메뉴 건너뛰기




Volumn 37, Issue , 1997, Pages 239-267

Pharmacology of neurotrophic factors

Author keywords

nerve growth factor; neurodegeneration; neuropathy; trk receptors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; GLIAL CELL DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; SOMATOMEDIN C; UNCLASSIFIED DRUG;

EID: 0030928225     PISSN: 00664251     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.37.1.239     Document Type: Review
Times cited : (163)

References (229)
  • 1
    • 0004539754 scopus 로고
    • NGF: An uncharted route
    • ed. FG Wooten, JP Swazey, GAdelman. Cambridge, MA: MIT Press
    • Levi-Montalcini R. 1975. NGF: An uncharted route. In The Neurosciences: Paths of Discovery, ed. FG Wooten, JP Swazey, GAdelman. Cambridge, MA: MIT Press
    • (1975) The Neurosciences: Paths of Discovery
    • Levi-Montalcini, R.1
  • 2
    • 0029892470 scopus 로고    scopus 로고
    • The physiology of neurotrophins
    • Barde YA. 1996. The physiology of neurotrophins. Annu. Rev. Neurosci. 19:289-317
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 289-317
    • Barde, Y.A.1
  • 3
    • 0026718849 scopus 로고
    • Functional and evolution in the NGF family and its receptors
    • Ebendal T. 1992. Functional and evolution in the NGF family and its receptors. J. Neurosci. Res. 32:461-70
    • (1992) J. Neurosci. Res. , vol.32 , pp. 461-470
    • Ebendal, T.1
  • 4
    • 0026730310 scopus 로고
    • Neurotrophic receptors: A window into neuronal differentiation
    • Chao MV. 1992. Neurotrophic receptors: a window into neuronal differentiation. Neuron 9:583-93
    • (1992) Neuron , vol.9 , pp. 583-593
    • Chao, M.V.1
  • 5
    • 0028931552 scopus 로고
    • Neurotrophic factors and their receptors
    • Barbacid M. 1995. Neurotrophic factors and their receptors. Curr: Opin. Cell Biol. 7:148-55
    • (1995) Curr: Opin. Cell Biol. , vol.7 , pp. 148-155
    • Barbacid, M.1
  • 6
  • 7
    • 0027324122 scopus 로고
    • Induction of apoptosis by the low-affinity NGF receptor
    • Rabizadeh S, Oh J, Zhong L-T, Yang J, Bitler CM, et al. 1993. Induction of apoptosis by the low-affinity NGF receptor. Science 261:345-48
    • (1993) Science , vol.261 , pp. 345-348
    • Rabizadeh, S.1    Oh, J.2    Zhong, L.-T.3    Yang, J.4    Bitler, C.M.5
  • 8
    • 0021176141 scopus 로고
    • Use of central neuronal cultures for the detection of neuronotrophic agents
    • Barbin G, Selak I, Manthorpe M, Varon S. 1984. Use of central neuronal cultures for the detection of neuronotrophic agents. Neuroscience 12:33-43
    • (1984) Neuroscience , vol.12 , pp. 33-43
    • Barbin, G.1    Selak, I.2    Manthorpe, M.3    Varon, S.4
  • 9
    • 0024409029 scopus 로고
    • Purification, cloning, and expression of ciliary neurotrophic factor (CNTF)
    • Lin L-FH, Mismer D, Lile JD, Armes LG, Butler ET III, et al. 1989. Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). Science 246:1023-25
    • (1989) Science , vol.246 , pp. 1023-1025
    • Lin, L.-F.H.1    Mismer, D.2    Lile, J.D.3    Armes, L.G.4    Butler E.T. III5
  • 10
    • 0027964830 scopus 로고
    • Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology
    • Patterson PH. 1994. Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology. Proc. Natl. Acad. Sci. USA 91:7833-35
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7833-7835
    • Patterson, P.H.1
  • 11
    • 0028905072 scopus 로고
    • Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signalling complex
    • Pennica D, Shaw KJ, Swanson TA, Moore MW, Shelton DL, et al. 1995. Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signalling complex. J. Biol. Chem. 270:10915-22
    • (1995) J. Biol. Chem. , vol.270 , pp. 10915-10922
    • Pennica, D.1    Shaw, K.J.2    Swanson, T.A.3    Moore, M.W.4    Shelton, D.L.5
  • 13
    • 0027403260 scopus 로고
    • The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development
    • Ip NY, McClain J, Barrezueta NX, Aldrich TH. Pan L, et al. 1993. The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10:89-102
    • (1993) Neuron , vol.10 , pp. 89-102
    • Ip, N.Y.1    McClain, J.2    Barrezueta, N.X.3    Aldrich, T.H.4    Pan, L.5
  • 14
    • 0020333865 scopus 로고
    • Insulin and somatomedin MSA promote nerve growth factor-independent neunte formation by cultured chick dorsal root ganglionic sensory neurons
    • Bothwell M. 1982. Insulin and somatomedin MSA promote nerve growth factor-independent neunte formation by cultured chick dorsal root ganglionic sensory neurons. J. Neurosci. Res. 8:225-31
    • (1982) J. Neurosci. Res. , vol.8 , pp. 225-231
    • Bothwell, M.1
  • 15
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin LFH, Doherty DH, Lile JD, Bektesh S, Collins F. 1993. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-34
    • (1993) Science , vol.260 , pp. 1130-1134
    • Lin, L.F.H.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 16
    • 13344277993 scopus 로고    scopus 로고
    • Functional recovery in Parkinsonian monkeys treated with GDNF
    • Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, et al. 1996. Functional recovery in Parkinsonian monkeys treated with GDNF. Nature 380:252
    • (1996) Nature , vol.380 , pp. 252
    • Gash, D.M.1    Zhang, Z.2    Ovadia, A.3    Cass, W.A.4    Yi, A.5
  • 17
    • 0028791689 scopus 로고
    • Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats
    • Fisher M, Meadows M-E, Do T, Weise J, Trubetskoy V, et al. 1995. Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats. J. Cerebral Blood Flow Metab. 15:953-59
    • (1995) J. Cerebral Blood Flow Metab. , vol.15 , pp. 953-959
    • Fisher, M.1    Meadows, M.-E.2    Do, T.3    Weise, J.4    Trubetskoy, V.5
  • 18
    • 0024264753 scopus 로고
    • Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on CNS neurons
    • Morrison RS, Keating RF, Moskal JR. 1988. Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on CNS neurons. J. Neurosci. Res. 21:71-79
    • (1988) J. Neurosci. Res. , vol.21 , pp. 71-79
    • Morrison, R.S.1    Keating, R.F.2    Moskal, J.R.3
  • 19
    • 0027214522 scopus 로고
    • Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture
    • Alexi T, Hefti F. 1993. Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture. Neuroscience 55:803-8
    • (1993) Neuroscience , vol.55 , pp. 803-808
    • Alexi, T.1    Hefti, F.2
  • 20
    • 0028989595 scopus 로고
    • Cloning of AL-1, a ligand for an eph-related tyrosine kinase receptor involved in axon bundle formation
    • Winslow JW, Moran P, Valverde J, Shih A, Yuan JQ, et al. 1995. Cloning of AL-1, a ligand for an eph-related tyrosine kinase receptor involved in axon bundle formation. Neuron 14:973-81
    • (1995) Neuron , vol.14 , pp. 973-981
    • Winslow, J.W.1    Moran, P.2    Valverde, J.3    Shih, A.4    Yuan, J.Q.5
  • 21
    • 0029082312 scopus 로고
    • In vitro guidance of retinal ganglion cell axons by RAGS, a 25Kda tectal protein related to ligands for Eph receptor tyrosine kinases
    • Drescher U, Kremoser C, Handwerker C, Loschinger J, Noda M, Bonhoeffer F. 1995. In vitro guidance of retinal ganglion cell axons by RAGS, a 25Kda tectal protein related to ligands for Eph receptor tyrosine kinases. Cell 82:359-70
    • (1995) Cell , vol.82 , pp. 359-370
    • Drescher, U.1    Kremoser, C.2    Handwerker, C.3    Loschinger, J.4    Noda, M.5    Bonhoeffer, F.6
  • 22
    • 0029086140 scopus 로고
    • Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
    • Cheng H-J, Nakamoto M, Bergemann A, Flanagan JC. 1995. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82:371
    • (1995) Cell , vol.82 , pp. 371
    • Cheng, H.-J.1    Nakamoto, M.2    Bergemann, A.3    Flanagan, J.C.4
  • 23
    • 0030026594 scopus 로고    scopus 로고
    • Function of the Eph-related kinase rtkl in patterning of the zebrafish forebrain
    • Xu Q, Alldus G, Macdonald R, Wilkinson DG, Holder N. 1996. Function of the Eph-related kinase rtkl in patterning of the zebrafish forebrain. Nature 381:319
    • (1996) Nature , vol.381 , pp. 319
    • Xu, Q.1    Alldus, G.2    Macdonald, R.3    Wilkinson, D.G.4    Holder, N.5
  • 24
    • 0029087510 scopus 로고
    • Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse-Tyro 3
    • Godowski PJ, Mark MR, Chen J, Sadick MD, Raab H, Hammonds RG. 1995. Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse-Tyro 3. Cell 82:355-58
    • (1995) Cell , vol.82 , pp. 355-358
    • Godowski, P.J.1    Mark, M.R.2    Chen, J.3    Sadick, M.D.4    Raab, H.5    Hammonds, R.G.6
  • 25
    • 0026659262 scopus 로고
    • Identification of heregulin, a specific activator of p185erbB2
    • Holmes WE, Slowkowski MX, Akita RW, Henzel WJ, Lee J, et al. 1992. Identification of heregulin, a specific activator of p185erbB2. Science 256:1205-08
    • (1992) Science , vol.256 , pp. 1205-1208
    • Holmes, W.E.1    Slowkowski, M.X.2    Akita, R.W.3    Henzel, W.J.4    Lee, J.5
  • 26
    • 0027526321 scopus 로고
    • ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family
    • Falls DL, Rosen KM, Corfas G, Lane WS, Fischbach GD. 1993. ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72:801-15
    • (1993) Cell , vol.72 , pp. 801-815
    • Falls, D.L.1    Rosen, K.M.2    Corfas, G.3    Lane, W.S.4    Fischbach, G.D.5
  • 27
    • 0027530106 scopus 로고
    • Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
    • Marchionni MA, Goodearl ADJ, Chen MS, Bermingham-McDonogh O, Kirk C, et al. 1993. Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system. Nature 362:312-16
    • (1993) Nature , vol.362 , pp. 312-316
    • Marchionni, M.A.1    Goodearl, A.D.J.2    Chen, M.S.3    Bermingham-McDonogh, O.4    Kirk, C.5
  • 28
    • 0026669893 scopus 로고
    • Characterization of bovine heparin-binding neurotrophic factor (HBNF): Assignment of disulfide bonds
    • Fabri L, Nice EC, Ward LD, Maruta H, Burgess AW, Simpson RJ. 1992. Characterization of bovine heparin-binding neurotrophic factor (HBNF): assignment of disulfide bonds. Biochem. Intl. 28:1-9
    • (1992) Biochem. Intl. , vol.28 , pp. 1-9
    • Fabri, L.1    Nice, E.C.2    Ward, L.D.3    Maruta, H.4    Burgess, A.W.5    Simpson, R.J.6
  • 29
    • 0028940896 scopus 로고
    • Differential expression of pleiotrophin and mid-kine in advanced neuroblastomas
