2000) 31:2543-2551.
-
(2000)
Stroke
, vol.31
, pp. 2543-2551
-
-
Diener, H.C.1
Cortens, M.2
Ford, G.3
-
175
-
-
0032953495
-
Results of a randomized, controlled trial of domethiazole versus placebo in 1360 acute stroke patients
-
WAHLGREN NG, RANASINHA KW, ROSOLACCI T et al.: Results of a randomized, controlled trial of domethiazole versus placebo in 1360 acute stroke patients. Stroke (1999) 30:21-28.
-
(1999)
Stroke
, vol.30
, pp. 21-28
-
-
Wahlgren, N.G.1
Ranasinha, K.W.2
Rosolacci, T.3
-
176
-
-
0034034434
-
Cervene (Nalmefene) in acute ischemic stroke: Final results of a Phase III efficacy study
-
The Cervene stroke study investigators
-
CLARK WM, RAPS EC, TONG DC, KELLY RE: Cervene (Nalmefene) in acute ischemic stroke: final results of a Phase III efficacy study. The Cervene stroke study investigators. Stroke (2000) 31:1234-1239.
-
(2000)
Stroke
, vol.31
, pp. 1234-1239
-
-
Clark, W.M.1
Raps, E.C.2
Tong, D.C.3
Kelly, R.E.4
-
177
-
-
0030760430
-
A randomized dose-response trial of citicoline in acute ischemic stroke patients
-
CLARK WM, WARACH SJ, PETTIGREW LC et al.: A randomized dose-response trial of citicoline in acute ischemic stroke patients. Neurelogy (1997) 49:671-678.
-
(1997)
Neurelogy
, vol.49
, pp. 671-678
-
-
Clark, W.M.1
Warach, S.J.2
Pettigrew, L.C.3
-
178
-
-
0032709479
-
A randomized efficacy trial of citicoline in patients with acute ischemic stroke
-
CLARK WM, WARACH SJ, PETRIGREW LC et al.: A randomized efficacy trial of citicoline in patients with acute ischemic stroke. Stroke (1999) 30:2592-2597.
-
(1999)
Stroke
, vol.30
, pp. 2592-2597
-
-
Clark, W.M.1
Warach, S.J.2
Petrigrew, L.C.3
-
179
-
-
0035856456
-
A Phase III randomized efficacy trial of 2000mg citicoline in acute ischemic stroke patients
-
CLARK WM, WECHSLER LR, SABOUNJIAN LA, SCHWIDERSKI UE: A Phase III randomized efficacy trial of 2000mg citicoline in acute ischemic stroke patients. Neurology (2001) 57:1595-1602.
-
(2001)
Neurology
, vol.57
, pp. 1595-1602
-
-
Clark, W.M.1
Wechsler, L.R.2
Sabounjian, L.A.3
Schwiderski, U.E.4
-
180
-
-
0035940577
-
Use of anti-ICAM-1 therapy in ischemic stroke
-
SHERMAN DG, BEW A, EASTON JD et al.: Use of anti-ICAM-1 therapy in ischemic stroke. Neurology (2001) 57:1428-1440.
-
(2001)
Neurology
, vol.57
, pp. 1428-1440
-
-
Sherman, D.G.1
Bew, A.2
Easton, J.D.3
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