-
1
-
-
0030666876
-
Cerestat and other NMDA antagonists in ischemic stroke
-
Lees KR. Cerestat and other NMDA antagonists in ischemic stroke. Neurology. 1997;49(5 suppl 4):S66-S69.
-
(1997)
Neurology
, vol.49
, Issue.5 SUPPL. 4
-
-
Lees, K.R.1
-
2
-
-
0005877150
-
Selfotel (CGS.5): The preliminary clinical experience
-
Krieglstein J, Oberpichler-Schwenk H, eds. Stuttgart, Germany: Wissenschaftliche Verlagsgesellschaft mbH
-
Markabi S. Selfotel (CGS.5): The preliminary clinical experience. In: Krieglstein J, Oberpichler-Schwenk H, eds. Pharmacology of Cerebral Ischemia. Stuttgart, Germany: Wissenschaftliche Verlagsgesellschaft mbH; 1994:635-642.
-
(1994)
Pharmacology of Cerebral Ischemia
, pp. 635-642
-
-
Markabi, S.1
-
3
-
-
0028921447
-
Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke: Results of a phase IIa randomized trial
-
Grotta J, Clark W, Coull B, Pettigrew LC, Mackay B, Goldstein LB, Meissner I, Murphy D, LaRue L. Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke: results of a phase IIa randomized trial. Stroke. 1995;26:602-605.
-
(1995)
Stroke
, vol.26
, pp. 602-605
-
-
Grotta, J.1
Clark, W.2
Coull, B.3
Pettigrew, L.C.4
Mackay, B.5
Goldstein, L.B.6
Meissner, I.7
Murphy, D.8
Larue, L.9
-
5
-
-
0025309389
-
N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism
-
Simon R, Shiraishi K. N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism. Ann Neurol. 1990;27:606-611.
-
(1990)
Ann Neurol.
, vol.27
, pp. 606-611
-
-
Simon, R.1
Shiraishi, K.2
-
6
-
-
0027310151
-
Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP-40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study
-
Sauer D, Allegrini PR, Cosenti A, Pataki A, Amacker H, Fagg GE. Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP-40116 in a rat model of focal cerebral ischemia: an in vivo magnetic resonance imaging study. J Cereb Blood Flow Metab. 13:595-602.
-
J Cereb Blood Flow Metab.
, vol.13
, pp. 595-602
-
-
Sauer, D.1
Allegrini, P.R.2
Cosenti, A.3
Pataki, A.4
Amacker, H.5
Fagg, G.E.6
-
7
-
-
0343843198
-
The effects of CGS-19755 in rat focal cerebral ischemia produced by tandem ipsilateral common carotid artery and middle cerebral artery occlusion
-
Abstract
-
Simmonds J, Sailer T, Moyer J. The effects of CGS-19755 in rat focal cerebral ischemia produced by tandem ipsilateral common carotid artery and middle cerebral artery occlusion. Soc Neurosci Abstr. 1993;19:1647. Abstract.
-
(1993)
Soc Neurosci Abstr.
, vol.19
, pp. 1647
-
-
Simmonds, J.1
Sailer, T.2
Moyer, J.3
-
8
-
-
0027300760
-
Delayed therapy of experimental ischemia with competitive N-methyl-D-aspartate antagonists in rabbits
-
Madden K, Clark W, Zivin J. Delayed therapy of experimental ischemia with competitive N-methyl-D-aspartate antagonists in rabbits. Stroke. 1993;24:1068-1071.
-
(1993)
Stroke
, vol.24
, pp. 1068-1071
-
-
Madden, K.1
Clark, W.2
Zivin, J.3
-
9
-
-
0025992317
-
The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia
-
Takizawa S, Hogan M, Hakim A. The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia. J Cereb Blood Flow Metab. 1991;11:786-793.
-
(1991)
J Cereb Blood Flow Metab.
, vol.11
, pp. 786-793
-
-
Takizawa, S.1
Hogan, M.2
Hakim, A.3
-
10
-
-
70450195021
-
Functional evaluation: The Barthel Index
-
Mahoney FI, and Barthel DW. Functional evaluation: the Barthel Index. Md State Med J. 1965;61-65.
-
(1965)
Md State Med J.
, pp. 61-65
-
-
Mahoney, F.I.1
Barthel, D.W.2
-
11
-
-
0024328055
-
Measurements of acute cerebral infarction: A clinical examination scale
-
Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Hertzberg V, Rorick M, Moomaw CJ, Walker M. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989;20:864-870.
-
(1989)
Stroke
, vol.20
, pp. 864-870
-
-
Brott, T.1
Adams H.P., Jr.2
Olinger, C.P.3
Marler, J.R.4
Barsan, W.G.5
Biller, J.6
Spilker, J.7
Holleran, R.8
Eberle, R.9
Hertzberg, V.10
Rorick, M.11
Moomaw, C.J.12
Walker, M.13
-
12
-
-
0021970991
-
Multicenter Trial of Hemodilution in Ischemic Stroke: Background and study protocol
-
Scandinavian Stroke Study Group. Multicenter Trial of Hemodilution in Ischemic Stroke: background and study protocol. Stroke. 1985;16:881-890.
-
(1985)
Stroke
, vol.16
, pp. 881-890
-
-
-
14
-
-
0343472092
-
Termination of acute stroke studies involving Selfotel treatment
-
Letter
-
Davis SM, Albers GW, Diener, Lees KR, Norris J (ASSIST Steering Committee). Termination of acute stroke studies involving Selfotel treatment. Lancet. 1997;349:32. Letter.
-
(1997)
Lancet
, vol.349
, pp. 32
-
-
Davis, S.M.1
Albers, G.W.2
Diener3
Lees, K.R.4
Norris, J.5
-
15
-
-
0028870990
-
Safety, tolerability, and pharmacokinetics of the N-methyl-D-aspartate antagonist dextrorphan in patients with acute stroke
-
Albers GW, Atkinson RP, Kelley RE, Rosenbaum DM. Safety, tolerability, and pharmacokinetics of the N-methyl-D-aspartate antagonist dextrorphan in patients with acute stroke. Stroke. 1995;26:254-258.
-
(1995)
Stroke
, vol.26
, pp. 254-258
-
-
Albers, G.W.1
Atkinson, R.P.2
Kelley, R.E.3
Rosenbaum, D.M.4
-
16
-
-
0027474565
-
Effects of a novel MNDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI
-
Minematsu K, Fisher M, Li L, Davis MA, Knapp AG, Cotter RE, McBurney RN, Sotak CH. Effects of a novel MNDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology. 1993;43:397-403.
-
(1993)
Neurology
, vol.43
, pp. 397-403
-
-
Minematsu, K.1
Fisher, M.2
Li, L.3
Davis, M.A.4
Knapp, A.G.5
Cotter, R.E.6
McBurney, R.N.7
Sotak, C.H.8
-
17
-
-
0000105003
-
Cerestat (CNS 1102), a non-competitive NMDA antagonist, in ischemic stroke patients: Dose-escalating safety study
-
for CNS 1102-003 Investigators
-
Fisher M, for CNS 1102-003 Investigators. Cerestat (CNS 1102), a non-competitive NMDA antagonist, in ischemic stroke patients: dose-escalating safety study. Cerebrovasc Dis. 1994;4:245.
-
(1994)
Cerebrovasc Dis.
, vol.4
, pp. 245
-
-
Fisher, M.1
-
18
-
-
0000611086
-
Cerestat (aptiganel hydrochloride) in the treatment of acute ischemic stroke: Results of a phase II trial
-
Abstract
-
Edwards D, and the CNS 1102-008 Study Group. Cerestat (aptiganel hydrochloride) in the treatment of acute ischemic stroke: results of a phase II trial. Neurology. 1996;46:A424. Abstract.
-
(1996)
Neurology
, vol.46
-
-
Edwards, D.1
-
19
-
-
0000874835
-
A pivotal safety and efficacy study of Cerestat™ (Aptiganel HCL/CNS) in acute ischemic stroke
-
Abstract
-
Turrini R. A pivotal safety and efficacy study of Cerestat™ (Aptiganel HCL/CNS) in acute ischemic stroke. Stroke. 1996;27:173. Abstract.
