Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth

Neuron

Volumn 24, Issue 3, 1999, Pages 585-593

  Yamashita, Toshihide ^a   Tucker, Kerry Lee ^a   Barde, Yves Alain ^a  

^a MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN; NEUROTROPHIN RECEPTOR; RHO FACTOR;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; HORMONE RECEPTOR INTERACTION; IMMUNOCYTOCHEMISTRY; LIGAND BINDING; NERVE FIBER GROWTH; NEURITE; NONHUMAN; PRIORITY JOURNAL; RETINA DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0033230625     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)81114-9     Document Type: Article

References (55)

1. Aktories, K., Weller, U., and Chhatwal, G.S. (1987). Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin. FEBS Lett. 212, 109-113.
2. Anton, E.S., Weskamp, G., Reichardt, L.F., and Matthew, W.D. (1994). Nerve growth factor and its low affinity receptor promote Schwann cell migration. Proc. Natl. Acad. Sci. USA 91, 2795-2799.
3. Bamji, S.X., Majdan, M., Pozniak, C.D., Belliveau, D.J., Aloyz, R., Kohn, J., Causing, C.G., and Miller, F.D. (1998). The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140, 911-923.
4. NTR. EMBO J. 18, 616-622.
5. Boguski, M.S., and McCormick, F. (1993). Proteins regulating Ras and its relatives. Nature 366, 643-654.
6. Borasio, G.D., John, J., Wittinghofer, A., Barde, Y.A., Sendtner, M., and Heumann, R. (1989). ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons. Neuron 2, 1087-1096.
7. Bothwell, M. (1995). Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18, 223-253.
8. Brennan, C., Rivas-Plata, K., and Landis, S.C. (1999). The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo. Nat. Neurosci. 2, 699-705.
9. Buck, C.R., Martinez, H.J., Black, I.B., and Chao, M.V. (1987). Developmentally regulated expression of the nerve growth factor receptor gene in the periphery and brain. Proc. Natl. Acad. Sci. USA 84, 3060-3063.
10. Carter, B.D., Kaltschmidt, C, Kaltschmidt, B, Offenhauser, N., Bohm-Matthaei, R., Baeuerle, P.A., and Barde, Y.A. (1996). Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75. Science 272, 542-545.
11. Casaccia-Bonnefil, P., Carter, B.D., Dobrowsky, R.T., and Chao, M.V. (1996). Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383, 716-719.
12. NTR and participates in programmed cell death. EMBO J. 18, 6050-6061.
13. Collins, F., and Dawson, A. (1983). An effect of nerve growth factor on parasympathetic neurite outgrowth. Proc. Natl. Acad. Sci. USA 80, 2091-2094.
14. Crespo, P., Schuebel, K.E., Ostom, A.A., Gutkind, J.S., and Bustelo, X.R. (1997). Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 385, 169-172.
15. Davey, F., and Davies, A.M. (1998). TrkB signaling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic propioceptive neurons. Curr. Biol. 8, 915-918.
16. Davies, A.M., Horton, A., Burton, L.E., Schmelzer, C., Vandlen, R., and Rosenthal, A. (1993). Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons. J. Neurosci. 13, 4961-4967.
17. NTR. Curr. Opin. Neurobiol. 7, 413-418.
18. Dobrowsky, R.T., Werner, M.H., Castellino, A.M., Chao, M.V., and Hannun, Y.A. (1994). Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265, 1596-1599.
19. Ernfors, P., Hallbook, F., Ebendal, T., Shooter, E.M., Radeke, M.J., Misko, T.P., and Persson, H. (1988). Developmental and regional expression of beta-nerve growth factor receptor mRNA in the chick and rat. Neuron 1, 983-996.
20. Ernfors, P., Henschen, A., Olson, L., and Persson, H. (1989). Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron 2, 1605-1613.
21. Fariñas, I., Yoshida, C.K., Backus, C., and Reichardt, L.F. (1996). Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursors. Neuron 17, 1065-1078.
22. Feinstein, D.L., and Larhammar, D. (1990). Identification of a conserved protein motif in a group of growth factor receptors. FEBS Lett. 272, 7-11.
23. Frade, J.M., and Barde, Y.-A. (1999). Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 126, 683-690.
24. Frade, J.M., Rodriguez-Tebar, A., and Barde, Y.A. (1996). Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383, 166-168.
25. Gallo, G., and Letourneau, P.C. (1998). Axon guidance: GTPases help axons reach their targets. Curr. Biol. 8, R80-R82.
26. Gomez, J., Martinez, C., Gonzalez, A., and Rebollo, A. (1998). Dual role of ras and rho proteins: at the cutting edge of life and death. Immunol. Cell Biol. 76, 125-134.
27. 0. J. Biol. Chem. 266, 12655-12661.
