YM872, a highly water-soluble AMPA receptor antagonist, preserves the hemodynamic penumbra and reduces brain injury after permanent focal ischemia in rats

Stroke

Volumn 29, Issue 10, 1998, Pages 2141-2148

  Shimizu Sasamata, Masao ^a   Kano, Tsuneo ^a   Rogowska, Jadwiga ^a   Wolf, Gerald L ^a   Moskowitz, Michael A ^a   Lo, Eng H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cerebral ischemia, focal; Neuroprotection; Penumbra; Rats; Receptor antagonist, AMPA; Tomography, emission computed

Indexed keywords

AMPA RECEPTOR ANTAGONIST; IOHEXOL; NONIONIC CONTRAST MEDIUM; SODIUM CHLORIDE; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG; [2,3 DIOXO 7 (1H IMIDAZOL 1 YL) 6 NITRO 1,2,3,4 TETRAHYDRO 1 QUINOXALINYL] ACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; CORPUS STRIATUM; HEMODYNAMICS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031667548     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.29.10.2141     Document Type: Article

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