    • Nakagawara A, Milbrandt J, Muramatsu T, Deuel T F, Zhao H, et al. 1995. Differential expression of pleiotrophin and mid-kine in advanced neuroblastomas. Cancer Res. 55:1792-97
    • (1995) Cancer Res. , vol.55 , pp. 1792-1797
    • Nakagawara, A.1    Milbrandt, J.2    Muramatsu, T.3    Deuel, T.F.4    Zhao, H.5
  • 30
    • 0025073281 scopus 로고
    • Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: Comparision between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo
    • Spranger M, Lindholm D, Bandtlow C, Heumann R, Gnahn H, et al. 1990. Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: comparision between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo. Eur. J. Neurosci. 2:69-76
    • (1990) Eur. J. Neurosci. , vol.2 , pp. 69-76
    • Spranger, M.1    Lindholm, D.2    Bandtlow, C.3    Heumann, R.4    Gnahn, H.5
  • 31
    • 0027232014 scopus 로고
    • Trophic effect of erythropoietin and other hemotopoietic factors on central cholinergic neurons in vitro and in vivo
    • Konishi Y, Chui DH, Hirose H, Kunishita T, Tabira T. 1993. Trophic effect of erythropoietin and other hemotopoietic factors on central cholinergic neurons in vitro and in vivo. Brain Res. 609:29-35
    • (1993) Brain Res. , vol.609 , pp. 29-35
    • Konishi, Y.1    Chui, D.H.2    Hirose, H.3    Kunishita, T.4    Tabira, T.5
  • 32
    • 0023497758 scopus 로고
    • The physiological function of nerve growth factor in the central nervous system: Comparison with the periphery
    • Thoenen H, Bandtlow C, Heumann R. 1987. The physiological function of nerve growth factor in the central nervous system: comparison with the periphery. Rev. Physiol. Biochem. Pharmacol. 109:145-178
    • (1987) Rev. Physiol. Biochem. Pharmacol. , vol.109 , pp. 145-178
    • Thoenen, H.1    Bandtlow, C.2    Heumann, R.3
  • 33
    • 0028238769 scopus 로고
    • Functions of neurotrophins during nervous system development: What the knockouts are teaching us
    • Snider WD. 1994. Functions of neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-38
    • (1994) Cell , vol.77 , pp. 627-638
    • Snider, W.D.1
  • 34
    • 0026442248 scopus 로고
    • Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development
    • Ernfors P, Merlio J-P, Persson H. 1992. Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development. Eur. J. Neurosci. 4:1140-58
    • (1992) Eur. J. Neurosci. , vol.4 , pp. 1140-1158
    • Ernfors, P.1    Merlio, J.-P.2    Persson, H.3
  • 35
    • 0026756421 scopus 로고
    • Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus
    • Collazo D, Takahashi H, McKay RDG. 1992. Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus. Neuron 9:643-56
    • (1992) Neuron , vol.9 , pp. 643-656
    • Collazo, D.1    Takahashi, H.2    McKay, R.D.G.3
  • 36
    • 0028806187 scopus 로고
    • Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo
    • Cohen-Cory S, Fraser SE. 1995. Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo. Nature 378:192
    • (1995) Nature , vol.378 , pp. 192
    • Cohen-Cory, S.1    Fraser, S.E.2
  • 37
    • 0029020311 scopus 로고
    • Neurotrophins promote maturation of developing neuormuscular synapses
    • Wang T, Xie KW, Lu B. 1995. Neurotrophins promote maturation of developing neuormuscular synapses. J. Neurosci. 15(7 pt 1):4796-805
    • (1995) J. Neurosci. , vol.15 , Issue.7 PART 1 , pp. 4796-4805
    • Wang, T.1    Xie, K.W.2    Lu, B.3
  • 38
    • 0028793476 scopus 로고
    • NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation
    • Riddle DR, Lo DC, Katz LC. 1995. NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation. Nature 378:189
    • (1995) Nature , vol.378 , pp. 189
    • Riddle, D.R.1    Lo, D.C.2    Katz, L.C.3
  • 39
    • 0027208231 scopus 로고
    • The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus
    • Castrén E, Pitkänen M, Sirviö J, Parsadanian A, Lindholm D, et al. 1993. The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. NeuroReport 4:895-98
    • (1993) NeuroReport , vol.4 , pp. 895-898
    • Castrén, E.1    Pitkänen, M.2    Sirviö, J.3    Parsadanian, A.4    Lindholm, D.5
  • 40
  • 41
  • 42
    • 0028788476 scopus 로고
    • Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth
    • DeChiara TM, Vejsada R, Poueymirou WT, Acheson A, Suri C, et al. 1995. Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83:313-22
    • (1995) Cell , vol.83 , pp. 313-322
    • DeChiara, T.M.1    Vejsada, R.2    Poueymirou, W.T.3    Acheson, A.4    Suri, C.5
  • 43
    • 0022486717 scopus 로고
    • Nerve growth factor (NGF) promotes survival of septal cholinergic neurons after fimbrial transactions
    • Hefti F. 1986. Nerve growth factor (NGF) promotes survival of septal cholinergic neurons after fimbrial transactions. J. Neurosci. 6:2155-62
    • (1986) J. Neurosci. , vol.6 , pp. 2155-2162
    • Hefti, F.1
  • 44
    • 0029878449 scopus 로고    scopus 로고
    • GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis
    • Beck KD, Irwin I, Valverde J, Brennan TJ, Langston JW, Hefti F. 1996. GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis. Neuron 16:665-73
    • (1996) Neuron , vol.16 , pp. 665-673
    • Beck, K.D.1    Irwin, I.2    Valverde, J.3    Brennan, T.J.4    Langston, J.W.5    Hefti, F.6
  • 45
    • 0027134807 scopus 로고
    • Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF and NT3
    • Sofroniew MV, Cooper JD, Svendsen CN, Crossman P, Ip NY, et al. 1993. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF and NT3. J. Neurosci. 13:5263-76
    • (1993) J. Neurosci. , vol.13 , pp. 5263-5276
    • Sofroniew, M.V.1    Cooper, J.D.2    Svendsen, C.N.3    Crossman, P.4    Ip, N.Y.5
  • 46
    • 0029939502 scopus 로고    scopus 로고
    • Regulated release and polarised localisation of brain-derived neurotrophic factor (BDNF) in hippocampal neurons
    • Goodman LJ, Valverde J, Lim F, Geschwind MD, Federoff HJ, et al. 1996. Regulated release and polarised localisation of brain-derived neurotrophic factor (BDNF) in hippocampal neurons. Mol. Cell. Neurosci. 7:222-38
    • (1996) Mol. Cell. Neurosci. , vol.7 , pp. 222-238
    • Goodman, L.J.1    Valverde, J.2    Lim, F.3    Geschwind, M.D.4    Federoff, H.J.5
  • 47
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen H. 1995. Neurotrophins and neuronal plasticity. Science 270:593-98
    • (1995) Science , vol.270 , pp. 593-598
    • Thoenen, H.1
  • 48
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mR-NAs
    • Patterson SL, Grover LM, Schwartzkroin PA, Bothwell M. 1992. Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mR-NAs. Neuron 9:1081-88
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.L.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 49
    • 0029987847 scopus 로고    scopus 로고
    • Unilateral LTP triggers bilateral increases in hippocampal neurotrophin and trk receptor mRNA expression in behaving rats: Evidence for interhemispheric communication
    • Bramham CR, Southard T, Sarvey JM, Herkenham M, Brady LS. 1996. Unilateral LTP triggers bilateral increases in hippocampal neurotrophin and trk receptor mRNA expression in behaving rats: evidence for interhemispheric communication. J. Comp. Neurol. 368:371-82
    • (1996) J. Comp. Neurol. , vol.368 , pp. 371-382
    • Bramham, C.R.1    Southard, T.2    Sarvey, J.M.3    Herkenham, M.4    Brady, L.S.5
  • 51
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival: Lessions from the nervous system
    • Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD. 1993. Programmed cell death and the control of cell survival: lessions from the nervous system. Science 262:695
    • (1993) Science , vol.262 , pp. 695
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 52
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp TE, Wyatt S, Paterson HF, Davies AM. 1993. The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73:295-307
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 53
    • 0027304383 scopus 로고
    • BCL-2 blocks glutamate toxicity in neural cell lines
    • Zhong L-T, Kane DJ, Bredesen DE. 1993. BCL-2 blocks glutamate toxicity in neural cell lines. Mol. Brain Res. 19:353-55
    • (1993) Mol. Brain Res. , vol.19 , pp. 353-355
    • Zhong, L.-T.1    Kane, D.J.2    Bredesen, D.E.3
  • 54
    • 0027717968 scopus 로고
    • Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
    • Kane DJ, Sarafian TA, Anton R, Hahn H, Butler Gralla E, et al. 1993. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262:1274
    • (1993) Science , vol.262 , pp. 1274
    • Kane, D.J.1    Sarafian, T.A.2    Anton, R.3    Hahn, H.4    Butler Gralla, E.5
  • 55
    • 0029972440 scopus 로고    scopus 로고
    • Cell cycle blockers mimosine, ciclopirox and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support
    • Farinelli SE, Greene LA. 1996. Cell cycle blockers mimosine, ciclopirox and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support. J. Neurosci. 16:1150-62
    • (1996) J. Neurosci. , vol.16 , pp. 1150-1162
    • Farinelli, S.E.1    Greene, L.A.2
  • 56
    • 0029670265 scopus 로고    scopus 로고
    • ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
    • Nicholson DW. 1996. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis. Nature Biotech. 14:297
    • (1996) Nature Biotech. , vol.14 , pp. 297
    • Nicholson, D.W.1
  • 57
    • 0029048295 scopus 로고
    • Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
    • Gwag BJ, Lobner D, Koh JY, Wie MB, Choi DW. 1995. Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro. Neuroscience 68:615-19
    • (1995) Neuroscience , vol.68 , pp. 615-619
    • Gwag, B.J.1    Lobner, D.2    Koh, J.Y.3    Wie, M.B.4    Choi, D.W.5
  • 58
    • 0029115971 scopus 로고
    • A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
    • Patil N, Cox DR, Bhat D, Faham M, Myers RM, Peterson AS. 1995. A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat. Genet. 11:126
    • (1995) Nat. Genet. , vol.11 , pp. 126
    • Patil, N.1    Cox, D.R.2    Bhat, D.3    Faham, M.4    Myers, R.M.5    Peterson, A.S.6
  • 59
    • 0023618973 scopus 로고
    • Motor neuron diseases and amyotrophic lateral sclerosis: Research progress
    • Rowland LP. 1987. Motor neuron diseases and amyotrophic lateral sclerosis: research progress. Trends Neurosci. 10:393-97
    • (1987) Trends Neurosci. , vol.10 , pp. 393-397
    • Rowland, L.P.1
  • 60
