Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat

Journal of Cerebral Blood Flow and Metabolism

Volumn 16, Issue 4, 1996, Pages 542-547

  Kawamata, Takakazu ^a   Alexis, Nancy E ^b   Dietrich, W Dalton ^b   Finklestein, Seth P ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Basic fibroblast growth factor; Behavior; Cerebral infarction; Recovery

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; CELL SURVIVAL; HYPOTHESIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION;

EID: 0029991601     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199607000-00003     Document Type: Article

References (19)

1. Alexis NE, Dietrich WD, Green EJ, Prado R, Watson BD (1995) Nonocclusive common carotid artery thrombosis in the rat results in reversible sensorimotor and cognitive behavioral deficits. Stroke 26:2,338-2,346
2. Baird A (1994) Fibroblast growth factors: Activities and significance of nonneurotrophin neurotrophic growth factors. Curr Opinion Neurobiol 4:78-86
3. Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination. Stroke 17:472-476
4. Berlove DJ, Finklestein SP (1993) Growth Factors and Brain Injury. In: Growth Factors. Peptides and Receptors. (Moody TW, eds.), New York, Plenum Press, pp 137-143
5. DeRyck M, van Reempts J, Duytschaever H, van Deuren B, Clincke G (1992) Neocortical localization of tactile/proprioceptive limb placing reactions in the rat. Brain Res 573:44-60
6. Finklestein SP (1995) Growth Factors in Stroke. In: Brain Ischemia: Basic Concepts and Clinical Relevance. (Caplan LR, eds.), London, Springer-Verlag, pp 37-41
7. Fisher M, Meadows M-E, Do T, Weise J, Trubetskoy V, Charette M, Finklestein SP (1995) Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal ischemia in rats. J Cereb Blood Flow Metab 15:953-959
8. Goldstein LG, Davis JN (1990) Restorative neurology: Drugs and recovery following stroke. Stroke 21:1,636-1,640
9. Jones TA, Schallert T (1994) Use-dependent growth of pyramidal neurons after neocortical damage. J Neurosci 14:2, 140-2,152
10. Koketsu N, Berlove DJ, Moskowitz MA, Kowall NW, Caday CG, Finkelstein SP (1994) Pretreatment with intraventricular basic fibroblast growth factor (bFGF) decreases infarct size following focal cerebral ischemia in rats. Ann Neural 35: 451-457
11. Markgraf CG, Green EJ, Hurwitz BE, Morikawa E, Dietrich WD, McCabe PM, Ginsberg MD, Schneiderman N (1992) Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats. Brain Res 575:238-246
12. Paxinos G, Watson C (1986) The Rat Brain in Stereotaxic Coordinates. San Diego, Academic Press.
13. Stroemer RP, Kent TA, Hulsebosch CE (1995) Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke 26:2,135-2,144
14. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR (1990) A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab 10:290-293
15. Tamura A, Graham DI, McCuIloch J, Teasdale GM (1981) Focal cerebral ischemia in the rat: 1. Description of technique and early neuropathológical consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1:53-60
16. Weiller C, Chollet F, Fristen KJ, Wise RJ, Frackowiak RS (1992) Functional reorganization of the brain in recovery from striatocapsular infarction in man. Ann Neural 31:463-472
17. Yamada K, Kinoshita A, Kohmura E, Sakaguchi T, Taguchi J, Kataoka K, Hayakawa T (1991) Basic fibroblast growth factor prevents thalamic degeneration after cortical infarction. J Cereb Blood Flow Metab 11:472-478
18. Yamaguchi T, Suzuki M, Yamamoto M (1995) YM796, a novel muscarinic agonist, improves the impairment of learning behavior in a rat model of chronic focal cerebral ischemia. Brain Res 669:107-114
19. Yamamoto M, Tamura A, Kirino T, Shimizu-Sasamata M, Sano K (1991) Effects of thyrotropin-releasing hormone on behavioral disturbances in middle cerebral artery-occluded rats. Eur J Pharmacol 197:117-123