Nogo-66 receptor antagonist peptide promotes axonal regeneration

Nature

Volumn 417, Issue 6888, 2002, Pages 547-551

  GrandPré, Tadzia ^a   Shuxin, L I ^a   Strittmatter, Stephen M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; MONOCLONAL ANTIBODIES; NEUROLOGY;

LOCOMOTOR RECOVERY;

NITROGEN COMPOUNDS;

NEP 1 40; NOGO 66 RECEPTOR; NOGO 66 RECEPTOR ANTAGONIST; PEPTIDE; UNCLASSIFIED DRUG;

MEDICINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; DRUG MECHANISM; FEMALE; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL TRACT; RAT; SPINAL CORD HEMISECTION; SPINAL CORD TRANSSECTION;

AMINO ACID SEQUENCE; ANIMALS; AXONS; BINDING, COMPETITIVE; CENTRAL NERVOUS SYSTEM; CULTURE MEDIA, CONDITIONED; FEMALE; GROWTH CONES; MOLECULAR SEQUENCE DATA; MOTOR ACTIVITY; MYELIN PROTEINS; MYELIN SHEATH; NERVE REGENERATION; NEURITES; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; SPINAL CORD INJURIES;

ANIMALIA; MAMMALIA;

EID: 0037198689     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/417547a     Document Type: Article

References (14)

1. Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein
2. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
3. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1
4. Recovery from spinal cord-injury mediated by antibodies to neurite growth inhibitors
5. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
6. Inhibitor of neurite outgrowth in humans
7. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration
8. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
9. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans
10. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury
11. A sensitive and reliable locomotor rating scale for open field testing in rats
12. Neuronal and non-neuronal collapsin-1 binding sites in developing chick are distinct from other semaphorin binding sites
13. Semaphorin3A enhances endocytosis at sites of receptor-F-actin colocalization during growth cone collapse
14. Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions