-
1
-
-
0031459452
-
Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
-
Coller BS. Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics. J Clin Invest. 1997;100(suppl 11):S57-S60.
-
(1997)
J Clin Invest.
, vol.100
, Issue.11 SUPPL.
-
-
Coller, B.S.1
-
2
-
-
0032518555
-
Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions
-
Goto S, Ikeda Y, Saldivar E, Ruggeri ZM. Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. J Clin Invest. 1998;101:479-486.
-
(1998)
J Clin Invest.
, vol.101
, pp. 479-486
-
-
Goto, S.1
Ikeda, Y.2
Saldivar, E.3
Ruggeri, Z.M.4
-
3
-
-
0032523064
-
Integrin signaling: The platelet paradigm
-
Shattil SJ, Kashiwagi H, Pampori N. Integrin signaling: the platelet paradigm. Blood. 1998;91:2645-2657.
-
(1998)
Blood
, vol.91
, pp. 2645-2657
-
-
Shattil, S.J.1
Kashiwagi, H.2
Pampori, N.3
-
4
-
-
0028117857
-
Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty
-
Tcheng JE, Ellis SG, George BS, Kereiakes DJ, Kleiman NS, Talley JD, Wang AL, Weisman HF, Califf RM, Topol EJ. Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty. Circulation. 1994;90: 1757-1764.
-
(1994)
Circulation
, vol.90
, pp. 1757-1764
-
-
Tcheng, J.E.1
Ellis, S.G.2
George, B.S.3
Kereiakes, D.J.4
Kleiman, N.S.5
Talley, J.D.6
Wang, A.L.7
Weisman, H.F.8
Califf, R.M.9
Topol, E.J.10
-
5
-
-
0032485876
-
Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade
-
Mascelli MA, Lance ET, Damaraju L, Wagner CL, Weisman HF, Jordan RE. Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade. Circulation. 1998;97: 1680-1688.
-
(1998)
Circulation
, vol.97
, pp. 1680-1688
-
-
Mascelli, M.A.1
Lance, E.T.2
Damaraju, L.3
Wagner, C.L.4
Weisman, H.F.5
Jordan, R.E.6
-
6
-
-
2242477091
-
Use of monoclonal antibody directed against the platelet glycoprotein IIb-IIIa receptor in high-risk coronary angioplasty
-
The EPIC Investigators. Use of monoclonal antibody directed against the platelet glycoprotein IIb-IIIa receptor in high-risk coronary angioplasty. N Engl J Med. 1994;330:956-961.
-
(1994)
N Engl J Med.
, vol.330
, pp. 956-961
-
-
-
7
-
-
1842369101
-
Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
-
The EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med. 1997;336:1689-1696.
-
(1997)
N Engl J Med.
, vol.336
, pp. 1689-1696
-
-
-
8
-
-
8544284052
-
3 blockade with percutaneous intervention
-
3 blockade with percutaneous intervention. JAMA. 1997;278:479-484.
-
(1997)
JAMA
, vol.278
, pp. 479-484
-
-
Topol, E.1
Ferguson, J.2
Weisman, H.3
Tcheng, J.4
Ellis, S.5
Kleimen, N.6
Ivanhoe, R.7
Wang, A.8
Miller, D.9
Anderson, K.10
Califf, R.11
-
9
-
-
0030918995
-
Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study
-
The Capture investigators. Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE study. Lancet. 1997;349:1429-1435.
-
(1997)
Lancet
, vol.349
, pp. 1429-1435
-
-
-
10
-
-
0032508297
-
Randomized placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein IIb/IIIa blockade
-
The Epistent Investigators. Randomized placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein IIb/IIIa blockade. Lancet. 1998;352:87-92.
-
(1998)
Lancet
, vol.352
, pp. 87-92
-
-
-
11
-
-
9244251971
-
A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents
-
Schomig A, Neumann F-J, Kastrati A, Schuhlen H, Blasini R, Hadamitzky M, Walter H, Zitzmann-Roth E-M, Richardt G, Alt E, Schmitt C, Ulm K. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med. 1996;334:1084-1089.
-
(1996)
N Engl J Med.
, vol.334
, pp. 1084-1089
-
-
Schomig, A.1
Neumann, F.-J.2
Kastrati, A.3
Schuhlen, H.4
Blasini, R.5
Hadamitzky, M.6
Walter, H.7
Zitzmann-Roth, E.-M.8
Richardt, G.9
Alt, E.10
Schmitt, C.11
Ulm, K.12
-
12
-
-
0030998690
-
Restoration of coronary flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: Observations in animals and humans
-
Gold HK, Garabedian HD, Dinsmore RE, Guerrero LJ, Cigarroa JE, Palacios IF, Leinbach RC. Restoration of coronary flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: observations in animals and humans. Circulation. 1997;95:1755-1759.
-
(1997)
Circulation
, vol.95
, pp. 1755-1759
-
-
Gold, H.K.1
Garabedian, H.D.2
Dinsmore, R.E.3
Guerrero, L.J.4
Cigarroa, J.E.5
Palacios, I.F.6
Leinbach, R.C.7
-
13
-
-
0030919511
-
Randomized placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
-
The IMPACT-II investigators. Randomized placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet. 1997;349:1422-1428.
-
(1997)
Lancet
, vol.349
, pp. 1422-1428
-
-
-
14
-
-
0032560628
-
International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina
-
The PARAGON investigators. International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina. Circulation. 1998;97:2386-2395.
-
(1998)
Circulation
, vol.97
, pp. 2386-2395
-
-
-
15
-
-
0343376106
-
Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
-
The RESTORE investigators. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation. 1997;96:1445-1453.
-
(1997)
Circulation
, vol.96
, pp. 1445-1453
-
-
-
16
-
-
0032578441
-
Pharmacodynamic efficacy, clinical safety, and outcomes after prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral xemilofiban
-
Kereiakes DJ, Kleiman NS, Ferguson JJ, Masud ARZ, Boderick TM, Abbottsmith CW, Runyan JP, Anderson LC, Anders RJ, Dreiling RJ, Hantsbarger GL, Bryzinski B, Topol EJ. Pharmacodynamic efficacy, clinical safety, and outcomes after prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral xemilofiban. Circulation. 1998; 98:1268-1278.
-
(1998)
Circulation
, vol.98
, pp. 1268-1278
-
-
Kereiakes, D.J.1
Kleiman, N.S.2
Ferguson, J.J.3
Masud, A.R.Z.4
Boderick, T.M.5
Abbottsmith, C.W.6
Runyan, J.P.7
Anderson, L.C.8
Anders, R.J.9
Dreiling, R.J.10
Hantsbarger, G.L.11
Bryzinski, B.12
Topol, E.J.13
-
17
-
-
0031856930
-
Oral antiplatelet efficacy and specificity of a novel nonpeptide platelet GP IIb/IIIa receptor antagonist, DMP 802
-
Mousa SA, Olson RE, Bozarth JM, Lorelli W, Forsythe MS, Racanelli A, Gibbs S, Schlingman K, Bozarth T, Kapil R, Wityak J, Sielecki TM, Wexler RR, Thoolen MJ, Slee A, Reilly TM, Anderson PS, Friedman PA. Oral antiplatelet efficacy and specificity of a novel nonpeptide platelet GP IIb/IIIa receptor antagonist, DMP 802. J Cardiovasc Pharmacol. 1998;32:169-176.
-
(1998)
J Cardiovasc Pharmacol.
, vol.32
, pp. 169-176
-
-
Mousa, S.A.1
Olson, R.E.2
Bozarth, J.M.3
Lorelli, W.4
Forsythe, M.S.5
Racanelli, A.6
Gibbs, S.7
Schlingman, K.8
Bozarth, T.9
Kapil, R.10
Wityak, J.11
Sielecki, T.M.12
Wexler, R.R.13
Thoolen, M.J.14
Slee, A.15
Reilly, T.M.16
Anderson, P.S.17
Friedman, P.A.18
-
18
-
-
0031726464
-
SR 121787, a new orally active fibrinogen receptor antagonist
-
Savi P, Badore A, Lale A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM. SR 121787, a new orally active fibrinogen receptor antagonist. Thromb Haemost. 1998;80:469-476.
