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Volumn 359, Issue 2-3, 1998, Pages 251-260

Neuroprotective effect of 5-HT(1A) receptor agonist, Bayx3702, demonstrated in vitro and in vivo

Author keywords

Bayx3702; Excitotoxicity; Glutamate; Hippocampal cell; Permanent focal ischemia; Rat

Indexed keywords

GLUTAMIC ACID; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; REPINOTAN; SEROTONIN 1 AGONIST; SEROTONIN 1A RECEPTOR;

EID: 0032561474     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00634-7     Document Type: Article
Times cited : (91)

References (51)
  • 1
    • 0031589608 scopus 로고    scopus 로고
    • 1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo
    • 1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo. Brain Res. 777:1997;179-186.
    • (1997) Brain Res. , vol.777 , pp. 179-186
    • Ahlemeyer, B.1    Krieglstein, J.2
  • 3
    • 0025924342 scopus 로고
    • 1A receptors mediate opposing responses on membrane excitability in rat association cortex
    • 1A receptors mediate opposing responses on membrane excitability in rat association cortex. Neuroscience. 40:1991;399-412.
    • (1991) Neuroscience , vol.40 , pp. 399-412
    • Araneda, R.1    Andrade, R.2
  • 4
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 5
    • 0025194422 scopus 로고
    • S-100β but not NGF, EGF, insulin, or calmodulin is a serotonergic growth factor
    • Azmitia E.C., Dolan K., Whitaker-Azmitia P.M. S-100β but not NGF, EGF, insulin, or calmodulin is a serotonergic growth factor. Brain Res. 516:1990;354-356.
    • (1990) Brain Res. , vol.516 , pp. 354-356
    • Azmitia, E.C.1    Dolan, K.2    Whitaker-Azmitia, P.M.3
  • 7
    • 0028986275 scopus 로고
    • S-100β protects hippocampal neurons from damage induced by glucose deprivation
    • Barger S.W., van Eldik L.J., Mattson M.P. S-100β protects hippocampal neurons from damage induced by glucose deprivation. Brain Res. 677:1995;167-170.
    • (1995) Brain Res. , vol.677 , pp. 167-170
    • Barger, S.W.1    Van Eldik, L.J.2    Mattson, M.P.3
  • 8
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentration of glutamate and aspartate in rat hippocampus during cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H., Drejer J., Schousboe A., Diemer N.H. Elevation of the extracellular concentration of glutamate and aspartate in rat hippocampus during cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1974.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1974
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 9
    • 0025647630 scopus 로고
    • 1A agonists: A new therapeutic principle for stroke treatment
    • 1A agonists: a new therapeutic principle for stroke treatment. Stroke. 21(Suppl. IV):1990;161-163.
    • (1990) Stroke , vol.21 , Issue.SUPPL. IV , pp. 161-163
    • Bielenberg, G.W.1    Burkhardt, M.2
  • 10
    • 0025685410 scopus 로고
    • 1A agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil
    • 1A agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil. Stroke. 21(Suppl. IV):1990;164-166.
    • (1990) Stroke , vol.21 , Issue.SUPPL. IV , pp. 164-166
    • Bode-Greuel, K.M.1    Klisch, J.2    Horvath, E.3    Glaser, T.4    Traber, J.5
  • 12
    • 0025944364 scopus 로고
    • 1A binding in rat brain - A combined in situ hybridization/in vitro receptor autoradiographic study
    • 1A binding in rat brain - a combined in situ hybridization/in vitro receptor autoradiographic study. Brain Res. 561:1991;51-60.
    • (1991) Brain Res. , vol.561 , pp. 51-60
    • Chalmers, D.T.1    Watson, S.J.2
  • 13
    • 0029908958 scopus 로고    scopus 로고
    • + currents in rat serotonergic neurones
    • + currents in rat serotonergic neurones. J. Physiol. 496:1996;120-137.
    • (1996) J. Physiol. , vol.496 , pp. 120-137
    • Chen, Y.1    Penington, N.J.2
  • 14
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-643.
    • (1988) Neuron , vol.1 , pp. 623-643
    • Choi, D.W.1
  • 15
    • 0023233048 scopus 로고