28. Hotchin, N.A., and Hall, A. (1996). Regulation of the actin cytoskelton, integrins and cell growth by the Rho family of small GTPases. Cancer Surv. 27, 311-322.
29. Jin, Z., and Strittmatter, S.M. (1997). Rac1 mediates collapsin-1-induced growth cone collapse. J. Neurosci. 17, 6256-6263.
30. Khursigara, G., Orlinick, J.R., and Chao, M.V. (1999). Association of the p75 neurotrophin receptor with TRAF6. J. Biol. Chem. 274, 2597-2600.
31. Koch, G., Haberman, B., Mohr, C., Just, I., and Aktories, K. (1991). Interaction of mastoparan with the low molecular mass GTP-binding proteins rho/rac. FEBS Lett. 291, 336-340.
32. Koch, G., Mohr, C., Just, I., and Aktories, K. (1992). Posttranslational isoprenylation of rho protein is a prerequisite for its interaction with mastoparan and other amphiphilic agents. Biochem. Biophys. Res. Commun. 186, 448-454.
33. Large, T.H., Weskamp, G., Helder, J.C., Redeke, M.J., Misko, T.P., Shooter, E.M., and Reichardt, L.F. (1989). Structure and developmental expression of the nerve growth factor receptor in the chicken central nervous system. Neuron 2, 1123-1134.
34. Laudanna, C., Campbell, J.J., and Butcher, E.C. (1996). Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science 271, 981-983.
35. Lee, H.J., Hammond, D.N., Large, T.H., Roback, J.D., Sim, J.A., Brown, D.A., Otten, U.H., and Wainer, B.H. (1990). Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice. J. Neurosci. 10, 1779-1787.
36. Lee, K.-F., Li, E., Huber, J., Landis, S.C., Sharpe, A.H., Chao, M.V., and Jaenisch, R. (1992). Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69, 737-749.
37. Lee, K.-F., Bachman, K., Landis, S., and Jaenisch, R. (1994). Dependence on p75 for innervation of some sympathetic targets. Science 263, 1447-1449.
38. Lee, K.-F., Simon, H., Chen, H., Bates, B., Hung, M.-C., and Hauser, C. (1995). Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 378, 394-398.
39. Liepinsh, E., Ilag, L.L., Otting, G., and Ibanez, C.F. (1997). NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J. 16, 4999-5005.
40. Liu, J.P., and Jessell, T.M. (1998). A role for RhoB in the delamination of neural crest cells from the dorsal neural tube. Development 125, 5055-5067.
41. Mackay, D.J.G., and Hall, A. (1998). Rho GTPases. J. Biol. Chem. 273, 20685-20688.
42. Mahadeo, D., Kaplan, L., Chao, M.V., and Hempstead, B.L. (1994). High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors. J. Biol. Chem. 269, 6884-6891.
43. Moody, S.A., Quigg, M.S., and Frankfurter, A. (1989). Development of the peripheral trigeminal system in the chick revealed by an isotype-specific anti-beta-tubulin monoclonal antibody. J. Comp. Neurol. 279, 567-580.
44. Nagata, S. (1997). Apoptosis by death factor. Cell 88, 355-365.
45. Narumiya, S., Sekine, A., and Fujiwara, M. (1988). Substrate for botulinum ADP-ribosyltransferase, Gb, has an amino acid sequence homologous to a putative rho gene product. J. Biol. Chem. 263, 17255-17257.
46. Nobes, C.D., and Hall, A. (1995). Rho, rac1, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia and filopodia. Cell 81, 53-62.
47. Rabizadeh, S., Oh, J., Zhong, L.T., Bitler, C.M., Butcher, L.L., and Bredesen, D.E. (1993). Induction of apoptosis by the low-affinity NGF receptor. Science 261, 345-348.
48. Ren, X.D., Kiosses, W.B., and Schwartz, M.A. (1999). Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskelton. EMBO J. 18, 578-585.
49. Ridley, A.J., and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
50. Schröpel, A., von Schack, D., Dechant, G., and Barde, Y.A. (1995). Early expression of the nerve growth factor receptor ctrkA in chick sympathetic and sensory ganglia. Mol. Cell. Neurosci. 6, 544-566.
51. Stemple, D.L., and Anderson, D.J. (1992). Isolation of a stem cell for neurons and glia from the mammalian neural crest. Cell 71, 973-985.
52. Stucky, C.L., and Koltzenburg, M. (1997). The low-affinity neurotrophin receptor p75 regulates the function but not the selective survival of specific subpopulations of sensory neurons. J. Neurosci. 17, 4398-4405.
53. Vojtek, A.B., Hollenberg, S.M., and Cooper, J.A. (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74, 205-214.
54. von Bartheld, C.S., Heuer, J.G., and Bothwell, M. (1991). Expression of nerve growth factor (NGF) receptors in the brain and retina of chick embryos: comparison with cholinergic development. J. Comp. Neurol. 310, 103-129.
55. Yan, Q., and Johnson, E.M., Jr. (1988). An immunohistochemical study of the nerve growth factor receptor in developing rats. J. Neurosci. 8, 3481-3498.