-
(1998)
Thromb Haemost.
, vol.80
, pp. 469-476
-
-
Savi, P.1
Badore, A.2
Lale, A.3
Bordes, M.F.4
Bornia, J.5
Labouret, C.6
Bernat, A.7
De Cointet, P.8
Hoffmann, P.9
Maffrand, J.P.10
Herbert, J.M.11
-
19
-
-
0032552978
-
Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency: Implications for assay methodology and comparison of different antagonists
-
Storey RF, Wilcox RG, Heptinstall S. Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency: implications for assay methodology and comparison of different antagonists. Circulation. 1998;98:1616-1621.
-
(1998)
Circulation
, vol.98
, pp. 1616-1621
-
-
Storey, R.F.1
Wilcox, R.G.2
Heptinstall, S.3
-
21
-
-
0029744354
-
3 in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site (LIBS) recognized by monoclonal antibody AP-6
-
3 in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site (LIBS) recognized by monoclonal antibody AP-6. Blood. 1996;88:887-899.
-
(1996)
Blood
, vol.88
, pp. 887-899
-
-
Nurden, P.1
Humbert, M.2
Piotrowicz, R.S.3
Bihour, C.4
Poujol, C.5
Nurden, A.T.6
Kunicki, T.J.7
-
23
-
-
0033545294
-
RGD peptides induce apoptosis by direct caspase-3 activation
-
Buckley CD, Pilling D, Henriquez NV, Parsonage G, Threlfall K, Scheel-Toellner D, Simmons DL, Akbar AN, Lord JM, Salmon M. RGD peptides induce apoptosis by direct caspase-3 activation. Nature. 1999;397:534-539.
-
(1999)
Nature
, vol.397
, pp. 534-539
-
-
Buckley, C.D.1
Pilling, D.2
Henriquez, N.V.3
Parsonage, G.4
Threlfall, K.5
Scheel-Toellner, D.6
Simmons, D.L.7
Akbar, A.N.8
Lord, J.M.9
Salmon, M.10
-
24
-
-
0027267270
-
Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA
-
Tschoepe D, Schultheiss HP, Kolarov P, Schwippert B, Dannehl K, Volksw D, Nieuwenhuis HK, Kehrel B, Strauer B, Gries FA. Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA. Circulation. 1993;88:37-42.
-
(1993)
Circulation
, vol.88
, pp. 37-42
-
-
Tschoepe, D.1
Schultheiss, H.P.2
Kolarov, P.3
Schwippert, B.4
Dannehl, K.5
Volksw, D.6
Nieuwenhuis, H.K.7
Kehrel, B.8
Strauer, B.9
Gries, F.A.10
-
25
-
-
0026488342
-
Activation of platelets in blood perfusing angioplasty-damaged coronary arteries: Flow cytometric detection
-
Scharf RE, Tomer A, Marzec UM, Teirstein PS, Ruggeri ZR, Harker LA. Activation of platelets in blood perfusing angioplasty-damaged coronary arteries: flow cytometric detection. Arterioscler Thromb. 1992;12:1475-1487.
-
(1992)
Arterioscler Thromb.
, vol.12
, pp. 1475-1487
-
-
Scharf, R.E.1
Tomer, A.2
Marzec, U.M.3
Teirstein, P.S.4
Ruggeri, Z.R.5
Harker, L.A.6
-
26
-
-
0033043709
-
Expression of markers of platelet activation and the interpatient variation in response to abciximab
-
Bihour C, Durrieu-Jaïs C, Macchi L, Poujol C, Coste P, Besse P, Nurden P, Nurden AT. Expression of markers of platelet activation and the interpatient variation in response to abciximab. Arterioscler Thromb Vasc Biol. 1999;19:212-219.
-
(1999)
Arterioscler Thromb Vasc Biol.
