NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo

Journal of Neurochemistry

Volumn 81, Issue 1, 2002, Pages 17-24

  Dagø, Lone ^a   Bonde, Christian ^b   Peters, Dan ^c   Møller, Arne ^c   Bomholt, Signe Farsø ^c   Hartz, Barbara P ^c   Meyer, Morten ^b   Drejer, Jørgen ^c   Grønborg, Mette ^a  

^a NsGene AS   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c NEUROSEARCH A S   (Denmark)

Author keywords

Intracellular signalling; Ischaemia; Neurotrophic activity; NMDA excitotoxicity; PC12 cells

Indexed keywords

5 (4 CHLOROPHENYL) 6,7,8,9 TETRAHYDRO 1H PYRROLO[3,2 H]NAPHTHALENE 2,3 DION 3 OXIME; N METHYL DEXTRO ASPARTIC ACID; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NS 1231; PROTEIN SHC; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN SLICE; CELL DIFFERENTIATION; CELL STRAIN; CONTROLLED STUDY; GERBIL; HIPPOCAMPUS; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; GERBILLINAE; HIPPOCAMPUS; INDOLES; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; N-METHYLASPARTATE; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURITES; NEURONS; NEUROPROTECTIVE AGENTS; OXIMES; PC12 CELLS; PHOSPHORYLATION; RATS; RECEPTOR, TRKA; SIGNAL TRANSDUCTION;

ANIMALIA; DION; GERBILLINAE;

EID: 0036315818     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00803.x     Document Type: Article

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