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, et al. 1993. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362:59-61
    • (1993) Nature , vol.362 , pp. 59-61
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5
  • 61
    • 0027965073 scopus 로고
    • Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity
    • Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu Z-S, et al. 1994. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc. Natl. Acad. Sci. USA 91:8292-96
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8292-8296
    • Borchelt, D.R.1    Lee, M.K.2    Slunt, H.S.3    Guarnieri, M.4    Xu, Z.-S.5
  • 62
    • 0029671220 scopus 로고    scopus 로고
    • Altered reactivity of superoxide dismutate in familial lateral sclerosis
    • Wiedau-Pazos M, Goto JJ, Rabizadeh S, Gralla EB, Roe JA, et al. 1996 Altered reactivity of superoxide dismutate in familial lateral sclerosis. Science 271:515
    • (1996) Science , vol.271 , pp. 515
    • Wiedau-Pazos, M.1    Goto, J.J.2    Rabizadeh, S.3    Gralla, E.B.4    Roe, J.A.5
  • 63
    • 0030034545 scopus 로고    scopus 로고
    • SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis
    • Rouleau GA, Clark AW, Rooke K, Pramatarova A, Krizus A, et al. 1996. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Ann. Neurol. 39:128-31
    • (1996) Ann. Neurol. , vol.39 , pp. 128-131
    • Rouleau, G.A.1    Clark, A.W.2    Rooke, K.3    Pramatarova, A.4    Krizus, A.5
  • 64
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of myotrophic lateral sclerosis
    • Cöté F, Collard J-F, Julien J-P. 1993. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of myotrophic lateral sclerosis. Cell 73:35-46
    • (1993) Cell , vol.73 , pp. 35-46
    • Cöté, F.1    Collard, J.-F.2    Julien, J.-P.3
  • 65
    • 0028788303 scopus 로고
    • A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis
    • Cedarbaum JM, Chapman C, Charatan M, Stambler N, Andrews L. 1995. A phase I study of recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. Clin. Neuropharmacol. 18:515-32
    • (1995) Clin. Neuropharmacol. , vol.18 , pp. 515-532
    • Cedarbaum, J.M.1    Chapman, C.2    Charatan, M.3    Stambler, N.4    Andrews, L.5
  • 66
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y, Sendtner M, Thoenen H. 1990. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J. Neurosci. 10:3507-15
    • (1990) J. Neurosci. , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 67
    • 0026694239 scopus 로고
    • Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
    • Sendtner M, Stockli KA, Thoenen H. 1992. Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol 118:139-48
    • (1992) J. Cell Biol , vol.118 , pp. 139-148
    • Sendtner, M.1    Stockli, K.A.2    Thoenen, H.3
  • 68
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner M, Kreutzberg GW, Thoenen H. 1990. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345:440-49
    • (1990) Nature , vol.345 , pp. 440-449
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 69
    • 0025811297 scopus 로고
    • Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor
    • Oppenheim RW, Prevette D, Qin-Wei Y, Collins F, MacDonald J. 1991. Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor. Science 251:1616-18
    • (1991) Science , vol.251 , pp. 1616-1618
    • Oppenheim, R.W.1    Prevette, D.2    Qin-Wei, Y.3    Collins, F.4    MacDonald, J.5
  • 70
    • 0027450906 scopus 로고
    • Effects of administration of ciliary neurotrophic factor on normal motor and sensory peripheral nerves in vivo
    • Apfel SC, Arezzo JC, Moran M, Kessler JA. 1993. Effects of administration of ciliary neurotrophic factor on normal motor and sensory peripheral nerves in vivo. Brain Res. 604:1-6
    • (1993) Brain Res. , vol.604 , pp. 1-6
    • Apfel, S.C.1    Arezzo, J.C.2    Moran, M.3    Kessler, J.A.4
  • 71
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • Sendtner M, Schmalbruch H, Stockli K A, Carroll P, Kreutzberg G W, Thoenen H. 1992. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358:502-5
    • (1992) Nature , vol.358 , pp. 502-505
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 72
    • 0028021552 scopus 로고
    • A null mutation in the human CNTF gene is not causally related to neurological diseases
    • Takahashi R, Yokoji H, Misawa H, Hayashi M, Hu J, Deguchi T. 1994. A null mutation in the human CNTF gene is not causally related to neurological diseases. Nat. Genet. 7:79-84
    • (1994) Nat. Genet. , vol.7 , pp. 79-84
    • Takahashi, R.1    Yokoji, H.2    Misawa, H.3    Hayashi, M.4    Hu, J.5    Deguchi, T.6
  • 73
    • 0028137577 scopus 로고
    • Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat
    • Dittrich F, Thoenen H, Sendtner, M. 1994. Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat Ann. Neurol. 35:151-63
    • (1994) Ann. Neurol. , vol.35 , pp. 151-163
    • Dittrich, F.1    Thoenen, H.2    Sendtner, M.3
  • 75
    • 0024511528 scopus 로고
    • Insulin-like growth factor (IGF-I) as a stimulator of regeneration in the freeze-injured rat sciatic nerve
    • Sjoberg J, Kanje M. 1989. Insulin-like growth factor (IGF-I) as a stimulator of regeneration in the freeze-injured rat sciatic nerve. Brain Res. 485:102-8
    • (1989) Brain Res. , vol.485 , pp. 102-108
    • Sjoberg, J.1    Kanje, M.2
  • 78
    • 1542374239 scopus 로고
    • Relationship of insulin-like growth factor II gene expression in muscle to synaptogenesis
    • Ishii D. 1989. Relationship of insulin-like growth factor II gene expression in muscle to synaptogenesis. Proc. Natl. Acad. Sci. USA 86:2898-902
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2898-2902
    • Ishii, D.1
  • 79
    • 0026691620 scopus 로고
    • Effects of astrocytes insulin and insulin-like growth factor I on the survival of motoneurons in vitro
    • Ang LC, Bhaumick B, Munoz DG, Sass J, Juurlink BHJ. 1992. Effects of astrocytes insulin and insulin-like growth factor I on the survival of motoneurons in vitro. J. Neurol. Sci. 109:168-172
    • (1992) J. Neurol. Sci. , vol.109 , pp. 168-172
    • Ang, L.C.1    Bhaumick, B.2    Munoz, D.G.3    Sass, J.4    Juurlink, B.H.J.5
  • 80
    • 0028134877 scopus 로고
    • Expression of insulin-like growth factor-I and related peptides during motoneuron regeneration
    • Gehrmann J, Yao DL, Bonetti B, Bondy CA, Brenner M, et al. 1994. Expression of insulin-like growth factor-I and related peptides during motoneuron regeneration. Exp. Neurol. 128:202-10
    • (1994) Exp. Neurol. , vol.128 , pp. 202-210
    • Gehrmann, J.1    Yao, D.L.2    Bonetti, B.3    Bondy, C.A.4    Brenner, M.5
  • 81
    • 0030047158 scopus 로고    scopus 로고
    • Characterization of insulin-like growth factor-I and its receptor binding proteins in transected nerves and cultured Schwann cells
    • Cheng H-L, Randolph A, Yee D, Delafontaine P, Tennekoon G, Feldman E L. 1996. Characterization of insulin-like growth factor-I and its receptor binding proteins in transected nerves and cultured Schwann cells. J. Neurochem. 66:525-36
    • (1996) J. Neurochem. , vol.66 , pp. 525-536
    • Cheng, H.-L.1    Randolph, A.2    Yee, D.3    Delafontaine, P.4    Tennekoon, G.5    Feldman, E.L.6
  • 82
    • 0027481752 scopus 로고
    • Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
    • Koliatsos VE, Clatterbuck RE, Winslow JW, Cayouette MH, Price DL. 1993. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron 10:359-67
    • (1993) Neuron , vol.10 , pp. 359-367
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Winslow, J.W.3    Cayouette, M.H.4    Price, D.L.5
  • 83
    • 0023930477 scopus 로고
    • Transient expression of NGF-receptor-like immunoreactivity in postnatal rat brain and spinal cord
    • Eckenstein F. 1988. Transient expression of NGF-receptor-like immunoreactivity in postnatal rat brain and spinal cord. Brain Res. 446:149-54
    • (1988) Brain Res. , vol.446 , pp. 149-154
    • Eckenstein, F.1
  • 84
    • 0024679252 scopus 로고
    • Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
    • Ernfors P, Henschen A, Olson L, Persson H. 1989. Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron 2:1605-13
    • (1989) Neuron , vol.2 , pp. 1605-1613
    • Ernfors, P.1    Henschen, A.2    Olson, L.3    Persson, H.4
  • 85
    • 0030005125 scopus 로고    scopus 로고
    • Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy
    • Kobayashi NR, Bedard AM, Hincke MT, Tetzlaff W. 1996. Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy. Eur. J. Neurosci. 8:1018-29
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1018-1029
    • Kobayashi, N.R.1    Bedard, A.M.2    Hincke, M.T.3    Tetzlaff, W.4
  • 86
    • 0027318116 scopus 로고
    • Neurotrophins promote motor neuron survival and are present in embryonic limb bud
    • Henderson CE, Camu W, Mettling C, Gouin A, Poulsen K, et al. 1993. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363:266-70
    • (1993) Nature , vol.363 , pp. 266-270
    • Henderson, C.E.1    Camu, W.2    Mettling, C.3    Gouin, A.4    Poulsen, K.5
  • 87
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • Oppenheim RW, Yin QW, Prevette D, Yan Q. 1992. Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 360:755-57
    • (1992) Nature , vol.360 , pp. 755-757
    • Oppenheim, R.W.1    Yin, Q.W.2    Prevette, D.3    Yan, Q.4
  • 88
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan Q, Elliott J, Snider WD. 1992. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360:753-55
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 89
    • 0027969192 scopus 로고
    • The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor
    • Yan Q, Matheson C, Lopez OT, Miller JA. 1994. The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor. J. Neurosci. 14:5281-91
    • (1994) J. Neurosci. , vol.14 , pp. 5281-5291
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3    Miller, J.A.4
  • 90
    • 0026592371 scopus 로고
    • Clinical observations and experiments in diabetic neuropathy
    • Watkins PJ. 1992. Clinical observations and experiments in diabetic neuropathy. Diabetologia 35:2-11
    • (1992) Diabetologia , vol.35 , pp. 2-11
    • Watkins, P.J.1
  • 91
    • 0025317838 scopus 로고
    • Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family
    • Hohn A, Leibrock J, Bailey K, Barde YA. 1990. Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family. Nature 344:339-41
