AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans

Anesthesiology

Volumn 89, Issue 5, 1998, Pages 1060-1067

  Sang, Christine N ^a   Hostetter, Meredith P ^b   Gracely, Richard H ^b   Chappell, Amy S ^b   Schoepp, Darryle D ^b   Lee, Gloria ^b   Whitcup, Scott ^b   Caruso, Rafael ^b   Max, Mitchell B ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

Allodynia; Glutamate; Nociception; Sensory testing

Indexed keywords

AMPA RECEPTOR ANTAGONIST; CAPSAICIN; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; KAINIC ACID RECEPTOR ANTAGONIST;

ADULT; ALLODYNIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; INTRADERMAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NOCICEPTION; NORMAL HUMAN; PAIN; PAIN THRESHOLD; PRICK TEST; PRIORITY JOURNAL; SOMNOLENCE; TEMPERATURE SENSE; VISUAL IMPAIRMENT;

EID: 0031771639     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199811000-00005     Document Type: Article

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