, vol.19
, pp. 212-219
-
-
Bihour, C.1
Durrieu-Jaïs, C.2
Macchi, L.3
Poujol, C.4
Coste, P.5
Besse, P.6
Nurden, P.7
Nurden, A.T.8
-
27
-
-
0032212143
-
3) inhibitors
-
3) inhibitors. Blood. 1998;92:3240-3249.
-
(1998)
Blood
, vol.92
, pp. 3240-3249
-
-
Peter, K.1
Schwarz, M.2
Ylänne, J.3
Kohler, B.4
Moser, M.5
Nordt, T.6
Salbach, P.7
Kübler, W.8
Bode, W.9
-
28
-
-
0027528320
-
Arg-Gly-Asp-dependent occupancy of GP IIb/IIIa by applaggin: Evidence for internalization and cycling of a platelet integrin
-
Wencel-Drake JD, Frelinger AL III, Dieter MG, Lam SC-T. Arg-Gly-Asp-dependent occupancy of GP IIb/IIIa by applaggin: evidence for internalization and cycling of a platelet integrin. Blood. 1995;81: 62-69.
-
(1995)
Blood
, vol.81
, pp. 62-69
-
-
Wencel-Drake, J.D.1
Frelinger A.L. III2
Dieter, M.G.3
Lam, S.C.-T.4
-
29
-
-
0028807209
-
Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus chimeric 7E3 Fab: Implications for inhibition of the internal pool of GP IIb-IIIa receptors
-
Kleimann NS, Raizner AE, Jordan R, Wang AL, Norton D, Mace KF, Joshi A, Coller BS, Weisman HF. Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus chimeric 7E3 Fab: implications for inhibition of the internal pool of GP IIb-IIIa receptors. J Am Coll Cardiol. 1995;26:1665-1671.
-
(1995)
J am Coll Cardiol.
, vol.26
, pp. 1665-1671
-
-
Kleimann, N.S.1
Raizner, A.E.2
Jordan, R.3
Wang, A.L.4
Norton, D.5
Mace, K.F.6
Joshi, A.7
Coller, B.S.8
Weisman, H.F.9
-
30
-
-
0030830577
-
Bidirectional trafficking of membrane glycoproteins following platelet activation in suspension
-
Nurden P. Bidirectional trafficking of membrane glycoproteins following platelet activation in suspension. Thromb Haemost. 1997;78: 1305-1315.
-
(1997)
Thromb Haemost.
, vol.78
, pp. 1305-1315
-
-
Nurden, P.1
-
31
-
-
0342717357
-
Labeling of the internal pool of GP IIb-IIIa in platelets of patients receiving c7E3 Fab fragments (abciximab, ReoPro): Flow and endocytic mechanisms contribute to the transport
-
Nurden P, Poujol C, Durrieu-Jais C, Winckler J, Combrié R, Macchi L, Bihour C, Wagner C, Jordan R, Nurden AT. Labeling of the internal pool of GP IIb-IIIa in platelets of patients receiving c7E3 Fab fragments (abciximab, ReoPro): flow and endocytic mechanisms contribute to the transport. Blood. 1999;93:212-219.
-
(1999)
Blood
, vol.93
, pp. 212-219
-
-
Nurden, P.1
Poujol, C.2
Durrieu-Jais, C.3
Winckler, J.4
Combrié, R.5
Macchi, L.6
Bihour, C.7
Wagner, C.8
Jordan, R.9
Nurden, A.T.10
-
32
-
-
0021602988
-
Molecular defects in interaction of platelets with the vessel wall
-
George JN, Nurden AT, Phillips DR. Molecular defects in interaction of platelets with the vessel wall. N Engl J Med. 1984;311:1094-1098.
-
(1984)
N Engl J Med.
, vol.311
, pp. 1094-1098
-
-
George, J.N.1
Nurden, A.T.2
Phillips, D.R.3
-
33
-
-
0031543296
-
'Rescue' utilization of abciximab for the dissolution of coronary thrombus developing as a complication of coronary angioplasty
-
Muhlestein JB, Karagounis LA, Treehan S, Anderson JL. 'Rescue' utilization of abciximab for the dissolution of coronary thrombus developing as a complication of coronary angioplasty. J Am Coll Cardiol. 1997:30:1729-1734.