    • (1990) Nature , vol.344 , pp. 339-341
    • Hohn, A.1    Leibrock, J.2    Bailey, K.3    Barde, Y.A.4
  • 92
    • 0028289478 scopus 로고
    • Expression and co-expression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
    • McMahon SB, Armanini MP, Ling L, Phillips HS. 1994. Expression and co-expression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets. Neuron 12:1161-71
    • (1994) Neuron , vol.12 , pp. 1161-1171
    • McMahon, S.B.1    Armanini, M.P.2    Ling, L.3    Phillips, H.S.4
  • 93
    • 0344046620 scopus 로고
    • Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons
    • Gorin MD, Johnson EM. 1979. Experimental autoimmune model of nerve growth factor deprivation: effects on developing peripheral sympathetic and sensory neurons. Proc. Natl. Acad. Sci. USA 76:5382-86
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5382-5386
    • Gorin, M.D.1    Johnson, E.M.2
  • 94
    • 0026784969 scopus 로고
    • Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses to injury and infusion of NGF
    • Verge VMK, Merlio JP, Grondin J, Ernfors P, Persson H, et al. 1992. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. J. Neurosci. 12:4011-22
    • (1992) J. Neurosci. , vol.12 , pp. 4011-4022
    • Verge, V.M.K.1    Merlio, J.P.2    Grondin, J.3    Ernfors, P.4    Persson, H.5
  • 96
  • 97
    • 0026559892 scopus 로고
    • Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF
    • Diamond J, Foerster A, Holmes M, Coughlin M. 1991. Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF. J. Neurosci. 12:1467-76
    • (1991) J. Neurosci. , vol.12 , pp. 1467-1476
    • Diamond, J.1    Foerster, A.2    Holmes, M.3    Coughlin, M.4
  • 98
    • 0026560958 scopus 로고
    • Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat
    • Diamond J, Holmes M, Coughlin M. 1991. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat. J. Neurosci. 12:1454-66
    • (1991) J. Neurosci. , vol.12 , pp. 1454-1466
    • Diamond, J.1    Holmes, M.2    Coughlin, M.3
  • 100
    • 0027967044 scopus 로고
    • The effect of systemically administered recombinant human nerve growth factor in healthy human subjects
    • Petty BG, Cornblath DR, Adornato BT, Chaudhry V, Flexner C, et al. 1994. The effect of systemically administered recombinant human nerve growth factor in healthy human subjects. Ann. Neurol. 36:244-46
    • (1994) Ann. Neurol. , vol.36 , pp. 244-246
    • Petty, B.G.1    Cornblath, D.R.2    Adornato, B.T.3    Chaudhry, V.4    Flexner, C.5
  • 101
    • 0027406813 scopus 로고
    • Nerve growth factor-induced hyperalgesia in the neonatal and adult rat
    • Lewin GR, Ritter AM, Mendell LM. 1993. Nerve growth factor-induced hyperalgesia in the neonatal and adult rat J. Comp. Neurol. 13:2136-48
    • (1993) J. Comp. Neurol. , vol.13 , pp. 2136-2148
    • Lewin, G.R.1    Ritter, A.M.2    Mendell, L.M.3
  • 102
    • 0026665416 scopus 로고
    • Nerve growth factor mRNA content parallels altered sympathetic innervation in the spontaneously hypertensive rat
    • Falckh PH, Harkin LA, Head RJ. 1992. Nerve growth factor mRNA content parallels altered sympathetic innervation in the spontaneously hypertensive rat. Clin. Exp. Pharmacol. Physiol. 19:541-45
    • (1992) Clin. Exp. Pharmacol. Physiol. , vol.19 , pp. 541-545
    • Falckh, P.H.1    Harkin, L.A.2    Head, R.J.3
  • 103
    • 0026759529 scopus 로고
    • Beta-nerve growth factor influences the expression of androgen-binding protein messenger ribonucleic acid in rat testis
    • Lonnerberg P, Soder O, Parvinen M, Ritzen EM, Persson H. 1992. Beta-nerve growth factor influences the expression of androgen-binding protein messenger ribonucleic acid in rat testis. Biol. Reprod. 47:381-88
    • (1992) Biol. Reprod. , vol.47 , pp. 381-388
    • Lonnerberg, P.1    Soder, O.2    Parvinen, M.3    Ritzen, E.M.4    Persson, H.5
  • 104
    • 0029898913 scopus 로고    scopus 로고
    • Nerve growth factor is an autocrine survival factor for memory B lymphocytes
    • Torcia M, Bracci-Laudiero L, Lucibello M, Nencioni L, Labardi D, et al. 1996. Nerve growth factor is an autocrine survival factor for memory B lymphocytes. Cell 85:345-56
    • (1996) Cell , vol.85 , pp. 345-356
    • Torcia, M.1    Bracci-Laudiero, L.2    Lucibello, M.3    Nencioni, L.4    Labardi, D.5
  • 105
    • 0022499601 scopus 로고
    • Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels
    • Mazurek N, Weskamp G, Erne P, Otten U. 1986. Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels. FEBS Lett. 198:29-43
    • (1986) FEBS Lett. , vol.198 , pp. 29-43
    • Mazurek, N.1    Weskamp, G.2    Erne, P.3    Otten, U.4
  • 106
    • 0028052149 scopus 로고
    • Selective expression of neurotrophin-3 messenger RNA in muscle spindles of the rat
    • Copray JCVM, Brouwer N. 1994. Selective expression of neurotrophin-3 messenger RNA in muscle spindles of the rat. Neuroscience 63:1125-35
    • (1994) Neuroscience , vol.63 , pp. 1125-1135
    • Copray, J.C.V.M.1    Brouwer, N.2
  • 107
    • 0029002671 scopus 로고
    • Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy
    • Gao W-Q, Dybdal N, Shinsky N, Murnane A, Schmelzer C, et al. 1995. Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy. Ann. Neurol. 38:30-37
    • (1995) Ann. Neurol. , vol.38 , pp. 30-37
    • Gao, W.-Q.1    Dybdal, N.2    Shinsky, N.3    Murnane, A.4    Schmelzer, C.5
  • 108
    • 0029166169 scopus 로고
    • Heterodimeric neurotrophins induce phosphorylation of trk receptors and promote neuronal differentiation
    • Treanor JJS, Schmelzer C, Winslow JW, Nikolics K, Hefti F, Burton L E. 1995. Heterodimeric neurotrophins induce phosphorylation of trk receptors and promote neuronal differentiation. J. Biol. Chem. 270:23104-110
    • (1995) J. Biol. Chem. , vol.270 , pp. 23104-23110
    • Treanor, J.J.S.1    Schmelzer, C.2    Winslow, J.W.3    Nikolics, K.4    Hefti, F.5    Burton, L.E.6
  • 109
    • 0028559164 scopus 로고
    • The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin
    • Urfer R, Tsoulfas P, Soppet D, Escandon E, Parada LF, Presta LG. 1994. The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. EMBO J. 13:5896-909
    • (1994) EMBO J. , vol.13 , pp. 5896-5909
    • Urfer, R.1    Tsoulfas, P.2    Soppet, D.3    Escandon, E.4    Parada, L.F.5    Presta, L.G.6
  • 110
    • 0025893945 scopus 로고
    • Parkinson's disease: Pathophysiology
    • Agid Y. 1991. Parkinson's disease: pathophysiology. Lancet 337:1321-27
    • (1991) Lancet , vol.337 , pp. 1321-1327
    • Agid, Y.1
  • 111
    • 0026022504 scopus 로고
    • Promotion of central cholinergic and dopaminergic neuron differentiation by brain-dervived neurotrophic factor but not neurotrophin-3
    • Knusel B, Winslow JW, Rosenthal A, Burton LE, Seid DP, et al. 1991. Promotion of central cholinergic and dopaminergic neuron differentiation by brain-dervived neurotrophic factor but not neurotrophin-3. Proc. Natl. Acad. Sci. USA 88:961-65
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 961-965
    • Knusel, B.1    Winslow, J.W.2    Rosenthal, A.3    Burton, L.E.4    Seid, D.P.5
  • 112
    • 0025876757 scopus 로고
    • BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
    • Hyman C, Hofer M, Barde YA, Juhasz M, Yancopoulos GD, et al. 1991. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 350:230-33
    • (1991) Nature , vol.350 , pp. 230-233
    • Hyman, C.1    Hofer, M.2    Barde, Y.A.3    Juhasz, M.4    Yancopoulos, G.D.5
  • 113
    • 0002648530 scopus 로고
    • Pretreatment of dopaminergic neurons in culture with brain-derived neurotrophic factor attenuates toxicity of 1-methyl-4-pyridinium
    • Beck KD, Knusel B, Winslow JW, Rosenthal A, Burton LE. 1992. Pretreatment of dopaminergic neurons in culture with brain-derived neurotrophic factor attenuates toxicity of 1-methyl-4-pyridinium. Neurodegeneration 1:27-36
    • (1992) Neurodegeneration , vol.1 , pp. 27-36
    • Beck, K.D.1    Knusel, B.2    Winslow, J.W.3    Rosenthal, A.4    Burton, L.E.5
  • 114
    • 0026689954 scopus 로고
    • Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system
    • Spina MB, Squinto SP, Miller J, Lindsay RM, Hyman C. 1992. Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system. J. Neurochem. 59:99-106
    • (1992) J. Neurochem. , vol.59 , pp. 99-106
    • Spina, M.B.1    Squinto, S.P.2    Miller, J.3    Lindsay, R.M.4    Hyman, C.5
  • 115
    • 0027460309 scopus 로고
    • FGF-2 mediated protection of cultured mesencephalic dopaminergic neurons against MPTP and MPP+: Specificity and impact of culture conditions, non-dopaminergic neurons, and astroglial cells
    • Otto D, Unsicker K. 1993. FGF-2 mediated protection of cultured mesencephalic dopaminergic neurons against MPTP and MPP+: specificity and impact of culture conditions, non-dopaminergic neurons, and astroglial cells. J. Neurosci. Res. 34:382-93
    • (1993) J. Neurosci. Res. , vol.34 , pp. 382-393
    • Otto, D.1    Unsicker, K.2
  • 116
    • 0026574673 scopus 로고
    • Brain-derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain
    • Knüsel B, Beck KD, Winslow JW, Rosenthal A, Burton LE, et al. 1992. Brain-derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain. J. Neurosci. 12:4391-402
    • (1992) J. Neurosci. , vol.12 , pp. 4391-4402
    • Knüsel, B.1    Beck, K.D.2    Winslow, J.W.3    Rosenthal, A.4    Burton, L.E.5
  • 117
    • 0026482150 scopus 로고
    • Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo
    • Altar CA, Boylan CB, Jackson C, Hershenson S, Miller J, et al. 1992. Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo. Proc. Natl. Acad. Sci. USA 89:11347-51
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11347-11351
    • Altar, C.A.1    Boylan, C.B.2    Jackson, C.3    Hershenson, S.4    Miller, J.5
  • 118
    • 0027407015 scopus 로고
    • Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection
    • Lapchak PA, Beck KD, Araujo DM, Irwin I, Langston JW, Hefti F. 1993. Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neuroscience 53:639-50
    • (1993) Neuroscience , vol.53 , pp. 639-650
    • Lapchak, P.A.1    Beck, K.D.2    Araujo, D.M.3    Irwin, I.4    Langston, J.W.5    Hefti, F.6
  • 119
    • 0027502622 scopus 로고
    • Expression of members of the trk family in the developing postnatal rat brain
