Methylphenidate in early poststroke recovery: A double-blind, placebo- controlled study

Archives of Physical Medicine and Rehabilitation

Volumn 79, Issue 9, 1998, Pages 1047-1050

  Grade, Charles ^a,c   Redford, Becky ^c   Chrostowski, Jay ^a,c   Toussaint, Loren ^b   Blackwell, Barry ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c AURORA SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPHENIDATE; PLACEBO;

ADULT; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERANCE; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; MALE; MOTOR PERFORMANCE; PHYSIOTHERAPY; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; STROKE;

EID: 0031656504     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9993(98)90169-1     Document Type: Article

References (26)

1. Robinson RG, Starr LB, Kubos KL, Price TR. A two year longitudinal study of post-stroke mood disorders: findings during the initial evaluation. Stroke 1983;14:736-41.
2. Beckson M, Cummings JL. Neuropsychiatrie aspects of stroke. Int J Psychiatry Med 1991;21:1-15.
3. Lipsey JR, Robinson RG, Pearigin GD, Rad K, Price TR. Nortriptyline treatment of post-stroke depression: a double-blind study. Lancet 1985;1:297-300.
4. Reding MJ, Orto LA, Winter SW, Fortuna IM, Di Ponte P, Mcdowell FH. Antidepressant therapy after stroke, a double-blind trial. Arch Neurol 1986;43:763-5.
5. Lingam VR, Lazarus LW, Groves L, Oh SH. Methylphenidate in treating post-stroke depression. J Clin Psychiatry 1988;49:151-3.
6. Feeney DM, Gonzales A, Law WA. Amphetamine, haloperidol and experience affect rate of recovery with motor cortex injury. Science 1982;271:855-7.
7. Crisostomo EA, Duncan PW, Probst M, Dawson DV, Davis JN. Evidence that amphetamine with physical therapy promotes recovery of function in stroke patients. Ann Neurol 1988;23:94-7.
8. Rosenberg PB, Ahmed I, Hurwitz S. Methylphenidate in depressed medically ill patients. J Clin Psychiatry 1991;52:263-7.
9. Kaufman MW, Cassem NH, Murray GB, Jen M. Use of stimulants in medicating patients with neurovascular disease and major depression. Can J Psychiatry 1984;29:46-9.
10. Lazarus LW, Winemiller DR, Lingram VR, Neyman I, Hartman C, Abassian M, et al. Efficacy and side effects of methylphenidate for post-stroke depression. J Clin Psychiatry 1992;53:447-9.
11. Kaufmann MW, Cassem N, Murray G. The use of methylphenidate in depressed patients after cardiac surgery. J Clin Psychiatry 1984;45:82-4.
12. Woods SW, Tesar GE, Murray GB, Cassem NH. Psychostimulant treatment of depressive disorders secondary to medical illness. J Clin Psychiatry 1986;47:12-5.
13. Physicians Desk Reference. 50th ed. Oradell (NJ): Medical Economics; 1993. Ritalin; p. 848.
14. Starr LB, Robinson RG, Price TR. Reliability, validity, and clinical utility of the social functioning exam in assessment of stroke patients. Exp Aging Res 1983;9:101.
15. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
16. Zung WWK. A self rating depression scale. Arch Gen Psychiatry 1965;12:63-70.
17. Folstein MF, Folstein SF, McHugh PR. Mini-mental state; a practical method for grading the cognitive status of patients for the clinician. J Psychiatric Res 1975;12:189-98.
18. Fugl-Meyer AR, Jaasko L, Leyman I, Olsson S, Steglind S. The post-stroke hemiplegic patient; a method for evaluation of physical performance. Scand J Rehabil Med 1975;7:13-31.
19. Hamilton BB, Laughlin JA, Fiedler RC, Granger CV. Interrater reliability of the 7-level functional independence measure (FIM). Scand J Rehabil Med 1994;26:115-9.
20. Fisher S, Greenberg RP. How sound is the double-blind design for evaluating psychotropic drags? J Nerv Ment Dis 1993;181:345-50.
21. Evans RW, Gualtieri CT, Patterson DR. Treatment of chronic closed head injury with psychostimulant drugs: a controlled case study and an appropriate evaluation procedure. J Nerv Ment Dis 1987;175:106-10.
22. Cardenas DD. Cognition-enhancing drugs. J Head Trauma Rehabil 1993;8:112-4.
23. Biel JH, Bopp BA. Amphetamines: Structure-activity relationships. In: Iverson L, Synder S, editors. Handbook of psychopharmacology, vol II. New York: Plenum Press; 1979. p. 131.
24. Robinson RG, Shoemaker WJ, Schlumpf M, Coyle JT. Effect of experimental cerebral infarction in rat brain on catecholamines and behavior. Nature 1975;255:332-4.
25. Feeney DM, Sutton RL, Boyeson MG, Robert K. The locus coeruleus and cerebral metabolism: recovery of function after cortical injury. Physiol Psych 1985;13:197-203.
26. Hovda DA, Feeney DM, Salo AA, Boyeson MG. Phenoxybenzamine but not haloperidol reinstates all motor and sensory deficits in cats fully recovered from sensorimotor cortex ablations. Soc Neurosci Abstr 1983;9:1002.