Cerestat and other NMDA antagonists in ischemic stroke

Neurology

Volumn 49, Issue 5 SUPPL., 1997, Pages

  Lees, Kennedy R ^a  

^a WESTERN INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APTIGANEL; ELIPRODIL; GLUTAMATE RECEPTOR ANTAGONIST; LIFARIZINE; LUBELUZOLE; NIMODIPINE;

ARTICLE; BINDING SITE; BRAIN ISCHEMIA; BRAIN PROTECTION; CLINICAL TRIAL; COMPETITIVE INHIBITION; CONFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; HALLUCINATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTENSION; MULTICENTER STUDY; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECEPTOR BLOCKING; RISK BENEFIT ANALYSIS; SEDATION; SODIUM TRANSPORT; STROKE;

EID: 0030666876     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.49.5_suppl_4.s66     Document Type: Article

References (9)

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2. Grotta J, Clark W, Coull B, et al. Safety and tolerability of the glutamate antagonist CGS 19755 (selfotel) in patients with acute ischemic stroke: results of a phase IIa randomized trial. Stroke 1995;26:602-605.
3. Diener HC, Hacke W, Hennerici M, Radberg J, Hantson L, De Keyser J. Lubeluzole in acute ischemic stroke: A double-blind, placebo-controlled phase II trial. Stroke 1996;27:76-81.
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7. Diener HC, Hacke W, Lees KR, Timmerhuis T, Haan J, Hantson L. Cardiovascular safety of lubeluzole in patients with acute ischemic stroke [abstract]. Cerebrovasc Dis 1996;6:77-P392.
8. Muir KW, Lees KR. A randomized, double-blind, placebo-controlled pilot trial of intravenous magnesium sulfate in acute stroke. Stroke 1995;26:1183-1188.
9. Dyker AG Lees KR. The safety, tolerability and pharmacokinetics of GV150526A (a novel glycine antagonist) in patients with acute ischaemic stroke. Presented at The Third International Conference on Neuroprotective Agents, 9-12 September, 1996, Varenna, Italy.