    • Two distinct effects of 5-hydrohytryptamine on single cortical neurons
    • Davies M.F., Deisz R.A., Prince D.A., Peroutka S.J. Two distinct effects of 5-hydrohytryptamine on single cortical neurons. Brain Res. 423:1987;247-352.
    • (1987) Brain Res. , vol.423 , pp. 247-352
    • Davies, M.F.1    Deisz, R.A.2    Prince, D.A.3    Peroutka, S.J.4
  • 16
    • 0023153653 scopus 로고
    • Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia
    • Desphande J.K., Siesjö B.K., Wieloch T. Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia. J. Cereb. Blood Flow Metab. 7:1987;89-95.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 89-95
    • Desphande, J.K.1    Siesjö, B.K.2    Wieloch, T.3
  • 17
    • 0028990742 scopus 로고
    • 1A receptor agonists: Recent developments and controversial issues
    • 1A receptor agonists: recent developments and controversial issues. Psychopharmacology. 121:1995;1-26.
    • (1995) Psychopharmacology , vol.121 , pp. 1-26
    • De Vry, J.1
  • 19
    • 0025939163 scopus 로고
    • Perspective in S-100 protein biology
    • Donato R. Perspective in S-100 protein biology. Cell Calcium. 12:1991;713-726.
    • (1991) Cell Calcium , vol.12 , pp. 713-726
    • Donato, R.1
  • 21
    • 0030565026 scopus 로고    scopus 로고
    • 2+ concentration can be useful tool to predict neuronal damage and neuroprotective properties of drugs
    • 2+ concentration can be useful tool to predict neuronal damage and neuroprotective properties of drugs. Brain Res. 732:1996;87-94.
    • (1996) Brain Res. , vol.732 , pp. 87-94
    • Ferger, D.1    Krieglstein, J.2
  • 22
    • 0029864289 scopus 로고    scopus 로고
    • Serotonin modulates N- And P-type calcium currents in neocortical pyramidal neurons via a membrane-deliminited pathway
    • Foehring R.C. Serotonin modulates N- and P-type calcium currents in neocortical pyramidal neurons via a membrane-deliminited pathway. J. Neurophysiol. 75:1996;648-659.
    • (1996) J. Neurophysiol , vol.75 , pp. 648-659
    • Foehring, R.C.1
  • 24
    • 0027442646 scopus 로고
    • Hippocampal serotonin levels influence the expression of S-100β detected by immunocytochemistry
    • Haring J.H., Hagan A., Olson J., Rodgers B. Hippocampal serotonin levels influence the expression of S-100β detected by immunocytochemistry. Brain Res. 631:1993;119-123.
    • (1993) Brain Res. , vol.631 , pp. 119-123
    • Haring, J.H.1    Hagan, A.2    Olson, J.3    Rodgers, B.4
  • 25
    • 0000204469 scopus 로고    scopus 로고
    • 1A receptor agonist BAY×3702 in a rat model of permanent focal cerebral ischemia and traumatic brain injury
    • 1A receptor agonist BAY×3702 in a rat model of permanent focal cerebral ischemia and traumatic brain injury. Soc. Neurosci. Abstr. 23:1997;1923.
    • (1997) Soc. Neurosci. Abstr. , vol.23 , pp. 1923
    • Horvath, E.1    Augstein, K.-H.2    Wittka, R.3
  • 27
    • 0023877523 scopus 로고
    • Vulnerability of cultured cortical neurons to damage by excitotoxins: Differential susceptibility of neurons containing NADPH-diaphorase
    • Koh J.I., Choi D.W. Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase. J. Neurosci. 8:1988;2153-2163.
    • (1988) J. Neurosci. , vol.8 , pp. 2153-2163
    • Koh, J.I.1    Choi, D.W.2
  • 28
    • 0029563462 scopus 로고
    • Changes in levels of monoamines and their metabolites in incompletely ischemic brains of spontaneously hypertensive rats
    • Kozuka M., Iwata N. Changes in levels of monoamines and their metabolites in incompletely ischemic brains of spontaneously hypertensive rats. Neurochem. Res. 20:1995;1429-1435.
    • (1995) Neurochem. Res. , vol.20 , pp. 1429-1435
    • Kozuka, M.1    Iwata, N.2
  • 30
    • 0026673153 scopus 로고
    • S-100β and insulin-like growth factor-II differentially regulate growth of developing serotonin and dopamine neurons in vitro
    • Liu J.P., Lauder J.M. S-100β and insulin-like growth factor-II differentially regulate growth of developing serotonin and dopamine neurons in vitro. J. Neurosci. Res. 33:1992;248-256.
    • (1992) J. Neurosci. Res. , vol.33 , pp. 248-256
    • Liu, J.P.1    Lauder, J.M.2
  • 33
    • 0025170541 scopus 로고
    • Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn of the rat
    • Murase K., Randic M., Shirasaki T., Nakagawa T., Akaike N. Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn of the rat. Brain Res. 525:1990;84-91.
    • (1990) Brain Res. , vol.525 , pp. 84-91
    • Murase, K.1    Randic, M.2    Shirasaki, T.3    Nakagawa, T.4    Akaike, N.5
  • 35
    • 0002317332 scopus 로고
    • 1A agonist CM57493 on infarct area, infarct volume and hippocampal neuronal damage after focal and global cerebral ischemia in mice and rats
    • In: Krieglstein, J., Oberpichler, H. (Eds.), Wissenschaftliche Verlagsgesellschaft Stuttgart
    • 1A agonist CM57493 on infarct area, infarct volume and hippocampal neuronal damage after focal and global cerebral ischemia in mice and rats. In: Krieglstein, J., Oberpichler, H. (Eds.), Pharmacology of Cerebral Ischemia 1990. Wissenschaftliche Verlagsgesellschaft Stuttgart, pp. 493-497.
    • (1990) Pharmacology of Cerebral Ischemia 1990 , pp. 493-497
    • Nuglisch, J.1    Karkoutly, C.2    Peruche, B.3    Prehn, J.H.M.4    Welsch, M.5    Mennel, H.D.6    Roßberg, C.7    Krieglstein, J.8
  • 36
    • 0022346190 scopus 로고
    • Quantitative autoradiographic maping of serotonin receptors in rat brain: I. Serotonin-1 receptors
    • Pazos A., Palacios M. Quantitative autoradiographic maping of serotonin receptors in rat brain: I. Serotonin-1 receptors. Brain Res. 346:1985;205-230.
    • (1985) Brain Res. , vol.346 , pp. 205-230
    • Pazos, A.1    Palacios, M.2
  • 37
    • 0025919695 scopus 로고
    • 2+ current inhibition produced by serotonin in rat dorsal raphe neurons
    • 2+ current inhibition produced by serotonin in rat dorsal raphe neurons. J. Neurosci. 11:1991;3594-3609.
    • (1991) J. Neurosci. , vol.11 , pp. 3594-3609
    • Penington, N.J.1    Kelly, J.S.2    Fox, A.P.3
  • 38
    • 0028991683 scopus 로고
    • 1A receptor agonists, 8-OH-DPAT, buspirone and flesinoxan, upon brain damage induced by transient global cerebral ischemia in gerbils
    • 1A receptor agonists, 8-OH-DPAT, buspirone and flesinoxan, upon brain damage induced by transient global cerebral ischemia in gerbils. Arch. Int. Pharmacodyn. Ther. 329:1995;347-359.
    • (1995) Arch. Int. Pharmacodyn. Ther. , vol.329 , pp. 347-359
    • Piera, M.J.1    Massingham, R.2    Michelin, M.T.3    Beaughard, M.4
  • 39
    • 0027493547 scopus 로고
    • Effects of serotoninergic drugs in experimental brain ischemia: Evidence for a protective role of serotonin in cerebral ischemia
    • Prehn J.H.M., Welsch M., Backhauß C., Nuglisch J., Ausmeier F., Karkoutly C., Krieglstein J. Effects of serotoninergic drugs in experimental brain ischemia: evidence for a protective role of serotonin in cerebral ischemia. Brain Res. 630:1993;10-20.
    • (1993) Brain Res. , vol.630 , pp. 10-20
    • Prehn, J.H.M.1    Welsch, M.2    Backhauß, C.3    Nuglisch, J.4    Ausmeier, F.5    Karkoutly, C.6    Krieglstein, J.7
  • 40
    • 0027513828 scopus 로고
    • Brain damage caused by ischemia: Pathophysiological and pharmacological aspects
    • Rami A., Krieglstein J. Brain damage caused by ischemia: pathophysiological and pharmacological aspects. Dementia. 4:1993;21-31.
    • (1993) Dementia , vol.4 , pp. 21-31
    • Rami, A.1    Krieglstein, J.2
  • 41
    • 0002073872 scopus 로고
    • 1A receptor agonists on the glutamate-induced rise in cytosolic calcium concentration as well as on calcium and potassium currents in hippocampal neurons
    • In: Krieglstein, J., Oberpichler-Schwenk, H. (Eds.), Medpharm Scientific Publishers, Stuttgart
    • 1A receptor agonists on the glutamate-induced rise in cytosolic calcium concentration as well as on calcium and potassium currents in hippocampal neurons. In: Krieglstein, J., Oberpichler-Schwenk, H. (Eds.), Pharmacology of Cerebral Ischemia 1994. Medpharm Scientific Publishers, Stuttgart, pp. 89-94.