-
(1996)
Stroke
, vol.27
, pp. 173
-
-
Turrini, R.1
-
20
-
-
0030952985
-
Pharmacological treatment of acute stroke
-
Wahlgren NG. Pharmacological treatment of acute stroke. Cerebrovasc Dis. 1997;7:24-30.
-
(1997)
Cerebrovasc Dis.
, vol.7
, pp. 24-30
-
-
Wahlgren, N.G.1
-
22
-
-
0028636535
-
Neurotoxicity of NMDA receptor antagonists: An overview
-
Olney JW. Neurotoxicity of NMDA receptor antagonists: an overview. Psychopharmacol Bull. 1994;30:533-540.
-
(1994)
Psychopharmacol Bull.
, vol.30
, pp. 533-540
-
-
Olney, J.W.1
-
23
-
-
0028925907
-
Why do all drugs work in animals but none in stroke patients? 2: Neuroprotective therapy
-
Grotta J. Why do all drugs work in animals but none in stroke patients? 2: neuroprotective therapy. J Intern Med. 1995;237:89-94.
-
(1995)
J Intern Med.
, vol.237
, pp. 89-94
-
-
Grotta, J.1
-
24
-
-
0027982679
-
Viability thresholds and the penumbra of focal ischemia
-
Hossman KA. Viability thresholds and the penumbra of focal ischemia. Ann Neurol. 1994;36:557-565.
-
(1994)
Ann Neurol.
, vol.36
, pp. 557-565
-
-
Hossman, K.A.1
-
25
-
-
0032472253
-
Focal ischemia enhances the adverse effect potential of N-methyl-D-aspartate receptor antagonists in rats
-
Loscher W, Wlaz P, Szabo L. Focal ischemia enhances the adverse effect potential of N-methyl-D-aspartate receptor antagonists in rats. Neurosci Lett. 1998;240:33-36.
-
(1998)
Neurosci Lett.
, vol.240
, pp. 33-36
-
-
Loscher, W.1
Wlaz, P.2
Szabo, L.3
-
26
-
-
0000290142
-
The current status of neuronal protective therapy: Why have all neuronal protective drugs worked in animals but none so far in stroke patients?
-
Grotta J. The current status of neuronal protective therapy: why have all neuronal protective drugs worked in animals but none so far in stroke patients? Cerebrovasc Dis. 1994;4:115-120.
-
(1994)
Cerebrovasc Dis.
, vol.4
, pp. 115-120
-
-
Grotta, J.1
-
27
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke
-
The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl Med. 1995;333:1581-1587.
-
(1995)
N Engl Med.
, vol.333
, pp. 1581-1587
-
-
-
28
-
-
0000111052
-
Defibrinogenation with Viprinex™ (ANCROD) for the treatment of acute ischemic stroke
-
Abstract
-
Sherman DG, for the STAT Writers Group. Defibrinogenation with Viprinex™ (ANCROD) for the treatment of acute ischemic stroke. Stroke. 1999;30:234. Abstract.
-
(1999)
Stroke
, vol.30
, pp. 234
-
-
Sherman, D.G.1
-
29
-
-
0032776135
-
Acute stroke therapy at the millennium: Consummating the marriage between the laboratory and bedside: The Feinberg Lecture
-
Grotta JC. Acute stroke therapy at the millennium: consummating the marriage between the laboratory and bedside: the Feinberg Lecture. Stroke. 1999;30:1722-1728.
-
(1999)
Stroke
, vol.30
, pp. 1722-1728
-
-
Grotta, J.C.1
-
30
-
-
0032984867
-
Which targets are relevant for therapy of acute ischemic stroke?
-
Heiss WD, Thiel A, Grond R. Which targets are relevant for therapy of acute ischemic stroke? Stroke. 1999;30:1486-1489.
-
(1999)
Stroke
, vol.30
, pp. 1486-1489
-
-
Heiss, W.D.1
Thiel, A.2
Grond, R.3
|