    • Ringstedt T, Lagercrantz H, Persson H. 1993. Expression of members of the trk family in the developing postnatal rat brain. Dev. Brain Res. 72:119-31
    • (1993) Dev. Brain Res. , vol.72 , pp. 119-131
    • Ringstedt, T.1    Lagercrantz, H.2    Persson, H.3
  • 121
    • 0027731592 scopus 로고
    • Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo
    • Strömberg I, Björklund L, Johansson M, Tomac A, Collins F, et al. 1993. Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp. Neurol. 124:401-12
    • (1993) Exp. Neurol. , vol.124 , pp. 401-412
    • Strömberg, I.1    Björklund, L.2    Johansson, M.3    Tomac, A.4    Collins, F.5
  • 122
    • 0028834063 scopus 로고
    • Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
    • Tomac A, Lindqvist E, Lin L-F H, Ögren SO. Young D, et al. 1995. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373:335
    • (1995) Nature , vol.373 , pp. 335
    • Tomac, A.1    Lindqvist, E.2    Lin, L.-F.H.3    Ögren, S.O.4    Young, D.5
  • 123
    • 0028795044 scopus 로고
    • GDNF protects mesencephalic dopaminergic neurons from axotomy-induced degeneration in the adult brain
    • Beck KD, Valverde J, Poulsen K, Moffat B, Alexi T, et al. 1995. GDNF protects mesencephalic dopaminergic neurons from axotomy-induced degeneration in the adult brain. Nature 373:339-41
    • (1995) Nature , vol.373 , pp. 339-341
    • Beck, K.D.1    Valverde, J.2    Poulsen, K.3    Moffat, B.4    Alexi, T.5
  • 124
    • 0029047329 scopus 로고
    • Glial cell line-derived neurotrophic factor but not transforming growth factor beta-3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
    • Sauer H, Rosenblad C, Bjorklund A. 1995. Glial cell line-derived neurotrophic factor but not transforming growth factor beta-3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc. Natl. Acad. Sci. USA 92:8935-39
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8935-8939
    • Sauer, H.1    Rosenblad, C.2    Bjorklund, A.3
  • 130
    • 0028109717 scopus 로고
    • GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle
    • Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, et al. 1994. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-64
    • (1994) Science , vol.266 , pp. 1062-1064
    • Henderson, C.E.1    Phillips, H.S.2    Pollock, R.A.3    Davies, A.M.4    Lemeulle, C.5
  • 132
    • 0029950147 scopus 로고    scopus 로고
    • GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice
    • Sagot Y, Tan SA, Hammang JP, Aebischer P, Kato AC. 1996. GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. Neuroscience 16:2335-41
    • (1996) Neuroscience , vol.16 , pp. 2335-2341
    • Sagot, Y.1    Tan, S.A.2    Hammang, J.P.3    Aebischer, P.4    Kato, A.C.5
  • 133
    • 0028981289 scopus 로고
    • Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells
    • Mount HTJ, Dean DO, Alberch J, Dreyfus CF, Black IB. 1995. Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc. Natl. Acad. Sci. USA 92:9092-96
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9092-9096
    • Mount, H.T.J.1    Dean, D.O.2    Alberch, J.3    Dreyfus, C.F.4    Black, I.B.5
  • 134
    • 0029584686 scopus 로고
    • GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo
    • Arenas E, Trupp M, Åkerud P, Ibáñez CF. 1995. GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15:1465-73
    • (1995) Neuron , vol.15 , pp. 1465-1473
    • Arenas, E.1    Trupp, M.2    Åkerud, P.3    Ibáñez, C.F.4
  • 135
    • 0030024846 scopus 로고    scopus 로고
    • Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions
    • Hellmich HL, Kos L, Cho ES, Mahon KA, Zimmer A. 1996. Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech. Dev. 54:95-105
    • (1996) Mech. Dev. , vol.54 , pp. 95-105
    • Hellmich, H.L.1    Kos, L.2    Cho, E.S.3    Mahon, K.A.4    Zimmer, A.5
  • 136
    • 0030007849 scopus 로고    scopus 로고
    • Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization
    • Suvanto P, Hiltunen JO, Arumäe U, Moshnyakow M, Sariola H, et al. 1996. Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization. Eur. J. Neurosci. 8:816-22
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 816-822
    • Suvanto, P.1    Hiltunen, J.O.2    Arumäe, U.3    Moshnyakow, M.4    Sariola, H.5
  • 138
    • 0030065375 scopus 로고    scopus 로고
    • Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts
    • Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V. 1996. Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development 122:349-58
    • (1996) Development , vol.122 , pp. 349-358
    • Durbec, P.L.1    Larsson-Blomberg, L.B.2    Schuchardt, A.3    Costantini, F.4    Pachnis, V.5
  • 139
    • 0026440987 scopus 로고
    • Cortical biopsy in Alzheimer's disease: Diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations
    • DeKosky ST, Harbaugh RE, Schmitt FA, Bakay RAE, Chui HC, et al. 1992. Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Ann. Neurol. 32:625-32
    • (1992) Ann. Neurol. , vol.32 , pp. 625-632
    • DeKosky, S.T.1    Harbaugh, R.E.2    Schmitt, F.A.3    Bakay, R.A.E.4    Chui, H.C.5
  • 140
    • 0027511796 scopus 로고
    • Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease
    • Lehericy S, Hirsch EC, Cervera-Pierot P, Hersh LB, Bakchine S, et al. 1993. Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease. J. Comp. Neurol. 330:15-31
    • (1993) J. Comp. Neurol. , vol.330 , pp. 15-31
    • Lehericy, S.1    Hirsch, E.C.2    Cervera-Pierot, P.3    Hersh, L.B.4    Bakchine, S.5
  • 141
  • 142
    • 0028017748 scopus 로고
    • Molecular strategies for the first generations of antidementia drugs (I). Tacrine and related compounds
    • Cacabelos R, Nordberg A, Caamaño J, Franco-Maside A, Fernández-Novoa L, et al. 1994. Molecular strategies for the first generations of antidementia drugs (I). Tacrine and related compounds. Drugs Today 30:295-337
    • (1994) Drugs Today , vol.30 , pp. 295-337
    • Cacabelos, R.1    Nordberg, A.2    Caamaño, J.3    Franco-Maside, A.4    Fernández-Novoa, L.5
  • 143
    • 0024394332 scopus 로고
    • Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
    • Hefti F, Hartikka J, Knusel B. 1989. Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases. Neurobiol. Aging 10:515-33
    • (1989) Neurobiol. Aging , vol.10 , pp. 515-533
    • Hefti, F.1    Hartikka, J.2    Knusel, B.3
  • 144
    • 0029979933 scopus 로고    scopus 로고
    • Nerve growth factor, ageing and Alzheimer's Disease
    • Sofroniew MV. 1996. Nerve growth factor, ageing and Alzheimer's Disease. Alzheimer's Res 2:7-14
    • (1996) Alzheimer's Res , vol.2 , pp. 7-14
    • Sofroniew, M.V.1
  • 145
    • 0021359024 scopus 로고
    • Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with septo-hippocampal lesions
    • Hefti F, Dravid A, Hartikka J. 1984. Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with septo-hippocampal lesions. Brain Res. 293:305-11
    • (1984) Brain Res. , vol.293 , pp. 305-311
    • Hefti, F.1    Dravid, A.2    Hartikka, J.3
  • 146
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neurons atrophy and spatial memory impairment in aged rats by nerve growth factor
    • Fischer W, Wictorin K, Bjorklund A, Williams LR. Varon S, Gage FH. 1987. Amelioration of cholinergic neurons atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 329:65-68
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Bjorklund, A.3    Williams, L.R.4    Varon, S.5    Gage, F.H.6
  • 147
    • 0022245786 scopus 로고
    • Behavioral and neurochemical effects of chronic intraventricular injections of nerve growth factor in adult rats with fimbria lesions
    • Will B, Hefti F. 1985. Behavioral and neurochemical effects of chronic intraventricular injections of nerve growth factor in adult rats with fimbria lesions. Behav. Brain Res. 17:17-24
    • (1985) Behav. Brain Res. , vol.17 , pp. 17-24
    • Will, B.1    Hefti, F.2
  • 149
    • 0027217466 scopus 로고
    • TrkA NGF receptor expression by non-cholinergic thalamic neurons
    • Venero JL, Hefti F. 1993. TrkA NGF receptor expression by non-cholinergic thalamic neurons. NeuroReport 4:959-62
    • (1993) NeuroReport , vol.4 , pp. 959-962
    • Venero, J.L.1    Hefti, F.2
  • 150
    • 0026042565 scopus 로고
    • Messenger RNAs for trk and the low-affinity NGF receptor in rat basal forebrain
    • Vazquez ME, Ebendahl T. 1991. Messenger RNAs for trk and the low-affinity NGF receptor in rat basal forebrain. NeuroReport 2:593-96
    • (1991) NeuroReport , vol.2 , pp. 593-596
    • Vazquez, M.E.1    Ebendahl, T.2
  • 151
    • 0342433113 scopus 로고
    • Nerve growth factor therapy for Alzheimer's disease: Comparison with brain-derived neurotrophic factor
    • ed. K Iqbal, JA Mortimer, B Winblad, HM Wisniewski, New York: Wiley & Sons
    • Hefti F, Venero JL, Widmer HR, Knusel B. 1995. Nerve growth factor therapy for Alzheimer's disease: comparison with brain-derived neurotrophic factor. In Research Advances in Alzheimer's Disease and Related Disorders, ed. K Iqbal, JA Mortimer, B Winblad, HM Wisniewski, pp. 321-28. New York: Wiley & Sons
    • (1995) Research Advances in Alzheimer's Disease and Related Disorders , pp. 321-328
    • Hefti, F.1    Venero, J.L.2    Widmer, H.R.3    Knusel, B.4
  • 152
    • 0028334932 scopus 로고
    • Highly selective effects of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 on intact and injured basal forebrain
    • Koliatsos VE, Price DL, Gouras GK, Cayouette MH, Burton LE, Winslow JW. 1994. Highly selective effects of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 on intact and injured basal forebrain. J. Comp. Neurol. 343:247-62
    • (1994) J. Comp. Neurol. , vol.343 , pp. 247-262
    • Koliatsos, V.E.1    Price, D.L.2    Gouras, G.K.3    Cayouette, M.H.4    Burton, L.E.5    Winslow, J.W.6
  • 153
    • 0028064960 scopus 로고
    • Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5, but not by brain-derived neurotrophic factor
    • Fischer W, Sirevaag A, Wiegand SJ, Lindsay RM, Björklund A. 1994. Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5, but not by brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA 91:8607-11
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8607-8611
    • Fischer, W.1    Sirevaag, A.2    Wiegand, S.J.3    Lindsay, R.M.4    Björklund, A.5
  • 154
    • 0027348445 scopus 로고
