Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke

Stroke

Volumn 32, Issue 11, 2001, Pages 2635-2640

  Morris, Daniel C ^a   Zhang, Li ^b   Zhang, Zheng Gang ^b   Lu, Mei ^a   Berens, Kurt L ^c   Brown, Philip M ^e   Chopp, Michael ^b,d  

^a HENRY FORD HEALTH SCIENCES CENTER   (United States)

^b HENRY FORD HOSPITAL   (United States)

^c TEXAS BIOTECHNOLOGY CORPORATION   (United States)

^d OAKLAND UNIVERSITY   (United States)

^e NONE

Author keywords

Cerebral ischemia; Rats; Stroke; Thrombin; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; ARGATROBAN; FIBRIN; ANTITHROMBIN; PIPECOLIC ACID DERIVATIVE; RECOMBINANT PROTEIN; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EMBOLISM; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; FIBRIN DEPOSITION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; TREATMENT OUTCOME; TREATMENT PLANNING; ANIMAL; CEREBRAL ARTERY DISEASE; CEREBROVASCULAR ACCIDENT; GENETICS; INCIDENCE; PATHOLOGY; RAT STRAIN; TIME;

ANIMAL; ANTITHROMBINS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRIN; INCIDENCE; INFARCTION, MIDDLE CEREBRAL ARTERY; INTRACRANIAL EMBOLISM; MALE; PIPECOLIC ACIDS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0035168889     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/hs1101.097390     Document Type: Article

References (39)

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