    • (1994) Pharmacology of Cerebral Ischemia 1994 , pp. 89-94
    • Rupalla, K.1    Jakob, R.2    Krieglstein, J.3
  • 42
    • 0018910610 scopus 로고
    • The action of serotonin in rat hippocampal slice preparation
    • Segal M. The action of serotonin in rat hippocampal slice preparation. J. Physiol. 303:1980;423-439.
    • (1980) J. Physiol. , vol.303 , pp. 423-439
    • Segal, M.1
  • 44
    • 0024556434 scopus 로고
    • Calcium fluxes, calcium antagonists and calcium related pathology in brain ischemia, hypoglycemia and spreading depression - A unifying hypothesis
    • Siesjö B.K., Bengtsson F. Calcium fluxes, calcium antagonists and calcium related pathology in brain ischemia, hypoglycemia and spreading depression - a unifying hypothesis. J. Cereb. Blood Flow Metab. 9:1989;127-140.
    • (1989) J. Cereb. Blood Flow Metab. , vol.9 , pp. 127-140
    • Siesjö, B.K.1    Bengtsson, F.2
  • 45
    • 0021743001 scopus 로고
    • Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain
    • Simon R.P., Swans J.H., Griffith T., Meldrum B.S. Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science. 226:1984;850-852.
    • (1984) Science , vol.226 , pp. 850-852
    • Simon, R.P.1    Swans, J.H.2    Griffith, T.3    Meldrum, B.S.4
  • 46
    • 0019868418 scopus 로고
    • Focal cerebral ischemia in the rat: 1. Description of the technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura A., Graham D.I., McCulloch J., Teasdale G.M. Focal cerebral ischemia in the rat: 1. Description of the technique and early neuropathological consequences following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 1:1981;53-60.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 47
    • 0028057318 scopus 로고
    • Neuro-glial neurotrophic interaction in the S-100β retarded mutant mouse (Polydactyly Nagoya): II. Co-cultures study
    • Ueda S., Hou X.P., Whitaker-Azmitia P.M., Azmitia E.C. Neuro-glial neurotrophic interaction in the S-100β retarded mutant mouse (Polydactyly Nagoya): II. Co-cultures study. Brain Res. 633:1994;284-288.
    • (1994) Brain Res. , vol.633 , pp. 284-288
    • Ueda, S.1    Hou, X.P.2    Whitaker-Azmitia, P.M.3    Azmitia, E.C.4
  • 48
    • 0023059503 scopus 로고
    • Autoregulation of fetal serotonergic neuronal development: Role of high-affinity serotonin receptors
    • Whitaker-Azmitia P.M., Azmitia E.C. Autoregulation of fetal serotonergic neuronal development: role of high-affinity serotonin receptors. Neurosci. Lett. 67:1986;307-311.
    • (1986) Neurosci. Lett. , vol.67 , pp. 307-311
    • Whitaker-Azmitia, P.M.1    Azmitia, E.C.2
  • 49
    • 0025196891 scopus 로고
    • 1A receptors releases the serotonergic growth factor, protein S-100 and alters glial morpholigy
    • 1A receptors releases the serotonergic growth factor, protein S-100 and alters glial morpholigy. Brain Res. 528:1990;155-158.
    • (1990) Brain Res. , vol.528 , pp. 155-158
    • Whitaker-Azmitia, P.M.1    Murphy, R.2    Azmitia, E.C.3
  • 50
    • 0028985633 scopus 로고
    • Comparative localization of serotonin 1A, 1C and 2 receptor subtype mRNA in rat brain
    • Wright D.E., Seroogy K.B., Lundgren K.H., Davis B.M., Jennes L. Comparative localization of serotonin 1A, 1C and 2 receptor subtype mRNA in rat brain. J. Comp. Neurol. 351:1995;357-373.
    • (1995) J. Comp. Neurol. , vol.351 , pp. 357-373
    • Wright, D.E.1    Seroogy, K.B.2    Lundgren, K.H.3    Davis, B.M.4    Jennes, L.5
  • 51
    • 0031579428 scopus 로고
    • 1A receptors mediate neurotrophic effect of serotonin on developing dentate granule cells
    • 1A receptors mediate neurotrophic effect of serotonin on developing dentate granule cells. Dev. Brain Res. 98:1995;185-190.
    • (1995) Dev. Brain Res. , vol.98 , pp. 185-190
    • Yan, W.1    Wilson, C.C.2    Haring, J.H.3


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