-
(1997)
J am Coll Cardiol.
, vol.30
, pp. 1729-1734
-
-
Muhlestein, J.B.1
Karagounis, L.A.2
Treehan, S.3
Anderson, J.L.4
-
34
-
-
0032147003
-
Increased platelet responsiveness following coronary stenting: Heparin as a possible aetiological factor in stent thrombosis
-
Knight CJ, Panesar M, Wilson DJ, Patrineli A, Chronos N, Wright C, Clarke D, Patel D, Fox K, Goodall AH. Increased platelet responsiveness following coronary stenting: heparin as a possible aetiological factor in stent thrombosis. Eur Heart J. 1998;19:1239-1248.
-
(1998)
Eur Heart J.
, vol.19
, pp. 1239-1248
-
-
Knight, C.J.1
Panesar, M.2
Wilson, D.J.3
Patrineli, A.4
Chronos, N.5
Wright, C.6
Clarke, D.7
Patel, D.8
Fox, K.9
Goodall, A.H.10
-
35
-
-
0033537494
-
Rapid platelet-function assay: An automated and quantitative cartridge-based method
-
Smith JW, Steinhubl SR, Lincoff AM, Coleman JC, Lee TT, Hillman RS, Coller BS. Rapid platelet-function assay: an automated and quantitative cartridge-based method. Circulation. 1999;99:620-625.
-
(1999)
Circulation
, vol.99
, pp. 620-625
-
-
Smith, J.W.1
Steinhubl, S.R.2
Lincoff, A.M.3
Coleman, J.C.4
Lee, T.T.5
Hillman, R.S.6
Coller, B.S.7
-
36
-
-
0033565442
-
Inhibition of platelet aggregation by abciximab but not by aspirin can be detected by a new point-of-care test the HemoSTATUS
-
Coiffic A, Cazes E, Janvier G, Lanza F, Nurden A, Nurden P. Inhibition of platelet aggregation by abciximab but not by aspirin can be detected by a new point-of-care test the HemoSTATUS. Thromb Res. 1999;95:83-91.
-
(1999)
Thromb Res.
, vol.95
, pp. 83-91
-
-
Coiffic, A.1
Cazes, E.2
Janvier, G.3
Lanza, F.4
Nurden, A.5
Nurden, P.6
-
38
-
-
0030934389
-
7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1
-
Simon DI, Xu H, Ortlepp S, Rogers C, Rao NK. 7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1. Arterioscler Thromb Vasc Biol. 1997;17:528-535.
-
(1997)
Arterioscler Thromb Vasc Biol.
, vol.17
, pp. 528-535
-
-
Simon, D.I.1
Xu, H.2
Ortlepp, S.3
Rogers, C.4
Rao, N.K.5
-
39
-
-
0029914728
-
Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody: Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and 'clinical restenosis.'
-
Reverter JC, Béguin S, Kessels H, Kumar R, Hemker HC, Coller BS. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody: potential implications for the effect of c7E3 Fab treatment on acute thrombosis and 'clinical restenosis.' J Clin Invest. 1996;98:863-874.
-
(1996)
J Clin Invest.
, vol.98
, pp. 863-874
-
-
Reverter, J.C.1
Béguin, S.2
Kessels, H.3
Kumar, R.4
Hemker, H.C.5
Coller, B.S.6
-
40
-
-
0030870212
-
3 binds prothrombin and influences its activation
-
3 binds prothrombin and influences its activation. J Biol Chem. 1997;272:183-188.
-
(1997)
J Biol Chem.
, vol.272
, pp. 183-188
-
-
Byzova, T.V.1
Plow, E.F.2
-
41
-
-
0032520709
-
Inhibition of platelet-mediated clot retraction by integrin antagonists
-
Hantgen RR, Mousa SA. Inhibition of platelet-mediated clot retraction by integrin antagonists. Thromb Res. 1998;89:271-279.
-
(1998)
Thromb Res.
, vol.89
, pp. 271-279
-
-
Hantgen, R.R.1
Mousa, S.A.2
|