    • Pharmacology of nerve growth factor in the brain
    • Orlando: Academic
    • Hefti F, Lapchak PA. 1993. Pharmacology of nerve growth factor in the brain. In Advances in Pharmacology, 24:239-73. Orlando: Academic
    • (1993) Advances in Pharmacology , vol.24 , pp. 239-273
    • Hefti, F.1    Lapchak, P.A.2
  • 155
    • 0026512910 scopus 로고
    • Nerve growth factor affects 11C-nicotine binding, blood flow, EEG and verbal episodic memory in an Alzheimer patient
    • Olson L, Nordberg A, von Holst H, Backman L, Ebendahl T, et al. 1992. Nerve growth factor affects 11C-nicotine binding, blood flow, EEG and verbal episodic memory in an Alzheimer patient. J. Neurol. Transm. [P-D Sect] 4:79-95
    • (1992) J. Neurol. Transm. [P-D Sect] , vol.4 , pp. 79-95
    • Olson, L.1    Nordberg, A.2    Von Holst, H.3    Backman, L.4    Ebendahl, T.5
  • 156
    • 0011178278 scopus 로고
    • Induction of Schwann cell hyperplasia in vivo after intracerebroventricular admiistration of nerve growth factor
    • Winkler J, Ramirez GA, Kuhn HG, Peterson DA, Tuszynski MH, et al. 1995. Induction of Schwann cell hyperplasia in vivo after intracerebroventricular admiistration of nerve growth factor. Soc. Neurosci. Abstr. 21:119.1
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 1191
    • Winkler, J.1    Ramirez, G.A.2    Kuhn, H.G.3    Peterson, D.A.4    Tuszynski, M.H.5
  • 157
    • 0026768176 scopus 로고
    • bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy
    • Cummings BJ, Yee GJ, Cotman CW. 1992. bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy. Brain Res. 591:271-76
    • (1992) Brain Res. , vol.591 , pp. 271-276
    • Cummings, B.J.1    Yee, G.J.2    Cotman, C.W.3
  • 158
    • 0029873038 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death
    • Peterson DA, Lucidi-Phillipi CA, Murphy DP, Ray J, Gage FH. 1996. Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. J. Neurosci. 16:886-98
    • (1996) J. Neurosci. , vol.16 , pp. 886-898
    • Peterson, D.A.1    Lucidi-Phillipi, C.A.2    Murphy, D.P.3    Ray, J.4    Gage, F.H.5
  • 159
    • 0027459266 scopus 로고
    • Differential actions of neurotrophins in the locus coeruleus and basal forebrain
    • Friedman WJ, Ibanez CF, Hallbook F, Persson H, Cain LD, et al. 1993. Differential actions of neurotrophins in the locus coeruleus and basal forebrain. Exp. Neurol. 119:72-78
    • (1993) Exp. Neurol. , vol.119 , pp. 72-78
    • Friedman, W.J.1    Ibanez, C.F.2    Hallbook, F.3    Persson, H.4    Cain, L.D.5
  • 160
    • 0027457183 scopus 로고
    • Ciliary neurotropic factor prevents retrograde neuronal death the adult central nervous system
    • Clatterbuck RE, Price DL, Koliatsos VE. 1993. Ciliary neurotropic factor prevents retrograde neuronal death the adult central nervous system. Proc. Natl. Acad. Sci. USA 90:2222-26
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2222-2226
    • Clatterbuck, R.E.1    Price, D.L.2    Koliatsos, V.E.3
  • 161
    • 0029989784 scopus 로고    scopus 로고
    • BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo
    • Giehl KM, Tetzlaff W. 1996. BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo. Eur. J. Neurosci. 8:1167-75
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1167-1175
    • Giehl, K.M.1    Tetzlaff, W.2
  • 163
    • 0026521942 scopus 로고
    • IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage
    • Cheng B, Mattson MP. 1992. IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage. J. Neurosci. 12:1558-66
    • (1992) J. Neurosci. , vol.12 , pp. 1558-1566
    • Cheng, B.1    Mattson, M.P.2
  • 164
    • 0025885723 scopus 로고
    • Amelioration of delayed neuronal death in the hippocampus by nerve growth factor
    • Shigeno T, Mima T, Takakura K, Graham DI, Kato G, et al. 1991. Amelioration of delayed neuronal death in the hippocampus by nerve growth factor. J. Neurosci. 11:2914-19
    • (1991) J. Neurosci. , vol.11 , pp. 2914-2919
    • Shigeno, T.1    Mima, T.2    Takakura, K.3    Graham, D.I.4    Kato, G.5
  • 166
    • 0028107446 scopus 로고
    • Intraventricular administration of insulin and IGF-1 in transient forebrain ischemia
    • Zhu CZ, Auer RN. 1994. Intraventricular administration of insulin and IGF-1 in transient forebrain ischemia. J. Cereb. Blood Flow Me tab. 14:237-42
    • (1994) J. Cereb. Blood Flow Me Tab. , vol.14 , pp. 237-242
    • Zhu, C.Z.1    Auer, R.N.2
  • 167
    • 0028040062 scopus 로고
    • The role of brain-derived neurotrophic factor in transient forebrain ischaemia in the rat brain
    • Tsukahara T, Yonekawa MD, Tanaka K, Ohara O, Watanabe S, et al. 1994. The role of brain-derived neurotrophic factor in transient forebrain ischaemia in the rat brain. Neurosurgery 34:323
    • (1994) Neurosurgery , vol.34 , pp. 323
    • Tsukahara, T.1    Yonekawa, M.D.2    Tanaka, K.3    Ohara, O.4    Watanabe, S.5
  • 168
    • 0029814228 scopus 로고    scopus 로고
    • Neurotrophin-4/5 treatment reduces infarct size in rats with middle cerebral artery occlusion
    • Chan K-M, Lam D-TN, Pong K, Widmer HR, Hefti F. 1996. Neurotrophin-4/5 treatment reduces infarct size in rats with middle cerebral artery occlusion. Neurochem. Res. 21:769-73
    • (1996) Neurochem. Res. , vol.21 , pp. 769-773
    • Chan, K.-M.1    Lam, D.-T.N.2    Pong, K.3    Widmer, H.R.4    Hefti, F.5
  • 170
    • 0028341483 scopus 로고
    • Brain-derived neurotrophic factor protects against ischaemic cell damage in rat hippocampus
    • Beck T, Lindholm D, Castrén E, Wree A. 1994. Brain-derived neurotrophic factor protects against ischaemic cell damage in rat hippocampus. J. Cereb. Blond Flow Metab. 14:689-92
    • (1994) J. Cereb. Blond Flow Metab. , vol.14 , pp. 689-692
    • Beck, T.1    Lindholm, D.2    Castrén, E.3    Wree, A.4
  • 171
    • 0028808842 scopus 로고
    • Effect of local administration of basic fibroblast growth factor against neuronal damage caused by transient intracerebral mass lesion in rats
    • Kawakami N, Kashiwagi S, Kitahara T, Yamashita T, Ito H. 1995. Effect of local administration of basic fibroblast growth factor against neuronal damage caused by transient intracerebral mass lesion in rats. Brain Res. 697:104-11
    • (1995) Brain Res. , vol.697 , pp. 104-111
    • Kawakami, N.1    Kashiwagi, S.2    Kitahara, T.3    Yamashita, T.4    Ito, H.5
  • 172
    • 0027484293 scopus 로고
    • Mice expressing a bovine basic fibroblast growth factor transgene in the brain show increased resistance to hypoxemic-ischemic cerebral damage
    • MacMillan V, Judge D, Wiseman A, Settles D, Swain J, Davis J. 1993. Mice expressing a bovine basic fibroblast growth factor transgene in the brain show increased resistance to hypoxemic-ischemic cerebral damage. Stroke 24:1735-39
    • (1993) Stroke , vol.24 , pp. 1735-1739
    • MacMillan, V.1    Judge, D.2    Wiseman, A.3    Settles, D.4    Swain, J.5    Davis, J.6
  • 173
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A co-ordinated immunological attach against myelin in the central nervous system
    • Steinman L. 1996. Multiple sclerosis: a co-ordinated immunological attach against myelin in the central nervous system. Cell 85:299-302
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 174
    • 0022542180 scopus 로고
    • Changes in insulin and transferrin requirements of pure brain neuronal cultures during embryonic development
    • Aizenman Y, Weischsel ME Jr, De Vellis J. 1986. Changes in insulin and transferrin requirements of pure brain neuronal cultures during embryonic development. Proc. Natl. Acad. Sci. USA 83:2263-66
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2263-2266
    • Aizenman, Y.1    Weischsel M.E., Jr.2    De Vellis, J.3
  • 175
    • 0025265681 scopus 로고
    • Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, and the insulin-like growth factors
    • Knusel B, Michel PP, Schwaber J, Hefti F. 1990. Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, and the insulin-like growth factors. J. Neurosci. 10:558-70
    • (1990) J. Neurosci. , vol.10 , pp. 558-570
    • Knusel, B.1    Michel, P.P.2    Schwaber, J.3    Hefti, F.4
  • 177
    • 0027269766 scopus 로고
    • Insulin-like growth factor increases brain growth and central nervous system myelination in transgenic mice
    • Carson MJ, Behringer RR, Brinster RL, McMorris FA. 1993. Insulin-like growth factor increases brain growth and central nervous system myelination in transgenic mice. Neuron 10:729-40
    • (1993) Neuron , vol.10 , pp. 729-740
    • Carson, M.J.1    Behringer, R.R.2    Brinster, R.L.3    McMorris, F.A.4
  • 179
    • 0028941681 scopus 로고
    • Mice homozygous for disrupted insulin-like growth factor I gene display reduced myelination in the CNS and reduced numbers of hippocampal granule and parvalbumin-containing neurons
    • Beck KD, Powell-Braxton L, Widmer HR, Valverde J, Hefti F. 1995. Mice homozygous for disrupted insulin-like growth factor I gene display reduced myelination in the CNS and reduced numbers of hippocampal granule and parvalbumin-containing neurons. Neuron 4:717-30
    • (1995) Neuron , vol.4 , pp. 717-730
    • Beck, K.D.1    Powell-Braxton, L.2    Widmer, H.R.3    Valverde, J.4    Hefti, F.5
  • 180
    • 0029042367 scopus 로고
    • Insulin-like growth factor I treatment reduces demyelination and up-regulates gene expression of myelin-related proteins in experimental autoimmune encephalomyelitis
    • Yao DL, Liu X, Hudson LD, Webster HD. 1995. Insulin-like growth factor I treatment reduces demyelination and up-regulates gene expression of myelin-related proteins in experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 92:6190-94
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6190-6194
    • Yao, D.L.1    Liu, X.2    Hudson, L.D.3    Webster, H.D.4
  • 181
    • 0029279164 scopus 로고
    • Insulin-like growth factor I treatment reduces clinical deficits and lesion severity in acute demyelinating experimental autoimmune encephalomyelitis
    • Liu X, Yao D-L, Webster HdeF. 1995. Insulin-like growth factor I treatment reduces clinical deficits and lesion severity in acute demyelinating experimental autoimmune encephalomyelitis. Multiple Sclerosis 1:2-9
    • (1995) Multiple Sclerosis , vol.1 , pp. 2-9
    • Liu, X.1    Yao, D.-L.2    Webster, H.D.F.3
  • 182
    • 0028359315 scopus 로고
    • Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis
    • Lassmann H, Suchanek G, Ozawa K. 1994. Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis. Ann. Neurol. 36:S42-S46
    • (1994) Ann. Neurol. , vol.36
    • Lassmann, H.1    Suchanek, G.2    Ozawa, K.3
  • 183
    • 0029865402 scopus 로고    scopus 로고
    • The movement of IGF-1 into the brain parenchyma after hypoxic-ischaemic injury
    • Guan J, Skinner SJM, Beilharz EJ, Hua KM, Hodgkinson S, et al. 1996. The movement of IGF-1 into the brain parenchyma after hypoxic-ischaemic injury. NeuroReport 7:632-36
    • (1996) NeuroReport , vol.7 , pp. 632-636
    • Guan, J.1    Skinner, S.J.M.2    Beilharz, E.J.3    Hua, K.M.4    Hodgkinson, S.5
  • 184
    • 0028060282 scopus 로고
    • Pharmacokinetics of nerve growth factor (NGF) following different routes of administration to adult rats
    • Tria MA, Fusco M, Vantini G, Mariot R. 1994. Pharmacokinetics of nerve growth factor (NGF) following different routes of administration to adult rats. Exp. Neurol. 127:178-83
    • (1994) Exp. Neurol. , vol.127 , pp. 178-183
    • Tria, M.A.1    Fusco, M.2    Vantini, G.3    Mariot, R.4
  • 186
    • 0027311025 scopus 로고
    • Down-regulation of phosphatidyl-inositol response to BDNF and NT-3 in cultures of cortical neurons
    • Widmer HR, Ohsawa F, Knusel B, Hefti F. 1993. Down-regulation of phosphatidyl-inositol response to BDNF and NT-3 in cultures of cortical neurons. Brain Res. 614:325-34
    • (1993) Brain Res. , vol.614 , pp. 325-334
    • Widmer, H.R.1    Ohsawa, F.2    Knusel, B.3    Hefti, F.4
  • 187
    • 0029946148 scopus 로고    scopus 로고
    • BDNF down-regulates neurotrophin responsiveness, trkB protein and trkB mRNA levels in cultured rat hippocampal neurons
    • Frank L, Ventimiglia R, Anderson K, Lindsay RM, Rudge JS. 1996. BDNF down-regulates neurotrophin responsiveness, trkB protein and trkB mRNA levels in cultured rat hippocampal neurons. Eur. J. Neurosci. 8:1220-30
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1220-1230
    • Frank, L.1    Ventimiglia, R.2    Anderson, K.3    Lindsay, R.M.4    Rudge, J.S.5
  • 188
    • 0026613071 scopus 로고
    • p140trk mRNA marks NGF-responsive forebrain neurons: Evidence that trk gene expression is induced by NGF
    • Holtzman DM, Li Y, Parada L F, Kinsman S, Mobley WH, et al. 1992. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron 9:465-78
    • (1992) Neuron , vol.9 , pp. 465-478
    • Holtzman, D.M.1    Li, Y.2    Parada, L.F.3    Kinsman, S.4    Mobley, W.H.5
  • 189
    • 0029929873 scopus 로고    scopus 로고
    • Intraparenchymal NGF injections in adult and aged rats induce long-lasting Trk tyrosine phosphorylation
    • Knusel B, Kaplan DR, Hefti F. 1996. Intraparenchymal NGF injections in adult and aged rats induce long-lasting Trk tyrosine phosphorylation. Exp. Neurol. 139:121-30
    • (1996) Exp. Neurol. , vol.139 , pp. 121-130
    • Knusel, B.1    Kaplan, D.R.2    Hefti, F.3
  • 190
    • 0025718569 scopus 로고
    • Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates
    • Koliatsos VE, Clatterbuck RE, Nauta HJW, Knusel B, Burton LE, et al. 1991. Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates. Ann. Neurol. 30:831-40
    • (1991) Ann. Neurol. , vol.30 , pp. 831-840
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Nauta, H.J.W.3    Knusel, B.4    Burton, L.E.5
  • 191
    • 0027335526 scopus 로고
    • Distribution of [125I]nerve growth factor in the rat brain following an intraventricular injection: Sequestration by trkA mRNA expressing septal neurons
    • Lapchak PA, Araujo DM, Carswell S, Hefti F. 1993. Distribution of [125I]nerve growth factor in the rat brain following an intraventricular injection: sequestration by trkA mRNA expressing septal neurons. Neuroscience 54:445-60
    • (1993) Neuroscience , vol.54 , pp. 445-460
    • Lapchak, P.A.1    Araujo, D.M.2    Carswell, S.3    Hefti, F.4
  • 192
    • 0030020475 scopus 로고    scopus 로고
    • Trophic effect of exogenous nerve growth factor on rat striatal cholinergic neurons: Comparison between intraparenchymal and intraventricular administration
    • Venero JL, Hefti F, Knusel B. 1996. Trophic effect of exogenous nerve growth factor on rat striatal cholinergic neurons: comparison between intraparenchymal and intraventricular administration. Mol. Pharm. 49:303-10
    • (1996) Mol. Pharm. , vol.49 , pp. 303-310
    • Venero, J.L.1    Hefti, F.2    Knusel, B.3
  • 193
    • 0007383512 scopus 로고
    • Transnasal and intraventricular delivery of drugs
    • ed. WM Pardridge, New York: Raven
    • Pardridge WM. 1991. Transnasal and intraventricular delivery of drugs. In Peptide Drug Delivery to the Brain, ed. WM Pardridge, pp. 99-122. New York: Raven
    • (1991) Peptide Drug Delivery to the Brain , pp. 99-122
    • Pardridge, W.M.1
  • 194
    • 0025115891 scopus 로고
    • NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a Fimbria-Fornix lesion
    • Hoffman D, Wahlberg L, Aebischer P. 1990. NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a Fimbria-Fornix lesion. Exp. Neurol. 110:39-44
    • (1990) Exp. Neurol. , vol.110 , pp. 39-44
    • Hoffman, D.1    Wahlberg, L.2    Aebischer, P.3
  • 195
    • 0027398553 scopus 로고
    • Blood-brain barrier penetration and in vivo activity of an NGF conjugate
    • Friden PM, Walus LR, Watson P, Doctrow SR, Kozarich JW, et al. 1993. Blood-brain barrier penetration and in vivo activity of an NGF conjugate. Science 259:373-76
    • (1993) Science , vol.259 , pp. 373-376
    • Friden, P.M.1    Walus, L.R.2    Watson, P.3    Doctrow, S.R.4    Kozarich, J.W.5
  • 196
    • 0024263047 scopus 로고
    • Grafting genetically modified cells to the damaged brain: Restorative effects of NGF expression
    • Rosenberg MB, Friedmann T, Robertson RC, Tuszynksi M, Wolff JA, et al. 1988. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science 242:1575-78
    • (1988) Science , vol.242 , pp. 1575-1578
    • Rosenberg, M.B.1    Friedmann, T.2    Robertson, R.C.3    Tuszynksi, M.4    Wolff, J.A.5
  • 197
    • 0028353076 scopus 로고
    • Grafting of nerve growth factor-producing fibroblasts reduces behavioural deficits in rats with lesions of the nucleus basalis magnocellularis
    • Dekker AJ, Winkler J, Ray J, Thai LJ, Gage FH. 1994. Grafting of nerve growth factor-producing fibroblasts reduces behavioural deficits in rats with lesions of the nucleus basalis magnocellularis. Neuroscience 60:299-309
    • (1994) Neuroscience , vol.60 , pp. 299-309
    • Dekker, A.J.1    Winkler, J.2    Ray, J.3    Thai, L.J.4    Gage, F.H.5
  • 198
    • 0029867844 scopus 로고    scopus 로고
    • Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: Neurotrophic effects on cholinergic neurons
    • Martinez-Serrano A, Hantzopoulos PA, Björklund A. 1996. Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons. Eur. J. Neurosci. 8:727-35
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 727-735
    • Martinez-Serrano, A.1    Hantzopoulos, P.A.2    Björklund, A.3
  • 199
    • 0028218083 scopus 로고
    • Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord
    • Tuszynski MH, Peterson DA, Ray J, Baird A, Nakahara Y, Gage FH. 1994. Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp. Neurol. 126:1-4
    • (1994) Exp. Neurol. , vol.126 , pp. 1-4
    • Tuszynski, M.H.1    Peterson, D.A.2    Ray, J.3    Baird, A.4    Nakahara, Y.5    Gage, F.H.6
  • 200
    • 0025797710 scopus 로고
    • Transplantation of polymer encapsulated neurotransmitter secreting cells: Effect of the encapsulation technique
    • Aebischer P, Winn SR, Tresco PA, Jaeger CB, Greene LA. 1991. Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique. J. Biomech. Eng. 113:178-83
    • (1991) J. Biomech. Eng. , vol.113 , pp. 178-183
    • Aebischer, P.1    Winn, S.R.2    Tresco, P.A.3    Jaeger, C.B.4    Greene, L.A.5
  • 201
    • 0028343937 scopus 로고
    • Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons
    • Winn SR, Hammang JP, Emerich DF, Lee A, Palmiter RD, Baetge EE. 1994. Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons. Proc. Natl. Acad. Sci. USA 91:2324-28
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2324-2328
    • Winn, S.R.1    Hammang, J.P.2    Emerich, D.F.3    Lee, A.4    Palmiter, R.D.5    Baetge, E.E.6
  • 202
    • 0028303597 scopus 로고
    • Transfer of the nerve growth factor gene into cell lines and cultured neurons using a defective Herpes Simplex virus vector. Transfer of the NGF gene into cells by a HSV-1 vector
    • Geschwind MD, Kessler JA, Geller AI, Federoff JH. 1994. Transfer of the nerve growth factor gene into cell lines and cultured neurons using a defective Herpes Simplex virus vector. Transfer of the NGF gene into cells by a HSV-1 vector. Mol. Brain Res. 24:327-35
    • (1994) Mol. Brain Res. , vol.24 , pp. 327-335
    • Geschwind, M.D.1    Kessler, J.A.2    Geller, A.I.3    Federoff, J.H.4
  • 203
    • 0028150734 scopus 로고
    • Structure-function relationships in the neurotrophin family
    • Ibanez CF. 1994. Structure-function relationships in the neurotrophin family. J. Neurobiol. 25:1349-61
    • (1994) J. Neurobiol. , vol.25 , pp. 1349-1361
    • Ibanez, C.F.1
  • 204
  • 205
    • 0029829270 scopus 로고    scopus 로고
    • Identification of CNTF residues essential for LIF receptor binding and generation of CNTF receptor antagonists
    • Di Marco A, Gloaguen I, Graziani R, Paonessa G, Saggio I, et al. 1996. Identification of CNTF residues essential for LIF receptor binding and generation of CNTF receptor antagonists. Proc. Natl. Acad. Sci. USA 93:9247-52
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9247-9252
    • Di Marco, A.1    Gloaguen, I.2    Graziani, R.3    Paonessa, G.4    Saggio, I.5
  • 206
    • 0028843912 scopus 로고
    • Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor
    • Sohrabji F, Miranda RCG, Toran-Allerand CD. 1995. Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA 92:11110-14
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11110-11114
    • Sohrabji, F.1    Miranda, R.C.G.2    Toran-Allerand, C.D.3
  • 207
    • 0030058730 scopus 로고    scopus 로고
    • A metabotropic glutamate receptor agonist regulates neurotrophin messenger RNA in rat forebrain
    • Murray KD, Wood PL, Rosasco C, Isackson PJ. 1996. A metabotropic glutamate receptor agonist regulates neurotrophin messenger RNA in rat forebrain. Neuroscience 70:617-30
    • (1996) Neuroscience , vol.70 , pp. 617-630
    • Murray, K.D.1    Wood, P.L.2    Rosasco, C.3    Isackson, P.J.4
  • 208
    • 0028316527 scopus 로고
    • Effect of yohimbine on nerve growth factor mRNA and protein levels in rat hippocampus
    • Stone EA, Manavalan JS, Basham DA, Bing G. 1994. Effect of yohimbine on nerve growth factor mRNA and protein levels in rat hippocampus. Neurosci. Lett. 167:11-13
    • (1994) Neurosci. Lett. , vol.167 , pp. 11-13
    • Stone, E.A.1    Manavalan, J.S.2    Basham, D.A.3    Bing, G.4
  • 209
    • 0027208902 scopus 로고
    • Effects of propentofylline, an NGF synthesis stimulator, on alterations in muscarinic cholinergic receptors induced by basal forebrain lesion in rats
    • Fuji K, Hiramatsu M, Hayashi S, Kameyama T, Nabeshima T. 1993. Effects of propentofylline, an NGF synthesis stimulator, on alterations in muscarinic cholinergic receptors induced by basal forebrain lesion in rats. Neurosci. Lett. 150:99-102
    • (1993) Neurosci. Lett. , vol.150 , pp. 99-102
    • Fuji, K.1    Hiramatsu, M.2    Hayashi, S.3    Kameyama, T.4    Nabeshima, T.5
  • 210
    • 0027522350 scopus 로고
    • Systemic interleukin-1β decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation
    • Lapchak PA, Araujo DM, Hefti F. 1993. Systemic interleukin-1β decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation. Neuroscience 53:297-301
    • (1993) Neuroscience , vol.53 , pp. 297-301
    • Lapchak, P.A.1    Araujo, D.M.2    Hefti, F.3
  • 211
    • 0025286240 scopus 로고
    • Influences of neonatal and adult exposures to testosterone on the levels of the beta-subunit of nerve growth factor in the neural tissues of mice
    • Katoh-Semba R, Semba R, Kashiwamata S, Kalo K. 1990. Influences of neonatal and adult exposures to testosterone on the levels of the beta-subunit of nerve growth factor in the neural tissues of mice. Brain Res. 522:112-17
    • (1990) Brain Res. , vol.522 , pp. 112-117
    • Katoh-Semba, R.1    Semba, R.2    Kashiwamata, S.3    Kalo, K.4
  • 212
    • 0026551310 scopus 로고
    • Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain
    • Toran-Allerand CD, Miranda RC, Bentham WDL, Shrabji F, Brown TJ, et al. 1992. Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain. Proc. Natl. Acad. Sci. USA 89: 4668-72
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4668-4672
    • Toran-Allerand, C.D.1    Miranda, R.C.2    Bentham, W.D.L.3    Shrabji, F.4    Brown, T.J.5
  • 213
    • 0029915861 scopus 로고    scopus 로고
    • The effects of ovariectomy and estrogen replacment on trkA and choline acetyltransferase mRNA expression in the basal forebrain of the adult female Sprague-Dawley rat
    • McMillan PJ, Singer CA, Dorsa DM. 1996. The effects of ovariectomy and estrogen replacment on trkA and choline acetyltransferase mRNA expression in the basal forebrain of the adult female Sprague-Dawley rat. J. Neurosci. 16:1860-65
    • (1996) J. Neurosci. , vol.16 , pp. 1860-1865
    • McMillan, P.J.1    Singer, C.A.2    Dorsa, D.M.3
  • 214
    • 0025125717 scopus 로고
    • Stimulation of nerve growth factor synthesis/secretion by 1,4-benxoquinone and its derivatives in cultured mouse astroglial cells
    • Takeuchi R, Murase K, Furukawa Y, Furukawa S, Hayashi K. 1990. Stimulation of nerve growth factor synthesis/secretion by 1,4-benxoquinone and its derivatives in cultured mouse astroglial cells. FEBS Lett. 261:63-66
    • (1990) FEBS Lett. , vol.261 , pp. 63-66
    • Takeuchi, R.1    Murase, K.2    Furukawa, Y.3    Furukawa, S.4    Hayashi, K.5
  • 215
    • 0026743263 scopus 로고
    • Induction of NGFby isoproterenol, 4-methylcatechol and serum occurs by three distinct mechanisms
    • Carswell S, Hoffman EK, Clopton-Hartpence K, Wilcox HM, Lewis ME. 1992. Induction of NGFby isoproterenol, 4-methylcatechol and serum occurs by three distinct mechanisms. Mol. Brain Res. 15:145-50
    • (1992) Mol. Brain Res. , vol.15 , pp. 145-150
    • Carswell, S.1    Hoffman, E.K.2    Clopton-Hartpence, K.3    Wilcox, H.M.4    Lewis, M.E.5
  • 216
    • 0028266722 scopus 로고
    • The therapeutic effects of 4-methylcatechol, a stimulator of endogenous nerve growth factor synthesis, on experimental diabetic neuropathy in rats
    • Hanaoka Y, Takekazu O, Furukawa S, Furukawa Y, Hayashi K, Matsukura S. 1994. The therapeutic effects of 4-methylcatechol, a stimulator of endogenous nerve growth factor synthesis, on experimental diabetic neuropathy in rats. J. Neurol. Sci. 122:28-32
    • (1994) J. Neurol. Sci. , vol.122 , pp. 28-32
    • Hanaoka, Y.1    Takekazu, O.2    Furukawa, S.3    Furukawa, Y.4    Hayashi, K.5    Matsukura, S.6
  • 217
    • 0025781732 scopus 로고
    • Hericenones C, D and E, stimulators of nerve gorwth factor (NGF)-synthesis, from the mushroom Hericium erinaceum
    • Kawagishi H, Ando M, Sakamoto H, Yoshida S, Ojima F, et al. 1991. Hericenones C, D and E, stimulators of nerve gorwth factor (NGF)-synthesis, from the mushroom Hericium erinaceum. Tetrahedron Lett. 32:4561-64
    • (1991) Tetrahedron Lett. , vol.32 , pp. 4561-4564
    • Kawagishi, H.1    Ando, M.2    Sakamoto, H.3    Yoshida, S.4    Ojima, F.5
  • 218
    • 0027636875 scopus 로고
    • Stimulation of nerve growth factor production by pyrroloquinoline quinone and its derivatives in vitro and in vivo
    • Yamaguchi K, Sasano A, Urakami T, Tsuji T, Kondo K. 1993. Stimulation of nerve growth factor production by pyrroloquinoline quinone and its derivatives in vitro and in vivo. Biosci. Biotech. Biochem. 57:1231-33
    • (1993) Biosci. Biotech. Biochem. , vol.57 , pp. 1231-1233
    • Yamaguchi, K.1    Sasano, A.2    Urakami, T.3    Tsuji, T.4    Kondo, K.5
  • 219
    • 0028343519 scopus 로고
    • Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats
    • Nita A, Murakami Y, Furukawa Y, Kawatsura W, Hayashi K, et al. 1994. Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 349:401-7
    • (1994) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.349 , pp. 401-407
    • Nita, A.1    Murakami, Y.2    Furukawa, Y.3    Kawatsura, W.4    Hayashi, K.5
  • 220
    • 0026633419 scopus 로고
    • 1,1,3 Tricyano-2-amino-1-propene (Triap) stimulates choline acetyltransferase activity in vitro and in vivo
    • Paul JW, DaVanzo JP. 1992. 1,1,3 Tricyano-2-amino-1-propene (Triap) stimulates choline acetyltransferase activity in vitro and in vivo. Dev. Brain Res. 67:113-20
    • (1992) Dev. Brain Res. , vol.67 , pp. 113-120
    • Paul, J.W.1    DaVanzo, J.P.2
  • 221
    • 0026595572 scopus 로고
    • Neutrophic sesquiterpene-neoligans from Magnolia obovata: Structure and neurotrophic activity
    • Fukuyama Y, Otoshi Y, Nakamura K, Kodama M, Nagasawa M, et al. 1992. Neutrophic sesquiterpene-neoligans from Magnolia obovata: structure and neurotrophic activity. Tetrahedron Lett. 48: 377-92
    • (1992) Tetrahedron Lett. , vol.48 , pp. 377-392
    • Fukuyama, Y.1    Otoshi, Y.2    Nakamura, K.3    Kodama, M.4    Nagasawa, M.5
  • 222
    • 0028293541 scopus 로고
    • Erinacines A, B and C, strong stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum
    • Kawagishi H, Shimada A, Shirai R, Okamoto K, Ojima F, et al. 1994. Erinacines A, B and C, strong stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum. Tetrahedron Lett. 35:1569-72
    • (1994) Tetrahedron Lett. , vol.35 , pp. 1569-1572
    • Kawagishi, H.1    Shimada, A.2    Shirai, R.3    Okamoto, K.4    Ojima, F.5
  • 223
    • 85007974480 scopus 로고
    • Stimulation of nerve growth factor production by diterpenoids isolated from plants of Euphorbia species
    • Yamaguchi K, Uemura D, Tsuji T, Kondo K. 1994. Stimulation of nerve growth factor production by diterpenoids isolated from plants of Euphorbia species. Biosci. Biotech. Biochem. 58:1749-51
    • (1994) Biosci. Biotech. Biochem. , vol.58 , pp. 1749-1751
    • Yamaguchi, K.1    Uemura, D.2    Tsuji, T.3    Kondo, K.4
  • 224
    • 0028936727 scopus 로고
    • Evidence for nerve growth factor-potentiating activities of the non-peptidic compound SR 57746A in PC12 cells
    • Pradines A, Magazin M, Schiltz P, Le Fur G, Caput D, Ferrara P. 1995. Evidence for nerve growth factor-potentiating activities of the non-peptidic compound SR 57746A in PC12 cells. J Neurochem. 64:1954-64
    • (1995) J Neurochem. , vol.64 , pp. 1954-1964
    • Pradines, A.1    Magazin, M.2    Schiltz, P.3    Le Fur, G.4    Caput, D.5    Ferrara, P.6
  • 226
    • 0026595294 scopus 로고
    • K-252 compounds: Modulators of neurotrophin signal transmission
    • Knüsel B, Hefti F. 1992. K-252 compounds: modulators of neurotrophin signal transmission. J. Neurochem. 59:1987-96
    • (1992) J. Neurochem. , vol.59 , pp. 1987-1996
    • Knüsel, B.1    Hefti, F.2
  • 227
    • 0026710816 scopus 로고
    • K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3
    • Knüsel B, Kaplan DR, Winslow JW, Rosenthal A, Burton LE, et al. 1992. K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3. J. Neurochem. 59:715-22
    • (1992) J. Neurochem. , vol.59 , pp. 715-722
    • Knüsel, B.1    Kaplan, D.R.2    Winslow, J.W.3    Rosenthal, A.4    Burton, L.E.5
  • 228
    • 0026684676 scopus 로고
    • Inhibition of the cellular actions of nerve growth factor by staurosporine and K-252a results from the attenuation of the activity of the trk tyrosine kinase
    • Ohmichi M, Decker SJ, Pang L, Saltiel AR. 1992. Inhibition of the cellular actions of nerve growth factor by staurosporine and K-252a results from the attenuation of the activity of the trk tyrosine kinase. Biochemistry 31:4034-39
    • (1992) Biochemistry , vol.31 , pp. 4034-4039
    • Ohmichi, M.1    Decker, S.J.2    Pang, L.3    Saltiel, A.R.4
  • 229
    • 0342433104 scopus 로고
    • Comparison of the pharmacological actions of CEP1347 to nerve growth factor in rats with lesions of the nucleus basalis magnocellularis
    • Saporito MS, Brown ER, Haun F, Miller M, Murakata C, et al. 1995. Comparison of the pharmacological actions of CEP1347 to nerve growth factor in rats with lesions of the nucleus basalis magnocellularis. Abstr. Soc. Neurosci. 25:112
    • (1995) Abstr. Soc. Neurosci. , vol.25 , pp. 112
    • Saporito, M.S.1    Brown, E.R.2    Haun, F.3    Miller, M.4    Murakata, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.